SCI时时刷

search
+
Heparin-mediated PCR interference in SARS-CoV-2 assays and subsequent reversal with heparinase I
Heparin-mediated PCR interference in SARS-CoV-2 assays and subsequent reversal with heparinase I
The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in unprecedented health, social, and economic impacts globally. ...
Transcript tinkering: RNA modifications in protozoan parasites
Transcript tinkering: RNA modifications in protozoan parasites
Apicomplexan and trypanosomatid parasites have evolved a wide range of post-transcriptional processes that allow them to r...
Characterization of vitamin D3 biotransformation by the cell lysate of Actinomyces hyovaginalis CCASU-A11-2
Characterization of vitamin D3 biotransformation by the cell lysate of Actinomyces hyovaginalis CCASU-A11-2
A former work conducted in our Lab, lead to in a effective scale up of vitamin D3 bioconversion into calcitriol by Actinom...
Saccharomyces cerevisiae cellular engineering for the production of FAME biodiesel
Saccharomyces cerevisiae cellular engineering for the production of FAME biodiesel
The unsustainable and widespread utilization of fossil fuels continues to drive the rapid depletion of global supplies. Bi...
Enhancement of doxorubicin production in Streptomyces peucetius by genetic engineering and process optimization
Enhancement of doxorubicin production in Streptomyces peucetius by genetic engineering and process optimization
Doxorubicin is an important class of anthracycline antitumor antibiotics produced by Streptomyces peucetius. The doxorubic...
Matrix-assisted laser desorption/ionization mass spectrometry imaging for quorum sensing
Matrix-assisted laser desorption/ionization mass spectrometry imaging for quorum sensing
Quorum sensing (QS) is a complex communication system in bacteria, directing their response to the environment. QS is also...
Assessing the laboratory performance of AI-generated enzymes
Assessing the laboratory performance of AI-generated enzymes
A set of 20 computational metrics was evaluated to determine whether they could predict the functionality of synthetic enz...
Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening
Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening
T cell receptor (TCR) gene therapy is a potent form of cellular immunotherapy in which patient T cells are genetically eng...
Therapeutic application of circular RNA aptamers in a mouse model of psoriasis
Therapeutic application of circular RNA aptamers in a mouse model of psoriasis
Efforts to advance RNA aptamers as a new therapeutic modality have been limited by their susceptibility to degradation and...
Computational scoring and experimental evaluation of enzymes generated by neural networks
Computational scoring and experimental evaluation of enzymes generated by neural networks
In recent years, generative protein sequence models have been developed to sample novel sequences. However, predicting whe...
Author Correction: Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
These authors contributed equally: Liang Chen, Mengjia Hong, Changming Luan.Shanghai Frontiers Science Center of Genome Ed...
Author Correction: Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing
These authors contributed equally: Liang Chen, Biyun Zhu, Gaomeng Ru, Haowei Meng, Yongchang Yan.Shanghai Frontiers Scienc...
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a centr...
Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute
Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute
Cell culture media play a critical role in cell growth and propagation by providing a substrate; media components can also...
Antibody-independent surface plasmon resonance assays for influenza vaccine quality control
Antibody-independent surface plasmon resonance assays for influenza vaccine quality control
Surface plasmon resonance (SPR)-based biosensors have emerged as a powerful platform for bioprocess monitoring due to thei...
An overview of the two-component system GarR/GarS role on antibiotic production in Streptomyces coelicolor
An overview of the two-component system GarR/GarS role on antibiotic production in Streptomyces coelicolor
The Streptomyces genus comprises Gram-positive bacteria known to produce over two-thirds of the antibiotics used in medica...
Metabolic modeling of Halomonas campaniensis improves polyhydroxybutyrate production under nitrogen limitation
Metabolic modeling of Halomonas campaniensis improves polyhydroxybutyrate production under nitrogen limitation
Poly-hydroxybutyrate (PHB) is an environmentally friendly alternative for conventional fossil fuel-based plastics that is ...
