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Complex roles of autophagy in cancer development, immune evasion, and drug resistance
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Modeling the epidemiologic impact of age-targeted vaccination for drug-resistant tuberculosis
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Zebrafish patient-derived xenograft system for predicting carboplatin resistance and metastasis of ovarian cancer
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Revolutionising infection control: building the next generation of phage banks
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TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4
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Fasting-mimicking diet potentiates anti-tumor effects of CDK4/6 inhibitors against breast cancer by suppressing NRAS- and IGF1-mediated mTORC1 signaling
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Targeting NQO1 induces ferroptosis and triggers anti-tumor immunity in immunotherapy-resistant KEAP1-deficient cancers
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Comprehensive metabolomic analysis identifies key biomarkers and modulators of immunotherapy response in NSCLC patients
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Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation
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Widespread loss-of-function mutations implicating preexisting resistance to new or repurposed anti-tuberculosis drugs
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Novel mobile colistin resistance gene mcr-4.9 in Vibrio cholerae from migratory birds
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Prophylactic use of antibiotics – A strategy with unforeseen risks?
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E3 ubiquitin ligase DTX2 fosters ferroptosis resistance via suppressing NCOA4-mediated ferritinophagy in non-small cell lung cancer
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Breaking the Barrier: Epigenetic Strategies to Combat Platinum Resistance in Colorectal Cancer
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Emergence of novel Klebsiella pneumoniae ST types with multidrug resistance in clinic
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The important role of lactylation in regulating DNA damage repair and tumor chemotherapy resistance
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CYP1B1 Promotes PARPi-Resistance via Histone H1.4 Interaction and Increased Chromatin Accessibility in Ovarian Cancer
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O-GlcNAcylation regulation of RIPK1-dependent apoptosis dictates sensitivity to sunitinib in renal cell carcinoma
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Unraveling the secrets: Evolution of resistance mediated by membrane proteins
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Emergence of silent NDM-1 carbapenemase gene in carbapenem-susceptible Klebsiella pneumoniae: Clinical implications and epidemiological insights
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The Important Role of Lactylation in Regulating DNA Damage Repair and Tumor Chemotherapy Resistance: Findings from Two Back-to-Back Studies
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RGS5+ lymphatic endothelial cells facilitate metastasis and acquired drug resistance of breast cancer through oxidative stress-sensing mechanism
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An increased prevalence of carbapenem-resistant hypervirulent Klebsiella pneumoniae associated with the COVID-19 pandemic
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CBX4 counteracts cellular senescence to desensitize gastric cancer cells to chemotherapy by inducing YAP1 SUMOylation
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The key role of iroBCDN-lacking pLVPK-like plasmid in the evolution of the most prevalent hypervirulent carbapenem-resistant ST11-KL64 Klebsiella pneumoniae in China
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Ultrastructural, metabolic and genetic characteristics of determinants facilitating the acquisition of macrolide resistance by Streptococcus pneumoniae
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crVDAC3 alleviates ferroptosis by impeding HSPB1 ubiquitination and confers trastuzumab deruxtecan resistance in HER2-low breast cancer
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Folylpolyglutamate synthetase inactivation in relapsed ALL induces a druggable folate metabolic vulnerability
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Un-methylation of NUDT21 represses docosahexaenoic acid biosynthesis contributing to enzalutamide resistance in prostate cancer
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CRISPR-AMRtracker: A novel toolkit to monitor the antimicrobial resistance gene transfer in fecal microbiota
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