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Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins
Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins
The molecular pathology of diffuse large B cell lymphoma (DLBCL) has been extensively studied. Among DLBCL subtypes, the p...
Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy
Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy
Differentiating between a normal intrauterine pregnancy (IUP) and abnormal conditions including early pregnancy loss (EPL)...
New mechanisms and biomarkers of lymph node metastasis in cervical cancer: reflections from plasma proteomics
New mechanisms and biomarkers of lymph node metastasis in cervical cancer: reflections from plasma proteomics
Lymph node metastasis (LNM) and lymphatic vasculature space infiltration (LVSI) in cervical cancer patients indicate a poo...
Correction to: Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis
Correction to: Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis
Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis
Multiple sclerosis (MS) remains a highly unpredictable disease. Many hope that fluid biomarkers may contribute to better s...
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various disciplines of laboratory medicine t...
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases
Human plasma contains a wide variety of circulating proteins. These proteins can be important clinical biomarkers in disea...
Identification of SARS-CoV-2 biomarkers in saliva by transcriptomic and proteomics analysis
Identification of SARS-CoV-2 biomarkers in saliva by transcriptomic and proteomics analysis
The detection of SARS-CoV-2 biomarkers by real time PCR (rRT-PCR) has shown that the sensitivity of the test is negatively...
Comparative proteomics analysis in different stages of urothelial bladder cancer for identification of potential biomarkers: highlighted role for antioxidant activity
Comparative proteomics analysis in different stages of urothelial bladder cancer for identification of potential biomarkers: highlighted role for antioxidant activity
Non-muscle-invasive bladder cancer (NMIBC) has a high recurrence rate and muscle-invasive bladder cancer (MIBC) has unfavo...
Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus
Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a clinically and biologically heterogenous autoimmune disease. We aimed to investiga...
Associations of circulating proteins with lipoprotein profiles: proteomic analyses from the OmniHeart randomized trial and the Atherosclerosis Risk in Communities (ARIC) Study
Associations of circulating proteins with lipoprotein profiles: proteomic analyses from the OmniHeart randomized trial and the Atherosclerosis Risk in Communities (ARIC) Study
Within healthy dietary patterns, manipulation of the proportion of macronutrient can reduce CVD risk. However, the biologi...
VCAM-1 complements CA-125 in detecting recurrent ovarian cancer
VCAM-1 complements CA-125 in detecting recurrent ovarian cancer
Close to three-quarters of ovarian cancer cases are frequently diagnosed at an advanced stage, with more than 70%...
Identification of ORM1, vWF, SPARC, and PPBP as immune-related proteins involved in immune thrombocytopenia by quantitative LC-MS/MS
Identification of ORM1, vWF, SPARC, and PPBP as immune-related proteins involved in immune thrombocytopenia by quantitative LC-MS/MS
Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by loss of immune tolerance to platelet autoant...
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers
Molecular components in blood, such as proteins, are used as biomarkers to detect or predict disease states, guide clinica...
Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?
Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?
Unpredictable treatment responses have been an obstacle for the successful management of rheumatoid arthritis. Although nu...
Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis
Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis
IgA nephropathy (IgAN) and IgA vasculitis with nephritis (IgAVN) are related glomerular diseases characterized by marked s...
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips
Sepsis is a common worldwide health condition with high mortality. It is caused by a dysregulated immune response to the p...
Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry
Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry
Halting progression of chronic kidney disease (CKD) to established end stage kidney disease is a major goal of global heal...
Correction to: Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection
Correction to: Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer
Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer
Colorectal cancer (CRC) is one of the major causes of cancer-related death worldwide. Although commercial biomarkers of CR...
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets
As a rare pathologic subtype, small cell carcinoma of the cervix (SCCC) is characterized by extensive aggressiveness and r...
Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients
Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients
Proteomic analysis of human plasma by LC–ESI–MS/MS has discovered a limited number of new cellular protein bio...
Discovery of novel glioma serum biomarkers by proximity extension assay
Discovery of novel glioma serum biomarkers by proximity extension assay
Gliomas are among the most malignant tumors, with a very poor prognosis. Early diagnosis is highly desirable since it can ...
An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples
An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples
Clinical bronchoalveolar lavage fluid (BALF) samples are rich in biomolecules, including proteins, and useful for molecula...
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19
SARS-CoV-2 has been shown to predominantly infect the airways and the respiratory tract and too often have an unpredictabl...
Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands
Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands
Salivary stones, also known as sialoliths, are formed in a pathological situation in the salivary glands. So far, neither ...
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
Gallbladder cancer (GBC) is a lethal cancer with a poor prognosis. The lack of specific and sensitive biomarkers results i...
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study
Aspiration pneumonia (AP), which is a major cause of death in the elderly, does present with typical symptoms in the early...
Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children
Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma with poor prognosis in children. The 5-year survival rate fo...
Changes of serum IgG glycosylation patterns in rheumatoid arthritis
Changes of serum IgG glycosylation patterns in rheumatoid arthritis
RA is a common chronic and systemic autoimmune disease, and the diagnosis is based significantly on autoantibody detection...
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