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Association of Social Vulnerability and Access to Higher Quality Medicare Advantage Plans
Association of Social Vulnerability and Access to Higher Quality Medicare Advantage Plans
With more than half of all beneficiaries enrolled in Medicare Advantage (MA) plans, ensuring access to high-quality MA pla...
Having a More Compassionate Doctor Does Not Mean Patients Will Feel More Cared for: An Empirical Study
Having a More Compassionate Doctor Does Not Mean Patients Will Feel More Cared for: An Empirical Study
Compassion is central to healthcare. It is valued by both patients and physicians and predicts better outcomes for patient...
Added Value of Shaking Chills for Predicting Bacteremia in Patients with Suspected Infection
Added Value of Shaking Chills for Predicting Bacteremia in Patients with Suspected Infection
Detailed grading of chills is more useful for diagnosing bacteremia than simply classifying the presence or absence of chi...
Patient-Provider Interactions and Access to Prescription Medications Among Adults with Chronic Pain in the United States, 2023
Patient-Provider Interactions and Access to Prescription Medications Among Adults with Chronic Pain in the United States, 2023
Conflict of Interest: The authors declare that they do not have a c...
Patients Discharged “Against Medical Advice” More than Once: A Cross-Sectional Descriptive Analysis of a Vulnerable Population
Patients Discharged “Against Medical Advice” More than Once: A Cross-Sectional Descriptive Analysis of a Vulnerable Population
Patients who have been discharged “against medical advice” (AMA) are at increased risk of morbidity and mortal...
The Readability Study: A Randomised Trial of Health Information Written at Different Grade Reading Levels
The Readability Study: A Randomised Trial of Health Information Written at Different Grade Reading Levels
Despite increasing attention on health literacy and the inclusion of grade reading level recommendations in guidelines, it...
Reasoning on Rounds Volume 2: a Framework for Teaching Management Reasoning in the Inpatient Setting
Reasoning on Rounds Volume 2: a Framework for Teaching Management Reasoning in the Inpatient Setting
Management reasoning (MR) is a key domain of clinical reasoning that is distinct from the more heavily studied and taught ...
Comparison of Management and Outcomes of Hip Fractures Among Low- and High-Income Patients in Six High-Income Countries
Comparison of Management and Outcomes of Hip Fractures Among Low- and High-Income Patients in Six High-Income Countries
There is a perception that income-based disparities are present in most countries but may differ in magnitude. However, th...
Perspectives of In-Hospital Intramuscular Naltrexone and Oral Medications for Alcohol Use Disorder: A Study of Addiction Clinicians and Hospitalized Patients
Perspectives of In-Hospital Intramuscular Naltrexone and Oral Medications for Alcohol Use Disorder: A Study of Addiction Clinicians and Hospitalized Patients
Alcohol-related hospitalizations are rising; however, medications for alcohol use disorder (M-AUD) are underprescribed des...
Effects of Blood Flow Restriction Combined with Aerobic Stepping Exercise in Sarcopenia: A Study Protocol for a Randomized Clinical Trial
Effects of Blood Flow Restriction Combined with Aerobic Stepping Exercise in Sarcopenia: A Study Protocol for a Randomized Clinical Trial
Effects of Blood Flow Restriction Combined with Aerobic Stepping Exercise in Sarcopenia: A Study Protocol for a Randomized...
Retrospective Analysis of Sacubitril/Valsartan vs Benazepril for Treating Heart Failure Following Acute Myocardial Infarction
Retrospective Analysis of Sacubitril/Valsartan vs Benazepril for Treating Heart Failure Following Acute Myocardial Infarction
Retrospectively comparing efficacy of Sacubitril/Valsartan and Benazepril in the treatment of heart failure in patients fo...
Identification and Validation of Ferroptosis Related Genes in Ischemic Stroke and Its Effect on the Peripheral Immune Landscape
Identification and Validation of Ferroptosis Related Genes in Ischemic Stroke and Its Effect on the Peripheral Immune Landscape
This study aims to identify ferroptosis-related genes in ischemic stroke and examine their role in shaping the peripheral ...
Risk Prediction Model for Isoniazid Dosing in Tuberculosis Meningitis Patients in Southwest China
Risk Prediction Model for Isoniazid Dosing in Tuberculosis Meningitis Patients in Southwest China
The prognosis of meningitis is often related to disease severity and early therapeutic intervention in Southwest China.
