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Framework nucleic acid-based nanoparticles enhance temozolomide sensitivity in glioblastoma
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BCL7A inhibits the progression and drug-resistance in acute myeloid leukemia
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Intersecting Pathways: The Role of Hybrid E/M Cells and Circulating Tumor Cells in Cancer Metastasis and Drug Resistance
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Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases
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Point Mutation P174L of the penA Gene Endowing Ceftazidime resistance to Burkholderia pseudomallei in China
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Increased Oxygen Stimulation Promotes Chemoresistance and Phenotype Shifting through PLCB1 in Gliomas
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FAT1 as a tumor mutation burden specific gene affects the immunotherapy effect in head and neck squamous cell cancer
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Dynamic Immunoediting by Macrophages in Homologous Recombination Deficiency-Stratified Pancreatic Ductal Adenocarcinoma
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Circulating tumor cells with increasing aneuploidy predict inferior prognosis and therapeutic resistance in small cell lung cancer
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A distinct subset of urothelial cells with enhanced EMT features promotes chemotherapy resistance and cancer recurrence by increasing COL4A1-ITGB1 mediated angiogenesis
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Mechanisms of Sensitivity and Resistance to CDK4/CDK6 Inhibitors in Hormone Receptor-positive Breast Cancer Treatment
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Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane
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Cancer Plasticity in Therapy Resistance: Mechanisms and Novel Strategies
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Corrigendum to: “Circumventing drug resistance in gastric cancer: A spatial multi-omics exploration of chemo and immuno-therapeutic response dynamics” [Drug Resist Updates 74 (2024) 101080]
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Surface Chemistry Engineered Selenium Nanoparticles as Bactericidal and Immuno-modulating Dual-functional Agents for Combating Methicillin-resistant Staphylococcus aureus Infection
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LncRNA DYNLRB2-AS1 promotes gemcitabine resistance of nasopharyngeal carcinoma by inhibiting the ubiquitination degradation of DHX9 protein
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Lansoprazole (LPZ) reverses multidrug resistance (MDR) in cancer through impeding ATP-binding cassette (ABC) transporter-mediated chemotherapeutic drug efflux and lysosomal sequestration.
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Targeting Anoikis Resistance as a Strategy for Cancer Therapy
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Application of biomimetic nanovaccines in cancer immunotherapy: A useful strategy to help combat immunotherapy resistance
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CircPDIA3/miR-449a/XBP1 feedback loop curbs pyroptosis by inhibiting palmitoylation of the GSDME-C domain to induce chemoresistance of colorectal cancer
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KLF12 Interacts with TRIM27 to affect Cisplatin Resistance and Cancer Metastasis in Esophageal Squamous Cell Carcinoma by regulating L1CAM Expression
KLF12 Interacts with TRIM27 to affect Cisplatin Resistance and Cancer Metastasis in Esophageal Squamous Cell Carcinoma by regulating L1CAM Expression
Available online 27 May 2024, 101096Author links open overlay panel, , , , , , , , , , , AbstractKrüppel-like factor 12 (K...
FAT1 as a tumor mutation burden specific gene affects the immunotherapy effect in head and neck squamous cancer
FAT1 as a tumor mutation burden specific gene affects the immunotherapy effect in head and neck squamous cancer
Accounting for the sixth most common cancer, head and neck carcinoma (HNC)，90% of whom are HNSCC，is an aggressive malignan...
Characterization of NMCR-3, NMCR-4 and NMCR-5, three novel non-mobile colistin resistance determinants: implications for MCR-3, MCR-7 and MCR-5 progenitors, respectively
Characterization of NMCR-3, NMCR-4 and NMCR-5, three novel non-mobile colistin resistance determinants: implications for MCR-3, MCR-7 and MCR-5 progenitors, respectively
Colistin (polymyxin E), the last line of defense against multidrug resistant Gram-negative bacteria, was increasingly bein...
Spotlight on Ideal Target Antigens and Resistance in Antibody-Drug Conjugates: Strategies for Competitive Advancement
Spotlight on Ideal Target Antigens and Resistance in Antibody-Drug Conjugates: Strategies for Competitive Advancement
Cancer is a significant public health problem that seriously endangers human health and social development in the world (K...
Heterogeneity of SOS response expression in clinical isolates of Escherichia coli influences adaptation to antimicrobial stress
Heterogeneity of SOS response expression in clinical isolates of Escherichia coli influences adaptation to antimicrobial stress
In recent years, new evidence has shown that the SOS response plays an important role in the response to antimicrobials, w...
Potential targets and therapeutics for cancer stem cell-based therapy against drug resistance in hepatocellular carcinoma
Potential targets and therapeutics for cancer stem cell-based therapy against drug resistance in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common digestive malignancy, ranking the sixth-most prevalent cancer and the fo...
Syk-dependent homologous recombination activation promotes cancer resistance to DNA targeted therapy
Syk-dependent homologous recombination activation promotes cancer resistance to DNA targeted therapy
Cells employ a series of repair mechanisms to maintain genome integrity following exposure to endogenous or exogenous dama...
Expansion and transmission dynamics of high risk carbapenem-resistant Klebsiella pneumoniae subclones in China: An epidemiological, spatial, genomic analysis
Expansion and transmission dynamics of high risk carbapenem-resistant Klebsiella pneumoniae subclones in China: An epidemiological, spatial, genomic analysis
AimsCarbapenem-resistant Klebsiella pneumonia (CRKP) is a global threat that varies by region. The global distribution, ev...
Advances in Molecular Targeted Drugs in Combination with CAR-T Cell Therapy for Hematologic Malignancies
Advances in Molecular Targeted Drugs in Combination with CAR-T Cell Therapy for Hematologic Malignancies
Available online 26 March 2024, 101082Author links open overlay panel, , , , , , , , AbstractMolecular targeted drugs and ...
Circumventing Drug Resistance in Gastric Cancer: A Spatial Multi-omics Exploration of Chemo and Immuno-Therapeutic Response Dynamics
Circumventing Drug Resistance in Gastric Cancer: A Spatial Multi-omics Exploration of Chemo and Immuno-Therapeutic Response Dynamics
Gastric cancer (GC) is a prevalent and deadly disease, ranking as the fifth most common cancer and the third leading cause...
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