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To Broaden or Not to Broaden? Answers on Appropriate Antimicrobial Escalations for Pediatric Hematopoietic Cell Transplant Patients Remain Out of Reach*
To Broaden or Not to Broaden? Answers on Appropriate Antimicrobial Escalations for Pediatric Hematopoietic Cell Transplant Patients Remain Out of Reach*
1 Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, The Children’s Hospital of Ph...
Measuring Expiratory Diaphragm Activity: An Electrifying Tool to Guide Positive End-Expiratory Pressure Strategy in Critically Ill Children?*
Measuring Expiratory Diaphragm Activity: An Electrifying Tool to Guide Positive End-Expiratory Pressure Strategy in Critically Ill Children?*
While normal, quiet expiration is a passive process with relaxation of the inspiratory respiratory muscles, it appears tha...
Discrimination by Design: Is It Time to Recalibrate Interpretation of Pulse Oximetry?*
Discrimination by Design: Is It Time to Recalibrate Interpretation of Pulse Oximetry?*
PULSE OXIMETRY; A PRIMER ON LIMITATIONS The pulse oximeter has revolutionized clinical care enabling inexpensiv...
Time of Death and Medication Dosing: Are We Asking the Right Questions?*
Time of Death and Medication Dosing: Are We Asking the Right Questions?*
1 Division of Pediatric Critical Care, Department of Pediatrics, George Washington University, Children’s National ...
Realizing Potential: Pediatric Extracorporeal Membrane Oxygenation Needs Common Adverse Event Definitions to Improve Outcomes*
Realizing Potential: Pediatric Extracorporeal Membrane Oxygenation Needs Common Adverse Event Definitions to Improve Outcomes*
1 Department of Cardiology, Boston Children’s Hospital, Boston, MA. 2 Department of Pediatrics, Harvard Medic...
Pediatric Intensive Care Development When Resources Are Scarce and Demand Is Potentially Very High*
Pediatric Intensive Care Development When Resources Are Scarce and Demand Is Potentially Very High*
Across the world, innovative and dedicated teams of healthcare workers are developing new pediatric critical care services...
Walking a Tightrope: Balancing Continuity for Long-Stay Patients and Wellness for Clinicians in an Ever-Evolving Landscape*
Walking a Tightrope: Balancing Continuity for Long-Stay Patients and Wellness for Clinicians in an Ever-Evolving Landscape*
The patient population of PICUs has evolved significantly over time, with decreasing mortality rates but increasing morbid...
Peripheral Glucocorticoid Metabolism Associated With Patient Severity in the PICU
Peripheral Glucocorticoid Metabolism Associated With Patient Severity in the PICU
1 Department of Pediatrics, Teine-Keijinkai Hospital, Sapporo, Japan. 2 Signaling in Cancer and Immunology, I...
Delirium: The Next Vital Sign in the PICU?*
Delirium: The Next Vital Sign in the PICU?*
Delirium is a syndrome of acute brain dysfunction occurring due to a complex interplay between disease-related factors, pr...
Through the Looking-Glass Door*
Through the Looking-Glass Door*
In Lewis Carroll’s Alice in Wonderland sequel, Through the Looking-Glass, Alice again enters a mythical world but this tim...
Consent for the Apnea Test: Asking the Wrong Question*
Consent for the Apnea Test: Asking the Wrong Question*
1 Division of Critical Care Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada. ...
Outcomes After Extracorporeal Membrane Oxygenation in Children With COVID-19*
Outcomes After Extracorporeal Membrane Oxygenation in Children With COVID-19*
1 Cardiothoracic Intensive Care Unit, National University Health System, Singapore. 2 Division of Pediatric C...
Tickle Me ECMO…Differences and Outcomes Unearthed for Kids Requiring Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Syndrome Coronavirus 2–Associated Disease*
Tickle Me ECMO…Differences and Outcomes Unearthed for Kids Requiring Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Syndrome Coronavirus 2–Associated Disease*
After 3 years into the pandemic, pediatricians have grown accustomed to the fact that severe acute respiratory syndrome co...
