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Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model
Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model
There is an unmet need for prediction of treatment outcome or patient selection for [177Lu]Lu-PSMA therapy in patients wit...
Joint EURADOS-EANM initiative for an advanced computational framework for the assessment of external dose rates from nuclear medicine patients
Joint EURADOS-EANM initiative for an advanced computational framework for the assessment of external dose rates from nuclear medicine patients
In order to ensure adequate radiation protection of critical groups such as staff, caregivers and the general public comin...
Phantom and clinical evaluation of the Bayesian penalised likelihood reconstruction algorithm Q.Clear without PSF correction in amyloid PET images
Phantom and clinical evaluation of the Bayesian penalised likelihood reconstruction algorithm Q.Clear without PSF correction in amyloid PET images
Bayesian penalised likelihood (BPL) reconstruction, which incorporates point-spread-function (PSF) correction, provides hi...
Extended MRI-based PET motion correction for cardiac PET/MRI
Extended MRI-based PET motion correction for cardiac PET/MRI
A 2D image navigator (iNAV) based 3D whole-heart sequence has been used to perform MRI and PET non-rigid respiratory motio...
Gamma camera imaging characteristics of 166Ho and 99mTc used in Selective Internal Radiation Therapy
Gamma camera imaging characteristics of 166Ho and 99mTc used in Selective Internal Radiation Therapy
The administration of a 166Ho scout dose is available as an alternative to 99mTc particles for pre-treatment imaging in Se...
Bone marrow dosimetry in low volume mHSPC patients receiving Lu-177-PSMA therapy using SPECT/CT
Bone marrow dosimetry in low volume mHSPC patients receiving Lu-177-PSMA therapy using SPECT/CT
Bone marrow toxicity in advanced prostate cancer patients who receive [177Lu]Lu-PSMA-617 is a well-known concern. In early...
Impact of scatter correction on personalized dosimetry in selective internal radiotherapy using 166Ho-PLLA: a single-center study including Monte-Carlo simulation, phantom and patient imaging
Impact of scatter correction on personalized dosimetry in selective internal radiotherapy using 166Ho-PLLA: a single-center study including Monte-Carlo simulation, phantom and patient imaging
Developments in transarterial radioembolization led to the conception of new microspheres loaded with holmium-166 (166Ho)....
Impact of different models based on blood samples and images for bone marrow dosimetry after 177Lu-labeled somatostatin-receptor therapy
Impact of different models based on blood samples and images for bone marrow dosimetry after 177Lu-labeled somatostatin-receptor therapy
Peptide receptor radionuclide therapy with 177Lu-DOTATATE is a recognized option for treating neuroendocrine tumors and ha...
Optimising total knee replacement imaging: a novel 3D printed PET/CT anthropomorphic phantom for metal artefact simulation
Optimising total knee replacement imaging: a novel 3D printed PET/CT anthropomorphic phantom for metal artefact simulation
Arthroplasty phantoms, including total knee replacement (TKR) phantoms, have been frequently used to test metal artefact r...
Comparison of a 3D CZT and conventional SPECT/CT system for quantitative Lu-177 SPECT imaging
Comparison of a 3D CZT and conventional SPECT/CT system for quantitative Lu-177 SPECT imaging
Next-generation SPECT/CT systems with CdZnTe (CZT) digital detectors in a ring-like setup are emerging to perform quantita...
Assessment of the axial resolution of a compact gamma camera with coded aperture collimator
Assessment of the axial resolution of a compact gamma camera with coded aperture collimator
Handheld gamma cameras with coded aperture collimators are under investigation for intraoperative imaging in nuclear medic...
Sequential deep learning image enhancement models improve diagnostic confidence, lesion detectability, and image reconstruction time in PET
Sequential deep learning image enhancement models improve diagnostic confidence, lesion detectability, and image reconstruction time in PET
Investigate the potential benefits of sequential deployment of two deep learning (DL) algorithms namely DL-Enhancement (DL...
155Tb production by cyclotrons: what level of 155Gd enrichment allows clinical applications?
155Tb production by cyclotrons: what level of 155Gd enrichment allows clinical applications?
155Tb represents a potentially useful radionuclide for diagnostic medical applications, but its production remains a chall...
Reduction of [68Ga]Ga-DOTA-TATE injected activity for digital PET/MR in comparison with analogue PET/CT
Reduction of [68Ga]Ga-DOTA-TATE injected activity for digital PET/MR in comparison with analogue PET/CT
New digital detectors and block-sequential regularized expectation maximization (BSREM) reconstruction algorithm improve p...
Validation of image-derived input function using a long axial field of view PET/CT scanner for two different tracers
Validation of image-derived input function using a long axial field of view PET/CT scanner for two different tracers
Accurate image-derived input function (IDIF) from highly sensitive large axial field of view (LAFOV) PET/CT scanners could...
