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Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities
COVID19 is a pandemic that has affected millions around the world since March 2020. While many patients recovered complete...
SPOT: spatial proteomics through on-site tissue-protein-labeling
SPOT: spatial proteomics through on-site tissue-protein-labeling
Spatial proteomics seeks to understand the spatial organization of proteins in tissues or at different subcellular localiz...
Identification of novel proteins in inflammatory bowel disease based on the gut-brain axis: a multi-omics integrated analysis
Identification of novel proteins in inflammatory bowel disease based on the gut-brain axis: a multi-omics integrated analysis
The gut-brain axis has garnered increasing attention, with observational studies suggesting its involvement in the disease...
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer
The diagnosis and treatment of colorectal cancer (CRC), especially metastatic colorectal cancer (mCRC), is a major priorit...
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, and the prevalence of CVDs increases markedly wit...
Biomarker discovery in progressive supranuclear palsy from human cerebrospinal fluid
Biomarker discovery in progressive supranuclear palsy from human cerebrospinal fluid
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder often misdiagnosed as Parkinson’s Disease (PD) ...
Research biopsies in kidney transplantation: an evaluation of surgical techniques and optimal tissue mass allowing molecular and histological analyses
Research biopsies in kidney transplantation: an evaluation of surgical techniques and optimal tissue mass allowing molecular and histological analyses
Research biopsies have great potential to advance scientific knowledge by helping to establish predictors of favourable or...
Using established biorepositories for emerging research questions: a feasibility study
Using established biorepositories for emerging research questions: a feasibility study
Proteomics and metabolomics offer substantial potential for advancing kidney transplant research by providing versatile op...
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides
Mycosis fungoides (MF) is the most common type of cutaneous T cell lymphoma. As the early clinical manifestations of MF ar...
Quantitative proteomics reveals serum proteome alterations during metastatic disease progression in breast cancer patients
Quantitative proteomics reveals serum proteome alterations during metastatic disease progression in breast cancer patients
Tumor recurrence and metastatic progression remains the leading cause for breast cancer related mortalities. However, the ...
Proteomic profile and predictive markers of outcome in patients with subarachnoid hemorrhage
Proteomic profile and predictive markers of outcome in patients with subarachnoid hemorrhage
The molecular mechanisms underlying development of posthemorrhagic hydrocephalus (PHH) following subarachnoid hemorrhage (...
Effect of dynamic exclusion and the use of FAIMS, DIA and MALDI-mass spectrometry imaging with ion mobility on amyloid protein identification
Effect of dynamic exclusion and the use of FAIMS, DIA and MALDI-mass spectrometry imaging with ion mobility on amyloid protein identification
Amyloidosis is a disease characterized by local and systemic extracellular deposition of amyloid protein fibrils where its...
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka
Characterization of the host response in cutaneous leishmaniasis (CL) through proteome profiling has gained limited insigh...
Resistin as a potential diagnostic biomarker for sepsis: insights from DIA and ELISA analyses
Resistin as a potential diagnostic biomarker for sepsis: insights from DIA and ELISA analyses
The primary objective of this investigation is to systematically screen and identify differentially expressed proteins (DE...
A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens
A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens
Understanding the interplay of the proteome and the metabolome helps to understand cellular regulation and response. To en...
ESF1 and MIPEP proteins promote estrogen receptor-positive breast cancer proliferation and are associated with patient prognosis
ESF1 and MIPEP proteins promote estrogen receptor-positive breast cancer proliferation and are associated with patient prognosis
Estrogen receptor-positive (ER+) breast cancer accounts for two-thirds of all breast cancers, and its early and late recur...
Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF)
Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF)
The development of breast cancer has been mainly reported in women who have reached the post-menopausal stage; therefore, ...
Proteomic profiling of prostate cancer reveals molecular signatures under antiandrogen treatment
Proteomic profiling of prostate cancer reveals molecular signatures under antiandrogen treatment
Tumorigenesis and progression of prostate cancer (PCa) are indispensably dependent on androgen receptor (AR). Antiandrogen...
Frontiers in plasma proteome profiling platforms: innovations and applications
Frontiers in plasma proteome profiling platforms: innovations and applications
Biomarkers play a crucial role in advancing precision medicine by enabling more targeted and individualized approaches to ...
Identification of brain-enriched proteins in CSF as biomarkers of relapsing remitting multiple sclerosis
Identification of brain-enriched proteins in CSF as biomarkers of relapsing remitting multiple sclerosis
Multiple sclerosis (MS) is a clinically and biologically heterogenous disease with currently unpredictable progression and...
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers
Gliomas are aggressive malignant tumors, with poor prognosis. There is an unmet need for the discovery of new, non-invasiv...
Elevated level of multibranched complex glycan reveals an allergic tolerance status
Elevated level of multibranched complex glycan reveals an allergic tolerance status
Allergen immunotherapy (AIT) is the only disease-modifying therapy that can achieve immune tolerance in patients through l...
Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis
Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis
Avascular necrosis (AVN) is a medical condition characterized by the destruction of bone tissue due to a diminished blood ...
Differentiation between descending thoracic aortic diseases using machine learning and plasma proteomic signatures
Differentiation between descending thoracic aortic diseases using machine learning and plasma proteomic signatures
Descending thoracic aortic aneurysms and dissections can go undetected until severe and catastrophic, and few clinical ind...
Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis
Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis
Information on the microbiome's human pathways and active members that can affect SARS-CoV-2 susceptibility and pathog...
Aqueous humor proteomics analyzed by bioinformatics and machine learning in PDR cases versus controls
Aqueous humor proteomics analyzed by bioinformatics and machine learning in PDR cases versus controls
To comprehend the complexities of pathophysiological mechanisms and molecular events that contribute to proliferative diab...
Correlation between small-cell lung cancer serum protein/peptides determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and chemotherapy efficacy
Correlation between small-cell lung cancer serum protein/peptides determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and chemotherapy efficacy
Currently, no effective measures are available to predict the curative efficacy of small-cell lung cancer (SCLC) chemother...
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning
COVID-19 is a complex, multi-system disease with varying severity and symptoms. Identifying changes in critically ill COVI...
Evaluation of a proteomic signature coupled with the kidney failure risk equation in predicting end stage kidney disease in a chronic kidney disease cohort
Evaluation of a proteomic signature coupled with the kidney failure risk equation in predicting end stage kidney disease in a chronic kidney disease cohort
The early identification of patients at high-risk for end-stage renal disease (ESRD) is essential for providing optimal ca...
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics
Traumatic brain injury (TBI) often results in diverse molecular responses, challenging traditional proteomic studies that ...
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