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Engineering metaphase spindles: Construction site and building blocks
Volume 79, December 2022, 102143Author links open overlay panelAbstractIn an active, crowded cytoplasm, eukaryotic cells c...
Highly conserved, but highly specific: Somatic cell–cell fusion in filamentous fungi
The development of ascomycete fungal colonies involves cell–cell fusion at different growth stages. In the model fungus Ne...
Emergence of neuron types
Neuron types are the building blocks of the nervous system, and therefore, of functional circuits. Understanding the origi...
Myosin motors in sensory hair bundle assembly
Volume 79, December 2022, 102132AbstractMechanosensory hair bundles are assembled from actin-based stereocilia that projec...
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Manipulation of epithelial cell architecture by the bacterial pathogens Listeria and Shigella
Volume 79, December 2022, 102131AbstractSubversion of the host cell cytoskeleton is a virulence attribute common to many b...
Signaling oscillations: Molecular mechanisms and functional roles
Volume 78, October 2022, 102130AbstractMounting evidence shows that oscillatory activity is widespread in cell signaling. ...
The role of spatiotemporal organization and dynamics of clock complexes in circadian regulation
Volume 78, October 2022, 102129AbstractCircadian clocks are cell autonomous timekeepers that regulate ∼24-h oscillations i...
Editorial overview: Membranes in perpetual motion
Benjamin Glick is a Professor of Molecular Genetics and Cell Biology at the University of Chicago. His laboratory studies ...
Transport-dependent maturation of organelles in neurons
Volume 78, October 2022, 102121Highlights•Several organelles spatially segregate and form a maturation gradient along the ...
Editorial: Emerging concepts and tools in genome organization and chromatin function in eukaryotes
Kazuhiro Maeshima obtained his Ph.D. from the Osaka University in Japan on the biochemical and biophysical analyses of pro...
ER and Golgi trafficking in axons, dendrites, and glial processes
Volume 78, October 2022, 102119AbstractBoth neurons and glia in mammalian brains are highly ramified. Neurons form complex...
Riding brain “waves” to identify human memory genes
Volume 78, October 2022, 102118AbstractWhile there is extensive research on memory-related oscillations and brain gene exp...
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Stand by me: Fibroblasts regulation of the intestinal epithelium during development and homeostasis
Volume 78, October 2022, 102116AbstractThe epithelium of the small intestine is composed of a single layer of cells that l...
Myosins and membrane trafficking in intestinal brush border assembly
Volume 77, August 2022, 102117AbstractMyosins are a class of motors that participate in a wide variety of cellular functio...
Making and breaking the inner nuclear membrane proteome
Volume 78, October 2022, 102115AbstractThe nuclear envelope (NE) is the defining feature of eukaryotic cells, separating t...
Beyond the centrosome: The mystery of microtubule organising centres across mammalian preimplantation embryos
Volume 77, August 2022, 102114Highlights•Centrosome dynamics during the first mitotic division influence the vulnerability...
Building the phagocytic cup on an actin scaffold
Volume 77, August 2022, 102112AbstractCells ingest large particles, such as bacteria, viruses, or apoptotic cells, via the...
Electrifying rhythms in plant cells
Volume 77, August 2022, 102113Highlights•Oscillations are found in all spatiotemporal scales of biological organization.•U...
Development of a multiciliated cell
Volume 77, August 2022, 102105AbstractMulticiliated cells (MCC) are evolutionary conserved, highly specialized cell types ...
Reading oscillatory instructions: How cells achieve time-dependent responses to oscillating transcription factors
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Biomolecular condensates in epithelial junctions
Volume 77, August 2022, 102089AbstractEpithelial junctions are transmembrane protein complexes that regulate cell adhesion...
Sperm-specific proteins: new implications for diagnostic development and cancer immunotherapy
Volume 77, August 2022, 102104Highlights•Sperm-specific proteins were thought to remain within the seminiferous tubules, p...
Encoding and decoding NF-κB nuclear dynamics
Volume 77, August 2022, 102103Highlights•Cells exploit the NF-κB pathway to respond to environmental changes.•Signal encod...
Mining cell–cell signaling in single-cell transcriptomics atlases
Volume 76, June 2022, 102101AbstractRecent advances in single-cell RNA sequencing (scRNA-seq) techniques lead to an explos...
Actin nucleoskeleton in embryonic development and cellular differentiation
Volume 76, June 2022, 102100Highlights•Dynamic assembly and disassembly of nuclear actin form the nucleoskeleton.•The acti...
Roles of PIKfyve in multiple cellular pathways
Volume 76, June 2022, 102086AbstractPhosphoinositide signaling lipids are crucial for eukaryotes and regulate many aspects...