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The History of the Microscope Reflects Advances in Science and Medicine
The History of the Microscope Reflects Advances in Science and Medicine
The history of medical science is intricately linked to the history of microscopy.1 What a ride it has been! The historian...
Mimickers of Immunoglobulin G4-related Hepatobiliary Disease on Biopsy
Mimickers of Immunoglobulin G4-related Hepatobiliary Disease on Biopsy
IgG4-related hepatobiliary disease (IgG4-HBD), which encompasses IgG4-related sclerosing cholangitis (IgG4-SC), IgG4-relat...
Birt-Hogg-Dubé syndrome in an overall view: Focus on the clinicopathological prospects in renal tumors
Birt-Hogg-Dubé syndrome in an overall view: Focus on the clinicopathological prospects in renal tumors
Birt-Hogg-Dube syndrome (BHD) was first described in 1977, characterized as dome-shaped small tumors primarily in the face...
Mark Wick contributions to pathology of the mediastinum
Mark Wick contributions to pathology of the mediastinum
Whereas the eclectic contributions of Dr Mark Wick cover the entirely field of pathology and are dizzying in quantity and ...
Pathology of Hereditary Renal Cell Carcinoma Syndromes
Pathology of Hereditary Renal Cell Carcinoma Syndromes
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Contributions of Dr. Wick to the pathology of diseases of the lung and pleura.
Contributions of Dr. Wick to the pathology of diseases of the lung and pleura.
The world of surgical pathology is rapidly changing, and we are amid a transition between one era and another. The time of...
Clinical-pathologic Correlation: The Impact of Grossing at the Bedside
Clinical-pathologic Correlation: The Impact of Grossing at the Bedside
Available online 5 January 2024Author links open overlay panel, , , , , AbstractThe unenlightened clinician may submit a s...
IgG4-related lymphadenopathy
IgG4-related lymphadenopathy
IgG4-related lymphadenopathy is a nodal manifestation of IgG4-related disease (IgG4RD) most frequently affecting the regio...
Autoimmune pancreatitis: Biopsy interpretation and differential diagnosis
Autoimmune pancreatitis: Biopsy interpretation and differential diagnosis
Available online 3 January 2024Author links open overlay panelABSTRACTAutoimmune pancreatitis (AIP) is classified into typ...
Unraveling the Complexities of IgG4-Related Disease: Musings from a Histopathologist
Unraveling the Complexities of IgG4-Related Disease: Musings from a Histopathologist
Editor, Seminars in Diagnostic Pathology,I have no conflicts of interest to disclose. This encompasses all potential confl...
Advancements in Diagnosing IgG4-Related Disease of the Head and Neck: Navigating Diagnostic Pitfalls
Advancements in Diagnosing IgG4-Related Disease of the Head and Neck: Navigating Diagnostic Pitfalls
IgG4-related disease (IgG4-RD) presents a diagnostic challenge due to its varied symptoms, lack of specific tests, and sym...
IgG4-Related Kidney Disease: Clinicopathologic Features, Differential Diagnosis, and Mimics
IgG4-Related Kidney Disease: Clinicopathologic Features, Differential Diagnosis, and Mimics
In diagnosing medical kidney disease, the renal pathologist evaluates the different “compartments” of the kidney: glomerul...
Hereditary Papillary Renal Cell Carcinoma
Hereditary Papillary Renal Cell Carcinoma
Hereditary papillary renal cell carcinoma (HPRCC) is an autosomal dominant syndrome characterized by the occurrence of bil...
Kidney Cancer: Links between Hereditary Syndromes and Sporadic Tumorigenesis
Kidney Cancer: Links between Hereditary Syndromes and Sporadic Tumorigenesis
Renal cell carcinoma (RCC) is a diverse group of cancers originating from renal tubular epithelial cells and ranks among t...
Updates on lymphoblastic leukemia/lymphoma classification and minimal/measurable residual disease analysis
Updates on lymphoblastic leukemia/lymphoma classification and minimal/measurable residual disease analysis
Lymphoblastic leukemia/lymphoma (ALL/LBL) is a genetically heterogenous group of hematologic malignancies affecting both p...
von Hippel–Lindau Disease-Related Neoplasia with an Emphasis on Renal Manifestations
von Hippel–Lindau Disease-Related Neoplasia with an Emphasis on Renal Manifestations
von Hippel–Lindau (VHL) disease is a hereditary tumor susceptibility syndrome which was initially described by Dr. Eugen v...
Hereditary Succinate Dehydrogenase-deficient Renal Cell Carcinoma
Hereditary Succinate Dehydrogenase-deficient Renal Cell Carcinoma
Succinate dehydrogenase (SDH), also known as mitochondrial complex II, is an enzyme complex located on the inner mitochond...
Diagnostic Work-up of Hematological Malignancies with Underlying Germline Predisposition Disorders (GPD)
Diagnostic Work-up of Hematological Malignancies with Underlying Germline Predisposition Disorders (GPD)
Since the formal recognition of hematological malignancies with GPDs under the diagnostic classification systems, the list...
Differential Diagnosis of IgG4-Positive Plasma Cells in the Lung
Differential Diagnosis of IgG4-Positive Plasma Cells in the Lung
Available online 15 November 2023Author links open overlay panelABSTRACTThe recognition of immunoglobulin G4-related disea...
CHALLENGES AND PITFALLS IN THE DIAGNOSIS OF IgG4-RELATED DISEASE
CHALLENGES AND PITFALLS IN THE DIAGNOSIS OF IgG4-RELATED DISEASE
Available online 15 November 2023Author links open overlay panel, ABSTRACTIgG4-related disease (IgG4-RD) is a relatively n...
Pathology of Hereditary Renal Cell Carcinoma Syndromes: Tuberous Sclerosis Complex (TSC)
Pathology of Hereditary Renal Cell Carcinoma Syndromes: Tuberous Sclerosis Complex (TSC)
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic syndrome that was first described >150 years ago.1,2 ...
Post-transplant Lymphoproliferative Disorders (PTLD) in Adolescents and Young Adults: A Category in Need of Definition
Post-transplant lymphoproliferative disorders (PTLDs) are a well-recognized complication of solid organ (SOT) and stem cel...
A personalized approach to lymphoproliferations in patients with inborn errors of immunity
The International Union of Immunological Societies (IUIS) divides the inborn errors of immunity (IEI) to ten categories1.S...
Classic Hodgkin lymphoma in young people
The distinctive combination of clinical and pathological features associated with classic Hodgkin lymphoma (CHL) helped ma...
Small Biopsies in the Head and Neck: Bone and Soft Tissue
Statistically, the most common spindle cell tumors of apparent dermal or mucosal origin are not of mesenchymal lineage but...
Inherited bone marrow failure syndromes and germline predisposition to myeloid neoplasia: a practical approach for the pathologist
The diagnostic work up and surveillance of germline disorders of bone marrow failure (BMF) and predisposition to myeloid m...
Approach to Small Biopsies in the Larynx
Small biopsies can present diagnostic challenges to the surgical pathologist. The lack of wider architecture can limit int...
The Many Faces of Atypical Fibroxanthoma
Atypical fibroxanthoma (AFX) is a rare primary skin neoplasm of presumable mesenchymal derivation but of uncertain histoge...
Aggressive non-Hodgkin lymphoma in the pediatric and young adult population; diagnostic and molecular pearls of wisdom.
Available online 22 June 2023Author links open overlay panel, ABSTRACTMature non-Hodgkin lymphomas (NHLs) of the pediatric...