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Advancements in the Study of the Immune Molecule NKp46 in Immune System-related Diseases
Advancements in the Study of the Immune Molecule NKp46 in Immune System-related Diseases
NKp46 is a natural killer cell activating receptor primarily expressed on NK cells and non-NK innate lymphoid cells. In th...
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review
Long-term prophylaxis (LTP) has been shown to reduce the frequency of hereditary angioedema (HAE) attacks; however, attack...
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
Apart from the skin and mucosal immune barrier, the first line of defense of the human immune system includes MDA5 (ifih1 ...
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases
Regulatory T (Treg) cells are crucial for maintaining immune tolerance by suppressing response to self-antigens and harmle...
Non-allergic Hypersensitivity Reactions to Immunoglobulin Preparations in Antibody Deficiencies: What Role for Anti-IgA IgG and Complement Activation?
Non-allergic Hypersensitivity Reactions to Immunoglobulin Preparations in Antibody Deficiencies: What Role for Anti-IgA IgG and Complement Activation?
The presence of IgG anti-IgA in the serum of primary immunodeficiency (PID) patients has long been considered responsible ...
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis
Non-allergic rhinitis (NAR) is a prevalent condition with limited effective treatments. Capsaicin, an agonist of the trans...
Neutrophils in Atopic Dermatitis
Neutrophils in Atopic Dermatitis
Neutrophils have a critical role in inflammation. Recent studies have identified their distinctive presence in certain typ...
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy
Allergen-based diagnostics are essential in the management algorithm of allergic diseases. Unlike systemic allergy, where ...
Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases
Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases
The role of abnormal epigenetic modifications, particularly DNA methylation, in the pathogenesis of autoimmune rheumatic d...
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases
Autoimmune diseases (AIDs) are complex in etiology and diverse in classification but clinically show similar symptoms such...
Fungal Head and Neck Dermatitis: Current Understanding and Management
Fungal Head and Neck Dermatitis: Current Understanding and Management
Head and neck dermatitis (HND) is a form of atopic dermatitis (AD) that affects the seborrheic areas of the body and cause...
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly m...
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory...
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical featur...
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblasts are crucial components of the skin structure. They were traditionally believed to maintain the skin’s st...
Down Syndrome and Autoimmune Disease
Down Syndrome and Autoimmune Disease
Down syndrome is the most common genetic cause of intellectual disability and has previously been associated with a variet...
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Tropomyosin has been identified as the major cross-reactive shellfish allergen, but recent studies showed the presence of ...
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since c...
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
Secondary prevention with penicillin aims to prevent further episodes of acute rheumatic fever and subsequent development ...
Uncovering the Cellular Microenvironment in Chronic Rhinosinusitis via Single-Cell RNA Sequencing: Application and Future Directions
Uncovering the Cellular Microenvironment in Chronic Rhinosinusitis via Single-Cell RNA Sequencing: Application and Future Directions
Chronic rhinosinusitis (CRS) is a heterogenic disease characterized by persistent mucosal inflammation of the upper airway...
Survival After Hematopoietic Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID): A Worldwide Review of the Prognostic Variables
Survival After Hematopoietic Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID): A Worldwide Review of the Prognostic Variables
This study aims to perform an extensive review of the literature that evaluates various factors that affect the survival r...
The Immunology of Psoriasis—Current Concepts in Pathogenesis
The Immunology of Psoriasis—Current Concepts in Pathogenesis
Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-remitting course. The last decade...
Prenatal Exposure to Air Pollutants Associated with Allergic Diseases in Children: Which Pollutant, When Exposure, and What Disease? A Systematic Review and Meta-analysis
Prenatal Exposure to Air Pollutants Associated with Allergic Diseases in Children: Which Pollutant, When Exposure, and What Disease? A Systematic Review and Meta-analysis
This systematic review aims to identify the association between prenatal exposure to air pollutants and allergic diseases ...
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis is a major clinical problem in many autoimmune diseases, including primary biliary cholangitis (PBC), the mos...
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
Peanut allergy is a leading cause of severe food reactions. This meta-analysis evaluates the efficacy and safety of epicut...
Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Effective treatment of drug reactions with eosinophilia and systemic symptoms (DReSS) requires early diagnosis and close m...
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
In the field of contemporary medicine, autoimmune diseases (AIDs) are a prevalent and debilitating group of illnesses. How...
Tissue-Resident Memory T Cells in Allergy
Tissue-Resident Memory T Cells in Allergy
Tissue-resident memory T (TRM) cells constitute a distinct subset within the memory T cell population, serving as the vang...
Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies
Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies
Asthma and allergies are some of the most common chronic disorders affecting children, the prevalence of which has been in...
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the ...
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