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Light-assisted functionalization of aryl radicals towards metal-free cross-coupling
Light-assisted functionalization of aryl radicals towards metal-free cross-coupling
The many synthetic possibilities that arise when using radical intermediates, in place of their polar counterparts, make c...
A career with an eye to the sky
A career with an eye to the sky
Ahead of his 75th birthday, A. R. (Ravi) Ravishankara, Professor in the Departments of Chemistry and Atmospheric Science a...
Cracking the triple helix
Cracking the triple helix
A novel method to detect proteins interacting with triplex DNA in living cells has been developed. This approach provides ...
Presenting the tactile periodic table
Presenting the tactile periodic table
Through the collaboration of two members of the ACS Committee on Chemists with Disabilities, a prototype Braille periodic ...
Mixing metals with MXenes
Mixing metals with MXenes
Metal/MXene composites are a combination of metals with highly conductive MXenes that results in an enhanced functionality...
Low-energy photoredox catalysis
Low-energy photoredox catalysis
With the advent of photoredox catalysis, new synthetic paradigms have been established with many novel transformations bei...
Exploring the boundaries of covalency
Exploring the boundaries of covalency
One electron σ-bonds were first proposed in 1931 but most discussion since then has been at a theoretical level. The ...
Smart molecular designs and applications of activatable organic photosensitizers
Smart molecular designs and applications of activatable organic photosensitizers
Photodynamic therapy (PDT) — which combines light, oxygen and photosensitizers (PS) to generate reactive oxygen spec...
Holding your nerve in academia whilst managing multiple sclerosis
Holding your nerve in academia whilst managing multiple sclerosis
Multiple sclerosis (MS) is a degenerative disease of the central nervous system. Two early-career researchers in supramole...
Assembling a new generation of radiopharmaceuticals with supramolecular theranostics
Assembling a new generation of radiopharmaceuticals with supramolecular theranostics
Supramolecular chemistry has been used to tackle some of the major challenges in modern science, including cancer therapy ...
Green rust for green chemistry
Green rust for green chemistry
A new study explores the catalytic potential of green rust for selectively converting carbon monoxide (CO) to acetone with...
An algorithmic looking glass for transitions
An algorithmic looking glass for transitions
Glass transition temperatures are determined through, for instance, calorimetry, but maybe machine learning models can pre...
Understanding the chemistry of mesostructured porous nanoreactors
Understanding the chemistry of mesostructured porous nanoreactors
Porous nanoreactors mimic the structures and functions of cells, providing an adaptable material with multiple functions a...
Reflections on a Nobel Prize-winning legacy
Reflections on a Nobel Prize-winning legacy
Ahead of his 80th birthday, Jean-Pierre Sauvage discussed his career in science from a lab in his cellar to the Nobel Priz...
Reprogramming the genetic code with flexizymes
Reprogramming the genetic code with flexizymes
In the canonical genetic code, the 61 sense codons are assigned to the 20 proteinogenic amino acids. Advancements in genet...
Asymmetric phase-transfer catalysis
Asymmetric phase-transfer catalysis
Over the past three decades, chiral phase-transfer catalysts (PTCs) have emerged as highly successful organocatalysts in a...
2D magnets filled with lithium
2D magnets filled with lithium
Room-temperature magnetism is challenging for 2D materials as they tend to lose their magnetic order at increasing tempera...
Accessing monomers from lignin through carbon–carbon bond cleavage
Accessing monomers from lignin through carbon–carbon bond cleavage
Lignin, the heterogeneous aromatic macromolecule found in the cell walls of vascular plants, is an abundant feedstock for ...
Ni-catalysed remote C(sp3)–H functionalization using chain-walking strategies
Ni-catalysed remote C(sp3)–H functionalization using chain-walking strategies
The dynamic translocation of a metal catalyst along an alkyl side chain — often coined as ‘chain-walking’...
Secrets from a spin-out success story
Secrets from a spin-out success story
Ahead of his 85th birthday, Graham Richards discussed his life in science and its intersection with industry. From a mix-u...
On the aqueous origins of the condensation polymers of life
On the aqueous origins of the condensation polymers of life
Water is essential for life as we know it, but it has paradoxically been considered inimical to the emergence of life. Pro...
A zwitterionic twist
A zwitterionic twist
An mRNA sequence that encodes a zwitterionic polypeptide fused to a therapeutic protein improves the pharmacokinetic prope...
Reviving antibiotic power
Reviving antibiotic power
Inhibiting a signal transducer, which kicks off the production of β-lactamase in response to the presence of an antib...
The Not Voodoo website after twenty dynamic years
The Not Voodoo website after twenty dynamic years
2024 marks twenty years of the educational website Not Voodoo: Demystifying Synthetic Organic Chemistry — a fount of...
The current utility and future potential of multiborylated alkanes
The current utility and future potential of multiborylated alkanes
Organoboron chemistry has become a cornerstone of modern synthetic methodology. Most of these reactions use an organoboron...
Student partnerships for sustainable change
Strong partnerships with students are critical to curriculum development and research. This can foster a culture of contin...
Organic chemistry for kids
Organic chemistry for kids
Chem Kids is a science camp where children ages 10 to 12 years old learn the notoriously difficult subject of org...
Molecular complexity as a driving force for the advancement of organic synthesis
Molecular complexity as a driving force for the advancement of organic synthesis
The generation of molecular complexity is a primary goal in the field of synthetic chemistry. In the context of retrosynth...
Conformational control over proton-coupled electron transfer in metalloenzymes
Conformational control over proton-coupled electron transfer in metalloenzymes
From the reduction of dinitrogen to the oxidation of water, the chemical transformations catalysed by metalloenzy...
Non-equilibrium self-assembly for living matter-like properties
Non-equilibrium self-assembly for living matter-like properties
The soft and wet machines of life emerged as the spatially enclosed ensemble of biomolecules with replicating capabilities...