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Unveiling the intricacies of paraspeckle formation and function
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Post-transcriptional regulation as a conserved driver of neural crest and cancer-cell migration
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Roles of membrane mechanics-mediated feedback in membrane traffic
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The relationship between nucleosome positioning and higher-order genome folding
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Follow the flow: Actin and membrane act as an integrated system to globally coordinate cell shape and movement
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Canonical and noncanonical regulators of centromere assembly and maintenance
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Replicating chromatin in the nucleus: A histone variant perspective
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New advances in innate immune endosomal trafficking
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Transient, nano-scale, liquid-like molecular assemblies coming of age
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Biomolecular condensates as drivers of membrane trafficking and remodelling
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Mitochondrial motility modulators coordinate quality control dynamics to promote neuronal health
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The third dimension of the actin cortex
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Disruptions in axonal lysosome transport and its contribution to neurological disease
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Nucleolar organization and ribosomal DNA stability in response to DNA damage
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Structural determinants of intermediate filament mechanics
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Computational tools for cellular scale biophysics
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In silico labeling in cell biology: Potential and limitations
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Characterizing intracellular mechanics via optical tweezers-based microrheology
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Lipid osmosis, membrane tension, and other mechanochemical driving forces of lipid flow
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Chromatin plasticity in mechanotransduction
Chromatin plasticity in mechanotransduction
Living organisms can detect and respond to physical forces at the cellular level. The pathways that transmit these forces ...
The adaptable caveola coat generates a plasma membrane sensory system
The adaptable caveola coat generates a plasma membrane sensory system
Caveolae are atypical plasma membrane invaginations that take part in lipid sorting and regulation of oxidative and mechan...
Nonlinear dynamics in phosphoinositide metabolism
Nonlinear dynamics in phosphoinositide metabolism
Phosphoinositides broadly impact membrane dynamics, signal transduction and cellular physiology. The orchestration of sign...
Phosphatidylinositol 3,4-bisphosphate: Out of the shadows and into the spotlight
Phosphatidylinositol 3,4-bisphosphate: Out of the shadows and into the spotlight
Phosphoinositide 3-kinases regulate many cellular functions, including migration, growth, proliferation, and cell survival...
The mitogen-activated protein kinase network, wired to dynamically function at multiple scales
The mitogen-activated protein kinase network, wired to dynamically function at multiple scales
The mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) signaling network is a key transdu...
Single molecule imaging unveils cellular architecture, dynamics and mechanobiology
Single molecule imaging unveils cellular architecture, dynamics and mechanobiology
Single molecule fluorescence imaging techniques have provided many novel insights into the organization and dynamics of mo...
Nuclear lipid droplet: Guardian of nuclear membrane lipid homeostasis?
Nuclear lipid droplet: Guardian of nuclear membrane lipid homeostasis?
Lipid droplets (LDs) are unique organelles characterized by a surface phospholipid monolayer and a lipid ester core, made ...
Helical motion and torque generation by microtubule motors
Helical motion and torque generation by microtubule motors
Microtubule motors play key roles in cellular functions, such as transport, mitosis and cell motility. Fueled by ATP hydro...
Mechanisms governing vesicle traffic at the Golgi apparatus
Mechanisms governing vesicle traffic at the Golgi apparatus
Vesicle transport at the Golgi apparatus is a well-described process, and the major protein components involved have been ...
Tubulin posttranslational modifications through the lens of new technologies
Tubulin posttranslational modifications through the lens of new technologies
The Tubulin Code revolutionizes our understanding of microtubule dynamics and functions, proposing a nuanced system govern...
Biogenesis of extracellular vesicles from the pathogen perspective: Transkingdom strategies for delivering messages
Biogenesis of extracellular vesicles from the pathogen perspective: Transkingdom strategies for delivering messages
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles containing proteins, nucleic acids or lipids [1]. EVs are...
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