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Single-Cell Analysis of Patients with Axial Spondyloarthritis After Anti-TNFα Treatment: Experimental Data and Review of the Literature
Single-Cell Analysis of Patients with Axial Spondyloarthritis After Anti-TNFα Treatment: Experimental Data and Review of the Literature
Axial spondyloarthritis (Ax-SpA) is a chronic inflammatory disease that predominantly affects the axial joints and is most...
Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review
Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review
Air pollution is associated with multiple health problems worldwide, contributing to increased morbidity and mortality. At...
The Evolving Landscape of Fecal Microbial Transplantation
The Evolving Landscape of Fecal Microbial Transplantation
The human gastrointestinal tract houses an enormous microbial ecosystem. Recent studies have shown that the gut microbiota...
A Review of Persistent Post-COVID Syndrome (PPCS)
A Review of Persistent Post-COVID Syndrome (PPCS)
Persistent post-COVID syndrome, also referred to as long COVID, is a pathologic entity, which involves persistent physical...
Epigenetic Dysregulation in Autoimmune and Inflammatory Skin Diseases
Epigenetic Dysregulation in Autoimmune and Inflammatory Skin Diseases
Epigenetics is the study of heritable, reversible gene expression patterns that do not originate from alterations in the D...
New Mechanistic Advances in FcεRI-Mast Cell–Mediated Allergic Signaling
New Mechanistic Advances in FcεRI-Mast Cell–Mediated Allergic Signaling
Mast cells originate from the CD34+/CD117+ hematopoietic progenitors in the bone marrow, migrate into circulation, and ult...
Systemic Sclerosis Association with Malignancy
Systemic Sclerosis Association with Malignancy
The association of systemic sclerosis (SSc) and cancer is well known from several decades suggesting common genetic and en...
Hair Follicle Melanocytes Initiate Autoimmunity in Alopecia Areata: a Trigger Point
Hair Follicle Melanocytes Initiate Autoimmunity in Alopecia Areata: a Trigger Point
Alopecia areata (AA) is characterized by common non-scarring alopecia due to autoimmune disorders. To date, the specific p...
The Genetics of Eczema Herpeticum
The Genetics of Eczema Herpeticum
Eczema herpeticum (EH) is a viral skin infection caused by herpes simplex virus (HSV) superimposed on eczematous skin lesi...
Pathophysiology, Diagnosis, and Management of Chronic Spontaneous Urticaria: A Literature Review
Pathophysiology, Diagnosis, and Management of Chronic Spontaneous Urticaria: A Literature Review
Chronic spontaneous urticaria (CSU) is characterized by recurring wheals that last 6 weeks or longer without an i...
The Treatment of Primary Immune Deficiencies: Lessons Learned and Future Opportunities
The Treatment of Primary Immune Deficiencies: Lessons Learned and Future Opportunities
Primary immunodeficiency is a group of disorders associated with susceptibility to infectious agents and the development o...
A Summary on the Genetics of Systemic Lupus Erythematosus, Rheumatoid Arthritis, Systemic Sclerosis, and Sjögren’s Syndrome
A Summary on the Genetics of Systemic Lupus Erythematosus, Rheumatoid Arthritis, Systemic Sclerosis, and Sjögren’s Syndrome
Systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and Sjögren’s syndrome are four major a...
Inflammaging and Osteoarthritis
Inflammaging and Osteoarthritis
Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age worldwide. While in th...
Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers
Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers
Disease-specific autoantibodies are considered the most important biomarkers for systemic sclerosis (SSc), due to their ab...
T Cell Abnormalities in X-Linked Agammaglobulinaemia: an Updated Review
T Cell Abnormalities in X-Linked Agammaglobulinaemia: an Updated Review
X-linked agammaglobulinaemia (XLA) is a primary immunodeficiency (PID) resulting from a defect in the B cell development. ...
Correlates of Protection Against Respiratory Syncytial Virus Infection in Infancy
Correlates of Protection Against Respiratory Syncytial Virus Infection in Infancy
The highest morbidity and mortality from respiratory syncytial virus (RSV) infection occurs in young infants. Immunization...
