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SPECT-MPI iterative denoising during the reconstruction process using a two-phase learned convolutional neural network
SPECT-MPI iterative denoising during the reconstruction process using a two-phase learned convolutional neural network
The problem of image denoising in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is...
PET radiomics in lung cancer: advances and translational challenges
PET radiomics in lung cancer: advances and translational challenges
Radiomics is an emerging field of medical imaging that aims at improving the accuracy of diagnosis, prognosis, treatment p...
Deep learning-based multi-frequency denoising for myocardial perfusion SPECT
Deep learning-based multi-frequency denoising for myocardial perfusion SPECT
Deep learning (DL)-based denoising has been proven to improve image quality and quantitation accuracy of low dose (LD) SPE...
Accuracy of holmium-166 SPECT/CT quantification over a large range of activities
Accuracy of holmium-166 SPECT/CT quantification over a large range of activities
Quantitative imaging is a crucial step for dosimetry in radionuclide therapies. Traditionally, SPECT/CT imaging is quantif...
Reproducibility of [18F]MK-6240 kinetics in brain studies with shortened dynamic PET protocol in healthy/cognitively normal subjects
Reproducibility of [18F]MK-6240 kinetics in brain studies with shortened dynamic PET protocol in healthy/cognitively normal subjects
[18F]MK-6240 is a neurofibrillary tangles PET radiotracer that has been broadly used in aging and Alzheimer’s diseas...
Quantitative SPECT imaging of 155Tb and 161Tb for preclinical theranostic radiopharmaceutical development
Quantitative SPECT imaging of 155Tb and 161Tb for preclinical theranostic radiopharmaceutical development
Element-equivalent matched theranostic pairs facilitate quantitative in vivo imaging to establish pharmacokinetics and dos...
Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner
Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner
Positron emission tomography (PET) traditionally uses coincident annihilation photons emitted from a positron interacting ...
From SPECT/CT towards absolute quantification? - the case of unilateral condylar hyperplasia of the mandible
From SPECT/CT towards absolute quantification? - the case of unilateral condylar hyperplasia of the mandible
Unilateral condylar hyperplasia (UCH) of the mandible is a rare condition characterized by asymmetric growth of the mandib...
Design and proof of concept of a double-panel TOF-PET system
Design and proof of concept of a double-panel TOF-PET system
Positron Emission Tomography (PET) is a well-known imaging technology for the diagnosis, treatment, and monitoring of seve...
Subtraction of single-photon emission computed tomography (SPECT) in radioembolization: a comparison of four methods
Subtraction of single-photon emission computed tomography (SPECT) in radioembolization: a comparison of four methods
Subtraction of single-photon emission computed tomography (SPECT) images has a number of clinical applications in e.g. foc...
Dosimetric implications of kidney anatomical volume changes in 177Lu-DOTATATE therapy
Dosimetric implications of kidney anatomical volume changes in 177Lu-DOTATATE therapy
This study aims to evaluate the use of CT-based whole kidney parenchyma (WKP) segmentation in 177Lu-DOTATATE dosimetry. Sp...
Automatic reorientation to generate short-axis myocardial PET images
Automatic reorientation to generate short-axis myocardial PET images
Accurately redirecting reconstructed Positron emission tomography (PET) images into short-axis (SA) images shows great sig...
Performance evaluation of the 3D-ring cadmium–zinc–telluride (CZT) StarGuide system according to the NEMA NU 1-2018 standard
Performance evaluation of the 3D-ring cadmium–zinc–telluride (CZT) StarGuide system according to the NEMA NU 1-2018 standard
The application of semi-conductor detectors such as cadmium–zinc–telluride (CZT) in nuclear medicine improves ...
Multi-modal co-learning with attention mechanism for head and neck tumor segmentation on 18FDG PET-CT
Multi-modal co-learning with attention mechanism for head and neck tumor segmentation on 18FDG PET-CT
Effective radiation therapy requires accurate segmentation of head and neck cancer, one of the most common types of cancer...
