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How much do 68Ga-, 177Lu- and 131I-based radiopharmaceuticals contribute to the global radiation exposure of nuclear medicine staff?
How much do 68Ga-, 177Lu- and 131I-based radiopharmaceuticals contribute to the global radiation exposure of nuclear medicine staff?
The radiation exposure of nuclear medicine personnel, especially concerning extremity doses, has been a significant focus ...
Optimization and application of renal depth measurement method in the cadmium-zinc-telluride‑based SPECT/CT renal dynamic imaging
Optimization and application of renal depth measurement method in the cadmium-zinc-telluride‑based SPECT/CT renal dynamic imaging
This study aims to evaluate the accuracy of four kidney depth measurement methods—nuclear medicine tomography, nucle...
Comparison of the dosimetry and cell survival effect of 177Lu and 161Tb somatostatin analog radiopharmaceuticals in cancer cell clusters and micrometastases
Comparison of the dosimetry and cell survival effect of 177Lu and 161Tb somatostatin analog radiopharmaceuticals in cancer cell clusters and micrometastases
177Lu-based radiopharmaceuticals (RPs) are the most used for targeted radionuclide therapy (TRT) due to their good respons...
Partial volume correction for Lu-177-PSMA SPECT
Partial volume correction for Lu-177-PSMA SPECT
The limited spatial resolution in SPECT images leads to partial volume effect (PVE), degrading the subsequent dosimetric a...
Bidirectional dynamic frame prediction network for total-body [68Ga]Ga-PSMA-11 and [68Ga]Ga-FAPI-04 PET images
Bidirectional dynamic frame prediction network for total-body [68Ga]Ga-PSMA-11 and [68Ga]Ga-FAPI-04 PET images
Total-body dynamic positron emission tomography (PET) imaging with total-body coverage and ultrahigh sensitivity has playe...
Development of quantitative PET/MR imaging for measurements of hepatic portal vein input function: a phantom study
Development of quantitative PET/MR imaging for measurements of hepatic portal vein input function: a phantom study
Accurate pharmacokinetic modelling in PET necessitates measurements of an input function, which ideally is acquired non-in...
Bias and precision of SPECT-based 177Lu activity-concentration estimation using a ring-configured solid-state versus a dual-headed anger system
Bias and precision of SPECT-based 177Lu activity-concentration estimation using a ring-configured solid-state versus a dual-headed anger system
The aim was to compare bias and precision for 177Lu-SPECT activity-concentration estimation using a dual-headed Anger SPEC...
360° CZT-SPECT/CT cameras: 99mTc- and 177Lu-phantom-based evaluation under clinical conditions
360° CZT-SPECT/CT cameras: 99mTc- and 177Lu-phantom-based evaluation under clinical conditions
For the first time, three currently available 360° CZT-SPECT/CT cameras were compared under clinical conditions using...
Development and validation of an innovative administration system to facilitate controlled holmium-166 microsphere administration during TARE
Development and validation of an innovative administration system to facilitate controlled holmium-166 microsphere administration during TARE
To develop and validate a novel administration device for holmium-166 transarterial radioembolisation (TARE) with the purp...
Assessing the deep learning based image quality enhancements for the BGO based GE omni legend PET/CT
Assessing the deep learning based image quality enhancements for the BGO based GE omni legend PET/CT
This study investigates the integration of Artificial Intelligence (AI) in compensating the lack of time-of-flight (TOF) o...
Method for co-registration of high-resolution specimen PET-CT with histopathology to improve insight into radiotracer distributions
Method for co-registration of high-resolution specimen PET-CT with histopathology to improve insight into radiotracer distributions
As the spatial resolution of positron emission tomography (PET) scanners improves, understanding of radiotracer distributi...
Deep-learning-based attenuation map generation in kidney single photon emission computed tomography
Deep-learning-based attenuation map generation in kidney single photon emission computed tomography
Accurate attenuation correction (AC) is vital in nuclear medicine, particularly for quantitative single-photon emission co...
Feasibility of shortening scan duration of 18F-FDG myocardial metabolism imaging using a total-body PET/CT scanner
Feasibility of shortening scan duration of 18F-FDG myocardial metabolism imaging using a total-body PET/CT scanner
To evaluate 18F-FDG myocardial metabolism imaging (MMI) using a total-body PET/CT scanner and explore the feasible scan du...
SPECT-MPI iterative denoising during the reconstruction process using a two-phase learned convolutional neural network
SPECT-MPI iterative denoising during the reconstruction process using a two-phase learned convolutional neural network
The problem of image denoising in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is...
PET radiomics in lung cancer: advances and translational challenges
PET radiomics in lung cancer: advances and translational challenges
Radiomics is an emerging field of medical imaging that aims at improving the accuracy of diagnosis, prognosis, treatment p...
