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Tackling AKI
Tackling AKI
Cardiovascular Metabolism, Janssen Research and Development LLC, Boston, Massachusetts Correspondence: Dr. Ma...
Sodium Bicarbonate Treatment and Vascular Function in CKD: A Randomized, Double-Blind Placebo Controlled Trial
Sodium Bicarbonate Treatment and Vascular Function in CKD: A Randomized, Double-Blind Placebo Controlled Trial
Background: Lower serum bicarbonate levels, even within the normal range, are strongly linked to
Randomized trial to assess the clinical utility of renal allograft monitoring by urine CXCL10 chemokine
Randomized trial to assess the clinical utility of renal allograft monitoring by urine CXCL10 chemokine
Background: Urine CXCL10 is a promising non-invasive biomarker for detection of renal allograft r
Retrieve, Summarize, and Verify: How will ChatGPT impact information seeking from the medical literature?
Retrieve, Summarize, and Verify: How will ChatGPT impact information seeking from the medical literature?
1National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of H...
Age-Based versus Young-Adult Thresholds for Nephrosclerosis on Kidney Biopsy and Prognostic Implications for Chronic Kidney Disease
Age-Based versus Young-Adult Thresholds for Nephrosclerosis on Kidney Biopsy and Prognostic Implications for Chronic Kidney Disease
Background Nephrosclerosis, defined by globally sclerotic glomeruli (GSG) and interstitial fibros
PCK1 Protects Against Mitoribosomal Defects in Diabetic Nephropathy in Mouse Models
PCK1 Protects Against Mitoribosomal Defects in Diabetic Nephropathy in Mouse Models
Background: Phosphoenolpyruvate carboxykinase (PEPCK) is part of the gluconeogenesis pathway, whi
miR-147 Represses NDUFA4, Inducing Mitochondrial Dysfunction and Tubular Damage in Cold-storage Kidney Transplantation
miR-147 Represses NDUFA4, Inducing Mitochondrial Dysfunction and Tubular Damage in Cold-storage Kidney Transplantation
Background: Kidney injury due to cold storage–associated transplantation (CST) is a major factor
Mirror, Mirror on the Wall: Do Kidney RCT Populations Represent the People We Treat?
Mirror, Mirror on the Wall: Do Kidney RCT Populations Represent the People We Treat?
Department of Kidney Medicine, Cleveland Clinic, Cleveland, Ohio Correspondence: Dr. Crystal A. Gadegbeku Cle...
Kidney-Derived Thrombopoietin and Platelet Generation—A Proinflammatory Loop in CKD
Kidney-Derived Thrombopoietin and Platelet Generation—A Proinflammatory Loop in CKD
Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Clayton, Victori...
Validation of eGFR for Detecting Associations Between Serum Protein Biomarkers and Subsequent GFR Decline
Validation of eGFR for Detecting Associations Between Serum Protein Biomarkers and Subsequent GFR Decline
Background Several serum protein biomarkers have been proposed as risk factors for GFR decline us
In Memoriam: Prof. Floyd C. Rector, Jr.1929–2023
In Memoriam: Prof. Floyd C. Rector, Jr.1929–2023
In Memoriam: Prof. Floyd C. Rector, Jr.1929–2023 : Journal of the American Society of Nephrology ...
Outpatient Antibiotic Use is Not Associated with an Increased Risk of First-Time Symptomatic Kidney Stones
Outpatient Antibiotic Use is Not Associated with an Increased Risk of First-Time Symptomatic Kidney Stones
Background: Antibiotics modify gastrointestinal and urinary microbiomes, which may contribute to
Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe
Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe
1Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado ...
Dialysis on the Mind: The Evolution of Hemodialysis-Related Acute Brain Injury
Dialysis on the Mind: The Evolution of Hemodialysis-Related Acute Brain Injury
1Department of Intensive Care Medicine, Mater Misericordiae University Hospital, Dublin, Ireland 2Global Brai...
Inhibition of Importin-α-mediated Nuclear Localization of Dendrin Attenuates Podocyte Loss and Glomerulosclerosis
Inhibition of Importin-α-mediated Nuclear Localization of Dendrin Attenuates Podocyte Loss and Glomerulosclerosis
Background: Nuclear translocation of dendrin is observed in the glomeruli in numerous human renal
Target Trial Emulation to Improve Causal Inference from Observational Data: What, Why, and How?