Self-Reported Time-at-Bedside and Its Association with In-Training Examination Scores of Residents in Japan
Self-Reported Time-at-Bedside and Its Association with In-Training Examination Scores of Residents in Japan
Time-at-bedside plays a central role in clinical medicine. However, the amount of time Japanese clinical residents spend a...
Self-administration of aspirin for acute chest pain—Does it prevent premature cardiovascular mortality?
Self-administration of aspirin for acute chest pain—Does it prevent premature cardiovascular mortality?
Aspirin as a class I guideline recommended medical treatment for acute coronary syndrome has been establ...
Frameshift mutation spectra overlap between constitutional mismatch repair deficiency tumors and Lynch syndrome tumors
Research LetterOncology Open Access | 10.1172/JCI185999 Yurong Song, Ryan N. Baugher, ...
Neutrophil Gelatinase-Associated Lipocalin and Interleukin-18 in the Prediction of Acute Kidney Injury in Sepsis Patients
Neutrophil Gelatinase-Associated Lipocalin and Interleukin-18 in the Prediction of Acute Kidney Injury in Sepsis Patients
Assessing predictive value of blood neutrophil gelatinase-associated lipocalin and interleukin-18 in predicting the onset ...
Relative Factors Analysis of the Occurrence and Location of Intratracheal Granuloma Following Tracheotomy
Relative Factors Analysis of the Occurrence and Location of Intratracheal Granuloma Following Tracheotomy
Considering the occurrence and location of intratracheal granulomas following tracheotomy, it is imperative that clinician...
Sex-Biased CD3ζ 3ʹ-UTR SNP Increased Incidence Risk in Aplastic Anemia
Sex-Biased CD3ζ 3ʹ-UTR SNP Increased Incidence Risk in Aplastic Anemia
Analyzing whether CD3ζ 3'-UTR SNPs were associated with AA susceptibility and influenced CD3ζ protein level. Rea...
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
Sex as a biological variable. Our study examined male and female animals, and similar findings are reported for both sexe...
Interleukin 10 drives Staphylococcus aureus imprinting and vaccine failure in murine models via antibody glycosylation
Human exposure to S. aureus triggers the development of immunity, imprinting an adaptive immune response that is lacking ...
Pathobiont-driven antibody sialylation through IL-10 undermines vaccination
Research ArticleImmunologyInfectious disease Open Access | 10.1172/JCI179563 Chih-Ming Tsai,1...
Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors
Research ArticleNephrology Open Access | 10.1172/JCI180347 Silvana Bazua-Valenti,1,2,3 Ma...
DNA-PK inhibition enhances neoantigen diversity and increases T cell responses to immunoresistant tumors
Combination DNA-PK inhibition plus immune adjuvants drive melanoma regression via a CD8+ T cell–dependent mechanism. We p...
Attenuated kidney oxidative metabolism in young adults with type 1 diabetes
Clinical MedicineEndocrinologyMetabolism Open Access | 10.1172/JCI183984 Ye Ji Choi,1,2 G...
Immune-molecular interactions in high-grade serous ovarian cancer distinguish long-term survivors
BACKGROUND Despite an overall poor prognosis, about 15% of patients with advanced-stage tubo-ovarian high-grade serous ca...
Balancing immune response: SHP1 controls neutrophil activation in inflamed lungs
Src homology region 2 domain-containing phosphatase-1 (SHP1), a cytosolic tyrosine phosphatase, emerges as a crucial nega...
Evi1 governs Kdm6b-mediated histone demethylation to regulate the Laptm4b-driven mTOR pathway in hematopoietic progenitor cells
Research ArticleHematology Open Access | 10.1172/JCI173403 Qiong Wu,1,2 Chunjie Yu,2 ...
Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels
Research ArticleOncology Open Access | 10.1172/JCI170953 Saptarshi Sinha,1 Brennan W. Cal...
Nicotinamide and pyridoxine stimulate muscle stem cell expansion and enhance regenerative capacity during aging
Research ArticleMuscle biologyStem cells Open Access | 10.1172/JCI163648 Sara Ancel,1,2 J...
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