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[Articles] Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial
SummaryBackgroundTo date, no immunological data on COVID-19 heterologous vaccination schedules in humans have been reporte...
[Comment] Tirzepatide and the new era of twincretins for diabetes
Type 2 diabetes and obesity are responsible for a large global burden of morbidity and mortality in the form of card...
[Correspondence] Addressing the real trajectory of COVID-19 in the Eastern Mediterranean region – Authors' reply
Our Correspondence1Nabeth P Hassam M Adib K Abubakar A Brennan R New COVID-19 resurgence in the WHO Eastern Mediterranean ...
[Correspondence] Benzodiazepines for the long-term treatment of anxiety disorders?
Department of Psychiatry, Monash University, Wellington Road, Clayton, Victoria, AustraliaCollege of Medicine and Public H...
[Correspondence] Surviving syndemics
In their Comment on the double burden of HIV and COVID-19 in US Black communities, Errol Fields and colleagues1Fields EL C...
[Editorial] COVID-19 in Latin America—emergency and opportunity
Latin America and the Caribbean (LAC) have been hit the hardest by the COVID-19 pandemic, with 25% of recent global infect...
[Correspondence] Addressing the real trajectory of COVID-19 in the Eastern Mediterranean region
Pierre Nabeth and colleagues1Nabeth P Hassam M Adib K Abubakar A Brennan R New COVID-19 resurgence in the WHO Eastern Medi...
[Articles] Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial
Background Despite advancements in care, many people with type 2 diabetes do not meet treatment goal...
[Correspondence] WHO COVID-19 therapeutic guidelines – Authors' reply
In response to Nicholas White and colleagues,1 we offer these clarifications. WHO guideline development methods are prespe...
[Articles] Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial
Background The PI3K/AKT and androgen-receptor pathways are dysregulated in metastatic castration-resistant ...
[Comment] The Wakley–Wu Lien Teh Prize Essay 2021: the hidden life in medicine
In 2019, The Lancet launched the Wakley–Wu Lien Teh Prize Essay in honour of physician Wu Lien Teh, who led the figh...
[Perspectives] Etheldreda Nakimuli-Mpungu: innovator in mental health
Etheldreda Nakimuli-Mpungu is a rising researcher and clinician doing innovative work in mental health and HIV in su...
[World Report] The slow road to atonement
Medicine during the Nazi period and the Shoah (Holocaust) is not a matter of the distant past. Historical evidence documen...
[Perspectives] Premonition ignored
Cholera devastated Hamburg in 1892: there were an estimated 10 000 deaths in 6 weeks. It was the only German city th...
[Correspondence] Benzodiazepines for the long-term treatment of anxiety disorders? – Authors' reply
We thank Prashant Tibrewal and colleagues for their Correspondence, in which they argue that benzodiazepines are an import...
[Obituary] Drissa Diallo
Pharmacist and authority on traditional medicine. Born in Blendio, Mali, on Jan 1, 1956, he died of a brain tumour in Abid...
[Correspondence] Surviving syndemics – Authors' reply
In a response to our Comment,1Fields EL Copeland R Hopkins E Same script, different viruses: HIV and COVID-19 in US Black ...
[Correspondence] WHO COVID-19 therapeutic guidelines
In response to Nicholas White and colleagues,1White NJ Strub-Wourgaft N Faiz A Guerin PJ Guidelines should not pool eviden...
[Correspondence] Pembrolizumab plus chemotherapy in triple-negative breast cancer – Authors' reply
We thank Jun Masuda and colleagues for their interest in the results of the KEYNOTE-355 study.1Cortes J Cescon DW Rugo HS ...
[Correspondence] Countdown on health and climate change: too important for methodological errors
Nick Watts and colleagues1Watts N Amann M Arnell N et al.The 2020 report of the Lancet Countdown on health and climate cha...
[Correspondence] Tranexamic acid for subarachnoid haemorrhage – Authors' reply
René Post and colleagues1 report that, among a cohort of 955 patients with spontaneous CT-proven subarachnoid haemorrhage,...
[Correspondence] Countdown on health and climate change: too important for methodological errors – Authors' reply
We thank Peter Morfeld and Thomas Erren for their interest in the 2020 report of the Lancet Countdown.1Watts N Amann M Arn...
[Correspondence] Pembrolizumab plus chemotherapy in triple-negative breast cancer
We read with great interest the practice-changing results of the KEYNOTE-355 trial by Javier Cortes and colleagues,1Cortes...
[Articles] Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic: an interrupted time-series analysis
SummaryBackgroundLittle evidence is available on the use of telehealth for antenatal care. In response to the COVID-19 pan...
[Articles] Body-mass index and obesity in urban and rural China: findings from consecutive nationally representative surveys during 2004–18
Background In China, mean body-mass index (BMI) and obesity in adults have increased steadily since ...
[Correspondence] Refractory cardiac arrest: when timing is crucial
SAMU de Paris, Necker University Hospital, Assistance Publique-Hôpitaux de Paris, Paris 75730, FranceINSERM U955, École Na...
[Obituary] Dinesh Mohan
Bioengineer who specialised in road safety and injury prevention and human rights activist. Born on April 4, 1945, in what...
[World Report] North Korean health at risk due to border closures
Most links to North Korea have been cut for 18 months, severely limiting imports of food and vital medicines. Sharmi...
[World Report] Levelling up health in the UK
The UK has plans to “level up” opportunities for people and communities across the country. But will this improve he...
[Perspectives] Sparks through the stubble: dying in a pandemic
In December, 1993, 4 months before his death from AIDS-related complications, the author and director Derek Jarman r...
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