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Polymyxin combined with Ocimum gratissimum essential oil: one alternative strategy for combating polymyxin-resistant Klebsiella pneumoniae
Polymyxin combined with Ocimum gratissimum essential oil: one alternative strategy for combating polymyxin-resistant Klebsiella pneumoniae
Introduction. Multidrug-resistant infections present a critical public health due to scarce treatment options and high mor...
The impact of agar depth on antimicrobial susceptibility testing by disc diffusion
The impact of agar depth on antimicrobial susceptibility testing by disc diffusion
Introduction. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) specifies the agar depth (4±0.5 mm) ...
Synthesis of Unsymmetrical 2,4-Diaryl Substituted and 3-Bromo-2-(4-bromoalkoxy)-Derived Pyranocoumarins
A series of unsymmetrical 2,4-disubstituted pyranocoumarins and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins were syn...
A sustainable multi-component synthetic route for 2-pyrazolines via activation of greener alcohols using homogeneous Ni(II) catalysts
In this study we have reported first nickel(II)-catalyzed sustainable, eco-friendly, practical and less expensive multi-co...
Synthetic Routes to Access Dicarbonylated Aryls and Heteroaryls
1,2-dicarbonyl compounds are privileged functionalities found in natural products, pharmaceuticals, bioactive molecules, f...
Amide-Derived Enols in Enol-Ugi Reactions: Expanding Horizons for Peptidomimetic Scaffold Synthesis
A highly efficient enol-Ugi reaction of β,β-diketoamides has been developed using a novel non-heterocyclic amide-stabilize...
Synthesis and antiproliferative activity of thiazole-fused anthraquinones
Heterocyclic derivatives of anthraquinone demonstrated a high potential for the development of new antitumor compounds. In...
Electron Donor-Acceptor Complex-Initiated C-H Trifluoromethylation and Perfluoroalkylation of Enamides and Quinoxalinones
Facilitated by electron donor-acceptor (EDA) complexes, an efficient β-trifluoromethylation and perfluoroalkylation of ena...
Copper-catalyzed Tandem Cyclization Reaction of Ethynylbenzoxazinones and Thiols: Facile Construction of 2-Thiomethylene Indoles
The first successful copper-catalyzed decarboxylative cyclization reaction of ethynylbenzoxazinones and thiols has been de...
Molecular Oxygen Promoted Sustainable Synthesis of Functionalized Quinolines Using Catalytic Glucose Derived Ionic Liquid and Copper
An expedient one-pot sustainable synthesis of quinoline analogues was developed via protection-free chemo-selective oxidat...
A rapid approach to specific carbazolelactam system related to calothrixin B
Reported here is a rapid and versatile synthetic approach to the specific pentacyclic carbazolelactams related to calothri...
gem-Difluoroallene (DFA): An Emerging Versatile Synthetic Precursor to Enable Diverse Fluorinated Molecules
Organofluorine compounds are increasingly found in diverse fields, such as pharmaceuticals, agrochemicals, and materials s...
Unveiling the Reactivity of 2H‑(Thio)pyran-2-(thi)ones in Cycloaddition Reactions with Strained Alkynes through Density Functional Theory Studies
We have theoretically investigated the inverse electron demand Diels–Alder reaction of endo-bicyclo[6.1.0]nonyne (endo-BCN...
DNA aptamers for common buffer molecules: possibility of buffer interference in SELEX
During a typical aptamer selection experiment, buffer molecules are used at 10 to 50 mM, whereas target molecules could be...
Stereoselective Synthetic Approach to β‑Trifluoromethyl Vinyl Ethers and Diethers via Reaction of (E)-1,2-dichloro-3,3,3-trifluoroprop-1-ene with Phenols
A convenient method for synthesizing of β‑trifluoromethyl vinyl ethers and diethers through the base-mediated C-O coupling...
Azide-based in situ preparation of fused heterocyclic imines and their multicomponent reactions
Structurally diverse pyrroles, indoles and imidazoles bearing an N-ω-azidoalkyl moiety and an aldehyde or ketone function ...
CRAFITY score as a predictive marker for refractoriness to atezolizumab plus bevacizumab therapy in hepatocellular carcinoma: a multicenter retrospective study
CRAFITY score as a predictive marker for refractoriness to atezolizumab plus bevacizumab therapy in hepatocellular carcinoma: a multicenter retrospective study
Although atezolizumab plus bevacizumab (Atezo/Bev) therapy has been used as the preferred first-line treatment for advance...
Design, Synthesis and Application of Bipyridine-N,N’-dioxides Catalysts in Asymmetric Synthesis of Chiral Cyclopropanes
A novel type of highly efficient chiral C2-symmetric bipyridine-N,N’-dioxides ligands prepared from L-octahydroindole-2-ca...
Photoredox copper-catalyzed regioselective syntheses of allenols via HAT-mediated propargyl radical generation
Selectivity control of the reactions of propargylic and/or allenylic radicals remains particularly elusive. Here, a visibl...
Chiral synthetic unprecedented spiro[indoline-2,3'-thiophen]-3-ones via organocatalytic asymmetric sulfa-Michael/aldol cascade reaction
An asymmetric sulfa-Michael/aldol cascade reaction of 2-ylideneoxindoles with 1,4-dithiane-2,5-diol catalyzed by squaramid...
A pillar[5]arene-based three-component supramolecular copolymer for the fluorescence detection of spermine
The supramolecular polymerization of a bis-pillar[5]arene dicarboxylic acid monomer (H) in the presence of a mixture of co...
Catalyst-Free C-H Methylation of Heteroarenes Enabled by Electron Donor-Acceptor Complex Photoactivation
An efficient, additive- and catalyst -free, visible-light-driven radical C-H methylation of heteroarenes (including quinox...
Theoretical Insights into Pd-Catalyzed Dual γ-1,1-C(sp3)–H Activation of Aliphatic Carboxylic Acids: Mechanistic Pathways, Substituent Influence on Product Selectivity, Diastereoselectivity, and Additive Effects
Employing density functional theory (DFT) calculations, the study meticulously analyzes the mechanistic details of the Pd-...
Well-Defined Chiral Dinuclear Copper-Catalyzed Tandem Asymmetric Propargylic Amination-Carboxylative Cyclization Sequence to Chiral 2-Oxazolidinone Derivatives
We report a novel strategy for the synthesis of chiral 2-oxazolidinones via a dinuclear copper-catalyzed asymmetric propar...
Visible light-induced aerobic photooxidative cleavage of C(sp3)–C(sp2) σ-bonds of allylarenes
The development of the C–C bond cleavage of allylarenes is of vital importance. However, the cleavage of C(sp3)–C(sp2) σ-b...
Asymmetric Synthesis of (Aza)flavanones by the Evolution of CarOx Ligands
Amino-pyridine-oxazoline (NHPyOx) is conceived as an unprecedented model via the core-emulating optimization of CarOx liga...
The general method for E-selective olefination of acylsilanes with isocyanides via silver catalysis
Trisubstituted alkenes are valuable intermediates in synthetic organic chemistry. The olefination of acylsilanes is expect...
Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study
Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study
Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study
Oculomotor Findings in Videonystagmography across the Lifespan
Thieme E-Books & E-Journals
Applied Research in Clinical Audiology with Spanish Speakers in the United States: A Scoping Review
Thieme E-Books & E-Journals
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