The Role and Research Progress of Mitochondria in Sensorineural Hearing Loss

Coffin AB, Rubel EW, Raible DW (2013) Bax, Bcl2, and p53 differentially regulate neomycin- and gentamicin-induced hair cell death in the zebrafish lateral line. J Assoc Res Otolaryngol: JARO 14:645–659. https://doi.org/10.1007/s10162-013-0404-1

Article  PubMed  PubMed Central  Google Scholar 

Tan WJT, Song L (2023) Role of mitochondrial dysfunction and oxidative stress in sensorineural hearing loss. Hear Res 434:108783. https://doi.org/10.1016/j.heares.2023.108783

Article  PubMed  Google Scholar 

Hutchin TP, Cortopassi GA (2000) Mitochondrial defects and hearing loss. Cell Mol Life Sci: CMLS 57:1927–1937. https://doi.org/10.1007/pl00000673

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zheng J, Ji Y, Guan MX (2012) Mitochondrial tRNA mutations associated with deafness. Mitochondrion 12:406–413. https://doi.org/10.1016/j.mito.2012.04.001

Article  CAS  PubMed  Google Scholar 

Fu X et al (2021) Mechanism and prevention of ototoxicity induced by aminoglycosides. Front Cell Neurosci 15:692762. https://doi.org/10.3389/fncel.2021.692762

Article  CAS  PubMed  PubMed Central  Google Scholar 

Johnson KR, Zheng QY, Bykhovskaya Y, Spirina O, Fischel-Ghodsian N (2001) A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice. Nat Genet 27:191–194. https://doi.org/10.1038/84831

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tan WJT et al (2017) Novel role of the mitochondrial protein Fus1 in protection from premature hearing loss via regulation of oxidative stress and nutrient and energy sensing pathways in the inner ear. Antioxid Redox Signal 27:489–509. https://doi.org/10.1089/ars.2016.6851

Article  CAS  PubMed  PubMed Central  Google Scholar 

Niu X, Trifunovic A, Larsson NG, Canlon B (2007) Somatic mtDNA mutations cause progressive hearing loss in the mouse. Exp Cell Res 313:3924–3934. https://doi.org/10.1016/j.yexcr.2007.05.029

Article  CAS  PubMed  Google Scholar 

Xie C et al (2022) Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow. Nat Biomed Eng 6:76–93. https://doi.org/10.1038/s41551-021-00819-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li P et al (2023) Mitochondrial dysfunction in hearing loss: oxidative stress, autophagy and NLRP3 inflammasome. Front Cell Dev Biol 11:1119773. https://doi.org/10.3389/fcell.2023.1119773

Article  PubMed  PubMed Central  Google Scholar 

Yu X et al (2021) The expression of PHB2 in the cochlea: possible relation to age-related hearing loss. Cell Biol Int 45:2490–2498. https://doi.org/10.1002/cbin.11693

Article  CAS  PubMed  Google Scholar 

Anderson S et al (1981) Sequence and organization of the human mitochondrial genome. Nature 290:457–465. https://doi.org/10.1038/290457a0

Article  CAS  PubMed  Google Scholar 

Kauppila TES, Kauppila JHK, Larsson NG (2017) Mammalian mitochondria and aging: an update. Cell Metab 25:57–71. https://doi.org/10.1016/j.cmet.2016.09.017

Article  CAS  PubMed  Google Scholar 

Markaryan A, Nelson EG, Hinojosa R (2009) Quantification of the mitochondrial DNA common deletion in presbycusis. Laryngoscope 119:1184–1189. https://doi.org/10.1002/lary.20218

Article  CAS  PubMed  Google Scholar 

Mkaouar-Rebai E et al (2010) Whole mitochondrial genome screening in two families with hearing loss: detection of a novel mutation in the 12S rRNA gene. Biosci Rep 30:405–411. https://doi.org/10.1042/bsr20090120

Article  CAS  PubMed  Google Scholar 

Muyderman H et al (2012) The mitochondrial T1095C mutation increases gentamicin-mediated apoptosis. Mitochondrion 12:465–471. https://doi.org/10.1016/j.mito.2012.06.006

Article  CAS  PubMed  Google Scholar 

Ibrahim I, Dominguez-Valentin M, Segal B, Zeitouni A, da Silva SD (2018) Mitochondrial mutations associated with hearing and balance disorders. Mutat Res 810:39–44. https://doi.org/10.1016/j.mrfmmm.2018.03.003

Article  CAS  PubMed  Google Scholar 

Kokotas H et al (2011) Detection of deafness-causing mutations in the Greek mitochondrial genome. Dis Markers 30:283–289. https://doi.org/10.3233/dma-2011-0786

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li X et al (2004) Biochemical characterization of the mitochondrial tRNASer(UCN) T7511C mutation associated with nonsyndromic deafness. Nucleic Acids Res 32:867–877. https://doi.org/10.1093/nar/gkh226

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maassen JA et al (2004) Mitochondrial diabetes: molecular mechanisms and clinical presentation. Diabetes 53(Suppl 1):S103-109. https://doi.org/10.2337/diabetes.53.2007.s103

Article  CAS  PubMed  Google Scholar 

Chomyn A, Enriquez JA, Micol V, Fernandez-Silva P, Attardi G (2000) The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode syndrome-associated human mitochondrial tRNALeu(UUR) mutation causes aminoacylation deficiency and concomitant reduced association of mRNA with ribosomes. J Biol Chem 275:19198–19209. https://doi.org/10.1074/jbc.M908734199

Article  CAS  PubMed  Google Scholar 

Li R, Guan MX (2010) Human mitochondrial leucyl-tRNA synthetase corrects mitochondrial dysfunctions due to the tRNALeu(UUR) A3243G mutation, associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like symptoms and diabetes. Mol Cell Biol 30:2147–2154. https://doi.org/10.1128/mcb.01614-09

Article  CAS  PubMed  PubMed Central  Google Scholar 

Levinger L, Giegé R, Florentz C (2003) Pathology-related substitutions in human mitochondrial tRNA(Ile) reduce precursor 3′ end processing efficiency in vitro. Nucleic Acids Res 31:1904–1912. https://doi.org/10.1093/nar/gkg282

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gutiérrez Cortés N et al (2012) Novel mitochondrial DNA mutations responsible for maternally inherited nonsyndromic hearing loss. Hum Mutat 33:681–689. https://doi.org/10.1002/humu.22023

Article  CAS  PubMed  Google Scholar 

Yan X et al (2011) Maternally transmitted late-onset non-syndromic deafness is associated with the novel heteroplasmic T12201C mutation in the mitochondrial tRNAHis gene. J Med Genet 48:682–690. https://doi.org/10.1136/jmedgenet-2011-100219

Article  CAS  PubMed  Google Scholar 

Ding Y, Leng J, Fan F, Xia B, Xu P (2013) The role of mitochondrial DNA mutations in hearing loss. Biochem Genet 51:588–602. https://doi.org/10.1007/s10528-013-9589-6

Article  CAS  PubMed  Google Scholar 

Lévêque M et al (2007) Whole mitochondrial genome screening in maternally inherited non-syndromic hearing impairment using a microarray resequencing mitochondrial DNA chip. Eur J Hum Genet: EJHG 15:1145–1155. https://doi.org/10.1038/sj.ejhg.5201891

Article  CAS  PubMed 

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