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T2T-YAO, T2T-SHUN, and more
T2T-YAO, T2T-SHUN, and more
Available online 22 September 2023Author links open overlay panel, © 2023 The Authors. Published by Elsevier B.V. and Scie...
T2T-YAO Reference Genome of Han Chinese — New Step in Advancing Precision Medicine in China
T2T-YAO Reference Genome of Han Chinese — New Step in Advancing Precision Medicine in China
Available online 22 September 2023Author links open overlay panel© 2023 The Authors. Published by Elsevier B.V. and Scienc...
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers
KeywordsNon-small cell lung cancerEpigenomicsM&MmethylCRFDNA methylation© 2023 The Authors. Published by Elsevier B.V....
Decoding Human Biology and Disease Using Single-cell Omics Technologies
Decoding Human Biology and Disease Using Single-cell Omics Technologies
Available online 20 September 2023Author links open overlay panel, , AbstractOver the past decade, advances in single-cell...
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein Complexes
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein Complexes
KeywordsHuman protein complexProtein interaction networkSARS-CoV-2 affected complexMultifunctional proteinComplex identifi...
The First Crested Duck Genome Reveals Clues to Genetic Compensation and Crest Cushion Formation
The First Crested Duck Genome Reveals Clues to Genetic Compensation and Crest Cushion Formation
KeywordsGenetic compensationGenome assemblyChinese crested duckCrest cushionGenome adaptive evolutionData availabilityThe ...
Comprehensive Characterization and Global Transcriptome Analyses of Human Fetal Liver Terminal Erythropoiesis
Comprehensive Characterization and Global Transcriptome Analyses of Human Fetal Liver Terminal Erythropoiesis
KeywordsHuman fetal liverTerminal erythropoiesisTranscriptomeImmortalized erythroid cell lineEnucleationData availabilityT...
NetGO 3.0: A Protein Language Model Improves Large-scale Functional Annotations
NetGO 3.0: A Protein Language Model Improves Large-scale Functional Annotations
Protein function predictionWeb serviceProtein language modelLearning to rankLarge-scale multi-label learning© 2023 The Aut...
T2T-YAO: A Telomere-to-telomere Assembled Diploid Reference Genome for Han Chinese
T2T-YAO: A Telomere-to-telomere Assembled Diploid Reference Genome for Han Chinese
KeywordsReference genomeTelomere-to-telomere assemblyHan ChineseHaplotype-resolved assemblyDiploidData availabilityThe raw...
Differential Transcriptomic Landscapes of SARS-CoV-2 Variants in Multiple Organs from Infected Rhesus Macaques
Raw RNA-seq data have been deposited in the Genome Sequence Archive [86] at National Genomics Data Center, Beijing Institu...
inMTSCCA: An Integrated Multi-task Sparse Canonical Correlation Analysis for Multi-omic Brain Imaging Genetics
Brain imaging geneticsMulti-omic endophenotypeCross-endophenotype associationGenetic risk factorMedical image analysis© 20...
AB-Gen: Antibody Library Design with Generative Pre-trained Transformer and Deep Reinforcement Learning
Protein designTransformerReinforcement learningGenerative modelingMulti-objective optimization© 2023 Published by Elsevier...
Revolutionizing Antibody Discovery: An Innovative AI Model for Generating Robust Libraries
Available online 22 June 2023Author links open overlay panel, © 2023 Published by Elsevier B.V. and Science Press on behal...
Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons
KeywordsMorphineRhesus monkeyChromatin spatial architectureTopologically associated domainLoopData availabilityThe raw seq...
Recent Advances in Assembly of Plant Complex Genomes
Plant complex genomeAssembly algorithmsTelomere-to-telomere genomeHaplotype-resolved assemblySequencing technology© 2023 T...
Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants
The data supporting the results of this study can be found in the manuscript and its supplementary information files. Raw ...
Novel Time-dependent Multi-omics Integration in Sepsis-associated Liver Dysfunction
KeywordsMulti-omicsOmics technologySepsis-associated liver dysfunctionSingle omicsTime-dependent integrationData availabil...
Omics Views of Mechanisms for Cell Fate Determination in Early Mammalian Development
Cell fate determinationCellular heterogeneityCell polaritySingle-cell omicsMammalian preimplantation embryos© 2023 The Aut...
NetGO 3.0: Protein Language Model Improves Large-scale Functional Annotations
KeywordsProtein function predictionWeb serviceProtein language modelsLearning to rankLarge-scale multi-label learningData ...
Protein Structure Prediction: Challenges, Advances, and the Shift of Research Paradigms
Protein foldingProtein structure predictionDeep learningTransformerLanguage model© 2023 The Authors. Published by Elsevier...
Multi-omics of Circular RNAs and Their Responses to Hormones in Moso Bamboo (Phyllostachys edulis)
Raw sequencing data from mRNA sequencing, circRNA sequencing, degradome sequencing, and small RNA sequencing are available...
Patient Assessment and Therapy Planning Based on Homologous Recombination Repair Deficiency
DNA damage responseHomologous recombination repair deficiencyPoly (ADP-ribose) polymerase inhibitorBiomarkerHarmonization©...
RNA Methylome Reveals the m6A-mediated Regulation of Flavor Metabolites in Tea Leaves under Solar-withering
The raw sequencing data have been deposited in the Genome Sequence Archive [75] at National Genomics Data Center, Beijing ...
VIS Atlas: A Database of Virus Integration Sites in Human Genome from NGS Data to Explore Integration Patterns
Available online 16 February 2023Author links open overlay panel, , , , , , , , , , , , , , , AbstractIntegration of oncog...
Preclinical-to-clinical Anti-cancer Drug Response Prediction and Biomarker Identification Using TINDL
KeywordsDrug responseDeep learningExplainable AICancerGene knockdown experimentData availabilityAn implementation of TINDL...
Identifying RNA Modifications by Direct RNA Sequencing Reveals Complexity of Epitranscriptomic Dynamics in Rice
KeywordsDirect RNA resequencingPolyadenylated transcriptomeN6-methyladenosineN5-methylcytosineRiceData availabilityThe raw...
Whole-genome Duplication Reshaped Adaptive Evolution in A Relict Plant Species, Cyclocarya paliurus
The whole genome sequencing raw data including Illumina short reads, PacBio long reads, Hi-C interaction reads, and transc...
What Has Genomics Taught An Evolutionary Biologist?
Available online 28 January 2023Author links open overlay panelAbstractGenomics, an interdisciplinary field of biology on ...
The Integrative Studies on the Functional A-to-I RNA Editing Events in Human Cancers
All the analysis results involved in this study were available at https://ccsm.uth.edu/CAeditome/.The results here are in ...
Mapping Multiple Factors-mediated Chromatin Interactions to Assess Dysregulation of Lung Cancer-related Genes
Sequence data generated in this study have been deposited in the Genome Sequence Archive [65] at National Genomics Data Ce...
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