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Immunological Effects of Electronic Cigarette Use: A Review of Current Evidence
Immunological Effects of Electronic Cigarette Use: A Review of Current Evidence
Electronic cigarettes (EC) have emerged as a popular alternative to traditional tobacco products, but their impact on immu...
Short-Chain Fatty Acids: Promising Therapeutic Targets for Respiratory Syncytial Virus Infection
Short-Chain Fatty Acids: Promising Therapeutic Targets for Respiratory Syncytial Virus Infection
The intestinal microbiota is a complex community of organisms present in the human gastrointestinal tract, some of which c...
TTC7A Variants Results in Gastrointestinal Defects and Immunodeficiency Syndrome: Case Series and Literature Review
TTC7A Variants Results in Gastrointestinal Defects and Immunodeficiency Syndrome: Case Series and Literature Review
Gastrointestinal Defects and Immunodeficiency Syndrome-1 (GIDID-1), caused by abnormalities in TTC7A, is an autosomal rece...
Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective
Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective
In recent years, epigenetic modifications have attracted significant attention due to their unique regulatory mechanisms a...
Exosomes in Autoimmune Diseases: A Review of Mechanisms and Diagnostic Applications
Exosomes in Autoimmune Diseases: A Review of Mechanisms and Diagnostic Applications
Exosomes, small extracellular vesicles secreted by various cell types, have emerged as key players in the pathophysiology ...
Copy Number Variation in Asthma: An Integrative Review
Copy Number Variation in Asthma: An Integrative Review
Asthma is a complex disease with varied clinical manifestations resulting from the interaction between environmental and g...
Olfactory Dysfunction in Allergic Rhinitis
Olfactory Dysfunction in Allergic Rhinitis
Olfactory dysfunction (OD) can have serious consequences as it hinders individuals from detecting important warning signal...
Group 3 Innate Lymphoid Cells: A Potential Therapeutic Target for Steroid Resistant Asthma
Group 3 Innate Lymphoid Cells: A Potential Therapeutic Target for Steroid Resistant Asthma
Asthma is a chronic airway inflammatory disease that affects millions globally. Although glucocorticoids are a mainstay of...
Regulatory Roles of SWI/SNF Chromatin Remodeling Complexes in Immune Response and Inflammatory Diseases
Regulatory Roles of SWI/SNF Chromatin Remodeling Complexes in Immune Response and Inflammatory Diseases
The switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complexes (also referred to as BAF complexes) are compos...
Advancements in the Study of the Immune Molecule NKp46 in Immune System-related Diseases
Advancements in the Study of the Immune Molecule NKp46 in Immune System-related Diseases
NKp46 is a natural killer cell activating receptor primarily expressed on NK cells and non-NK innate lymphoid cells. In th...
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review
Long-term prophylaxis (LTP) has been shown to reduce the frequency of hereditary angioedema (HAE) attacks; however, attack...
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
Apart from the skin and mucosal immune barrier, the first line of defense of the human immune system includes MDA5 (ifih1 ...
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases
Regulatory T (Treg) cells are crucial for maintaining immune tolerance by suppressing response to self-antigens and harmle...
Non-allergic Hypersensitivity Reactions to Immunoglobulin Preparations in Antibody Deficiencies: What Role for Anti-IgA IgG and Complement Activation?
Non-allergic Hypersensitivity Reactions to Immunoglobulin Preparations in Antibody Deficiencies: What Role for Anti-IgA IgG and Complement Activation?
The presence of IgG anti-IgA in the serum of primary immunodeficiency (PID) patients has long been considered responsible ...
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis
Non-allergic rhinitis (NAR) is a prevalent condition with limited effective treatments. Capsaicin, an agonist of the trans...
Neutrophils in Atopic Dermatitis
Neutrophils in Atopic Dermatitis
Neutrophils have a critical role in inflammation. Recent studies have identified their distinctive presence in certain typ...
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy
Allergen-based diagnostics are essential in the management algorithm of allergic diseases. Unlike systemic allergy, where ...
Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases
Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases
The role of abnormal epigenetic modifications, particularly DNA methylation, in the pathogenesis of autoimmune rheumatic d...
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases
Autoimmune diseases (AIDs) are complex in etiology and diverse in classification but clinically show similar symptoms such...
Fungal Head and Neck Dermatitis: Current Understanding and Management
Fungal Head and Neck Dermatitis: Current Understanding and Management
Head and neck dermatitis (HND) is a form of atopic dermatitis (AD) that affects the seborrheic areas of the body and cause...
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly m...
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory...
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical featur...
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblasts are crucial components of the skin structure. They were traditionally believed to maintain the skin’s st...
Down Syndrome and Autoimmune Disease
Down Syndrome and Autoimmune Disease
Down syndrome is the most common genetic cause of intellectual disability and has previously been associated with a variet...
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Tropomyosin has been identified as the major cross-reactive shellfish allergen, but recent studies showed the presence of ...
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since c...
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
Secondary prevention with penicillin aims to prevent further episodes of acute rheumatic fever and subsequent development ...
Uncovering the Cellular Microenvironment in Chronic Rhinosinusitis via Single-Cell RNA Sequencing: Application and Future Directions
Uncovering the Cellular Microenvironment in Chronic Rhinosinusitis via Single-Cell RNA Sequencing: Application and Future Directions
Chronic rhinosinusitis (CRS) is a heterogenic disease characterized by persistent mucosal inflammation of the upper airway...
Survival After Hematopoietic Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID): A Worldwide Review of the Prognostic Variables
Survival After Hematopoietic Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID): A Worldwide Review of the Prognostic Variables
This study aims to perform an extensive review of the literature that evaluates various factors that affect the survival r...
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