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Interaction of Albumin with Angiotensin-I-Converting Enzyme According to Molecular Modeling Data
Interaction of Albumin with Angiotensin-I-Converting Enzyme According to Molecular Modeling Data
Human serum albumin (HSA) is an endogenous inhibitor of angiotensin-I-converting enzyme (ACE), which is an integral membra...
Simulation of the Glycolytic Metabolite Concentration Profile in Mammalian Resting Skeletal Muscles
Simulation of the Glycolytic Metabolite Concentration Profile in Mammalian Resting Skeletal Muscles
A mathematical model of glycolysis in mammalian skeletal muscles is presented for the first time, in which stationary conc...
Cationic and Ionizable Amphiphiles Based on Dihexadecyl Ester of L-Glutamic Acid for Liposomal Transport of RNA
Cationic and Ionizable Amphiphiles Based on Dihexadecyl Ester of L-Glutamic Acid for Liposomal Transport of RNA
Various RNAs are among the most promising and actively developed therapeutic agents for the treatment of tumors, infectiou...
Oxygenic Photosynthesis: Induction of Chlorophyll a Fluorescence and Regulation of Electron Transport in Thylakoid Membranes In Silico
Oxygenic Photosynthesis: Induction of Chlorophyll a Fluorescence and Regulation of Electron Transport in Thylakoid Membranes In Silico
The paper describes an extended mathematical model for the regulation of the key stages of electron transfer in the photos...
Electrostatic Potentials during Adsorption and Photochemical Reactions of Pyranine on Bilayer Lipid Membranes
Electrostatic Potentials during Adsorption and Photochemical Reactions of Pyranine on Bilayer Lipid Membranes
Adsorption and photochemical reactions of pyranine on a bilayer lipid membrane (BLM) have been studied by measuring electr...
Approach for Analysis of Intracellular Markers in Phosphatidylserine-Positive Platelets
Approach for Analysis of Intracellular Markers in Phosphatidylserine-Positive Platelets
Phosphatidylserine- (PS-) positive platelets play an important role in thrombosis and hemostasis. They have high procoagul...
Comparison of Spontaneous and Evoked Activity of CA1 Pyramidal Cells and Dentate Gyrus Granule Cells of the Hippocampus at an Increased Extracellular Potassium Concentration
Comparison of Spontaneous and Evoked Activity of CA1 Pyramidal Cells and Dentate Gyrus Granule Cells of the Hippocampus at an Increased Extracellular Potassium Concentration
In this work the effect of changing extracellular potassium concentration ([K+]o) on spontaneous and evoked burst activity...
Structural Studies of Ion Channels: Achievements, Problems, and Perspectives
Structural Studies of Ion Channels: Achievements, Problems, and Perspectives
The superfamily of membrane proteins known as P-loop channels encompasses potassium, sodium, and calcium channels, as well...
Lipid-Mediated Adaptation of Proteins and Peptides in Cell Membranes
Lipid-Mediated Adaptation of Proteins and Peptides in Cell Membranes
The paper overviews the results of computational studies of the molecular mechanisms underlying the adaptation of model ce...
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Neurodegenerative diseases, along with cardiovascular and oncological pathologies, are one of the most acute problems of m...
Mechanisms of Lipid-Mediated Regulation of the Pore-Forming Activity of Antimicrobial Agents: Studies on Planar Lipid Bilayers
Mechanisms of Lipid-Mediated Regulation of the Pore-Forming Activity of Antimicrobial Agents: Studies on Planar Lipid Bilayers
Planar lipid bilayers are unique tools designed for modeling cell membranes and electrophysiological studies of ion channe...
Structure and Functions of the OTOP1 Proton Channel
Structure and Functions of the OTOP1 Proton Channel
OTOP1 belongs to the otopetrin family of membrane proteins that form proton channels in cells of diverse types. In mammals...
Evolutionary Choice between Cholesterol and Ergosterol
Evolutionary Choice between Cholesterol and Ergosterol
Sterol biosynthesis has evolved early in the history of eukaryotes. In most animals, as well as in primitive fungi, the ma...
Membrane-Dependent Reactions of Blood Coagulation: Classical View and State-of-the-Art Concepts
Membrane-Dependent Reactions of Blood Coagulation: Classical View and State-of-the-Art Concepts
The complex mechanism called hemostasis evolved in living organisms to prevent blood loss when a blood vessel is damaged. ...
Cell Membrane Cholesterol and Regulation of Cellular Processes: New and the Same Old Thing
Cell Membrane Cholesterol and Regulation of Cellular Processes: New and the Same Old Thing
Membranes of living cells, or biological membranes, are unique molecular systems in which the functioning of all molecules...
