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Association among the number of natural teeth, dental maintenance visits and diabetes status: a cross-sectional study using employment-based healthcare claims database
Association among the number of natural teeth, dental maintenance visits and diabetes status: a cross-sectional study using employment-based healthcare claims database
Although diabetes is associated with the risk of tooth loss, there are no large-scale studies examining the reality and th...
Case-based learning: a case of maturity-onset diabetes of the young 5 (MODY5) due to 17q12 microdeletion with a diminished plasma glucagon level
Case-based learning: a case of maturity-onset diabetes of the young 5 (MODY5) due to 17q12 microdeletion with a diminished plasma glucagon level
Maturity-onset diabetes of the young type 5 (MODY5), causally associated with loss-of-function of the HNF1B gene, is a rar...
Sitagliptin, diabetes mellitus, and heart failure: an in-depth review of sitagliptin therapy and heart failure in patients with diabetes mellitus
Sitagliptin, diabetes mellitus, and heart failure: an in-depth review of sitagliptin therapy and heart failure in patients with diabetes mellitus
Heart failure (HF) is characterized by impairments in cardiac function and heart structural changes. Type-2 diabetes melli...
Immune checkpoint inhibitor-related type 1 diabetes mellitus with closely monitored dynamics of glutamic acid decarboxylase antibody levels before and after disease onset
Immune checkpoint inhibitor-related type 1 diabetes mellitus with closely monitored dynamics of glutamic acid decarboxylase antibody levels before and after disease onset
Immune checkpoint inhibitor (ICI)-related type 1 diabetes mellitus (T1DM) is a severe immune-related adverse event (irAE),...
Perception of hyper-/hypoglycemia and its related factors in type 2 diabetes: a continuous glucose monitoring-based prospective observational study
Perception of hyper-/hypoglycemia and its related factors in type 2 diabetes: a continuous glucose monitoring-based prospective observational study
Underestimating hyper-/hypoglycemia or failure to perceive hyperglycemia hinders optimal glucose management in diabetes ca...
Association of metformin administration with the serum levels of zinc and homocysteine in patients with type 2 diabetes: a cross-sectional study
Association of metformin administration with the serum levels of zinc and homocysteine in patients with type 2 diabetes: a cross-sectional study
Metformin treatment has a risk factor of reduced serum concentrations of vitamin B12 and zinc, indicating its association ...
Impact of a COVID-19 emergency declaration on blood glucose levels in individuals with type 1 diabetes treated with a sensor-augmented pump
Impact of a COVID-19 emergency declaration on blood glucose levels in individuals with type 1 diabetes treated with a sensor-augmented pump
COVID-19 emergency declarations and ensuing lockdowns affected lifestyle and glycemic control in individuals with diabetes...
Effect of oral semaglutide on remnant-like lipoprotein cholesterol in patients with ischemic heart disease receiving statin therapy
Effect of oral semaglutide on remnant-like lipoprotein cholesterol in patients with ischemic heart disease receiving statin therapy
High remnant-like lipoprotein (RLP) cholesterolemia has been reported as a risk factor for cardiovascular events in stable...
Glucagon change rate after glucose load: a potential key for tailoring treatment in gestational diabetes mellitus
Glucagon change rate after glucose load: a potential key for tailoring treatment in gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a known risk factor for both maternal and fatal complications. Glycemic control in ...
Job stress evaluated using the brief job stress questionnaire and diabetes mellitus among a Japanese occupational population
Job stress evaluated using the brief job stress questionnaire and diabetes mellitus among a Japanese occupational population
Stress and working environments are risk factors for diabetes mellitus. A new occupational health policy called the Stress...
Relationship of dietary intake and eating behaviors with glycemic control and body weight under long-term treatment with dapagliflozin: an exploratory prospective study
Relationship of dietary intake and eating behaviors with glycemic control and body weight under long-term treatment with dapagliflozin: an exploratory prospective study
Sodium glucose cotransporter-2 (SGLT2) inhibitors improve glycemic control and reduce body weight (BW) in individuals with...
Associations between clustering of hypoglycemic symptoms, psychological traits, and problem-solving abilities in adults with type 1 diabetes: baseline data analysis of the PR-IAH study
Associations between clustering of hypoglycemic symptoms, psychological traits, and problem-solving abilities in adults with type 1 diabetes: baseline data analysis of the PR-IAH study
Precision medicine in diabetes care requires a dedicated focus on hypoglycemic symptoms. This study explored the associati...
Long-term efficacy and safety of early sitagliptin initiation in individuals with type 2 diabetes: an extension of the SPIKE study
Long-term efficacy and safety of early sitagliptin initiation in individuals with type 2 diabetes: an extension of the SPIKE study
We previously demonstrated that sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, slowed down the progression of ca...
Plantar pressure and shear stress during gait in people with diabetic neuropathy
Plantar pressure and shear stress during gait in people with diabetic neuropathy
Diabetic foot ulcers are a leading cause of lower extremity amputations, significantly affecting the quality of life. Exce...
Unraveling the pathophysiology of type 2 diabetes with a new selectively bred animal model, the Oikawa-Nagao mouse
Unraveling the pathophysiology of type 2 diabetes with a new selectively bred animal model, the Oikawa-Nagao mouse
Type 2 diabetes (T2D) is a polygenic disease, and the development of animal models by selective breeding is crucial for un...
