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Bile acids in follicular fluid: potential new therapeutic targets and predictive markers for women with diminished ovarian reserve
Bile acids in follicular fluid: potential new therapeutic targets and predictive markers for women with diminished ovarian reserve
To investigate the changes in bile acid (BA) metabolites within the follicular fluid (FF) of patients with diminished ovar...
Comparative efficacy and safety of metformin, anti-obesity agents, and myoinositol in improving IVF/ICSI outcomes and reducing ovarian hyperstimulation syndrome in women with polycystic ovary syndrome: a systematic review and network meta-analysis
Comparative efficacy and safety of metformin, anti-obesity agents, and myoinositol in improving IVF/ICSI outcomes and reducing ovarian hyperstimulation syndrome in women with polycystic ovary syndrome: a systematic review and network meta-analysis
To compare the efficacy and safety of metformin, anti-obesity agents, and inositol with polycystic ovary syndrome (PCOS) u...
Unveiling the link: anti-protein disulfide isomerase A3 autoantibody expression and polycystic ovary syndrome risk in euthyroid autoimmune thyroiditis women
Unveiling the link: anti-protein disulfide isomerase A3 autoantibody expression and polycystic ovary syndrome risk in euthyroid autoimmune thyroiditis women
Polycystic ovary syndrome (PCOS) is a common complication of autoimmune thyroiditis (AIT) in women, but the underlying mec...
Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway
Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway
Cisplatin (DDP) is one of the most effective anticancer drugs, commonly used to treat advanced ovarian cancer (OC). Howeve...
TIGIT+ CD4+ regulatory T cells enhance PD-1 expression on CD8+ T cells and promote tumor growth in a murine ovarian cancer model
TIGIT+ CD4+ regulatory T cells enhance PD-1 expression on CD8+ T cells and promote tumor growth in a murine ovarian cancer model
Immune checkpoint-based immunotherapy has shown limited efficacy in the treatment of ovarian cancer. In recent years, the ...
Exploring the innovative application of cerium oxide nanoparticles for addressing oxidative stress in ovarian tissue regeneration
Exploring the innovative application of cerium oxide nanoparticles for addressing oxidative stress in ovarian tissue regeneration
The female reproductive system dysfunction considerably affects the overall health of women and children on a global scale...
The melanocortin receptor genes are linked to and associated with the risk of polycystic ovary syndrome in Italian families
The melanocortin receptor genes are linked to and associated with the risk of polycystic ovary syndrome in Italian families
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder occurring in women of reproductive age. The disease...
Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironment
Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironment
High-grade serous ovarian cancer (HGSOC) is marked by significant molecular diversity, presenting a major clinical challen...
Searching for the ‘X’ factor: investigating the genetics of primary ovarian insufficiency
Searching for the ‘X’ factor: investigating the genetics of primary ovarian insufficiency
Primary ovarian insufficiency (POI) is the cessation of ovarian function before the age of 40. The causes of POI are heter...
Unraveling the complexity of follicular fluid: insights into its composition, function, and clinical implications
Unraveling the complexity of follicular fluid: insights into its composition, function, and clinical implications
Follicular fluid (FF) plays a vital role in the bidirectional communication between oocytes and granulosa cells (GCs), reg...
Nicotinamide mononucleotide improves the ovarian reserve of POI by inhibiting NLRP3-mediated pyroptosis of ovarian granulosa cells
Nicotinamide mononucleotide improves the ovarian reserve of POI by inhibiting NLRP3-mediated pyroptosis of ovarian granulosa cells
Premature ovarian insufficiency (POI) is a common clinical problem, but there is currently no effective treatment. NLRP3 i...
Gut microbiota and gut-derived metabolites are altered and associated with dietary intake in women with polycystic ovary syndrome
Gut microbiota and gut-derived metabolites are altered and associated with dietary intake in women with polycystic ovary syndrome
Disturbances in the gut microbiota may act as mechanisms influencing the interplay between dietary factors and metabolic d...
Single-cell sequencing reveals PTX3 involvement in ovarian cancer metastasis
Single-cell sequencing reveals PTX3 involvement in ovarian cancer metastasis
Pentraxin 3 (PTX3) has been associated with the development and progression of various malignant tumors. However, its role...
Unveiling the power of mitochondrial transfer in cancer progression: a perspective in ovarian cancer
Unveiling the power of mitochondrial transfer in cancer progression: a perspective in ovarian cancer
Mitochondria are dynamic organelles integral to metabolic processes, coordination of essential biological pathways, and on...
