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miR-210-5p Promotes Pulmonary Hypertension by Blocking ATP2A2
miR-210-5p Promotes Pulmonary Hypertension by Blocking ATP2A2
Aberrant expression of ATPase sarcoplasmic/endoplasmic retic Ca2+ transporting 2 (ATP2A2) has attracted attention fo...
Outcomes With Hybrid Catheter-Directed Therapy Compared With Aspiration Thrombectomy for Patients With Intermediate-High Risk Pulmonary Embolism
Outcomes With Hybrid Catheter-Directed Therapy Compared With Aspiration Thrombectomy for Patients With Intermediate-High Risk Pulmonary Embolism
Intermediate-high-risk pulmonary embolism (IHR PE) is a challenging form of embolism obstruction that causes right ventric...
Impairment of Vascular Homeostasis in Acute Heart Failure: Enter the Monocyte?
Impairment of Vascular Homeostasis in Acute Heart Failure: Enter the Monocyte?
The stimulus for this Editorial Comment was provided by the recent publication in Cardiovascular Drugs and Therapy of an o...
Gab1 Overexpression Attenuates Susceptibility to Ventricular Arrhythmias in Pressure Overloaded Heart Failure Mouse Hearts
Gab1 Overexpression Attenuates Susceptibility to Ventricular Arrhythmias in Pressure Overloaded Heart Failure Mouse Hearts
Grb2 associated binding protein 1 (Gab1) is an adaptor protein that is important for intracellular signal transduction whi...
Inadequate Use of Newer Treatments and Glycemic Control by Cardiovascular Risk and Sociodemographic Groups in US Adults with Diabetes in the NIH Precision Medicine Initiative All of Us Research Program
Inadequate Use of Newer Treatments and Glycemic Control by Cardiovascular Risk and Sociodemographic Groups in US Adults with Diabetes in the NIH Precision Medicine Initiative All of Us Research Program
Data are limited on sodium glucose co-transport 2 inhibitors (SGLT2-is) and glucagon-like peptide-1 receptor agonists (GLP...
Machine Learning-Based Model for Predicting Prolonged Mechanical Ventilation in Patients with Congestive Heart Failure
Machine Learning-Based Model for Predicting Prolonged Mechanical Ventilation in Patients with Congestive Heart Failure
Mechanical ventilation (MV) is widely used to relieve respiratory failure in patients with congestive heart failure (CHF)....
Cardiovascular Mechano-Epigenetics: Force-Dependent Regulation of Histone Modifications and Gene Regulation
Cardiovascular Mechano-Epigenetics: Force-Dependent Regulation of Histone Modifications and Gene Regulation
The local mechanical microenvironment impacts on the cell behavior. In the cardiovascular system, cells in both the heart ...
Predictors of Plasma Levels of Direct Oral Anticoagulants Among Patients with Atrial Fibrillation in Need of Elective Cardiac Procedures
Predictors of Plasma Levels of Direct Oral Anticoagulants Among Patients with Atrial Fibrillation in Need of Elective Cardiac Procedures
The withdrawal timing of direct oral anticoagulants (DOACs) among patients in need of elective invasive surgery is based o...
A Comprehensive Overview on Chemotherapy-Induced Cardiotoxicity: Insights into the Underlying Inflammatory and Oxidative Mechanisms
A Comprehensive Overview on Chemotherapy-Induced Cardiotoxicity: Insights into the Underlying Inflammatory and Oxidative Mechanisms
While oncotherapy has made rapid progress in recent years, side effects of anti-cancer drugs and treatments have ...
Surgical Treatment for Type A Aortic Dissection after Endovascular Aortic Repair: A 12-year, Single-Center Study
Surgical Treatment for Type A Aortic Dissection after Endovascular Aortic Repair: A 12-year, Single-Center Study
This study aims to investigate the clinical manifestations, operative techniques, and outcomes of patients who undergo ope...
Effectiveness of Vasopressin Against Cardiac Arrest: A Systematic Review of Systematic Reviews
Effectiveness of Vasopressin Against Cardiac Arrest: A Systematic Review of Systematic Reviews
This systematic review (SR) of SRs evaluates the effectiveness of vasopressin alone or in combination with other drugs in ...
The Impacts of Nirmatrelvir–Ritonavir on Myocardial Injury and Long-Term Cardiovascular Outcomes in Hospitalized Patients with COVID-19 amid the Omicron Wave of the Pandemic
The Impacts of Nirmatrelvir–Ritonavir on Myocardial Injury and Long-Term Cardiovascular Outcomes in Hospitalized Patients with COVID-19 amid the Omicron Wave of the Pandemic
Even though nirmatrelvir–ritonavir can improve the short-term morbidity and mortality in COVID-19 patients, the effe...
