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NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe
BackgroundHepatocellular carcinoma (HCC) is the sixth most common malignancy globally and ranks third in terms of both mor...
A versatile microfluidic platform for malaria infection screening and Plasmodium species genotyping
eBioMedicineVolume 98, December 2023, 104898Author links open overlay panel, , , , , , , , SummaryBackgroundMalaria, a wid...
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster
eBioMedicineVolume 98, December 2023, 104878Author links open overlay panel, , , , , , , , , , , , , , , , , , , …SummaryB...
High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transcriptomic and in vitro studies
eBioMedicineVolume 98, December 2023, 104883Author links open overlay panel, , , , , , , , , , , SummaryBackgroundSystemic...
Childhood socioeconomic position and sex-specific trajectories of metabolic traits across early life: prospective cohort study
BackgroundSocioeconomic inequalities in cardiovascular disease risk begin early in life and are more pronounced in females...
Cellular mechanisms associated with sub-optimal immune responses to SARS-CoV-2 bivalent booster vaccination in patients with Multiple Myeloma
eBioMedicineVolume 98, December 2023, 104886Author links open overlay panel, , , , , , , , , , , , , , , , PVI/MM/Seronet ...
Cord blood DNA methylation signatures associated with preeclampsia are enriched for cardiovascular pathways: insights from the VDAART trial
eBioMedicineVolume 98, December 2023, 104890Author links open overlay panel, , , , , , , , , , SummaryBackgroundPreeclamps...
P. mirabilis-derived pore-forming haemolysin, HpmA drives intestinal alpha-synuclein aggregation in a mouse model of neurodegeneration
BackgroundRecent studies suggesting the importance of the gut-microbiome in intestinal aggregated alpha synuclein (α-syn) ...
Longitudinal lipidomic profiles during pregnancy and associations with neonatal anthropometry: findings from a multiracial cohort
BackgroundMaternal lipidomic profiling offers promise for characterizing lipid metabolites during pregnancy, but longitudi...
Anaerobic pathogens associated with OSA may contribute to pathophysiology via amino-acid depletion
eBioMedicineVolume 98, December 2023, 104891Author links open overlay panel, , , , , , , , , , , , , SummaryBackgroundThe ...
A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical data
BackgroundPancreatic Duct Adenocarcinoma (PDAC) screening can enable early-stage disease detection and long-term survival....
Association between gut microbiome-related metabolites and symptomatic hand osteoarthritis in two independent cohorts
eBioMedicineVolume 98, December 2023, 104892Author links open overlay panel, , , , , , , , , , , , , SummaryBackgroundSinc...
A prospective open label 2–8 year extension of the randomised controlled ICON trial on the long-term efficacy and safety of occipital nerve stimulation in medically intractable chronic cluster headache
BackgroundWe demonstrated in the randomised controlled ICON study that 48-week treatment of medically intractable chronic ...
Derivation of paediatric blood pressure percentiles from electronic health records
BackgroundIdentification of abnormal blood pressure (BP) in children requires normative data. We sought to examine the fea...
Natural infection by Zika virus but not DNA vaccination consistently elicits antibodies that compete with two potently neutralising monoclonal antibodies targeting distinct epitopes
eBioMedicineVolume 98, December 2023, 104875Author links open overlay panel, , , , , , , , , , , , , SummaryBackgroundAuto...
Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice
BackgroundHIV-1-associated immune activation drives CD4+ T cell depletion and the development of acquired immunodeficiency...
Super-enhancer driven SOX2 promotes tumor formation by chromatin re-organization in nasopharyngeal carcinoma
BackgroundNasopharyngeal carcinoma (NPC) is a malignant head and neck cancer with a high incidence in Southern China and S...
ACE2-independent SARS-CoV-2 virus entry through cell surface GRP78 on monocytes – evidence from a translational clinical and experimental approach
eBioMedicineVolume 98, December 2023, 104869Author links open overlay panel, , , , , , , , , SummaryBackgroundSARS-CoV-2 i...
Corrigendum to “Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease” [EBioMedicine 92 (2023) 104595]
eBioMedicineVolume 98, December 2023, 104876Author links open overlay panelHilde E. Lien a b, Hege F. Berg a b, Mari K. Ha...
Per- and polyfluoroalkyl substances (PFAS) exposure might be a risk factor for thyroid cancer
eBioMedicineVolume 98, December 2023, 104866Author links open overlay panelLi Jing, Zhixiong ShiShow morePrevious article ...
Is ipsilateral administration of COVID-19 vaccine boosters the optimal approach?
eBioMedicineVolume 98, December 2023, 104852Author links open overlay panelMildred A. Iro a, Matthew Buckland b cShow more...
A genomic perspective on climate change
eBioMedicineVolume 98, December 2023, 104871Author links open overlay panelFrancesca Forzano a, Chantal Babb de Villiers b...
Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses
BackgroundDrug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therape...
Differentiating the impacts of ambient temperature on pneumonia mortality of various infectious causes: a nationwide, individual-level, case-crossover study
eBioMedicineVolume 98, December 2023, 104854Author links open overlay panel, , , , , , , SummaryBackgroundIt remains unkno...
Clinical and electrophysiological features of SCN8A variants causing episodic or chronic ataxia
eBioMedicineVolume 98, December 2023, 104855Author links open overlay panel, , , , , , , , , , , , , , , , , , , …SummaryB...
Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study
BackgroundThe pattern of olfactory identification change in the early phases of dementing disorders is unclear. We aimed t...
Mouse models of diabetes-related ulcers: a systematic review and network meta-analysis
eBioMedicineVolume 98, December 2023, 104856Author links open overlay panel, , , , , SummaryBackgroundDiabetic foot ulcers...
Screening for mitochondrial function before use-routine liver assessment during hypothermic oxygenated perfusion impacts liver utilization
KeywordsDonation after circulatory deathHypothermic oxygenated perfusionFlavin mononucleotideLiver utilizationAbbreviation...
Mitochondrial injury during normothermic regional perfusion (NRP) and hypothermic oxygenated perfusion (HOPE) in a rodent model of DCD liver transplantation
BackgroundNormothermic regional perfusion (NRP) and hypothermic-oxygenated-perfusion (HOPE), were both shown to improve ou...
Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors
eBioMedicineVolume 98, December 2023, 104851Author links open overlay panel, , , , , , , , , , , , , , , , , SummaryBackgr...
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