Deep learning-based multi-frequency denoising for myocardial perfusion SPECT
Deep learning-based multi-frequency denoising for myocardial perfusion SPECT
Deep learning (DL)-based denoising has been proven to improve image quality and quantitation accuracy of low dose (LD) SPE...
Accuracy of holmium-166 SPECT/CT quantification over a large range of activities
Accuracy of holmium-166 SPECT/CT quantification over a large range of activities
Quantitative imaging is a crucial step for dosimetry in radionuclide therapies. Traditionally, SPECT/CT imaging is quantif...
Reproducibility of [18F]MK-6240 kinetics in brain studies with shortened dynamic PET protocol in healthy/cognitively normal subjects
Reproducibility of [18F]MK-6240 kinetics in brain studies with shortened dynamic PET protocol in healthy/cognitively normal subjects
[18F]MK-6240 is a neurofibrillary tangles PET radiotracer that has been broadly used in aging and Alzheimer’s diseas...
Quantitative SPECT imaging of 155Tb and 161Tb for preclinical theranostic radiopharmaceutical development
Quantitative SPECT imaging of 155Tb and 161Tb for preclinical theranostic radiopharmaceutical development
Element-equivalent matched theranostic pairs facilitate quantitative in vivo imaging to establish pharmacokinetics and dos...
Feasibility of a deep-inspiration breath-hold [18F]AlF-NOTA-LM3 PET/CT imaging on upper-abdominal lesions in NET patients: in comparison with respiratory-gated PET/CT
Feasibility of a deep-inspiration breath-hold [18F]AlF-NOTA-LM3 PET/CT imaging on upper-abdominal lesions in NET patients: in comparison with respiratory-gated PET/CT
To explore the clinical feasibility and efficacy of a deep inspiration breath-hold (BH) PET/CT using [18F]AlF-NOTA-LM3 on ...
Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner
Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner
Positron emission tomography (PET) traditionally uses coincident annihilation photons emitted from a positron interacting ...
From SPECT/CT towards absolute quantification? - the case of unilateral condylar hyperplasia of the mandible
From SPECT/CT towards absolute quantification? - the case of unilateral condylar hyperplasia of the mandible
Unilateral condylar hyperplasia (UCH) of the mandible is a rare condition characterized by asymmetric growth of the mandib...
Design and proof of concept of a double-panel TOF-PET system
Design and proof of concept of a double-panel TOF-PET system
Positron Emission Tomography (PET) is a well-known imaging technology for the diagnosis, treatment, and monitoring of seve...
Subtraction of single-photon emission computed tomography (SPECT) in radioembolization: a comparison of four methods
Subtraction of single-photon emission computed tomography (SPECT) in radioembolization: a comparison of four methods
Subtraction of single-photon emission computed tomography (SPECT) images has a number of clinical applications in e.g. foc...
Dosimetric implications of kidney anatomical volume changes in 177Lu-DOTATATE therapy
Dosimetric implications of kidney anatomical volume changes in 177Lu-DOTATATE therapy
This study aims to evaluate the use of CT-based whole kidney parenchyma (WKP) segmentation in 177Lu-DOTATATE dosimetry. Sp...
Automatic reorientation to generate short-axis myocardial PET images
Automatic reorientation to generate short-axis myocardial PET images
Accurately redirecting reconstructed Positron emission tomography (PET) images into short-axis (SA) images shows great sig...
Performance evaluation of the 3D-ring cadmium–zinc–telluride (CZT) StarGuide system according to the NEMA NU 1-2018 standard
Performance evaluation of the 3D-ring cadmium–zinc–telluride (CZT) StarGuide system according to the NEMA NU 1-2018 standard
The application of semi-conductor detectors such as cadmium–zinc–telluride (CZT) in nuclear medicine improves ...
Multi-modal co-learning with attention mechanism for head and neck tumor segmentation on 18FDG PET-CT
Multi-modal co-learning with attention mechanism for head and neck tumor segmentation on 18FDG PET-CT
Effective radiation therapy requires accurate segmentation of head and neck cancer, one of the most common types of cancer...
Estimation of kidney doses from [177Lu]Lu-DOTA-TATE PRRT using single time point post-treatment SPECT/CT
Estimation of kidney doses from [177Lu]Lu-DOTA-TATE PRRT using single time point post-treatment SPECT/CT
Dosimetry after [177Lu]Lu-DOTA-TATE therapy can be demanding for both patients and the clinical service due to the need fo...
Artificial intelligence-based joint attenuation and scatter correction strategies for multi-tracer total-body PET
Artificial intelligence-based joint attenuation and scatter correction strategies for multi-tracer total-body PET
Low-dose ungated CT is commonly used for total-body PET attenuation and scatter correction (ASC). However, CT-based ASC (C...
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