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Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors
Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors
There is evidence indicating that chemoresistance in tumor cells is mediated by the reconfiguration of the tricarboxylic a...
Near-infrared fluorescent molecular probes with cetuximab in the in vivo fluorescence imaging for epithelial ovarian cancer
Near-infrared fluorescent molecular probes with cetuximab in the in vivo fluorescence imaging for epithelial ovarian cancer
Near-infrared fluorescence (NIRF) imaging is an excellent choice for image-guided surgery due to its simple operation and ...
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles harboring IGF-1 improve ovarian function of mice with premature ovarian insufficiency through the Nrf2/HO-1 pathway
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles harboring IGF-1 improve ovarian function of mice with premature ovarian insufficiency through the Nrf2/HO-1 pathway
Premature ovarian insufficiency (POI) is a disease with medical, psychological and reproductive implications, but its comm...
Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA
Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA
Polycystic ovary syndrome (PCOS) is highly prevalent in women of reproductive age worldwide, exhibits highly heterogeneous...
MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis
MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis
Chemotherapy detrimentally impacts fertility via depletion of follicular reserves in the ovaries leading to ovarian failur...
Exploring lncRNA expression in follicular fluid exosomes of patients with obesity and polycystic ovary syndrome based on high-throughput sequencing technology
Exploring lncRNA expression in follicular fluid exosomes of patients with obesity and polycystic ovary syndrome based on high-throughput sequencing technology
Infertility is a reproductive health problem that attracts worldwide attention. Polycystic ovary syndrome (PCOS) is a majo...
SOX17 expression in ovarian clear cell carcinoma
SOX17 expression in ovarian clear cell carcinoma
Recent studies have revealed that the Sry-related HMG box gene 17 (SOX17) plays an important role in ovarian carcinogenesi...
Machine learning models in evaluating the malignancy risk of ovarian tumors: a comparative study
Machine learning models in evaluating the malignancy risk of ovarian tumors: a comparative study
The study aimed to compare the diagnostic efficacy of the machine learning models with expert subjective assessment (SA) i...
A novel ITGB8 transcript variant sustains ovarian cancer cell survival through genomic instability and altered ploidy on a mutant p53 background
A novel ITGB8 transcript variant sustains ovarian cancer cell survival through genomic instability and altered ploidy on a mutant p53 background
Transcript variants and protein isoforms are central to unique tissue functions and maintenance of homeostasis, in additio...
Causal relationship between inflammatory cytokines and polycystic ovary syndrome: a bidirectional mendelian randomization study
Causal relationship between inflammatory cytokines and polycystic ovary syndrome: a bidirectional mendelian randomization study
Polycystic ovary syndrome (PCOS) is defined as a chronic low-grade inflammatory reproductive endocrine disorder. PCOS can ...
ATF3 mediates PM2.5-induced apoptosis and inflammation in ovarian granulosa cells
ATF3 mediates PM2.5-induced apoptosis and inflammation in ovarian granulosa cells
Particulate matter 2.5 (PM2.5) pollution has emerged as a major global public health concern because of its adverse effect...
Progesterone peak influences embryonic developmental morphokinetics on trigger day? A retrospective study
Progesterone peak influences embryonic developmental morphokinetics on trigger day? A retrospective study
Premature Progesterone Rise (PPR) is characterized by elevated serum progesterone concentrations either towards the end of...
Implication of vasopressin receptor genes (AVPR1A and AVPR1B) in the susceptibility to polycystic ovary syndrome
Implication of vasopressin receptor genes (AVPR1A and AVPR1B) in the susceptibility to polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a complex heterogenous disorder manifesting with various reproductive, endocrine, and ...
A simple and practical approach to elective egg freezing to control costs and expand access to care
A simple and practical approach to elective egg freezing to control costs and expand access to care
Social elective egg freezing (EEF) is now widely used globally but in many countries is unaffordable to many women because...
Relationship between smoking, excessive androgen and negative emotions in women with polycystic ovary syndrome (PCOS)
Relationship between smoking, excessive androgen and negative emotions in women with polycystic ovary syndrome (PCOS)
Lifestyle intervention is the first-line treatment for PCOS. Numerous studies have investigated the effect of various life...
Inter-cycle variability of anti-Müllerian hormone: implications for predicting controlled ovarian stimulation cycle outcomes
Inter-cycle variability of anti-Müllerian hormone: implications for predicting controlled ovarian stimulation cycle outcomes
Anti-Müllerian hormone (AMH) is a widely used marker for estimating ovarian reserve, and it may predict response to o...