Unplanned Extubations Requiring Reintubation in Pediatric Critical Care: An Epidemiological Study
Unplanned Extubations Requiring Reintubation in Pediatric Critical Care: An Epidemiological Study
OBJECTIVES: Unplanned extubations are an infrequent but life-threatening adverse event in pediatr
von Willebrand Factor: The Canary in the Hemostasis Coal Mine of Extracorporeal Membrane Oxygenation?*
von Willebrand Factor: The Canary in the Hemostasis Coal Mine of Extracorporeal Membrane Oxygenation?*
An imbalance of hemostasis, manifest as hemorrhage, thrombosis or both, is commonly noted in critically ill adults and chi...
“How Was Work Today?”*
“How Was Work Today?”*
“How was work today?.” It is an innocent enough question—but not an easy one to answer when you work in intensive care. As...
Impaired Neurocognition, Quality of Life, and Behavior Following Multisystem Inflammatory Syndrome in Children: A Result of the Illness or the Pandemic?*
Impaired Neurocognition, Quality of Life, and Behavior Following Multisystem Inflammatory Syndrome in Children: A Result of the Illness or the Pandemic?*
Evaluation of long-term outcomes among survivors of pediatric critical illness has often lagged far behind the study of ac...
Pediatric Deterioration Detection Using Machine Learning*
Pediatric Deterioration Detection Using Machine Learning*
Departments of Biomedical Informatics and Pediatrics (Critical Care Medicine), University of Colorado School of Med...
Biology and Belonging*
Biology and Belonging*
“…I’ve set out to capture the Soul of This Human Race on film, in all its shades and from all four corners. So that we mig...
Initial Steps in Ascent to Assent for Pediatric Critical Care Research*
Initial Steps in Ascent to Assent for Pediatric Critical Care Research*
Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine...
Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock: Erratum
Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock: Erratum
Wolters Kluwer Health ...
The Association of Early Corticosteroid Therapy With Clinical and Health-Related Quality of Life Outcomes in Children With Septic Shock: Erratum
The Association of Early Corticosteroid Therapy With Clinical and Health-Related Quality of Life Outcomes in Children With Septic Shock: Erratum
Wolters Kluwer Health ...
The Classic Critical Care Conundrum Encounters Precision Medicine*
The Classic Critical Care Conundrum Encounters Precision Medicine*
For more than half a century clinicians and researchers have debated if patients benefit from or are harmed by adjunctive ...
Near-Infrared Spectrometry for Monitoring Patients With Complex Congenital Heart Disease Is Here to Stay*
Near-Infrared Spectrometry for Monitoring Patients With Complex Congenital Heart Disease Is Here to Stay*
The use of near-infrared spectrometry (NIRS) in the management of critically ill patients with congenital heart disease ha...
Balancing Fluid Resuscitation in Pediatric Sepsis*
Balancing Fluid Resuscitation in Pediatric Sepsis*
Fluid resuscitation remains a mainstay of sepsis treatment in children and adults. Historically, pediatric guidelines endo...
Development of a Stata Command for Pediatric Risk of Mortality Calculation
Development of a Stata Command for Pediatric Risk of Mortality Calculation
1 Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, ...
Avoid Making Assumptions About When Organ Donation Is Possible*
Avoid Making Assumptions About When Organ Donation Is Possible*
1 Division of Pediatric Critical Care, The Children’s Hospital of Philadelphia, Philadelphia, PA 2 Department...
Noninvasive Respiratory Support for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
Noninvasive Respiratory Support for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
OBJECTIVES: To develop evidence-based recommendations for the Second Pediatric Acute Lung Injury
Nonpulmonary Treatments for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
Nonpulmonary Treatments for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
OBJECTIVES: To provide an updated review of the literature on nonpulmonary treatments for pediatr
Leveraging Clinical Informatics and Data Science to Improve Care and Facilitate Research in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
Leveraging Clinical Informatics and Data Science to Improve Care and Facilitate Research in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
OBJECTIVES: The use of electronic algorithms, clinical decision support systems, and other clinic
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