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Statin use and long-term risk of recurrent intracerebral haemorrhage: the MUCH-Italy
Statin use and long-term risk of recurrent intracerebral haemorrhage: the MUCH-Italy
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The relationship between corticospinal excitability and structural integrity in stroke patients
The relationship between corticospinal excitability and structural integrity in stroke patients
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Intermediate HTT CAG repeats worsen disease severity in amyotrophic lateral sclerosis
Intermediate HTT CAG repeats worsen disease severity in amyotrophic lateral sclerosis
IntroductionRecent research has indicated a connection between amyotrophic lateral sclerosis (ALS) and Huntington’s diseas...
Paternal exposure to antiseizure medications and offspring outcomes
Paternal exposure to antiseizure medications and offspring outcomes
Is there evidence to support restrictions in the use of valproate in male patients? This issue is addressed in a JNNP syst...
Predictors of outcome in cNORSE: hope for tomorrow
Predictors of outcome in cNORSE: hope for tomorrow
Caring for a patient with a diagnosis of cryptogenic new-onset refractory status epilepticus (cNORSE) is one of the most c...
First-ever seizure and eligibility for commercial motor vehicle driving
First-ever seizure and eligibility for commercial motor vehicle driving
WHAT IS ALREADY KNOWN ON THIS TOPICAfter a first-ever seizure, a return to driving a commercial vehicle may be considered ...
Sodium valproate is associated with cortical thinning of disease-specific areas in juvenile myoclonic epilepsy
Sodium valproate is associated with cortical thinning of disease-specific areas in juvenile myoclonic epilepsy
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Paternal exposure to antiseizure medications and offspring outcomes: a systematic review
Paternal exposure to antiseizure medications and offspring outcomes: a systematic review
IntroductionThe teratogenic effects of antiseizure medications (ASMs) taken by mothers are well-documented.1 In contrast, ...
Novel therapies in CIDP
Novel therapies in CIDP
Immunoglobulin, steroids and plasma exchange (PLEX) are proven effective therapies in provoking and sustaining remission i...
Prognosis prediction and immunotherapy optimisation for cryptogenic new-onset refractory status epilepticus
Prognosis prediction and immunotherapy optimisation for cryptogenic new-onset refractory status epilepticus
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CSF sphingolipids are correlated with neuroinflammatory cytokines and differentiate neuromyelitis optica spectrum disorder from multiple sclerosis
CSF sphingolipids are correlated with neuroinflammatory cytokines and differentiate neuromyelitis optica spectrum disorder from multiple sclerosis
IntroductionMultiple sclerosis (MS) diagnosis relies on a combination of clinical presentation and the presence of white m...
Phenotypic spectrum of myelin protein zero-related neuropathies: a large cohort study from five mutation clusters across Italy
Phenotypic spectrum of myelin protein zero-related neuropathies: a large cohort study from five mutation clusters across Italy
WHAT IS ALREADY KNOWN ON THIS TOPICPrevious studies acknowledged the wide phenotypic variability, explained by different p...
Visuospatial dysfunction predicts dementia-first phenoconversion in isolated REM sleep behaviour disorder
Visuospatial dysfunction predicts dementia-first phenoconversion in isolated REM sleep behaviour disorder
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Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease
Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease
AbstractBackground Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently described demyeli...
Clinical, prognostic and pathophysiological implications of MOG-IgG detection in the CSF: the importance of intrathecal MOG-IgG synthesis
Clinical, prognostic and pathophysiological implications of MOG-IgG detection in the CSF: the importance of intrathecal MOG-IgG synthesis
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Immunosuppressive therapy in elderly patients with neuromyelitis optica spectrum disorder: a retrospective multicentre study
Immunosuppressive therapy in elderly patients with neuromyelitis optica spectrum disorder: a retrospective multicentre study
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Vestibular neurology for the generalist
Vestibular neurology for the generalist
This review of vestibular neurology for the general neurologist delves into the multifaceted realm of vestibular neurology...
