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Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss
Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss
The autonomic nervous system regulates pancreatic function. Islet capillaries are essential for the extension of axonal pr...
Ketone monoester ingestion increases postexercise serum erythropoietin concentrations in healthy men
Ketone monoester ingestion increases postexercise serum erythropoietin concentrations in healthy men
To our knowledge, this study was the first to assess the effects of ketone monoester ingestion on erythropoietin concentra...
Fibroblast Growth Factor 21 as a Potential Master Regulator in Metabolic Disorders
Fibroblast Growth Factor 21 as a Potential Master Regulator in Metabolic Disorders
Fibroblast growth factor 21 (FGF21) is an endocrine hormone that controls key metabolic processes and induces the synthesi...
High-resolution analysis of the cytosolic Ca2+ events in β cell collectives in situ
High-resolution analysis of the cytosolic Ca2+ events in β cell collectives in situ
Physiological glucose or ryanodine stimulation of β cell collectives generates a large number of [Ca2+]c events, which can...
Ketone monoester ingestion increases post-exercise serum erythropoietin concentrations in healthy men
Ketone monoester ingestion increases post-exercise serum erythropoietin concentrations in healthy men
Intravenous ketone body infusion can increase erythropoietin (EPO) concentrations, but responses to ketone monoester inges...
High resolution analysis of the cytosolic Ca2+ events in beta cell collectives in situ
High resolution analysis of the cytosolic Ca2+ events in beta cell collectives in situ
The release of peptide hormones is predominantly regulated by a transient increase in cytosolic Ca2+ concentration ([Ca2+]...
Inosine, Gut Microbiota, and Cancer Immunometabolism
Inosine, Gut Microbiota, and Cancer Immunometabolism
This article briefly reviews cancer immunity and the role of gut microbiota in carcinogenesis, followed by an understandin...
Obesity and Chronic Kidney Disease
Obesity and Chronic Kidney Disease
The prevalence of obesity has increased dramatically during the past decades, which has been a major health problem. Since...
Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1
Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1
Glucagon-secreting pancreatic α-cells play pivotal roles in the development of diabetes. Glucagon promotes insulin secreti...
Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity
Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity
Adipose tissue dysfunction is a key mechanism that leads to adiposity-based chronic disease. This study aimed to investiga...