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ALKBH5 modulates macrophages polarization in tumor microenvironment of ovarian cancer
ALKBH5 modulates macrophages polarization in tumor microenvironment of ovarian cancer
Macrophages play an essential role in regulating ovarian cancer immune microenvironment. Studies have shown that m6A methy...
The impact of resveratrol on the outcome of the in vitro fertilization: an exploratory randomized placebo-controlled trial
The impact of resveratrol on the outcome of the in vitro fertilization: an exploratory randomized placebo-controlled trial
Resveratrol is a natural polyphenolic compound present in plants and red wine with many potential health benefits. This co...
Comprehensive DNA methylation profiling by MeDIP-NGS identifies potential genes and pathways for epithelial ovarian cancer
Comprehensive DNA methylation profiling by MeDIP-NGS identifies potential genes and pathways for epithelial ovarian cancer
Ovarian cancer, among all gynecologic malignancies, exhibits the highest incidence and mortality rate, primarily because i...
CAPN2 correlates with insulin resistance states in PCOS as evidenced by multi-dataset analysis
CAPN2 correlates with insulin resistance states in PCOS as evidenced by multi-dataset analysis
IR emerges as a feature in the pathophysiology of PCOS, precipitating ovulatory anomalies and endometrial dysfunctions tha...
Birth weight and premature ovarian insufficiency: a systematic review and meta-analysis
Birth weight and premature ovarian insufficiency: a systematic review and meta-analysis
To comprehensively evaluate the effect of low birth weight on premature ovarian insufficiency. We performed a systematic r...
The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation
The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation
Umbilical cord-derived mesenchymal stem cell (UCMSC) transplantation has been deeply explored for premature ovarian insuff...
Subsequent management and outcomes after first-line PARP inhibitors progression in ovarian cancer patients
Subsequent management and outcomes after first-line PARP inhibitors progression in ovarian cancer patients
This retrospective study aims to evaluating the subsequent management and outcomes after first-line PARPi progression in C...
Stearoyl-CoA desaturase 1 inhibition induces ER stress-mediated apoptosis in ovarian cancer cells
Stearoyl-CoA desaturase 1 inhibition induces ER stress-mediated apoptosis in ovarian cancer cells
Ovarian cancer is a leading cause of death among gynecologic tumors, often detected at advanced stages. Metabolic reprogra...
Sialyl-Tn serves as a potential therapeutic target for ovarian cancer
Sialyl-Tn serves as a potential therapeutic target for ovarian cancer
Ovarian cancer remains the deadliest of the gynecologic cancers in the United States. There have been limited advances in ...
Role of polyphenols in remodeling the host gut microbiota in polycystic ovary syndrome
Role of polyphenols in remodeling the host gut microbiota in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic condition in women of childbearing age and a major...
CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells
CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells
The gene cell division cycle associated 5 (CDCA5), also called sororin, has oncogenic characteristics and is upregulated i...
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway
Premature ovarian failure (POF) is a devastating condition for women under 40 years old. Chemotherapy, especially the use ...
Cre-LoxP and tamoxifen-induced deletion of ovarian quiescin sulfhydryl oxidase 2 showed disruption of ovulatory activity in mice
Cre-LoxP and tamoxifen-induced deletion of ovarian quiescin sulfhydryl oxidase 2 showed disruption of ovulatory activity in mice
Quiescin sulfhydryl oxidase 2 (QSOX2) is a flavin adenine dinucleotide-dependent sulfhydryl oxidase that is known to be in...
Identification and validation of IRF6 related to ovarian cancer and biological function and prognostic value
Identification and validation of IRF6 related to ovarian cancer and biological function and prognostic value
Ovarian cancer (OC) is a severe gynecological malignancy with significant diagnostic and therapeutic challenges. The disco...
Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1
Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1
Lymph node metastasis (LNM) is a major factor contributing to the high mortality rate of ovarian cancer, making the treatm...
Mesonephric-like adenocarcinoma of the ovary
Mesonephric-like adenocarcinoma of the ovary
Mesonephric-like adenocarcinoma is a new class of rare subtypes of the female reproductive system. Its clinical symptoms a...