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Revisiting the role of glucagon in health, diabetes mellitus and other metabolic diseases
Revisiting the role of glucagon in health, diabetes mellitus and other metabolic diseases
Insulin and glucagon exert opposing effects on glucose metabolism and, consequently, pancreatic islet β-cells and ...
Interventions in people newly diagnosed with type 1 diabetes mellitus
Interventions in people newly diagnosed with type 1 diabetes mellitus
Type 1 diabetes mellitus (T1DM) is characterized by a gradual loss of functional β-cells, leading to reliance on insulin a...
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization
Findings from the largest longitudinal study (315 participants) on psychosocial functioning in transgender or nonbinary yo...
A perspective on treating type 1 diabetes mellitus before insulin is needed
A perspective on treating type 1 diabetes mellitus before insulin is needed
Type 1 diabetes mellitus (T1DM) is a progressive autoimmune disease that starts long before a clinical diagnosis is made. ...
The metabolic benefits of exercise-induced hepatic autophagy
The metabolic benefits of exercise-induced hepatic autophagy
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
A novel resource to study endometriosis at the single-cell level
A novel resource to study endometriosis at the single-cell level
A transcriptomic analysis of endometriosis and comparison tissues has been conducted, revealing a rich and complex catalog...
GLP1: the early steps of a success story
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On the cutting edge: perspectives in bioenergetics
The field of bioenergetics is rapidly expanding with new discoveries of mechanisms and potential therapeutic targets. The ...
Reprogramming lymph nodes in type 1 diabetes mellitus
Reprogramming lymph nodes in type 1 diabetes mellitus
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Sulfonylurea secondary failure mechanism identified
Sulfonylurea secondary failure mechanism identified
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
Consensus Statement on the definition and classification of metabolic hyperferritinaemia
Consensus Statement on the definition and classification of metabolic hyperferritinaemia
Hyperferritinaemia is a common laboratory finding that is often associated with metabolic dysfunction and fatty liver. Met...
The effect of long-term statin use on diabetic nephropathy
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Aster pathway maintains hepatic cholesterol homeostasis
Aster pathway maintains hepatic cholesterol homeostasis
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EDC exposure in 3D genome memory in transgenerational obesity
EDC exposure in 3D genome memory in transgenerational obesity
A new study reveals that exposure of pregnant mice to an endocrine disrupting chemical, bisphenol A, induces multi-transge...
Serine slows diabetic neuropathy in mice
Serine slows diabetic neuropathy in mice
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A role for circulating levels of uridine in regulating hunger and food intake
A role for circulating levels of uridine in regulating hunger and food intake
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Metabolism and exercise: the skeletal muscle clock takes centre stage
Metabolism and exercise: the skeletal muscle clock takes centre stage
Circadian rhythms that influence mammalian homeostasis and overall health have received increasing interest over the past ...
A pipeline for identification and validation of brain targets for weight loss
A pipeline for identification and validation of brain targets for weight loss
The dorsal raphe nucleus (DRN) is emerging as a key regulator of food intake and energy expenditure but the molecular and ...
Variation in serotonin 2C receptor linked with obesity and behaviour
Variation in serotonin 2C receptor linked with obesity and behaviour
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Obesity induces epigenetic memory in innate immune cells
Obesity induces epigenetic memory in innate immune cells
Obesity is the second highest risk factor for age-related macular degeneration (AMD), the leading cause of loss of sight i...
Towards a better understanding of diabetes mellitus using organoid models
Towards a better understanding of diabetes mellitus using organoid models
Our understanding of diabetes mellitus has benefited from a combination of clinical investigations and work in model organ...
A fresh look at kisspeptin neuron synchronization
A fresh look at kisspeptin neuron synchronization
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
Applying the WHO global targets for diabetes mellitus
In 2022, the WHO created the first global targets for diabetes mellitus. The targets are that by 2030, 80% of people livin...
The gut microbiota in obesity and weight management: microbes as friends or foe?
The gut microbiota in obesity and weight management: microbes as friends or foe?
Obesity is caused by a long-term difference between energy intake and expenditure — an imbalance that is seemingly e...
New variant for monogenic obesity
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Knowledge in youth is wisdom in age: involving young people in research
“Adults have really boring ideas” is what we repeatedly learn from our participatory research with young peopl...
Monogenic diabetes mellitus hidden in autoantibody-negative diabetes mellitus
Monogenic diabetes mellitus hidden in autoantibody-negative diabetes mellitus
A considerable proportion of autoantibody-negative children with type 1 diabetes mellitus actually have monogenic forms of...
Food odour recognition adjusts systemic metabolism to nutrient availability
Food odour recognition adjusts systemic metabolism to nutrient availability
Food odour recognition is involved in the food anticipatory response. A study in Nature Metabolism describes how the olfac...
Precision medicine approach improves HbA1c outcomes in T2DM
Precision medicine approach improves HbA1c outcomes in T2DM
Utilizing precision medicine has the potential to improve outcomes in many diseases, however, the effect of precision medi...
A spectacular year for islet and stem cell transplantation
A spectacular year for islet and stem cell transplantation
The year 2022 has been notable for game-changing early progress in clinical trials with stem cell islets; durable and prom...
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