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Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19
SARS-CoV-2 has been shown to predominantly infect the airways and the respiratory tract and too often have an unpredictabl...
Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands
Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands
Salivary stones, also known as sialoliths, are formed in a pathological situation in the salivary glands. So far, neither ...
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
Gallbladder cancer (GBC) is a lethal cancer with a poor prognosis. The lack of specific and sensitive biomarkers results i...
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study
Aspiration pneumonia (AP), which is a major cause of death in the elderly, does present with typical symptoms in the early...
Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children
Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma with poor prognosis in children. The 5-year survival rate fo...
Changes of serum IgG glycosylation patterns in rheumatoid arthritis
Changes of serum IgG glycosylation patterns in rheumatoid arthritis
RA is a common chronic and systemic autoimmune disease, and the diagnosis is based significantly on autoantibody detection...
Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation
Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation
Inflammatory bowel disease (IBD) encompasses a group of chronic relapsing disorders which include ulcerative colitis (UC) ...
Are the results from a multiplex proteomic assay and a conventional immunoassay for NT-proBNP and GDF-15 comparable?
Are the results from a multiplex proteomic assay and a conventional immunoassay for NT-proBNP and GDF-15 comparable?
We aimed to compare absolute plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) and growth diff...
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study
Continuous renal replacement therapy (CRRT) has been considered as an adjuvant therapy for sepsis. However, the novel biom...
Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS
Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS
Spermatozoa have the task of delivering an intact paternal genome to the oocyte and supporting successful embryo developme...
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics
Non-invasive detection of blood-based markers is a critical clinical need. Plasma has become the main sample type for clin...
A proteomic profile of the healthy human placenta
A proteomic profile of the healthy human placenta
The placenta remains one of the least studied organs within the human body. Yet, placental dysfunction has been associated...
LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy
LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy
Immunoglobulin A nephropathy (IgAN), a globally common primary chronic glomerulopathy, is one of the leading causes of end...
Novel plasma protein biomarkers from critically ill sepsis patients
Novel plasma protein biomarkers from critically ill sepsis patients
Despite the high morbidity and mortality associated with sepsis, the relationship between the plasma proteome and clinical...
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach
The progression of chronic pancreatitis (CP), an inflammatory disease of the pancreas, causes pancreatic stones to form wi...
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection
Global high-throughput phosphoproteomic profiling is increasingly being applied to cancer specimens to identify the oncoge...
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion
Recurrent spontaneous abortion (RSA) is a common and complicated pregnancy-related disease that lacks a suitable biomarker...
Proteomic profiling of end-stage COVID-19 lung biopsies
Proteomic profiling of end-stage COVID-19 lung biopsies
The outbreak of a novel coronavirus (SARS-CoV-2) in 2019 led to a worldwide pandemic, which remains an integral p...
Proteomics profiles of blood glucose-related proteins involved in a Chinese longevity cohort
Proteomics profiles of blood glucose-related proteins involved in a Chinese longevity cohort
High blood glucose level is one of the main characteristics of diabetes mellitus. Based on previous studies, it is specula...
Quantitative proteomics identified circulating biomarkers in lung adenocarcinoma diagnosis
Quantitative proteomics identified circulating biomarkers in lung adenocarcinoma diagnosis
Lung cancer (LC) is a common malignant tumor with a high incidence and poor prognosis. Early LC could be cured, but the 5-...
Glycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers
Glycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers
Circulating biomarkers play important roles in diagnosis of malignant tumors. N-glycosylation is an important post-transla...
Comparison of intact protein and digested peptide techniques for high throughput proteotyping of ApoE
Comparison of intact protein and digested peptide techniques for high throughput proteotyping of ApoE
Apolipoprotein E (ApoE) genotyping has been shown to have diagnostic value in the evaluation of cardiovascular diseases an...
Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals
Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals
Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, QC, CanadaGuillaume Butler-Laporte, Chen-Yang ...
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies
Regulatory degradation of intracellular proteins plays an essential role in most biological processes, particularly in the...
Determination of temporal reproducibility and variability of cancer biomarkers in serum and EDTA plasma samples using a proximity extension assay
Determination of temporal reproducibility and variability of cancer biomarkers in serum and EDTA plasma samples using a proximity extension assay
Proximity extension assay (PEA) is a novel antibody-based proteomic technology. Sparse data have been published concerning...
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation
Most patients infected with SARS-CoV-2 display mild symptoms with good prognosis, while 20% of patients suffer from severe...
Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma
Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma
The identification of differentially expressed tumor-associated proteins and genomic alterations driving neoplasia is crit...
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study
BTBD7_hsa_circ_0000563 is a novel circRNA and contains conserved binding sites with RNA-binding proteins. However, BTBD7_h...
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals
Severe COVID-19 leads to important changes in circulating immune-related proteins. To date it has been difficult to unders...
Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues
Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues
Optimal cytoreduction to no residual disease (R0) correlates with improved disease outcome for high-grade serous ovarian c...
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