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Development of orthogonal aminoacyl-tRNA synthetase mutant for incorporating a non-canonical amino acid
Development of orthogonal aminoacyl-tRNA synthetase mutant for incorporating a non-canonical amino acid
Genetic code expansion involves introducing non-canonical amino acids (ncAAs) with unique functional groups into proteins ...
Japanese encephalitis virus hijacks ER-associated degradation regulators for its replication
Japanese encephalitis virus hijacks ER-associated degradation regulators for its replication
Flaviviruses target their replication on membranous structures derived from the ER, where both viral and host proteins pla...
15N-DNA stable isotope probing reveals niche differentiation of ammonia oxidizers in paddy soils
15N-DNA stable isotope probing reveals niche differentiation of ammonia oxidizers in paddy soils
Chemoautotrophic canonical ammonia oxidizers (ammonia-oxidizing archaea (AOA) and ammonia-oxidizing bacteria (AOB)) and co...
Characterization of tryptanthrin as an antibacterial reagent inhibiting Vibrio splendidus
Characterization of tryptanthrin as an antibacterial reagent inhibiting Vibrio splendidus
Isolates of Vibrio splendidus are ubiquitously presented in various marine environments, and they can infect diverse marin...
Comparative transcriptome analysis of Fusarium graminearum challenged with distinct fungicides and functional analysis of FgICL gene
Comparative transcriptome analysis of Fusarium graminearum challenged with distinct fungicides and functional analysis of FgICL gene
Fusarium graminearum is an economically important phytopathogenic fungus. Chemical control remains the dominant approach t...
scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data
scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data
In droplet-based single-cell and single-nucleus RNA-seq assays, systematic contamination of ambient RNA molecules biases t...
Identification of the RSX interactome in a marsupial shows functional coherence with the Xist interactome during X inactivation
Identification of the RSX interactome in a marsupial shows functional coherence with the Xist interactome during X inactivation
The marsupial specific RSX lncRNA is the functional analogue of the eutherian specific XIST, which coordinates X chromosom...
In vivo rescue of genetic dilated cardiomyopathy by systemic delivery of nexilin
In vivo rescue of genetic dilated cardiomyopathy by systemic delivery of nexilin
Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure. Multiple identified mutations in nexilin (...
MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data
MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data
Advances in spatial transcriptomics provide an unprecedented opportunity to reveal the structure and function of biology s...
QTL analysis of low temperature tolerance in maize germination by SLAF-seq and BSA technique
QTL analysis of low temperature tolerance in maize germination by SLAF-seq and BSA technique
KeywordsBulked Segregant Analysis (BSA)GerminationLow temperature toleranceMaizeQTL analysisSpecific-Locus Amplified Fragm...
Tandem gene duplication selected by activation of horizontally transferred gene in bacteria
Tandem gene duplication selected by activation of horizontally transferred gene in bacteria
Horizontal gene transfer occurs frequently in bacteria, but the mechanism driving activation and optimization of the expre...
Co-utilization of carbon sources in microorganisms for the bioproduction of chemicals
Co-utilization of carbon sources in microorganisms for the bioproduction of chemicals
The fast development of metabolic engineering has enhanced the capability of microorganisms to produce value-added chemica...
The potential of Pavlovophyceae species as a source of valuable carotenoids and polyunsaturated fatty acids for human consumption
The potential of Pavlovophyceae species as a source of valuable carotenoids and polyunsaturated fatty acids for human consumption
19-HFx19’-hexanoyloxifucoxanthinACCaseAcetyl-CoA CarboxylaseATPAdenosine triphosphateBtaABetaine lipid synthase ABtaBBetai...
Development a high-sensitivity sandwich ELISA for determining antigen content of porcine circovirus type 2 vaccines
Development a high-sensitivity sandwich ELISA for determining antigen content of porcine circovirus type 2 vaccines
Porcine circovirus type 2 (PCV2) belongs to the genus Circovirus and family Circovirus, is one of the smallest DNA viruses...
Conditional knockdown of OsMLH1 to improve plant prime editing systems without disturbing fertility in rice
Conditional knockdown of OsMLH1 to improve plant prime editing systems without disturbing fertility in rice
High-efficiency prime editing (PE) is desirable for precise genome manipulation. The activity of mammalian PE systems can ...
HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data
HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data
Bulk DNA sequencing of multiple samples from the same tumor is becoming common, yet most methods to infer copy-number aber...
Diurnal control of iron responsive element containing mRNAs through iron regulatory proteins IRP1 and IRP2 is mediated by feeding rhythms
Diurnal control of iron responsive element containing mRNAs through iron regulatory proteins IRP1 and IRP2 is mediated by feeding rhythms
Cellular iron homeostasis is regulated by iron regulatory proteins (IRP1 and IRP2) that sense iron levels (and other metab...
Biologically informed NeuralODEs for genome-wide regulatory dynamics
Biologically informed NeuralODEs for genome-wide regulatory dynamics
Gene regulatory network (GRN) models that are formulated as ordinary differential equations (ODEs) can accurately explain ...
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq
Determining whether the RNA isoforms from medically relevant genes have distinct functions could facilitate direct targeti...
Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens
Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens
Single-nucleotide variants (SNVs) in key T cell genes can drive clinical pathologies and could be repurposed to improve ce...
Role of N-linked glycosylation in porcine reproductive and respiratory syndrome virus (PRRSV) infection
Role of N-linked glycosylation in porcine reproductive and respiratory syndrome virus (PRRSV) infection
Porcine reproductive and respiratory syndrome (PRRSV) is an enveloped single-stranded positive-sense RNA virus and one of ...
Establishment of a new equine embryo brain primary cell culture with long-term expansion
Establishment of a new equine embryo brain primary cell culture with long-term expansion
Virus isolation typically involves the use of cell cultures, chicken embryos, and, to a lesser extent, laboratory animals,...
Author Correction: Computational scoring and experimental evaluation of enzymes generated by neural networks
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Advancing programmable gene expression in plants using CRISPRi-based Boolean gates
Advancing programmable gene expression in plants using CRISPRi-based Boolean gates
To advance the toolset for controlling plant gene expression, we developed a CRISPR interference-based platform for the co...