Risk-stratified CA125 screening integrating CA125 trajectories, trajectory-specific progression and transvaginal ultrasound for ovarian cancer
Risk-stratified CA125 screening integrating CA125 trajectories, trajectory-specific progression and transvaginal ultrasound for ovarian cancer
Cancer antigen 125 (CA125) is widely used for screening ovarian cancer (OC), yet its effectiveness remains debated. Potent...
Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial
Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial
Poor ovarian response (POR) to controlled ovarian stimulation (COS) remains challenging, especially in advanced-age women ...
Identification of three subtypes of ovarian cancer and construction of prognostic models based on immune-related genes
Identification of three subtypes of ovarian cancer and construction of prognostic models based on immune-related genes
Immunotherapy has revolutionized the treatment of ovarian cancer (OC), but different immune microenvironments often constr...
A preliminary study on the effects of Xiang Shao granules on reproductive endocrinology in drugged ovariectomised rats
A preliminary study on the effects of Xiang Shao granules on reproductive endocrinology in drugged ovariectomised rats
To establish a rat model of pharmacological ovariectomy by GnRH-a injection and to preliminarily investigate the reproduct...
MECOM Locus classical transcript isoforms affect tumor immune microenvironment and different targets in ovarian cancer
MECOM Locus classical transcript isoforms affect tumor immune microenvironment and different targets in ovarian cancer
The MECOM locus is a gene frequently amplified in high-grade serous ovarian carcinoma (HGSOC). Nevertheless, the body of r...
Nur77 ameliorates cyclophosphamide-induced ovarian insufficiency in mice by inhibiting oxidative damage and cell senescence
Nur77 ameliorates cyclophosphamide-induced ovarian insufficiency in mice by inhibiting oxidative damage and cell senescence
Premature ovarian failure (POF) is among the primary causes of ovarian dysfunction that severely affects women’s phy...
N-acetylcysteine supplementation improves endocrine-metabolism profiles and ovulation induction efficacy in polycystic ovary syndrome
N-acetylcysteine supplementation improves endocrine-metabolism profiles and ovulation induction efficacy in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) affects 6–20% of women worldwide, with insulin resistance and hyperinsulinemia occu...
Melatonin increases superoxide dismutase 2 (SOD2) levels and improves rat ovarian graft function after transplantation
Melatonin increases superoxide dismutase 2 (SOD2) levels and improves rat ovarian graft function after transplantation
Ovarian cryopreservation is a promising technique despite being hindered by damage from freezing and thawing. Melatonin ca...
Nanotechnology for boosting ovarian cancer immunotherapy
Nanotechnology for boosting ovarian cancer immunotherapy
Ovarian cancer, often referred to as the “silent killer,” is notoriously difficult to detect in its early stag...
Mesenchymal stem cell-derived extracellular vesicles therapy for primary ovarian insufficiency: a systematic review and meta-analysis of pre-clinical studies
Mesenchymal stem cell-derived extracellular vesicles therapy for primary ovarian insufficiency: a systematic review and meta-analysis of pre-clinical studies
Primary ovarian insufficiency (POI) manifests with hormonal imbalances, menstrual irregularities, follicle loss, and infer...
Seasonal environmental fluctuations alter the transcriptome dynamics of oocytes and granulosa cells in beef cows
Seasonal environmental fluctuations alter the transcriptome dynamics of oocytes and granulosa cells in beef cows
Examining the mechanistic cellular responses to heat stress could aid in addressing the increasing prevalence of decreased...
Withaferin A ameliorates ovarian cancer-induced renal damage through the regulation of expression of inflammatory cytokines
Withaferin A ameliorates ovarian cancer-induced renal damage through the regulation of expression of inflammatory cytokines
Cachexia a multifactorial syndrome is a common sequala in patients with cancer. It varies from 42 to 80% depending upon th...
Investigating PPT2’s role in ovarian cancer prognosis and immunotherapy outcomes
Investigating PPT2’s role in ovarian cancer prognosis and immunotherapy outcomes
Ovarian cancer (OC) remains the primary cause of mortality among gynecological malignancies, and the identification of rel...
Comprehensive in silico analysis of prognostic and immune infiltrates for FGFs in human ovarian cancer
Comprehensive in silico analysis of prognostic and immune infiltrates for FGFs in human ovarian cancer
Fibroblast growth factors (FGFs) are cell signaling proteins that perform multiple biological processes in many biological...
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