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Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients
Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients
Calprotectin (S100A8/A9) is a pro-inflammatory mediator primarily released from neutrophils. Previous studies have reveale...
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study
Fluid resuscitation is fundamental in acute pancreatitis (AP) treatment. However, the optimal choice between normal saline...
Determining prognostic indicator for anticoagulant therapy in sepsis-induced disseminated intravascular coagulation
Determining prognostic indicator for anticoagulant therapy in sepsis-induced disseminated intravascular coagulation
There is no reliable indicator that can assess the treatment effect of anticoagulant therapy for sepsis-associated dissemi...
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients
Difficult-to-wean patients, typically identified as those failing the initial spontaneous breathing trial (SBT), face elev...
Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study
Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study
In out-of-hospital cardiac arrest (OHCA) patients with extracorporeal cardiopulmonary resuscitation (ECPR), the associatio...
Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation
Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation
Patients who receive invasive mechanical ventilation (IMV) in the intensive care unit (ICU) have exhibited lower in-hospit...
Case volume and specialization in critically ill emergency patients: a nationwide cohort study in Japanese ICUs
Case volume and specialization in critically ill emergency patients: a nationwide cohort study in Japanese ICUs
Previous studies have explored the association between the number of cases and patient outcomes for critical illnesses suc...
Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling
Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling
To optimize right ventricular–pulmonary coupling during veno-arterial (VA) ECMO weaning, inotropes, vasopressors and...
Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients
Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients
Recent advances on cardiorespiratory monitoring applied in ARDS patients undergoing invasive mechanical ventilation and no...
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium
Extracorporeal membrane oxygenation (ECMO) is a rescue therapy in patients with severe acute respiratory distress syndrome...
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis
The prognostic nutritional index (PNI), integrating nutrition and inflammation markers, has been increasingly recognized a...
Respiratory drive: a journey from health to disease
Respiratory drive: a journey from health to disease
Respiratory drive is defined as the intensity of respiratory centers output during the breath and is primarily affected by...
Predictors and outcomes of withholding and withdrawal of life-sustaining treatments in intensive care units in Singapore: a multicentre observational study
Predictors and outcomes of withholding and withdrawal of life-sustaining treatments in intensive care units in Singapore: a multicentre observational study
Clinical practice guidelines on limitation of life-sustaining treatments (LST) in the intensive care unit (ICU), in the fo...
Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial
Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial
Arterial catheters (ACs) are critical for haemodynamic monitoring and blood sampling but are prone to complications. We in...
From bedside to recovery: exercise therapy for prevention of post-intensive care syndrome
From bedside to recovery: exercise therapy for prevention of post-intensive care syndrome
As advancements in critical care medicine continue to improve Intensive Care Unit (ICU) survival rates, clinical and resea...
Unit-to-unit transfer due to shortage of intensive care beds in Sweden 2015–2019 was associated with a lower risk of death but a longer intensive care stay compared to no transfer: a registry study
Unit-to-unit transfer due to shortage of intensive care beds in Sweden 2015–2019 was associated with a lower risk of death but a longer intensive care stay compared to no transfer: a registry study
Intensive care unit-to-unit transfer due to temporary shortage of beds is increasing in Sweden. Transportation induces pra...
Exploring the therapeutic role of early heparin administration in ARDS management: a MIMIC-IV database analysis
Exploring the therapeutic role of early heparin administration in ARDS management: a MIMIC-IV database analysis
Acute respiratory distress syndrome (ARDS) is a severe respiratory condition characterized by a high mortality rate, the m...
Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study
Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study
Patients with sepsis-associated encephalopathy (SAE) have higher mortality rates and longer ICU stays. Predictors of SAE a...
External validation of the HACOR score and ROX index for predicting treatment failure in patients with coronavirus disease 2019 pneumonia managed on high-flow nasal cannula therapy: a multicenter retrospective observational study in Japan
External validation of the HACOR score and ROX index for predicting treatment failure in patients with coronavirus disease 2019 pneumonia managed on high-flow nasal cannula therapy: a multicenter retrospective observational study in Japan
The HACOR score for predicting treatment failure includes vital signs and acid–base balance factors, whereas the ROX...
Association between regional critical care capacity and the incidence of invasive mechanical ventilation for coronavirus disease 2019: a population-based cohort study
Association between regional critical care capacity and the incidence of invasive mechanical ventilation for coronavirus disease 2019: a population-based cohort study
Coronavirus disease 2019 (COVID-19) has exposed critical care supply shortages worldwide. This study aimed to investigate ...
Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry
Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry
Chest computed tomography findings are helpful for understanding the pathophysiology of severe acute respiratory distress ...
Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis
Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis
Our previous study in 2011 concluded that permissive underfeeding may improve outcomes in patients receiving parenteral nu...
Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive
Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive
The limitation of life sustaining treatments (LLST) causes ethical dilemmas even in patients faced with poor prognosis, wh...
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review
Post-intensive care syndrome (PICS) is the long-lasting impairment of physical functions, cognitive functions, and mental ...
Development of quality indicators for palliative care in intensive care units and pilot testing them via electronic medical record review
Development of quality indicators for palliative care in intensive care units and pilot testing them via electronic medical record review
Patients in intensive care units (ICUs) often require quality palliative care for relief from various types of suffering. ...
Mechanical circulatory support in cardiogenic shock
Mechanical circulatory support in cardiogenic shock
Cardiogenic shock is a complex and diverse pathological condition characterized by reduced myocardial contractility. The g...
Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort
Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort
Extra-hepatic vitamin K-status, measured by dephosphorylated uncarboxylated matrix Gla protein (dp-ucMGP), maintains vascu...
Functional intervention following cardiac surgery to prevent postoperative delirium in older patients (FEEL WELL study)
Functional intervention following cardiac surgery to prevent postoperative delirium in older patients (FEEL WELL study)
Postoperative delirium is a common complication in patients after cardiac surgery, especially in older patients, and can m...
Light and dark sides of evidence-based and supportive ICU care for patients undergoing extracorporeal membrane oxygenation
Light and dark sides of evidence-based and supportive ICU care for patients undergoing extracorporeal membrane oxygenation
Authors and AffiliationsNon-Profit Organization ICU Collaboration Network (ICON), 2-15-13 Hongo, Bunkyo-Ku, Tokyo, 113-003...
Intensive care unit mortality and cost-effectiveness associated with intensivist staffing: a Japanese nationwide observational study
Intensive care unit mortality and cost-effectiveness associated with intensivist staffing: a Japanese nationwide observational study
Japan has four types of intensive care units (ICUs) that are divided into two categories according to the management fee c...
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