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Targeting Non-Coding RNA for CNS Injuries: Regulation of Blood-Brain Barrier Functions
Targeting Non-Coding RNA for CNS Injuries: Regulation of Blood-Brain Barrier Functions
Central nervous system (CNS) injuries are the most common cause of death and disability around the world. The blood-brain ...
Biomarkers: Role and Scope in Neurological Disorders
Biomarkers: Role and Scope in Neurological Disorders
Neurological disorders pose a great threat to social health and are a major cause for mortality and morbidity. Effective d...
ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions
ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions
Activating transcription factor 6 (ATF6) is an endoplasmic reticulum (ER) stress-regulated transcription factor that induc...
Regulatory Basis of Adipokines Leptin and Adiponectin in Epilepsy: from Signaling Pathways to Glucose Metabolism
Regulatory Basis of Adipokines Leptin and Adiponectin in Epilepsy: from Signaling Pathways to Glucose Metabolism
Epilepsy is a common and severe neurological disorder in which impaired glucose metabolism leads to changes in neuronal ex...
Modulation of Synaptic Plasticity Genes Associated to DNA Damage in a Model of Huntington’s Disease
Modulation of Synaptic Plasticity Genes Associated to DNA Damage in a Model of Huntington’s Disease
Huntington’s disease (HD) is a disease characterized by the progressive degeneration of nerve cells in the brain. DN...
β-lapachone-mediated WST1 Reduction as Indicator for the Cytosolic Redox Metabolism of Cultured Primary Astrocytes
β-lapachone-mediated WST1 Reduction as Indicator for the Cytosolic Redox Metabolism of Cultured Primary Astrocytes
Electron cycler-mediated extracellular reduction of the water-soluble tetrazolium salt 1 (WST1) is frequently used as tool...
Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges
Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges
Central nervous system (CNS)-related conditions are currently the leading cause of disability worldwide, posing a signific...
TRAF4 Silencing Induces Cell Apoptosis and Improves Retinoic Acid Sensitivity in Human Neuroblastoma
TRAF4 Silencing Induces Cell Apoptosis and Improves Retinoic Acid Sensitivity in Human Neuroblastoma
Neuroblastoma (NB) is a pediatric malignancy that arises in the peripheral nervous system, and the prognosis in the high-r...
NMDA Receptor Activation and Ca2+/PKC Signaling in Nicotine-Induced GABA Transport Shift in Embryonic Chick Retina
NMDA Receptor Activation and Ca2+/PKC Signaling in Nicotine-Induced GABA Transport Shift in Embryonic Chick Retina
Nicotinic receptors are present in the retina of different vertebrates, and in the chick retina, it is present during earl...
Curcumin Ameliorates Neurobehavioral Deficits in Ambient Dusty Particulate Matter-Exposure Rats: The Role of Oxidative Stress
Curcumin Ameliorates Neurobehavioral Deficits in Ambient Dusty Particulate Matter-Exposure Rats: The Role of Oxidative Stress
It has been consistently found that exposure to ambient air pollution, such as particulate matter (PM), results in cogniti...
Genome-wide Analysis of Histone H3 Lysine 27 Trimethylation Profiles in Sciatic Nerve of Chronic Constriction Injury Rats
Genome-wide Analysis of Histone H3 Lysine 27 Trimethylation Profiles in Sciatic Nerve of Chronic Constriction Injury Rats
The histone H3 lysine 27 trimethylation (H3K27me3) is one of the most important chromatin modifications, which is associat...
Emerging Targets for Modulation of Immune Response and Inflammation in Stroke
Emerging Targets for Modulation of Immune Response and Inflammation in Stroke
The inflammatory and immunological responses play a significant role after stroke. The innate immune activation stimulated...
Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis
Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis
Ischemic stroke (IS) is the most common type of stroke and the second leading cause of death overall. Neural stem cells pl...
Active Clinical Trials in Hepatic Encephalopathy: Something Old, Something New and Something Borrowed
Active Clinical Trials in Hepatic Encephalopathy: Something Old, Something New and Something Borrowed
Hepatic encephalopathy (HE) is a potentially reversible neurocognitive syndrome that occurs in patients with acute or chro...
Cellular Localization and Distribution of TGF-β1, GDNF and PDGF-BB in the Adult Primate Central Nervous System
Cellular Localization and Distribution of TGF-β1, GDNF and PDGF-BB in the Adult Primate Central Nervous System
The available data on the localization of transforming growth factor beta1 (TGF-β1), glial cell line-derived neurotro...
Delayed Outgrowth in Response to the BDNF and Altered Synaptic Proteins in Neurons From SHR Rats
Delayed Outgrowth in Response to the BDNF and Altered Synaptic Proteins in Neurons From SHR Rats
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivi...
Cannabidiol Recovers Dopaminergic Neuronal Damage Induced by Reserpine or α-synuclein in Caenorhabditis elegans
Cannabidiol Recovers Dopaminergic Neuronal Damage Induced by Reserpine or α-synuclein in Caenorhabditis elegans
Progressive neurodegenerative disorders such as Parkinson Disease (PD) lack curative or long-term treatments. At the same ...
Epigenetic Up-Regulation of ADAMTS4 in Sympathetic Ganglia is Involved in the Maintenance of Neuropathic Pain Following Nerve Injury
Epigenetic Up-Regulation of ADAMTS4 in Sympathetic Ganglia is Involved in the Maintenance of Neuropathic Pain Following Nerve Injury
Sympathetic axonal sprouting into dorsal root ganglia is a major phenomenon implicated in neuropathic pain, and sympatheti...
Brain Leukocytes as the Potential Therapeutic Target for Post-COVID-19 Brain Fog
Brain Leukocytes as the Potential Therapeutic Target for Post-COVID-19 Brain Fog
After recovering from the acute phase of coronavirus disease 2019 (COVID-19), many patients struggle with additional sympt...
Leptin Attenuates Fear Memory by Inhibiting Astrocytic NLRP3 Inflammasome in Post-traumatic Stress Disorder Model
Leptin Attenuates Fear Memory by Inhibiting Astrocytic NLRP3 Inflammasome in Post-traumatic Stress Disorder Model
Accumulating evidence suggests that the activation of nucleotide-binding domain and leucine-rich repeat protein-3 (NLRP3) ...
Overview Article Astrocytes as Initiators of Epilepsy
Overview Article Astrocytes as Initiators of Epilepsy
Astrocytes play a dual role in the brain. On the one hand, they are active signaling partners of neurons and can for insta...