Complete nanopore repeat sequencing of SCA27B (GAA-FGF14 ataxia) in Japanese
Complete nanopore repeat sequencing of SCA27B (GAA-FGF14 ataxia) in Japanese
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Plasma amyloid-{beta} is associated with suicidal ideation in older adults: a 15-year follow-up study
Plasma amyloid-{beta} is associated with suicidal ideation in older adults: a 15-year follow-up study
IntroductionSuicide rates in older adults surpass those of other age groups,1 making suicide a major societal problem in t...
Neurocognitive and psychiatric outcomes associated with postacute COVID-19 infection without severe medical complication: a meta-analysis
Neurocognitive and psychiatric outcomes associated with postacute COVID-19 infection without severe medical complication: a meta-analysis
IntroductionCommon neurobehavioural symptoms associated with COVID-19 include headache, ‘brain fog’, myalgia, hyposmia, ch...
Most SOD1 mutations are pathogenic, and their identification can lead to early access to treatment
Most SOD1 mutations are pathogenic, and their identification can lead to early access to treatment
ALS is a neurodegenerative disease affecting motor neurons, leading to progressive loss of bulbar and limb motor function,...
Cyclophosphamide for myasthenia gravis: a comeback?
Cyclophosphamide for myasthenia gravis: a comeback?
Myasthenia gravis (MG) treatment’s landscape has dramatically changed with the approval of novel therapeutics that can pro...
Induction cyclophosphamide with maintenance immunosuppression in high-risk myasthenia gravis: long-term follow-up and safety profile
Induction cyclophosphamide with maintenance immunosuppression in high-risk myasthenia gravis: long-term follow-up and safety profile
IntroductionMyasthenia gravis (MG) is an autoimmune disorder of the postsynaptic neuromuscular junction characterised by f...
Phase 1 study of safety and preliminary efficacy of intranasal transplantation of human neural stem cells (ANGE-S003) in Parkinsons disease
Phase 1 study of safety and preliminary efficacy of intranasal transplantation of human neural stem cells (ANGE-S003) in Parkinsons disease
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Neurophysiological features of STN LFP underlying sleep fragmentation in Parkinsons disease
Neurophysiological features of STN LFP underlying sleep fragmentation in Parkinsons disease
WHAT IS ALREADY KNOWN ON THIS TOPICBeta oscillation, which is a biomarker for rigidity and bradykinesia during awake, sign...
Data-driven sequence of cognitive decline in people with Parkinsons disease
Data-driven sequence of cognitive decline in people with Parkinsons disease
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Cognitive rehabilitation effects on grey matter volume and Go-NoGo activity in progressive multiple sclerosis: results from the CogEx trial
Cognitive rehabilitation effects on grey matter volume and Go-NoGo activity in progressive multiple sclerosis: results from the CogEx trial
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Ethnicity and deprivation negatively impact the access to disease-modifying therapy for relapsing-remitting multiple sclerosis: a retrospective, single-centre study
Ethnicity and deprivation negatively impact the access to disease-modifying therapy for relapsing-remitting multiple sclerosis: a retrospective, single-centre study
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Dynamics of synaptic damage in severe traumatic brain injury revealed by cerebrospinal fluid SNAP-25 and VILIP-1
Dynamics of synaptic damage in severe traumatic brain injury revealed by cerebrospinal fluid SNAP-25 and VILIP-1
WHAT IS ALREADY KNOWN ON THIS TOPICSynaptic damage has been demonstrated to be a consequence of primary and secondary inju...
Impact of previous treatment history and B-cell depletion treatment duration on infection risk in relapsing-remitting multiple sclerosis: a nationwide cohort study
Impact of previous treatment history and B-cell depletion treatment duration on infection risk in relapsing-remitting multiple sclerosis: a nationwide cohort study
WHAT IS ALREADY KNOWN ON THIS TOPICB-cell depleting therapy is highly effective in relapsing-remitting multiple sclerosis,...
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