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Toxics, Vol. 10, Pages 753: Toxicological Comparison of Pesticide Active Substances Approved for Conventional vs. Organic Agriculture in Europe
Toxics, Vol. 10, Pages 753: Toxicological Comparison of Pesticide Active Substances Approved for Conventional vs. Organic Agriculture in Europe
There is much debate about whether the (mostly synthetic) pesticide active substances (AS) in conventional agriculture hav...
Toxics, Vol. 10, Pages 760: Advancing New Approach Methodologies (NAMs) for Tobacco Harm Reduction: Synopsis from the 2021 CORESTA SSPT—NAMs Symposium
Toxics, Vol. 10, Pages 760: Advancing New Approach Methodologies (NAMs) for Tobacco Harm Reduction: Synopsis from the 2021 CORESTA SSPT—NAMs Symposium
New approach methodologies (NAMs) are emerging chemical safety assessment tools consisting of in vitro and in silico (comp...
Toxics, Vol. 10, Pages 762: Microplastics in Widely Used Polypropylene-Made Food Containers
Toxics, Vol. 10, Pages 762: Microplastics in Widely Used Polypropylene-Made Food Containers
As a potential threat to human health, ingestion of microplastics (MPs) has become of concern. Limited studies have carefu...
Toxics, Vol. 10, Pages 761: Optimization of Cancer Risk Assessment Models for PM2.5-Bound PAHs: Application in Jingzhong, Shanxi, China
Toxics, Vol. 10, Pages 761: Optimization of Cancer Risk Assessment Models for PM2.5-Bound PAHs: Application in Jingzhong, Shanxi, China
The accurate evaluation of the carcinogenic risk of PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) is crucial because...
Natural phytochemicals prevent side effects in BRCA-mutated ovarian cancer and PARP inhibitor treatment
Natural phytochemicals prevent side effects in BRCA-mutated ovarian cancer and PARP inhibitor treatment
Ovarian cancer is among the most common malignant tumors in gynecology and is characterized by insidious onset, poor diffe...
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting
Cancer cachexia is a multifactorial syndrome defined by progressive loss of body weight with specific depletion of skeleta...
Effect of aspirin in patients with established asymptomatic carotid atherosclerosis: A systematic review and meta-analysis
Effect of aspirin in patients with established asymptomatic carotid atherosclerosis: A systematic review and meta-analysis
Background: Aspirin is widely used as an antiplatelet agent for secondary prevention in patients with atherosclerotic card...
3CLpro inhibitors: DEL-based molecular generation
3CLpro inhibitors: DEL-based molecular generation
Molecular generation (MG) via machine learning (ML) has speeded drug structural optimization, especially for targets with ...
Is the vesicular nucleotide transporter a molecular target of eicosapentaenoic acid?
Is the vesicular nucleotide transporter a molecular target of eicosapentaenoic acid?
Vesicular nucleotide transporter (VNUT), an active transporter for nucleotides in secretory vesicles, is responsible for t...
Development and validation of a new non-disease-specific survey tool to assess self-reported adherence to medication
Development and validation of a new non-disease-specific survey tool to assess self-reported adherence to medication
Background: Patients’ non-adherence to medication affects both patients themselves and healthcare systems. Consequences in...
Anticancer activity of glycoalkaloids from Solanum plants: A review
Anticancer activity of glycoalkaloids from Solanum plants: A review
Cancer is still one of the main causes of death worldwide. For this reason, new compounds that have chemotherapeutic poten...
Aberrant Immunoglobulin G Glycosylation in Multiple Sclerosis
Aberrant Immunoglobulin G Glycosylation in Multiple Sclerosis
A hallmark of the inflammatory response in multiple sclerosis (MS) is the presence of intrathecal Immunoglobulin G (IgG) a...
miR-146a Dysregulates Energy Metabolism During Neuroinflammation
miR-146a Dysregulates Energy Metabolism During Neuroinflammation
Alzheimer’s disease (AD) and other neurodegenerative diseases are characterized by chronic neuroinflammation and a r...
Chronic Opioid Administration is Associated with Prevotella-dominated Dysbiosis in SIVmac251 Infected, cART-treated Macaques
Chronic Opioid Administration is Associated with Prevotella-dominated Dysbiosis in SIVmac251 Infected, cART-treated Macaques
People living with the human immunodeficiency virus (HIV) have an elevated risk of opioid misuse due to both prescriptions...
Synergistic Effect and Mechanism of Apoptosis Induction by Morphine and the HIV-1gp120V3 Loop in Hippocampal Neurons
Synergistic Effect and Mechanism of Apoptosis Induction by Morphine and the HIV-1gp120V3 Loop in Hippocampal Neurons
HIV-associated neurocognitive disorders (HAND) are a collective name for neurological disorders associated with HIV-1 infe...
Agathisflavone Modifies Microglial Activation State and Myelination in Organotypic Cerebellar Slices Culture
Agathisflavone Modifies Microglial Activation State and Myelination in Organotypic Cerebellar Slices Culture
Oligodendrocytes produce the myelin that is critical for rapid neuronal transmission in the central nervous system (CNS). ...
A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway
Available online 5 December 2022Author links open overlay panelAbstractInterleukin-1 receptor-associated kinase 4 (IRAK4) ...
Toxics, Vol. 10, Pages 757: Indoor Particle’s Pollution in Bucharest, Romania
Toxics, Vol. 10, Pages 757: Indoor Particle’s Pollution in Bucharest, Romania
Air pollution risk factor on human health was surpassed only by high blood pressure, tobacco use and poor diet. Total numb...