Pathophysiological hallmarks in type 2 diabetes heterogeneity (review)
Pathophysiological hallmarks in type 2 diabetes heterogeneity (review)
The mechanistic complexity in type 2 diabetes (T2DM) is primarily responsible for the degrees of heterogeneity and develop...
Long-term effects of esaxerenone in patients with type 2 diabetes, diabetic kidney disease, and hypertension (JDDM77)
Long-term effects of esaxerenone in patients with type 2 diabetes, diabetic kidney disease, and hypertension (JDDM77)
This clinical study assessed the three-year, long-term effects of esaxerenone, a non-steroidal aldosterone receptor blocke...
Regulation of glucose metabolism by incretins: implications for treatment of type 2 diabetes
Regulation of glucose metabolism by incretins: implications for treatment of type 2 diabetes
Gastrointestinal hormones that potentiate insulin secretion from pancreatic β-cells are called incretins. Glucose-dep...
Protective effect of CK2 against endoplasmic reticulum stress in pancreatic β cells
Protective effect of CK2 against endoplasmic reticulum stress in pancreatic β cells
Endoplasmic reticulum (ER) stress due to obesity or systemic insulin resistance is an important pathogenic factor that cou...
Differentiation, reduction, and proliferation of pancreatic β-cells and their regulatory factors
Differentiation, reduction, and proliferation of pancreatic β-cells and their regulatory factors
The prevalence of diabetes has increased rapidly in recent years, and many types of therapeutic agents have been developed...
Glycemic variability and quality of life outcomes after changing to hybrid closed-loop system in Japanese individuals with type 1 diabetes using a conventional predictive low-glucose suspended insulin pump system
Glycemic variability and quality of life outcomes after changing to hybrid closed-loop system in Japanese individuals with type 1 diabetes using a conventional predictive low-glucose suspended insulin pump system
The hybrid closed-loop (HCL) system, Medtronic MiniMed™ 770G, has been available for use by Japanese individuals wit...
Depression in pregnant non-diabetic women and women with gestational diabetes in Bangladesh—a comparative study based on multiple logistic regression
Depression in pregnant non-diabetic women and women with gestational diabetes in Bangladesh—a comparative study based on multiple logistic regression
Depression and gestational diabetes mellitus (GDM) pose significant challenges during pregnancy. Limited literature exists...
Mitochondrial DNA 3243 mutation may be associated with positivity of zinc transporter 8 autoantibody in cases of slowly progressive type 1 diabetes mellitus
Mitochondrial DNA 3243 mutation may be associated with positivity of zinc transporter 8 autoantibody in cases of slowly progressive type 1 diabetes mellitus
Slowly progressive type 1 diabetes mellitus (SPIDDM), solely positive for zinc transporter 8 autoantibody (ZnT8A) is rare,...
Insulin resistant diabetes mellitus in a girl with mild Rabson-Mendenhall syndrome: efficacy of sodium glucose co-transporter 2 inhibitor
Insulin resistant diabetes mellitus in a girl with mild Rabson-Mendenhall syndrome: efficacy of sodium glucose co-transporter 2 inhibitor
We report a beneficial effect of a sodium glucose co-transporter 2 (SGLT2) inhibitor in the management of insulin resistan...
Systemic lupus erythematosus and pulmonary tuberculosis in a patient developing acute-onset type 1 diabetes
Systemic lupus erythematosus and pulmonary tuberculosis in a patient developing acute-onset type 1 diabetes
A 73-year-old Japanese woman was admitted to our hospital with anorexia, weight loss, and fever. A few weeks prior to admi...
Practice guideline: Statement regarding treatment for suspected slowly progressive type 1 diabetes (SPIDDM; probable) cases (English Version)
Practice guideline: Statement regarding treatment for suspected slowly progressive type 1 diabetes (SPIDDM; probable) cases (English Version)
Insulin treatment should be introduced in patients with slowly progressive type 1 diabetes (SPIDDM; definite), according t...
Factors associated with the recurrence of foot ulcers in Japanese patients with diabetes
Factors associated with the recurrence of foot ulcers in Japanese patients with diabetes
Patients with diabetes are frequently complicated with diabetic foot ulcers (DFUs) which are vulnerable to recurrence afte...
Slow progression of type 1 diabetes associated with pembrolizumab and lenvatinib combination therapy in a patient with probable slowly progressive type 1 diabetes mellitus and endometrial cancer
Slow progression of type 1 diabetes associated with pembrolizumab and lenvatinib combination therapy in a patient with probable slowly progressive type 1 diabetes mellitus and endometrial cancer
A 58-year-old woman with a body mass index of 26.4 kg/m2 was referred because of high glycated hemoglobin (HbA1c)...
Prevalence and risk factors for skeletal muscle mass loss in individuals with type 1 diabetes
Prevalence and risk factors for skeletal muscle mass loss in individuals with type 1 diabetes
This study aimed to the investigate prevalence and factors associated with reduced skeletal muscle mass in non-elderly adu...
Blood cell HbA1c measured by enzymatic assay show higher than whole blood HbA1c in patients with iron deficiency anemia
Blood cell HbA1c measured by enzymatic assay show higher than whole blood HbA1c in patients with iron deficiency anemia
In Japan, most HbA1c measurements by enzymatic assays or immunoassays represent the HbA1c levels in the blood cell fractio...
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