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Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis
Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis
Information on the microbiome's human pathways and active members that can affect SARS-CoV-2 susceptibility and pathog...
Aqueous humor proteomics analyzed by bioinformatics and machine learning in PDR cases versus controls
Aqueous humor proteomics analyzed by bioinformatics and machine learning in PDR cases versus controls
To comprehend the complexities of pathophysiological mechanisms and molecular events that contribute to proliferative diab...
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning
COVID-19 is a complex, multi-system disease with varying severity and symptoms. Identifying changes in critically ill COVI...
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics
Traumatic brain injury (TBI) often results in diverse molecular responses, challenging traditional proteomic studies that ...
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Cardio-metabolic disorders (CMDs) are common in aging people and are pivotal risk factors for cardiovascular diseases (CVD...
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas
Adamantinomatous craniopharyngiomas (ACPs) are rare benign epithelial tumours with high recurrence and poor prognosis. Bio...
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies
Certain demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycopr...
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology
Colorectal Cancer (CRC) is a prevalent form of cancer, and the effectiveness of the main postoperative chemotherapy treatm...
Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA
Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA
Clinical samples are irreplaceable, and their transformation into searchable and reusable digital biobanks is critical for...
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors
Metastatic pancreatic adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States, with ...
Neat plasma proteomics: getting the best out of the worst
Neat plasma proteomics: getting the best out of the worst
Plasma proteomics holds immense potential for clinical research and biomarker discovery, serving as a non-invasive "l...
Proteomics of prostate cancer serum and plasma using low and high throughput approaches
Proteomics of prostate cancer serum and plasma using low and high throughput approaches
Despite progress, MS-based proteomics in biofluids, especially blood, faces challenges such as dynamic range and throughpu...
Proteomic analysis of breast cancer based on immune subtypes
Proteomic analysis of breast cancer based on immune subtypes
Immunotherapy is applied to breast cancer to resolve the limitations of survival gain in existing treatment modalities. Wi...
Highly sensitive therapeutic drug monitoring of infliximab in serum by targeted mass spectrometry in comparison to ELISA data
Highly sensitive therapeutic drug monitoring of infliximab in serum by targeted mass spectrometry in comparison to ELISA data
Presently, antibody concentration measurements for patients undergoing treatment are predominantly determined by ELISA, wh...
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling
In persons with dyslipidemia, a high residual risk of cardiovascular disease remains despite lipid lowering therapy. Curre...
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort
Hypertension is an important public health priority with a high prevalence in Africa. It is also an independent risk facto...
Recent progress in mass spectrometry-based urinary proteomics
Recent progress in mass spectrometry-based urinary proteomics
Serum or plasma is frequently utilized in biomedical research; however, its application is impeded by the requirement for ...
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients
SARS-CoV-2 infection triggers extensive host immune reactions, leading to severe diseases in certain individuals. However,...
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers
Routine measurement of cancer biomarkers is performed for early detection, risk classification, and treatment monitoring, ...
Mapping three-dimensional intratumor proteomic heterogeneity in uterine serous carcinoma by multiregion microsampling
Mapping three-dimensional intratumor proteomic heterogeneity in uterine serous carcinoma by multiregion microsampling
Although uterine serous carcinoma (USC) represents a small proportion of all uterine cancer cases, patients with this aggr...
Kinase inhibitor pulldown assay (KiP) for clinical proteomics
Kinase inhibitor pulldown assay (KiP) for clinical proteomics
Protein kinases are frequently dysregulated and/or mutated in cancer and represent essential targets for therapy. Accurate...