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Harnessing immunological targets for COVID-19 immunotherapy
COVID-19 is an infectious and highly contagious disease caused by SARS-CoV-2. The immunotherapy strategy has a great poten...
Parvovirus B19 affects thrombopoietin and IL-11 gene expression in human bone marrow mesenchymal stem cells
Aim: Human bone marrow mesenchymal stem cells (hBMSCs) may be infected by parvovirus B19 (B19V). hBMSCs support bone marro...
The role of Epstein–Barr virus-encoded latent membrane proteins in host immune escape
Epstein–Barr virus (EBV) is a type IV herpesvirus that widely infects the vast majority of adults, and establishes a laten...
Independent and incremental prognostic value of D-dimer in hospitalized COVID-19 patients
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial intere...
Patient-reported outcomes for HIV: the future of long-acting injectables and antiretroviral therapy evaluations
Patient-reported outcomes (PROs) are an increasingly important aspect of patient care, as they offer a perspective from th...
A survey on prevalence, risk factors and knowledge for oral human papillomavirus infections among university students
Aim: This study analyses the prevalence, risk factors and knowledge levels for oral human papillomavirus (HPV) infection i...
Potential drugs against COVID-19 revealed by gene expression profile, molecular docking and molecular dynamic simulation
Aim: SARS-CoV-2, an emerging betacoronavirus, is the causative agent of COVID-19. Currently, there are few specific and se...
An overview of sex hormones in relation to SARS-CoV-2 infection
Aim: Sex differences in COVID-19 outcomes might be explained from a sex hormones (SexHs) perspective. Materials & meth...
In silico discovery of SARS-CoV-2 main protease inhibitors from the carboline and quinoline database
Aim: SARS-CoV-2 caused more than 3.8 million deaths according to the WHO. In this urgent circumstance, we aimed at screeni...
Targeting SARS-CoV-2 nonstructural protein 15 endoribonuclease: an in silico perspective
The newly emerged human coronavirus, SARS-CoV-2, had begun to spread last year and sparked worldwide. In this study, molec...
Reappraisal of trifluperidol against Nsp3 as a potential therapeutic for novel COVID-19: a molecular docking and dynamics study
Novel COVID-19 is a highly infectious disease that is caused by the recently discovered SARS-CoV-2. It is a fast-spreading...
Association of anemia and COVID-19 in hospitalized patients
Aim: COVID-19 is a major threat to public health worldwide. A large proportion of COVID-19 patients is proved to develop a...
A survey on prevalence, risk factors and knowledge for oral human papilloma virus infections among university students
Aim: This study analyses the prevalence, risk factors and knowledge levels for oral human papilloma virus (HPV) infection ...
Safety, efficacy and acceptability of SARS-CoV-2 vaccines in patients with cancer
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial intere...
shRNA targeting nonstructural protein inhibits the replication of severe fever with thrombocytopenia syndrome virus
Aim: To explore whether shRNA targeting nonstructural protein (NSs) of severe fever with thrombocytopenia syndrome virus (...
Elimination of hepatitis C among HIV-positive population in Asia: old and new challenges
Hepatitis C virus (HCV) prevalence is high among people living with HIV co-infected with HCV, people who inject drugs, men...
The COVID-19 pandemic: an increased risk of rheumatoid arthritis
COVID-19 is a respiratory infection similar to viral pneumonia and is caused by SARS-CoV-2. Chloroquine and hydroxychloroq...
V483A: an emerging mutation hotspot of SARS-CoV-2
One of the many mutations that have occurred in the viral genome is the V483A mutation, which is a part of the receptor-bi...
Natural selection on synonymous mutations in SARS-CoV-2 and the impact on estimating divergence time
Tweetable abstract To adapt to human host environment, synonymous mutations in SARS-CoV-2 are shaped by tRNA selection, en...
SARS-CoV-2 likely targets cellular PDZ proteins: a common tactic of pathogenic viruses
AP Rice and JT Kimata received support for COVID-19 research from a Baylor College of Medicine Pilot Project Award. The au...
Tocilizumab in the treatment of coronavirus disease 2019 pneumonia: real-world data from a case series
Aim: Coronavirus disease 2019 is a life-threatening disease and how to improve survival of the patients is of great import...
Low frequency of human cytomegalovirus in cancerous and precancerous cervical samples of Iranian women
Background: HPV-16 has a significant role in cervical cancers; co-infection with human cytomegalovirus (HCMV) as an oncomo...
Seroprevalence of the hepatitis E virus antibodies among blood donors in the Qassim region, Saudi Arabia
Aim: Hepatitis E virus (HEV) transmission through blood transfusion is a major public health issue worldwide. We aimed to ...
Druggability of cavity pockets within SARS-CoV-2 spike glycoprotein and pharmacophore-based drug discovery
Aim: Virus spike glycoprotein of SARS-CoV-2 is a good target for drug discovery. Objective: To examine the potential for d...