Role of Membrane H+ Transport and Plasmalemma Excitability in Pattern Formation, Long-Distance Transport and Photosynthesis of Characean Algae
Role of Membrane H+ Transport and Plasmalemma Excitability in Pattern Formation, Long-Distance Transport and Photosynthesis of Characean Algae
Illuminated giant cells of Characeae produce alternating areas with H+-pump activity and zones of high H+/OH– conduc...
Influence of Low-Intensive He-Ne Laser Radiation on the Composition and Content of Phospholipids and Sterols in the Callus Tissues of Wheat Тriticum aestivum L.
Influence of Low-Intensive He-Ne Laser Radiation on the Composition and Content of Phospholipids and Sterols in the Callus Tissues of Wheat Тriticum aestivum L.
The effect of He-Ne laser radiation on the composition and content of cell membrane components, namely phospholipids (PL) ...
Physicochemical Features of Thrombin Binding to Platelet Membrane
Physicochemical Features of Thrombin Binding to Platelet Membrane
Thrombin is a key enzyme of the blood coagulation system, which has been actively studied since the beginning of the last ...
Comparative Investigation of the Mechanisms of Calcium Response in Human and Murine Spermatozoa
Comparative Investigation of the Mechanisms of Calcium Response in Human and Murine Spermatozoa
Calcium signaling is a principal method of signal transduction in cells of non-excitable tissues. In both mouse and human ...
Changes in Histone Code Regulation during the Initiation of Paraptosis-Like Death of HEp-2 Tumor Cells by Oxidized Disulfiram Derivatives
Changes in Histone Code Regulation during the Initiation of Paraptosis-Like Death of HEp-2 Tumor Cells by Oxidized Disulfiram Derivatives
Disulfiram (DSF) and its oxidized derivatives (DSFoxy) are currently being investigated as potential anticancer agents. We...
The Effect of 20-Hydroxyecdysone on the Functioning of Isolated Mouse Skeletal Muscle Mitochondria
The Effect of 20-Hydroxyecdysone on the Functioning of Isolated Mouse Skeletal Muscle Mitochondria
In this work we have studied the effect of the phytoecdysteroid 20-hydroxyecdysone (20E) on the functioning of mouse skele...
Electrophysiology of the Danio rerio Heart
Electrophysiology of the Danio rerio Heart
Tropical teleost fish Danio rerio is increasingly used as a model object for electrophysiological studies of human cardiac...
On the Feasibility of Using an Acedan-Based Fluorescent Probe to Monitor Hydrogen Sulfide in Primary Neuronal Cultures
On the Feasibility of Using an Acedan-Based Fluorescent Probe to Monitor Hydrogen Sulfide in Primary Neuronal Cultures
Hydrogen sulfide (H2S), which under physiological conditions exists in cells mainly in the form of the HS– anion, is...
The Mechanism of Calcium-Activated Chloride ANO6 Channel Inhibition by CaCCinh-A01
The Mechanism of Calcium-Activated Chloride ANO6 Channel Inhibition by CaCCinh-A01
Proteins of the anoctamine family (ANO) form calcium-activated chloride channels (CaCC) and phospholipid scramblases. The ...
Analysis of Molecular Mechanisms of Chronic Irradiation Effects on Electrical Signals in Wheat Plants
Analysis of Molecular Mechanisms of Chronic Irradiation Effects on Electrical Signals in Wheat Plants
The effect of ionizing radiation (IR) on plants is mainly realized by altering the status of signaling systems and modifyi...
The Effect of Nicotine Acetylcholine Receptor Ligands on the Adhesive Properties of Murine Bone Marrow Granulocytes in Inflammation
The Effect of Nicotine Acetylcholine Receptor Ligands on the Adhesive Properties of Murine Bone Marrow Granulocytes in Inflammation
Attachment to the vascular endothelium is the first step of the release of mature neutrophil granulocytes from the bone ma...
Corneal Endothelial Cell Volume Regulation Disorders in Keratoconus
Corneal Endothelial Cell Volume Regulation Disorders in Keratoconus
The study of the permeability to water and urea of plasma membranes of endothelial cells of the normal cornea and cornea w...
Energy Barrier of a Monolayer Stalk Formation during Lipid Droplet Fusion
Energy Barrier of a Monolayer Stalk Formation during Lipid Droplet Fusion
Lipid droplets are organelles responsible for the accumulation and breakdown of neutral fats in the human body. Lipid drop...
Organization of the Reserve Pool of Synaptic Vesicles in Nerve Terminals Lacking Protein Liquid Phase Components
Organization of the Reserve Pool of Synaptic Vesicles in Nerve Terminals Lacking Protein Liquid Phase Components
The protein endophilin A, which in the mammalian genome is encoded by three genes, endophilin A1, A2, and A3, regulates th...
Corrections to the Electrical Capacitance of Deformed Lipid Membrane
Corrections to the Electrical Capacitance of Deformed Lipid Membrane
The thickness of the lipid membrane is its substantial characteristics. Usually, the thickness of a lipid bilayer is exper...
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