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Flow simulations of rectal evacuation: towards a quantitative evaluation from video defaecography
Flow simulations of rectal evacuation: towards a quantitative evaluation from video defaecography
Mechanistic understanding of anorectal (patho)physiology is missing to improve the medical care of patients suffering from...
The role of biofilm matrix composition in controlling colony expansion and morphology
The role of biofilm matrix composition in controlling colony expansion and morphology
Biofilms are biological viscoelastic gels composed of bacterial cells embedded in a self-secreted polymeric extracellular ...
Experimental challenges in determining the rheological properties of bacterial biofilms
Experimental challenges in determining the rheological properties of bacterial biofilms
Bacterial biofilms are communities living in a matrix consisting of self-produced, hydrated extracellular polymeric substa...
Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media
Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media
The dynamics of blood flow in the smallest vessels and passages of the human body, where the cellular character of blood b...
Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes: in vitro and in vivo
Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes: in vitro and in vivo
In eukaryotes, intracellular physico-chemical properties like macromolecular crowding and cytoplasmic viscoelasticity infl...
Frustrated ‘run and tumble’ of swimming Escherichia coli bacteria in nematic liquid crystals
Frustrated ‘run and tumble’ of swimming Escherichia coli bacteria in nematic liquid crystals
In many situations, bacteria move in complex environments, as soils, oceans or the human gut-track, where carrier fluids s...
Mucus from human bronchial epithelial cultures: rheology and adhesion across length scales
Mucus from human bronchial epithelial cultures: rheology and adhesion across length scales
Mucus is a viscoelastic aqueous fluid that participates in the protective barrier of many mammals' epithelia. In the airwa...
Hyperelastic continuum models for isotropic athermal fibrous networks
Hyperelastic continuum models for isotropic athermal fibrous networks
Many biological materials contain fibrous protein networks as their main structural components. Understanding the mechanic...
How dynamic prestress governs the shape of living systems, from the subcellular to tissue scale
How dynamic prestress governs the shape of living systems, from the subcellular to tissue scale
Cells and tissues change shape both to carry out their function and during pathology. In most cases, these deformations ar...
Semen rheology and its relation to male infertility
Semen rheology and its relation to male infertility
Infertility affects 15% of couples of reproductive age worldwide. In spite of many advances in understanding and treating ...
Potential of stem cell seeded three-dimensional scaffold for regeneration of full-thickness skin wounds
Potential of stem cell seeded three-dimensional scaffold for regeneration of full-thickness skin wounds
Hypoxic wounds are tough to heal and are associated with chronicity, causing major healthcare burden. Available treatment ...
Mathematical modelling of oxygen transport in a muscle-on-chip device
Mathematical modelling of oxygen transport in a muscle-on-chip device
Muscle-on-chip devices aim to recapitulate the physiological characteristics of in vivo muscle tissue and so maintaining l...
In vitro and in silico approaches to engineering three-dimensional biological tissues and organoids
In vitro and in silico approaches to engineering three-dimensional biological tissues and organoids
© 2022 The Authors.Published by the Royal Society under the terms of the Creative Commons Attribution License ...
Current strategies with implementation of three-dimensional cell culture: the challenge of quantification
Current strategies with implementation of three-dimensional cell culture: the challenge of quantification
From growing cells in spheroids to arranging them on complex engineered scaffolds, three-dimensional cell culture protocol...
An insight into the iPSCs-derived two-dimensional culture and three-dimensional organoid models for neurodegenerative disorders
An insight into the iPSCs-derived two-dimensional culture and three-dimensional organoid models for neurodegenerative disorders
The use of induced pluripotent stem cells (iPSCs) is a promising approach when used as models to study neurodegenerative d...
Initial source of heterogeneity in a model for cell fate decision in the early mammalian embryo
Initial source of heterogeneity in a model for cell fate decision in the early mammalian embryo
During development, cells from a population of common progenitors evolve towards different fates characterized by distinct...
Time-keeping and decision-making in living cells: Part II
Time-keeping and decision-making in living cells: Part II
Jana Wolf https://orcid.org/0000-0003-3254-5868 Mathematical Modeling of Cellular Processes, Max Delbrück Center for M...
Quantitative models for building and growing fated small cell networks
Quantitative models for building and growing fated small cell networks
Small cell clusters exhibit numerous phenomena typically associated with complex systems, such as division of labour and p...
The linear framework: using graph theory to reveal the algebra and thermodynamics of biomolecular systems
The linear framework: using graph theory to reveal the algebra and thermodynamics of biomolecular systems
The linear framework uses finite, directed graphs with labelled edges to model biomolecular systems. Graph vertices repres...
Dynamical landscapes of cell fate decisions
Dynamical landscapes of cell fate decisions
The generation of cellular diversity during development involves differentiating cells transitioning between discrete cell...
Time-keeping and decision-making in the cell cycle
Time-keeping and decision-making in the cell cycle
Cell growth, DNA replication, mitosis and division are the fundamental processes by which life is passed on from one gener...
Cycle dynamics and synchronization in a coupled network of peripheral circadian clocks
Cycle dynamics and synchronization in a coupled network of peripheral circadian clocks
The intercellular interactions between peripheral circadian clocks, located in tissues and organs other than the suprachia...
Time-keeping and decision-making in living cells: Part I
Time-keeping and decision-making in living cells: Part I
To survive and reproduce, a cell must process information from its environment and its own internal state and respond acco...
Combined multiple transcriptional repression mechanisms generate ultrasensitivity and oscillations
Combined multiple transcriptional repression mechanisms generate ultrasensitivity and oscillations
Transcriptional repression can occur via various mechanisms, such as blocking, sequestration and displacement. For instanc...
Principles, mechanisms and functions of entrainment in biological oscillators
Principles, mechanisms and functions of entrainment in biological oscillators
Entrainment is a phenomenon in which two oscillators interact with each other, typically through physical or chemical mean...
Multi-synchronization and other patterns of multi-rhythmicity in oscillatory biological systems
Multi-synchronization and other patterns of multi-rhythmicity in oscillatory biological systems
While experimental and theoretical studies have established the prevalence of rhythmic behaviour at all levels of biologic...
Spread of infectious agents through the air in complex spaces
Spread of infectious agents through the air in complex spaces
The fluid mechanical processes that govern the spread of infectious agents through the air in complex spaces are reviewed ...
High attack rate in a Tong Lau house outbreak of COVID-19 with subdivided units in Hong Kong
High attack rate in a Tong Lau house outbreak of COVID-19 with subdivided units in Hong Kong
Poor housing conditions are known to be associated with infectious diseases such as high Coronavirus disease 2019 (COVID-1...