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TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability
TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability
Metabolic reprogramming is a hallmark of various cancers. Targeting metabolic processes is a very attractive treatment for...
Long-term exposure to house dust mites accelerates lung cancer development in mice
Long-term exposure to house dust mites accelerates lung cancer development in mice
Individuals with certain chronic inflammatory lung diseases have a higher risk of developing lung cancer (LC). However, th...
Stroma-derived miR-214 coordinates tumor dissemination
Stroma-derived miR-214 coordinates tumor dissemination
Tumor progression is based on a close interaction between cancer cells and Tumor MicroEnvironment (TME). Here, we focus on...
Repurposing nitric oxide donating drugs in cancer therapy through immune modulation
Repurposing nitric oxide donating drugs in cancer therapy through immune modulation
Nitric oxide-releasing drugs are used for cardiovascular diseases; however, their effects on the tumor immune microenviron...
LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer
LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer
Metastasis and drug resistance of breast cancer have become a barrier to treating patients successfully. Long noncoding RN...
Dose fractionation of CAR-T cells. A systematic review of clinical outcomes
Dose fractionation of CAR-T cells. A systematic review of clinical outcomes
CAR-T cells are widely recognized for their potential to successfully treat hematologic cancers and provide durable respon...
Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis
Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis
Sorafenib resistance is a key impediment to successful treatment of patients with advanced hepatocellular carcinoma (HCC) ...