Development and validation of a prognostic nomogram model in locally advanced NSCLC based on metabolic features of PET/CT and hematological inflammatory indicators
Development and validation of a prognostic nomogram model in locally advanced NSCLC based on metabolic features of PET/CT and hematological inflammatory indicators
We combined the metabolic features of 18F-FDG-PET/CT and hematological inflammatory indicators to establish a predictive m...
Clinical feasibility study of early 30-minute dynamic FDG-PET scanning protocol for patients with lung lesions
Clinical feasibility study of early 30-minute dynamic FDG-PET scanning protocol for patients with lung lesions
This study aimed to evaluate the clinical feasibility of early 30-minute dynamic 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG)...
Effect of kilovoltage and quality reference mAs on CT-based attenuation correction in 177Lu SPECT/CT imaging: a phantom study
Effect of kilovoltage and quality reference mAs on CT-based attenuation correction in 177Lu SPECT/CT imaging: a phantom study
CT-based attenuation correction (CT-AC) plays a major role in accurate activity quantification by SPECT/CT imaging. Howeve...
Kinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a dual input four-compartment model
Kinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a dual input four-compartment model
The endoplasmic reticulum plays an important role in glucose metabolism and has not been explored in the kinetic estimatio...
Fit of biokinetic data in molecular radiotherapy: a machine learning approach
Fit of biokinetic data in molecular radiotherapy: a machine learning approach
In literature are reported different analytical methods (AM) to choose the proper fit model and to fit data of the time-ac...
Quantitative calibration of Tb-161 SPECT/CT in view of personalised dosimetry assessment studies
Quantitative calibration of Tb-161 SPECT/CT in view of personalised dosimetry assessment studies
Terbium-161 (161Tb)-based radionuclide therapy poses an alternative to current Lutetium-177 (177Lu) approaches with the ad...
Phantom study and clinical application of total-body 18F-FDG PET/CT imaging: How to use small voxel imaging better?
Phantom study and clinical application of total-body 18F-FDG PET/CT imaging: How to use small voxel imaging better?
Conventional PET/CT imaging reconstruction is typically performed using voxel size of 3.0–4.0 mm in three a...
How to obtain the image-derived blood concentration from 89Zr-immuno-PET scans
How to obtain the image-derived blood concentration from 89Zr-immuno-PET scans
PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure upt...
Anatomy-based correction of kidney PVE on \(^{177}\text{Lu}\) SPECT images
Anatomy-based correction of kidney PVE on \(^{177}\text{Lu}\) SPECT images
In peptide receptor radionuclide therapy (PRRT), accurate quantification of kidney activity on post-treatment SPECT images...
Prediction of [177Lu]Lu-DOTA-TATE therapy response using the absorbed dose estimated from [177Lu]Lu-DOTA-TATE SPECT/CT in patients with metastatic neuroendocrine tumour
Prediction of [177Lu]Lu-DOTA-TATE therapy response using the absorbed dose estimated from [177Lu]Lu-DOTA-TATE SPECT/CT in patients with metastatic neuroendocrine tumour
Peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu-DOTA-TATE has shown efficacy in patients with metastatic neuro...
Validation of a discovery MI 4-ring model according to the NEMA NU 2-2018 standards: from Monte Carlo simulations to clinical-like reconstructions
Validation of a discovery MI 4-ring model according to the NEMA NU 2-2018 standards: from Monte Carlo simulations to clinical-like reconstructions
We propose a comprehensive evaluation of a Discovery MI 4-ring (DMI) model, using a Monte Carlo simulator (GATE) and a cli...
Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography
Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography
Pharmacokinetic positron emission tomography (PET) studies rely on the measurement of the arterial input function (AIF), w...
Simultaneous estimation of a model-derived input function for quantifying cerebral glucose metabolism with [18F]FDG PET
Simultaneous estimation of a model-derived input function for quantifying cerebral glucose metabolism with [18F]FDG PET
Quantification of the cerebral metabolic rate of glucose (CMRGlu) by dynamic [18F]FDG PET requires invasive arterial sampl...
Evaluating a radiotherapy deep learning synthetic CT algorithm for PET-MR attenuation correction in the pelvis
Evaluating a radiotherapy deep learning synthetic CT algorithm for PET-MR attenuation correction in the pelvis
Positron emission tomography–magnetic resonance (PET-MR) attenuation correction is challenging because the MR signal...
Insertion of synthetic lesions on patient data: a method for evaluating clinical performance differences between PET systems
Insertion of synthetic lesions on patient data: a method for evaluating clinical performance differences between PET systems
Performance assessment of positron emission tomography (PET) scanners is crucial to guide clinical practice with efficienc...
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