The predictive role of PD-L1 expression and CD8 + TIL levels in determining the neoadjuvant chemotherapy response in advanced ovarian cancer
The predictive role of PD-L1 expression and CD8 + TIL levels in determining the neoadjuvant chemotherapy response in advanced ovarian cancer
To analyze how the PD-L1 expression and CD8 + tumor infiltrating lymphocyte (TIL) levels in biopsy samples bef...
Chiglitazar ameliorates dehydroepiandrosterone-induced polycystic ovary syndrome in rats
Chiglitazar ameliorates dehydroepiandrosterone-induced polycystic ovary syndrome in rats
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder accompanied by ovulatory dysfunction. Insulin resi...
Characterization of the gut microbiota in patients with SARS-CoV-2 infection during controlled ovarian stimulation
Characterization of the gut microbiota in patients with SARS-CoV-2 infection during controlled ovarian stimulation
The Coronavirus disease 2019 (COVID-19) pandemic has emerged as a global health crisis, with clinical manifestations inclu...
Correction: Correlation between ovarian follicular development and Hippo pathway in polycystic ovary syndrome
Correction: Correlation between ovarian follicular development and Hippo pathway in polycystic ovary syndrome
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors
Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors
There is evidence indicating that chemoresistance in tumor cells is mediated by the reconfiguration of the tricarboxylic a...
Near-infrared fluorescent molecular probes with cetuximab in the in vivo fluorescence imaging for epithelial ovarian cancer
Near-infrared fluorescent molecular probes with cetuximab in the in vivo fluorescence imaging for epithelial ovarian cancer
Near-infrared fluorescence (NIRF) imaging is an excellent choice for image-guided surgery due to its simple operation and ...
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles harboring IGF-1 improve ovarian function of mice with premature ovarian insufficiency through the Nrf2/HO-1 pathway
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles harboring IGF-1 improve ovarian function of mice with premature ovarian insufficiency through the Nrf2/HO-1 pathway
Premature ovarian insufficiency (POI) is a disease with medical, psychological and reproductive implications, but its comm...
Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA
Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA
Polycystic ovary syndrome (PCOS) is highly prevalent in women of reproductive age worldwide, exhibits highly heterogeneous...
MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis
MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis
Chemotherapy detrimentally impacts fertility via depletion of follicular reserves in the ovaries leading to ovarian failur...
Exploring lncRNA expression in follicular fluid exosomes of patients with obesity and polycystic ovary syndrome based on high-throughput sequencing technology
Exploring lncRNA expression in follicular fluid exosomes of patients with obesity and polycystic ovary syndrome based on high-throughput sequencing technology
Infertility is a reproductive health problem that attracts worldwide attention. Polycystic ovary syndrome (PCOS) is a majo...
SOX17 expression in ovarian clear cell carcinoma
SOX17 expression in ovarian clear cell carcinoma
Recent studies have revealed that the Sry-related HMG box gene 17 (SOX17) plays an important role in ovarian carcinogenesi...
Machine learning models in evaluating the malignancy risk of ovarian tumors: a comparative study
Machine learning models in evaluating the malignancy risk of ovarian tumors: a comparative study
The study aimed to compare the diagnostic efficacy of the machine learning models with expert subjective assessment (SA) i...
A novel ITGB8 transcript variant sustains ovarian cancer cell survival through genomic instability and altered ploidy on a mutant p53 background
A novel ITGB8 transcript variant sustains ovarian cancer cell survival through genomic instability and altered ploidy on a mutant p53 background
Transcript variants and protein isoforms are central to unique tissue functions and maintenance of homeostasis, in additio...
Causal relationship between inflammatory cytokines and polycystic ovary syndrome: a bidirectional mendelian randomization study
Causal relationship between inflammatory cytokines and polycystic ovary syndrome: a bidirectional mendelian randomization study
Polycystic ovary syndrome (PCOS) is defined as a chronic low-grade inflammatory reproductive endocrine disorder. PCOS can ...
ATF3 mediates PM2.5-induced apoptosis and inflammation in ovarian granulosa cells
ATF3 mediates PM2.5-induced apoptosis and inflammation in ovarian granulosa cells
Particulate matter 2.5 (PM2.5) pollution has emerged as a major global public health concern because of its adverse effect...
Progesterone peak influences embryonic developmental morphokinetics on trigger day? A retrospective study
Progesterone peak influences embryonic developmental morphokinetics on trigger day? A retrospective study
Premature Progesterone Rise (PPR) is characterized by elevated serum progesterone concentrations either towards the end of...
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