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The Immunology of Psoriasis—Current Concepts in Pathogenesis
The Immunology of Psoriasis—Current Concepts in Pathogenesis
Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-remitting course. The last decade...
Prenatal Exposure to Air Pollutants Associated with Allergic Diseases in Children: Which Pollutant, When Exposure, and What Disease? A Systematic Review and Meta-analysis
Prenatal Exposure to Air Pollutants Associated with Allergic Diseases in Children: Which Pollutant, When Exposure, and What Disease? A Systematic Review and Meta-analysis
This systematic review aims to identify the association between prenatal exposure to air pollutants and allergic diseases ...
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis is a major clinical problem in many autoimmune diseases, including primary biliary cholangitis (PBC), the mos...
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
Peanut allergy is a leading cause of severe food reactions. This meta-analysis evaluates the efficacy and safety of epicut...
Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Effective treatment of drug reactions with eosinophilia and systemic symptoms (DReSS) requires early diagnosis and close m...
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
In the field of contemporary medicine, autoimmune diseases (AIDs) are a prevalent and debilitating group of illnesses. How...
Tissue-Resident Memory T Cells in Allergy
Tissue-Resident Memory T Cells in Allergy
Tissue-resident memory T (TRM) cells constitute a distinct subset within the memory T cell population, serving as the vang...
Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies
Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies
Asthma and allergies are some of the most common chronic disorders affecting children, the prevalence of which has been in...
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the ...
A Global View of Pemphigus: Geographical Variations
A Global View of Pemphigus: Geographical Variations
Pemphigus, an autoimmune intraepidermal bullous disease group with roughly eight distinct forms, includes pemphigus vulgar...
Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization
Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization
Mast cells (MCs) are commonly recognized for their crucial involvement in the pathogenesis of allergic diseases, but over ...
A Comprehensive Review of Sulfonamide Hypersensitivity: Implications for Clinical Practice
A Comprehensive Review of Sulfonamide Hypersensitivity: Implications for Clinical Practice
Sulfonamides, which are drugs commonly prescribed in hospital and outpatient settings, have historically been associated w...
Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications
Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications
Chronic rhinosinusitis (CRS) is a highly heterogeneous disease characterized by inflammation in the nasal and sinus mucosa...
Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis
Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an increased risk of cardiovascular events, d...
Autoinflammatory Keratinization Diseases—The Concept, Pathophysiology, and Clinical Implications
Autoinflammatory Keratinization Diseases—The Concept, Pathophysiology, and Clinical Implications
Recent advances in medical genetics elucidated the background of diseases characterized by superficial dermal and epiderma...
Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches
Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches
Bullous pemphigoid is one of the most common autoimmune bullous diseases occurring primarily in the elderly. Pathogenic au...
A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency—Real-World Data
A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency—Real-World Data
Hereditary angioedema (HAE) and acquired C1-inhibitor deficiency (AAE-C1-INH) are orphan diseases. Berotralstat is a recen...
Eosinophil-Associated Gastrointestinal Manifestations During OIT
Eosinophil-Associated Gastrointestinal Manifestations During OIT
Gastrointestinal adverse events are common during oral immunotherapy (OIT) for food allergy and range from immediate IgE-m...
Vernal Keratoconjunctivitis: A Systematic Review
Vernal Keratoconjunctivitis: A Systematic Review
Vernal keratoconjunctivitis (VKC) is a chronic, bilateral corneal and conjunctival problem which typically presents in you...
Treatable Traits in Systemic Sclerosis
Treatable Traits in Systemic Sclerosis
Systemic sclerosis (SSc) is a chronic systemic disease within the spectrum of connective tissue diseases, specifically cha...
Hypersensitivity Reactions to Taxanes: A Comprehensive and Systematic Review of the Efficacy and Safety of Desensitization
Hypersensitivity Reactions to Taxanes: A Comprehensive and Systematic Review of the Efficacy and Safety of Desensitization
Taxanes in the treatment of cancer are associated with a significant incidence of hypersensitivity reactions, which may pr...
Shared Pathogenicity Features and Sequences between EBV, SARS-CoV-2, and HLA Class I Molecule-binding Motifs with a Potential Role in Autoimmunity
Shared Pathogenicity Features and Sequences between EBV, SARS-CoV-2, and HLA Class I Molecule-binding Motifs with a Potential Role in Autoimmunity
Epstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are extraordinary in their abili...
Environmental Risk Factors, Protective Factors, and Biomarkers for Allergic Rhinitis: A Systematic Umbrella Review of the Evidence
Environmental Risk Factors, Protective Factors, and Biomarkers for Allergic Rhinitis: A Systematic Umbrella Review of the Evidence
Many potential environmental risk factors, protective factors, and biomarkers of AR have been published, but so far, the s...
During Sepsis and COVID-19, the Pro-Inflammatory and Anti-Inflammatory Responses Are Concomitant
During Sepsis and COVID-19, the Pro-Inflammatory and Anti-Inflammatory Responses Are Concomitant
The most severe forms of COVID-19 share many features with bacterial sepsis and have thus been considered to be a viral se...
γδ T Cells and Allergic Diseases
γδ T Cells and Allergic Diseases
Gamma–delta (γδ) T cells play an essential role in allergic diseases and have emerged as a potential treat...
COVID-19, Coronavirus Vaccines, and Possible Association with Lipschütz Vulvar Ulcer: A Systematic Review
COVID-19, Coronavirus Vaccines, and Possible Association with Lipschütz Vulvar Ulcer: A Systematic Review
Lipschütz genital ulcer is a self-limited, non-sexually acquired disorder characterized by the sudden onset of a few ...
Perspectives on Mycophenolate Mofetil in the Management of Autoimmunity
Perspectives on Mycophenolate Mofetil in the Management of Autoimmunity
Before becoming a cornerstone in the treatment of numerous immune-mediated diseases, mycophenolate mofetil (MMF) was first...
Food Allergy Labeling Laws: International Guidelines for Residents and Travelers
Food Allergy Labeling Laws: International Guidelines for Residents and Travelers
The prevalence of food allergies varies by country, as does each country’s food allergen labeling. While labeling la...
Single-Cell Analysis of Patients with Axial Spondyloarthritis After Anti-TNFα Treatment: Experimental Data and Review of the Literature
Single-Cell Analysis of Patients with Axial Spondyloarthritis After Anti-TNFα Treatment: Experimental Data and Review of the Literature
Axial spondyloarthritis (Ax-SpA) is a chronic inflammatory disease that predominantly affects the axial joints and is most...
Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review
Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review
Air pollution is associated with multiple health problems worldwide, contributing to increased morbidity and mortality. At...
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