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Bezos backs taste-good lab proteins
Jeff Bezos is bankrolling two new centers to research and develop sustainable proteins that taste good and can be produced...
Citizen chickpeas
The European Union’s biggest citizen science prize for an initiative with the most impact in advancing a sustainable socie...
Vision–language AI assistance in human pathology
Pathologists have access to increasingly accurate artificial intelligence (AI) models that can make task-specific or agnos...
Roche bets on RNA exon editor
Roche has struck a partnership with neuro-focused biotech Ascidian Therapeutics over an RNA editing platform. The deal see...
Counteracting tissue aging through TERT activation
Telomere dysfunction is one of the primary hallmarks of aging, causing molecular and cellular damage that is associated wi...
Forum: Lancaster and Pașca
Forum: Lancaster and Pașca
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Cryo-EM structure of a prime editor complex in multiple states
Prime editing systems combine a SpCas9 protein with a reverse transcriptase and a prime editing guide RNA (pegRNA) to inst...
Breathing new life into in vivo lung editing
New lipid nanoparticle designs make targeted in vivo lung editing possible in mice and may lead to new treatment options f...
Author Correction: High-yield porphyrin production through metabolic engineering and biocatalysis
These authors contributed equally: Haihong Chen, Yaohong Wang, Weishan Wang, Ting Cao, Lu Zhang.State Key Laboratory of Bi...
CRISPR screens of tumor-infiltrating NK cells identify genetic checkpoints for CAR-NK therapy
CRISPR screens of tumor-infiltrating NK cells identify genetic checkpoints for CAR-NK therapy
We use a CRISPR screening platform based on adeno-associated virus and the Sleeping Beauty transposon (AAV-SB-CRISPR) to p...
Increasing access to biotech products for animal agriculture in Sub-Saharan Africa through partnerships
Increasing access to biotech products for animal agriculture in Sub-Saharan Africa through partnerships
The authors would like to thank Government of Uganda, National Agricultural Research Organisation, Ministry of Agriculture...
Author Correction: Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms
Ludwig Institute for Cancer Research, Lausanne Branch, Department of Oncology, Lausanne University Hospital (CHUV) and Uni...
In vivo AAV–SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy
In vivo AAV–SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy
Natural killer (NK) cells have clinical potential against cancer; however, multiple limitations hinder the success of NK c...
Machine learning prediction of prime editing efficiency across diverse chromatin contexts
Machine learning prediction of prime editing efficiency across diverse chromatin contexts
The success of prime editing depends on the prime editing guide RNA (pegRNA) design and target locus. Here, we developed m...
Editor’s pick: Tenpoint Therapeutics
Editor’s pick: Tenpoint Therapeutics
Each year, Nature Biotechnology highlights companies that have received sizeable early-stage funding in the previous year....
Tracking gene order provides a new perspective on intraspecific evolution in microbiotas
Tracking gene order provides a new perspective on intraspecific evolution in microbiotas
We developed SynTracker, a tool to track conspecific microbial strains using genome synteny. SynTracker is sensitive to ge...
Editor’s pick: Tome Biosciences
Editor’s pick: Tome Biosciences
Each year, Nature Biotechnology highlights companies that have received sizeable early-stage funding in the previous year....
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
Microbial species diversify into strains through single-nucleotide mutations and structural changes, such as recombination...
Effects of the first successful lawsuit against a consumer neurotechnology company for violating brain data privacy
On 9 August 2023 the Supreme Court of Chile (SCC) ruled in favor of former senator Guido Girardi in a constitutional prote...
Engineered yeast produces the plant-based vaccine adjuvant QS-21
Extracting pharmacological compounds from plants can be ecologically damaging and often results in low yields, which limit...
OpenFold provides insights into AlphaFold2’s learning behavior
Despite the immense utility of AlphaFold2 in predicting protein structure, the official implementation excludes code for i...
Honey without bees
Honey without bees
A food tech startup based in the Netherlands is making honey by replacing the bee’s stomach with synt...
A vaccine strategy for inducing broadly neutralizing antibodies against HIV
An effective HIV vaccine must induce broadly neutralizing antibodies (bnAbs) that target the most conserved sites of the H...
First-in-class T cell engager approved for lung cancer
Amgen’s T cell engager Imdelltra (tarlatamab) has gained FDA accelerated approval for an aggressive type of cell lung canc...
Forum: Anikeeva, Courtine and Bloch
Forum: Anikeeva, Courtine and Bloch
On this episode, Chief Editor Barbara Cheifet speaks with Polina Anikeeva from MIT, Grégoire Courtine from EPFL, and Jocel...
Gene therapy restores hearing
Regeneron Pharmaceuticals has released preliminary data from the first two patients treated with the investigational gene ...
Precision radiation opens a new window on cancer therapy
Precision radiation opens a new window on cancer therapy
Targeted radiopharmaceuticals offer resistance-free potency, pre-treatment imaging and widespread combination potential. B...
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Subclonal reconstruction algorithms use bulk DNA sequencing data to quantify parameters of tumor evolution, allowing an as...
Cis-editing for all
CRISPR technologies offer new opportunities to democratize gene-edited crops and promote global sustainability.
Author Correction: Why Japan lacks a vibrant biotech industry
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