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Major cardiovascular events in patients with cardiovascular monosodium urate deposits in atherosclerotic plaques
Major cardiovascular events in patients with cardiovascular monosodium urate deposits in atherosclerotic plaques
AbstractObjective. To determine the association of cardiovascular atherosclerotic plaque monosodium urate deposits with th...
Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial
Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial
AbstractObjective. We explored the efficacy and safety of brentuximab vedotin, a chimeric anti-CD30 antibody drug conjugat...
Deep Learning Enables Automatic Detection of Joint Damage Progression in Rheumatoid Arthritis—Model Development and External Validation
Deep Learning Enables Automatic Detection of Joint Damage Progression in Rheumatoid Arthritis—Model Development and External Validation
AbstractObjectives. Although deep learning has demonstrated substantial potential in automatic quantification of joint dam...
Hydroxychloroquine-induced pigmentation in rheumatic diseases: prevalence, clinical features and influencing factors
Hydroxychloroquine-induced pigmentation in rheumatic diseases: prevalence, clinical features and influencing factors
AbstractObjective. To describe the clinical features of Chinese patients with hydroxychloroquine (HCQ)-induced pigmentatio...
Long-term clinical outcomes in early rheumatoid arthritis that was treated-to-target in the BeSt and IMPROVED studies
Long-term clinical outcomes in early rheumatoid arthritis that was treated-to-target in the BeSt and IMPROVED studies
AbstractObjectives. To assess disease outcomes after 20 and 12 years of patients with rheumatoid (RA) or undifferentiated ...
Long-term efficacy and safety of subcutaneous tocilizumab in clinical trials of polyarticular or systemic juvenile idiopathic arthritis
Long-term efficacy and safety of subcutaneous tocilizumab in clinical trials of polyarticular or systemic juvenile idiopathic arthritis
AbstractObjective. To investigate the safety and efficacy of subcutaneous tocilizumab (SC-TCZ) treatment in a long-term ex...
Efficacy of methylprednisolone in very early systemic sclerosis: results of the “Hit hard and early’’ randomized controlled trial
Efficacy of methylprednisolone in very early systemic sclerosis: results of the “Hit hard and early’’ randomized controlled trial
AbstractObjective. We hypothesized that glucocorticoids would induce remission in very early Systemic Sclerosis patients b...
Description of a novel splice site variant in UBA1 gene causing VEXAS syndrome
Description of a novel splice site variant in UBA1 gene causing VEXAS syndrome
AbstractObjective. The vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is a complex immune disor...
Systemic sclerosis-associated pulmonary arterial hypertension is characterized by a distinct peripheral T helper cell profile
Systemic sclerosis-associated pulmonary arterial hypertension is characterized by a distinct peripheral T helper cell profile
AbstractObjectives. Systemic sclerosis (SSc) is characterized by multiple clinical manifestations. Vasculopathy is a main ...
The worldwide prevalence of psoriatic arthritis—a systematic review and meta-analysis
The worldwide prevalence of psoriatic arthritis—a systematic review and meta-analysis
AbstractObjectives. Previous attempts to pool prevalence studies in PsA have failed to take account of important methodolo...
Capi-score: a quantitative algorithm for identifying disease patterns in nailfold videocapillaroscopy
Capi-score: a quantitative algorithm for identifying disease patterns in nailfold videocapillaroscopy
AbstractObjectives. The European Alliance of Associations for Rheumatology (EULAR) supports the use of nailfold videocapil...
Thorough assessment of the effectiveness of belimumab in a large Spanish multicenter cohort of systemic lupus erythematosus patients
Thorough assessment of the effectiveness of belimumab in a large Spanish multicenter cohort of systemic lupus erythematosus patients
AbstractObjectives. To provide an overview on the current use of belimumab (BLM) in SLE patients in clinical practice and ...
Enhancing current guidance for psoriatic arthritis and its comorbidities: recommendations from an expert consensus panel
Enhancing current guidance for psoriatic arthritis and its comorbidities: recommendations from an expert consensus panel
AbstractObjectives. Existing guidelines for psoriatic arthritis (PsA) cover many aspects of management. Some gaps remain r...
Uptake and safety of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide observational study
Uptake and safety of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide observational study
AbstractObjective. The uptake and safety of pneumococcal vaccination in people with immune mediated inflammatory diseases ...
Machine learning-driven immunophenotypic stratification of mixed connective tissue disease corroborating the clinical heterogeneity
Machine learning-driven immunophenotypic stratification of mixed connective tissue disease corroborating the clinical heterogeneity
AbstractObjectives. To stratify patients with mixed connective tissue disease (MCTD) based on their immunophenotype.Method...
Transcriptomic profiling of osteoarthritis synovial macrophages reveals a tolerized phenotype compounded by a weak corticosteroid response
Transcriptomic profiling of osteoarthritis synovial macrophages reveals a tolerized phenotype compounded by a weak corticosteroid response
AbstractObjectives. It is well-known that long-term osteoarthritis prognosis is not improved by corticosteroid treatments....
Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis—a prospective cohort study
Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis—a prospective cohort study
AbstractObjective. Individuals positive for anti-cyclic-peptide-antibodies (anti-CCP) and musculoskeletal complaints (MSK-...
A simple, clinically usable whole-body MRI system of joint assessment in adolescents and young people with juvenile idiopathic arthritis
A simple, clinically usable whole-body MRI system of joint assessment in adolescents and young people with juvenile idiopathic arthritis
AbstractObjectives. To introduce and evaluate a simple method for assessing joint inflammation and structural damage on wh...
Remote monitoring of patients with rheumatoid arthritis: a mixed methods evaluation across six hospitals in London, UK
Remote monitoring of patients with rheumatoid arthritis: a mixed methods evaluation across six hospitals in London, UK
AbstractObjectives. This study evaluated the scale-up of a remote monitoring (RM) service, capturing monthly Rheumatoid Ar...
Epigenetic changes in inflammatory arthritis monocytes contribute to disease and can be targeted by JAK inhibition
Epigenetic changes in inflammatory arthritis monocytes contribute to disease and can be targeted by JAK inhibition
AbstractObjectives. How the local inflammatory environment regulates epigenetic changes in the context of inflammatory art...
Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis
AbstractObjective. To gain insight in the expression profile of long non-coding RNAs in osteoarthritis (OA) subchondral bo...
Efficacy and safety of secukinumab in patients with spondyloarthritis and enthesitis at the Achilles tendon: Results from a Phase 3b trial
AbstractObjective. ACHILLES aimed to demonstrate efficacy of secukinumab on Achilles’ tendon enthesitis in spondyloarthrit...
Neuropsychiatric systemic lupus erythematosus is associated with a distinct type and shape of cerebral white matter hyperintensities
AbstractOBJECTIVES. Advanced white matter hyperintensity (WMH) markers on brain MRI may help reveal underlying mechanisms ...
Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in Giant Cell Arteritis
AbstractObjectives. Giant Cell Arteritis (GCA) is a large vessel vasculitis in which metabolically active immune cells pla...
Telemedicine in rheumatology: A mixed methods study exploring acceptability, preferences and experiences among patients and clinicians
AbstractObjectives. The Covid-19 pandemic necessitated a rapid global transition towards telemedicine; yet much remains un...