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Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis in mice
Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis in mice
Tea polyphenols (TP) are the most biologically active components in tea, with antioxidant, antiobesity, and antitumor prop...
Novel bacterial plasmid produces small interfering RNAs (siRNAs) that induce effective gene silencing in the Asian citrus psyllid Diaphorina citri
KeywordsAsian citrus psyllidCandidatus Liberibacter asiaticusCitrus industryDiaphorina citridsRNA-producing plasmidGene si...
Complete assembly, annotation of virulence genes and CRISPR editing of the genome of Leishmania amazonensis PH8 strain
Available online 30 May 2023, 110661Author links open overlay panel, , , , , , , , , , Highlights•The L. amazonensis PH8 s...
Testing the generalizability of cfDNA fragmentomic features across different studies for cancer early detection
cfDNA fragmentomic features have been used in cancer detection models; however, the generalizability of the models needs t...
A survey of mapping algorithms in the long-reads era
A survey of mapping algorithms in the long-reads era
It has been over a decade since the first publication of a method dedicated entirely to mapping long-reads. The distinctiv...
Pervasive tandem duplications and convergent evolution shape coral genomes
Pervasive tandem duplications and convergent evolution shape coral genomes
Over the last decade, several coral genomes have been sequenced allowing a better understanding of these symbiotic organis...
mutscan—a flexible R package for efficient end-to-end analysis of multiplexed assays of variant effect data
mutscan—a flexible R package for efficient end-to-end analysis of multiplexed assays of variant effect data
Multiplexed assays of variant effect (MAVE) experimentally measure the effect of large numbers of sequence variants by sel...
Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application
Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application
Thrombosis is a common cause of vascular prosthesis failure. Antibody coating of prostheses to capture circulating endothe...
Culture of vibrating microtome tissue slices as a 3D model in biomedical research
Culture of vibrating microtome tissue slices as a 3D model in biomedical research
The basic idea behind the use of 3-dimensional (3D) tools in biomedical research is the assumption that the structures und...
Lysobacter changpingensis sp. nov., a novel species of the genus Lysobacter isolated from a rhizosphere soil of strawberry in China
Lysobacter changpingensis sp. nov., a novel species of the genus Lysobacter isolated from a rhizosphere soil of strawberry in China
In the present work, we characterized in detail strain CM-3-T8T, which was isolated from the rhizosphere soil of strawberr...
Inferring cell–cell communication at single-cell resolution
Inferring cell–cell communication at single-cell resolution
Existing methods to infer cell–cell communication from single-cell RNA-sequencing data fail to leverage the full inf...
Can microbes save the planet?
Genetic engineering and accelerated evolution of microbes aim to help climate change.
Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris
Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris
Insulin-like growth factor-1 (IGF-1) is a pleiotropic protein hormone and has become an attractive therapeutic target beca...
DEHP exposure impairs human skeletal muscle cell proliferation in primary culture conditions: preliminary study
DEHP exposure impairs human skeletal muscle cell proliferation in primary culture conditions: preliminary study
The plasticizer di (2-ethylhexyl) phthalate (DEHP) inhibits differentiation, impairs glucose metabolism, and decreases mit...
Development of a cell line from skeletal trunk muscle of the fish Labeo rohita
Development of a cell line from skeletal trunk muscle of the fish Labeo rohita
Labeo rohita is a widely cultivated tropical freshwater carp and found in rivers of South Asian region. A new cell line, d...
Evaluation of the new 2.0 version of the Roche SARS-CoV-2 Rapid Antigen Test
Volume 319, September 2023, 114758Author links open overlay panel, Highlights•We evaluated the new 2.0 version of the Roch...
Development of a chronic focal equine arteritis virus infection of a male reproductive tract cell line
Equine arteritis virus (EAV) is an Alphaarterivirus (family Arteriviridae, order Nidovirales) that frequently causes an in...
Targeted gene manipulation of Leloir pathway genes for the constitutive expression of β-galactosidase and its transgalactosylation product galacto-oligosaccharides from Kluyveromyces lactis GG799 and knockout strains
Kluyveromyces lactis is one of few yeast species that can utilize lactose or galactose as a sole source of carbon and ener...
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery
Volume 66, September 2023, 108176Author links open overlay panelHighlights•Large-scale (meta)genomic sequencing of underex...
Hierarchical Interleaved Bloom Filter: enabling ultrafast, approximate sequence queries
Hierarchical Interleaved Bloom Filter: enabling ultrafast, approximate sequence queries
We present a novel data structure for searching sequences in large databases: the Hierarchical Interleaved Bloom Filter (H...
Broad histone H4 monomethylation marks expressed genes involved in translation
Broad histone H4 monomethylation marks expressed genes involved in translation
H4K20me1 (histone H4 monomethylated at lysine 20) generally has a broad distribution along genes and has been reported to ...
Transcription start site mapping of a geminivirus using the in vitro cap-snatching of a tenuivirus
Geminiviruses are a family of single-stranded DNA viruses that cause significant yield losses in crop production worldwide...
Rapid identification of SARS-CoV-2 variants: Validation of the Simplexa SARS-CoV-2 Variant Direct assay
The circulation of certain SARS-CoV-2 variants may have a great impact on the epidemiological status of a geographical are...
Glycyrrhinic acid and probiotics alleviate deoxynivalenol-induced cytotoxicity in intestinal epithelial cells
Glycyrrhinic acid and probiotics alleviate deoxynivalenol-induced cytotoxicity in intestinal epithelial cells
Deoxynivalenol (DON) is one of the most prevalent mycotoxin contaminants, which posing a serious health threat to animals ...
Transcriptional profiling of exosomes derived from plasma of canine with mammary tumor by RNA-seq analysis
Canine mammary tumor (CMT) are the second most common tumor in dogs. Exosomes can act as biomarkers for the early diagnosi...
Inferring cell-type-specific causal gene regulatory networks during human neurogenesis
Inferring cell-type-specific causal gene regulatory networks during human neurogenesis
Genetic variation influences both chromatin accessibility, assessed in chromatin accessibility quantitative trait loci (ca...
Genomic and epigenomic determinants of heat stress-induced transcriptional memory in Arabidopsis
Genomic and epigenomic determinants of heat stress-induced transcriptional memory in Arabidopsis
Transcriptional regulation is a key aspect of environmental stress responses. Heat stress induces transcriptional memory, ...
Phylogenomics of transcriptionally active AP2/ERF and bHLH transcription factors and study of their promoter regions in Nothapodytes nimmoniana (J.Graham) Mabb
Phylogenomics of transcriptionally active AP2/ERF and bHLH transcription factors and study of their promoter regions in Nothapodytes nimmoniana (J.Graham) Mabb
Nothapodytes nimmoniana is a medicinally important plant producing anticancer monoterpene indole alkaloid (MIA), camptothe...
A splinkerette PCR-based genome walking technique for the identification of transgene integration sites in CHO cells
Chinese hamster ovary (CHO) cells are widely used to produce various recombinant therapeutic proteins due to several advan...
Metals and the cell surface of Cryptococcus neoformans
Recent studies in pathogenic yeasts reinforce our appreciation of the influence of metal homeostasis on the fungal cell su...
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