Sphingomonas lacusdianchii sp. nov., an attached bacterium inhibited by metabolites from its symbiotic cyanobacterium
Sphingomonas lacusdianchii sp. nov., an attached bacterium inhibited by metabolites from its symbiotic cyanobacterium
An alpha-proteobacterial strain JXJ CY 53 T was isolated from the cyanosphere of Microcystis sp. FACHB-905 (MF-90...
Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types
Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types
Aquaporin-1 (Aqp1), a water channel, has garnered significant interest for cell-based medicine and in vivo synthetic biolo...
Promoting osteogenesis and bone regeneration employing icariin-loaded nanoplatforms
Promoting osteogenesis and bone regeneration employing icariin-loaded nanoplatforms
There is an increasing demand for innovative strategies that effectively promote osteogenesis and enhance bone regeneratio...
Optimization strategies for CO2 biological fixation
Optimization strategies for CO2 biological fixation
The “greenhouse effect” gradually intensifies as many greenhouse gases are released. The United Nations Secretary-General ...
Deepening genomic sequences of 1081 Gossypium hirsutum accessions reveals novel SNPs and haplotypes relevant for practical breeding utility
Deepening genomic sequences of 1081 Gossypium hirsutum accessions reveals novel SNPs and haplotypes relevant for practical breeding utility
Fiber quality is a major breeding goal in cotton, but phenotypically direct selection is often hindered. In this study, we...
Agrochemical-free genetically modified and genome-edited crops – towards a ‘greener’ green revolution and achieving the United Nation’s Sustainable Development Goals
Agrochemical-free genetically modified and genome-edited crops – towards a ‘greener’ green revolution and achieving the United Nation’s Sustainable Development Goals
Agriculture has developed in the past three centuries through the following main phases: a) the 19th century organic or in...
Withania somnifera (L.) Dunal: Enhanced production of withanolides and phenolic acids from hairy root culture after application of elicitors
Withania somnifera (L.) Dunal: Enhanced production of withanolides and phenolic acids from hairy root culture after application of elicitors
Withania somnifera (L.) Dunal is an important Ayurvedic and indigenous medicinal plant in India belonging to the Solanacea...
Ki-67 is necessary during DNA replication for fork protection and genome stability
Ki-67 is necessary during DNA replication for fork protection and genome stability
The proliferation antigen Ki-67 has been widely used in clinical settings for cancer staging for many years, but investiga...
NRT1.1B mediates rice plant growth and soil microbial diversity under different nitrogen conditions
NRT1.1B mediates rice plant growth and soil microbial diversity under different nitrogen conditions
Interactions between microorganisms and plants can stimulate plant growth and promote nitrogen cycling. Nitrogen fertilize...
GC–IMS facilitates identification of carbapenem-resistant Klebsiella pneumoniae in simulated blood cultures
GC–IMS facilitates identification of carbapenem-resistant Klebsiella pneumoniae in simulated blood cultures
This study aimed to identify carbapenem-resistant Klebsiella pneumoniae (CRKP) based on changes in levels of its volatile ...
Rare multi-fungal sepsis: a case of triple-impact immunoparalysis
Rare multi-fungal sepsis: a case of triple-impact immunoparalysis
Patients with burn injury and inhalation injury are highly susceptible to infectious complications, including opportunisti...
Antifungal and antibiofilm effect of duloxetine hydrochloride against Cryptococcus neoformans and Cryptococcus gattii
Antifungal and antibiofilm effect of duloxetine hydrochloride against Cryptococcus neoformans and Cryptococcus gattii
Cryptococcosis is an invasive mycosis caused mainly by Cryptococcus gattii and C. neoformans and is treated with amphoteri...
Anti-Candida activity and biocompatibility of silver nanoparticles associated with denture glaze: a new approach to the management of denture stomatitis
Anti-Candida activity and biocompatibility of silver nanoparticles associated with denture glaze: a new approach to the management of denture stomatitis
The association of silver nanoparticles (AgNps) to sealant agent Palaseal® can be a promising alternative for complet...
阅读更多
format_indent_increase