Estimation of kidney doses from [177Lu]Lu-DOTA-TATE PRRT using single time point post-treatment SPECT/CT
Estimation of kidney doses from [177Lu]Lu-DOTA-TATE PRRT using single time point post-treatment SPECT/CT
Dosimetry after [177Lu]Lu-DOTA-TATE therapy can be demanding for both patients and the clinical service due to the need fo...
Artificial intelligence-based joint attenuation and scatter correction strategies for multi-tracer total-body PET
Artificial intelligence-based joint attenuation and scatter correction strategies for multi-tracer total-body PET
Low-dose ungated CT is commonly used for total-body PET attenuation and scatter correction (ASC). However, CT-based ASC (C...
Deep learning-based measurement of split glomerular filtration rate with 99mTc-diethylenetriamine pentaacetic acid renal scan
Deep learning-based measurement of split glomerular filtration rate with 99mTc-diethylenetriamine pentaacetic acid renal scan
To develop a deep learning (DL) model for generating automated regions of interest (ROIs) on 99mTc-diethylenetriamine pent...
Organ and tumor dosimetry including method simplification for [177Lu]Lu-PSMA-I&T for treatment of metastatic castration resistant prostate cancer
Organ and tumor dosimetry including method simplification for [177Lu]Lu-PSMA-I&T for treatment of metastatic castration resistant prostate cancer
Internal dosimetry in individual patients is essential for safe and effective radioligand therapy. Multiple time point ima...
Timing limits of ultrafast cross-luminescence emission in CsZnCl-based crystals for TOF-CT and TOF-PET
Timing limits of ultrafast cross-luminescence emission in CsZnCl-based crystals for TOF-CT and TOF-PET
Good timing resolution in medical imaging applications such as TOF-CT or TOF-PET can boost image quality or patient comfor...
Deep learning based bilateral filtering for edge-preserving denoising of respiratory-gated PET
Deep learning based bilateral filtering for edge-preserving denoising of respiratory-gated PET
Residual image noise is substantial in positron emission tomography (PET) and one of the factors limiting lesion detection...
Radiomics incorporating deep features for predicting Parkinson’s disease in 123I-Ioflupane SPECT
Radiomics incorporating deep features for predicting Parkinson’s disease in 123I-Ioflupane SPECT
123I-Ioflupane SPECT is an effective tool for the diagnosis and progression assessment of Parkinson’s disease (PD). ...
Pareto optimization of SPECT acquisition and reconstruction settings for 177Lu activity quantification
Pareto optimization of SPECT acquisition and reconstruction settings for 177Lu activity quantification
The aim was to investigate the noise and bias properties of quantitative 177Lu-SPECT with respect to the number of project...
Improvements of 177Lu SPECT images from sparsely acquired projections by reconstruction with deep-learning-generated synthetic projections
Improvements of 177Lu SPECT images from sparsely acquired projections by reconstruction with deep-learning-generated synthetic projections
For dosimetry, the demand for whole-body SPECT/CT imaging, which require long acquisition durations with dual-head Anger c...
Position dependence of recovery coefficients in 177Lu-SPECT/CT reconstructions – phantom simulations and measurements
Position dependence of recovery coefficients in 177Lu-SPECT/CT reconstructions – phantom simulations and measurements
Although the importance of quantitative SPECT has increased tremendously due to newly developed therapeutic radiopharmaceu...
DosePatch: physics-inspired cropping layout for patch-based Monte Carlo simulations to provide fast and accurate internal dosimetry
DosePatch: physics-inspired cropping layout for patch-based Monte Carlo simulations to provide fast and accurate internal dosimetry
Dosimetry-based personalized therapy was shown to have clinical benefits e.g. in liver selective internal radiation therap...
Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in r...
Improving diagnostic precision in amyloid brain PET imaging through data-driven motion correction
Improving diagnostic precision in amyloid brain PET imaging through data-driven motion correction
Head motion during brain positron emission tomography (PET)/computed tomography (CT) imaging degrades image quality, resul...
Does consensus contour improve robustness and accuracy in 18F-FDG PET radiomic features?
Does consensus contour improve robustness and accuracy in 18F-FDG PET radiomic features?
The purpose of our study is to validate the robustness and accuracy of consensus contour in 2-deoxy-2-[ $$^$$ F]fluoro-D-g...