Germinal Center-Related G Protein-Coupled Receptors in Antibody-Mediated Autoimmune Skin Diseases: from Basic Research to Clinical Trials
Germinal Center-Related G Protein-Coupled Receptors in Antibody-Mediated Autoimmune Skin Diseases: from Basic Research to Clinical Trials
Germinal center (GC) reaction greatly contributes to the humoral immune response, which begins in lymph nodes or other sec...
Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature
Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature
In autoimmune hepatitis (AIH), the persisting inflammation contributes to fibrosis progression, for which conventional bio...
Autoimmunity in Primary Immunodeficiencies (PID)
Autoimmunity in Primary Immunodeficiencies (PID)
Primary immunodeficiency (PID) may impact any component of the immune system. The number of PID and immune dysregulation d...
Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes
Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes
The hygiene hypothesis has been popularized as an explanation for the rapid increase in allergic disease observed over the...
Renal Disease and Systemic Sclerosis: an Update on Scleroderma Renal Crisis
Renal Disease and Systemic Sclerosis: an Update on Scleroderma Renal Crisis
Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc) with a mortality of 20% at 6...
Inflammaging and Frailty in Immune-Mediated Rheumatic Diseases: How to Address and Score the Issue
Inflammaging and Frailty in Immune-Mediated Rheumatic Diseases: How to Address and Score the Issue
Frailty is a new concept in rheumatology that can help identify people more likely to have less favorable outcomes. Sarcop...
Autoantibodies and Cancer Association: the Case of Systemic Sclerosis and Dermatomyositis
Autoantibodies and Cancer Association: the Case of Systemic Sclerosis and Dermatomyositis
Several rheumatic diseases have a perplexing association with cancer. Unraveling this mysterious connection is likely to p...
Infections or Vaccines Associated with Finkelstein-Seidlmayer Vasculitis: Systematic Review
Infections or Vaccines Associated with Finkelstein-Seidlmayer Vasculitis: Systematic Review
Finkelstein-Seidlmayer vasculitis, also referred to as acute hemorrhagic edema of young children, is a rare small-vessel l...
Allergy to Local Anesthetics is a Rarity: Review of Diagnostics and Strategies for Clinical Management
Allergy to Local Anesthetics is a Rarity: Review of Diagnostics and Strategies for Clinical Management
Local anesthetics (LA) are commonly used in procedures and in topical agents for pain management. With the increasing use ...
Real-Life Effectiveness of Benralizumab, Mepolizumab and Omalizumab in Severe Allergic Asthma Associated with Nasal Polyps
Real-Life Effectiveness of Benralizumab, Mepolizumab and Omalizumab in Severe Allergic Asthma Associated with Nasal Polyps
Biological therapies are available for the treatment of the severe allergic asthma (SAA) with blood eosinophil count ...
Correction to: Serum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single‑Center Experience and Literature Review
Correction to: Serum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single‑Center Experience and Literature Review
Correction to: Clinical Reviews in Allergy & Immunology
Clinical Treatment Options in Scleroderma: Recommendations and Comprehensive Review
Clinical Treatment Options in Scleroderma: Recommendations and Comprehensive Review
There are two major clinical subsets of scleroderma: (i) systemic sclerosis (SSc) is a complex systemic autoimmune disorde...
Systematic Review and Meta-analysis on the Association of Occupational Exposure to Free Crystalline Silica and Rheumatoid Arthritis
Systematic Review and Meta-analysis on the Association of Occupational Exposure to Free Crystalline Silica and Rheumatoid Arthritis
• Occupational exposure to free crystalline silica and tobacco smoking are associated with an increased risk rheumat...
Serum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single-Center Experience and Literature Review
Serum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single-Center Experience and Literature Review
Autoimmune hepatitis (AIH) is characterized by interface hepatitis, elevated serum alanine aminotransferase and aspartate ...
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