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Fungal Head and Neck Dermatitis: Current Understanding and Management
Fungal Head and Neck Dermatitis: Current Understanding and Management
Head and neck dermatitis (HND) is a form of atopic dermatitis (AD) that affects the seborrheic areas of the body and cause...
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly m...
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory...
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical featur...
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblasts are crucial components of the skin structure. They were traditionally believed to maintain the skin’s st...
Down Syndrome and Autoimmune Disease
Down Syndrome and Autoimmune Disease
Down syndrome is the most common genetic cause of intellectual disability and has previously been associated with a variet...
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Tropomyosin has been identified as the major cross-reactive shellfish allergen, but recent studies showed the presence of ...
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since c...
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
Secondary prevention with penicillin aims to prevent further episodes of acute rheumatic fever and subsequent development ...
Uncovering the Cellular Microenvironment in Chronic Rhinosinusitis via Single-Cell RNA Sequencing: Application and Future Directions
Uncovering the Cellular Microenvironment in Chronic Rhinosinusitis via Single-Cell RNA Sequencing: Application and Future Directions
Chronic rhinosinusitis (CRS) is a heterogenic disease characterized by persistent mucosal inflammation of the upper airway...
Survival After Hematopoietic Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID): A Worldwide Review of the Prognostic Variables
Survival After Hematopoietic Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID): A Worldwide Review of the Prognostic Variables
This study aims to perform an extensive review of the literature that evaluates various factors that affect the survival r...
The Immunology of Psoriasis—Current Concepts in Pathogenesis
The Immunology of Psoriasis—Current Concepts in Pathogenesis
Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-remitting course. The last decade...
Prenatal Exposure to Air Pollutants Associated with Allergic Diseases in Children: Which Pollutant, When Exposure, and What Disease? A Systematic Review and Meta-analysis
Prenatal Exposure to Air Pollutants Associated with Allergic Diseases in Children: Which Pollutant, When Exposure, and What Disease? A Systematic Review and Meta-analysis
This systematic review aims to identify the association between prenatal exposure to air pollutants and allergic diseases ...
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis is a major clinical problem in many autoimmune diseases, including primary biliary cholangitis (PBC), the mos...
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
Peanut allergy is a leading cause of severe food reactions. This meta-analysis evaluates the efficacy and safety of epicut...
Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Effective treatment of drug reactions with eosinophilia and systemic symptoms (DReSS) requires early diagnosis and close m...
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
In the field of contemporary medicine, autoimmune diseases (AIDs) are a prevalent and debilitating group of illnesses. How...
Tissue-Resident Memory T Cells in Allergy
Tissue-Resident Memory T Cells in Allergy
Tissue-resident memory T (TRM) cells constitute a distinct subset within the memory T cell population, serving as the vang...
Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies
Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies
Asthma and allergies are some of the most common chronic disorders affecting children, the prevalence of which has been in...
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the ...
A Global View of Pemphigus: Geographical Variations
A Global View of Pemphigus: Geographical Variations
Pemphigus, an autoimmune intraepidermal bullous disease group with roughly eight distinct forms, includes pemphigus vulgar...
Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization
Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization
Mast cells (MCs) are commonly recognized for their crucial involvement in the pathogenesis of allergic diseases, but over ...
A Comprehensive Review of Sulfonamide Hypersensitivity: Implications for Clinical Practice
A Comprehensive Review of Sulfonamide Hypersensitivity: Implications for Clinical Practice
Sulfonamides, which are drugs commonly prescribed in hospital and outpatient settings, have historically been associated w...
Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications
Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications
Chronic rhinosinusitis (CRS) is a highly heterogeneous disease characterized by inflammation in the nasal and sinus mucosa...
Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis
Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an increased risk of cardiovascular events, d...
Autoinflammatory Keratinization Diseases—The Concept, Pathophysiology, and Clinical Implications
Autoinflammatory Keratinization Diseases—The Concept, Pathophysiology, and Clinical Implications
Recent advances in medical genetics elucidated the background of diseases characterized by superficial dermal and epiderma...
Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches
Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches
Bullous pemphigoid is one of the most common autoimmune bullous diseases occurring primarily in the elderly. Pathogenic au...
A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency—Real-World Data
A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency—Real-World Data
Hereditary angioedema (HAE) and acquired C1-inhibitor deficiency (AAE-C1-INH) are orphan diseases. Berotralstat is a recen...
Eosinophil-Associated Gastrointestinal Manifestations During OIT
Eosinophil-Associated Gastrointestinal Manifestations During OIT
Gastrointestinal adverse events are common during oral immunotherapy (OIT) for food allergy and range from immediate IgE-m...
Vernal Keratoconjunctivitis: A Systematic Review
Vernal Keratoconjunctivitis: A Systematic Review
Vernal keratoconjunctivitis (VKC) is a chronic, bilateral corneal and conjunctival problem which typically presents in you...
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