Target Trial Emulation to Improve Causal Inference from Observational Data: What, Why, and How?
Target trial emulation has drastically improved the quality of observational studies investigating t
Detecting Neonatal AKI by Serum Cystatin C
Detecting Neonatal AKI by Serum Cystatin C
Background Serum creatinine is not a sensitive biomarker for AKI in neonates. A better biomarker-
Molecular MR Imaging of Renal Fibrogenesis in Mice
Molecular MR Imaging of Renal Fibrogenesis in Mice
Background: In most chronic kidney diseases, lysyl oxidase oxidation of collagen forms allysine s
Validation of Estimated GFR for Detecting Associations Between Serum Protein Biomarkers and Subsequent GFR Decline
Validation of Estimated GFR for Detecting Associations Between Serum Protein Biomarkers and Subsequent GFR Decline
Background: Several serum protein biomarkers have been proposed as risk factors for GFR decline u
Urine Metabolomic Versus Standard Chemistry Analysis: What Can Metabolomic Analysis Bring to the Treatment and Prevention of Urolithiasis?
Urine Metabolomic Versus Standard Chemistry Analysis: What Can Metabolomic Analysis Bring to the Treatment and Prevention of Urolithiasis?
We read with great interest the recent publication entitled “Nuclear Magnetic Resonance (NMR) Metabolomic Profiling and Ur...
mTORC2, a Novel “Twist” on the Epithelial Sodium Channel (ENaC)
mTORC2, a Novel “Twist” on the Epithelial Sodium Channel (ENaC)
1Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, O...
Tuberous sclerosis complex kidney lesion pathogenesis: a developmental perspective
Tuberous sclerosis complex kidney lesion pathogenesis: a developmental perspective
The phenotypic diversity of tuberous sclerosis complex (TSC) kidney pathology is enigmatic. Despite
Cardioprotective Effect of Acute Intradialytic Exercise: A Comprehensive Speckle-Tracking Echocardiography Analysis
Cardioprotective Effect of Acute Intradialytic Exercise: A Comprehensive Speckle-Tracking Echocardiography Analysis
Background Hemodialysis induces left ventricular transient myocardial dysfunction. A complex inte
Representation of Racial and Ethnic Minorities in Nephrology Clinical Trials: A Systematic Review and Meta-Analysis
Representation of Racial and Ethnic Minorities in Nephrology Clinical Trials: A Systematic Review and Meta-Analysis
Background Background Underrepresentation of racial and ethnic minorities in clinical trials cou
Economic Impact of a Change in Medicaid Coverage Policy for Dialysis Care of Undocumented Immigrants
Economic Impact of a Change in Medicaid Coverage Policy for Dialysis Care of Undocumented Immigrants
1Department of Medicine, University of Colorado, Aurora, Colorado 2Department of Renal Diseases and Hypertens...
Thrombopoietin-dependent Myelo-megakaryopoiesis Fuels Thromboinflammation and Worsens Antibody-mediated Chronic Renal Microvascular Injury
Thrombopoietin-dependent Myelo-megakaryopoiesis Fuels Thromboinflammation and Worsens Antibody-mediated Chronic Renal Microvascular Injury
Background: Chronic thromboinflammation provokes microvascular alterations and rarefaction, promo
Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy
Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy
Background Endocytosis, recycling, and degradation of proteins are essential functions of mammali
Association of Primary versus Rotating Nephrologist Model of Care in Hemodialysis Programs with Patient Outcomes
Association of Primary versus Rotating Nephrologist Model of Care in Hemodialysis Programs with Patient Outcomes
1Division of Nephrology, St. Michael’s Hospital, Toronto, Canada 2Li Ka Shing Knowledge Institute, St. Michae...
Unbiased Human Kidney Tissue Proteomics Identifies Matrix Metalloproteinase 7 as a Kidney Disease Biomarker
Unbiased Human Kidney Tissue Proteomics Identifies Matrix Metalloproteinase 7 as a Kidney Disease Biomarker
Background Diabetic kidney disease is responsible for close to half of all chronic and end-stage
Carbamylation in Uremia
Carbamylation in Uremia
Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Corresponden...
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