Evinacumab Reduces Triglyceride-Rich Lipoproteins in Patients with Hyperlipidemia: A Post-Hoc Analysis of Three Randomized Clinical Trials
Evinacumab Reduces Triglyceride-Rich Lipoproteins in Patients with Hyperlipidemia: A Post-Hoc Analysis of Three Randomized Clinical Trials
Natural selection (Mendelian randomization) studies support a causal relationship between elevated triglyceride-rich lipop...
Exercise Improves Heart Function after Myocardial Infarction: The Merits of AMPK
Exercise Improves Heart Function after Myocardial Infarction: The Merits of AMPK
AMPK is considered an important protein signaling pathway that has been shown to exert prominent cardioprotective effects ...
Aloperine Alleviates Myocardial Injury Induced by Myocardial Ischemia and Reperfusion by Activating the ERK1/2/β-catenin Signaling Pathway
Aloperine Alleviates Myocardial Injury Induced by Myocardial Ischemia and Reperfusion by Activating the ERK1/2/β-catenin Signaling Pathway
Myocardial ischemia/reperfusion (I/R) injury can cause severe cardiac damage. Aloperine is a quinolizidine alkaloid found ...
An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity
An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity
Doxorubicin (Dox) is clinically limited due to its dose-dependent cardiotoxicity. Andrographolide (Andro) has been confirm...
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
Sodium glucose linked transporter 2 (SGLT2) inhibition not only reduces morbidity and mortality in patients with diagnosed...
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways
Delayed re-endothelialization after coronary drug-eluting stent implantation is associated with an increased incidence of ...
A Practical Approach to the Management of Residual Cardiovascular Risk: United Arab Emirates Expert Consensus Panel on the Evidence for Icosapent Ethyl and Omega-3 Fatty Acids
A Practical Approach to the Management of Residual Cardiovascular Risk: United Arab Emirates Expert Consensus Panel on the Evidence for Icosapent Ethyl and Omega-3 Fatty Acids
Patients with hyperlipidemia treated with statins remain at a residual cardiovascular (CV) risk. Omega-3 polyunsaturated f...
Isoimperatorin Inhibits Angiogenesis by Suppressing VEGFR2 Signaling Pathway
Isoimperatorin Inhibits Angiogenesis by Suppressing VEGFR2 Signaling Pathway
Angiogenesis involves in many pathological processes, including tumor metastasis, diabetic retinopathy, and rheumatoid art...
Dapagliflozin for Atrial Fibrillation
Dapagliflozin for Atrial Fibrillation
Sodium glucose cotransporter-2 (SGLT2) inhibitors, originally developed for the treat...
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data
Acute kidney injury (AKI) following anticoagulant application has received growing attention as a significant emerging com...
Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network Meta-analysis
Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network Meta-analysis
The available evidence to determine which antidysrhythmic drug is superior for pharmacologic cardioversion of recent-onset...
Changes in Heart Rate Variability Parameters Following Radiofrequency Ablation in Patients with Atrial Fibrillation: A Systematic Review and Meta-Analysis
Changes in Heart Rate Variability Parameters Following Radiofrequency Ablation in Patients with Atrial Fibrillation: A Systematic Review and Meta-Analysis
Radiofrequency (RF) ablation is a prevalent treatment for atrial fibrillation (AF), targeting triggers within the pulmonar...
Hyperkalaemia in Cardiological Patients: New Solutions for an Old Problem
Hyperkalaemia in Cardiological Patients: New Solutions for an Old Problem
Hyperkalaemia is one of the most common electrolyte disorders in patients with cardiovascular disease (CVD). The true burd...
The Function of Circular RNAs in Myocardial Ischemia–Reperfusion Injury: Underlying Mechanisms and Therapeutic Advancement
The Function of Circular RNAs in Myocardial Ischemia–Reperfusion Injury: Underlying Mechanisms and Therapeutic Advancement
Myocardial ischemia reperfusion injury (MIRI) represents a prevalent and severe cardiovascular condition that arises prima...
Instent CTO—What Is the Best Treatment Strategy?
Instent CTO—What Is the Best Treatment Strategy?
Instent chronic total occlusion (IS-CTO) is defined as complete occlusion for at leas...
The Toll-like Receptor-2/4 Antagonist, Sparstolonin B, and Inflammatory Diseases: A Literature Mining and Network Analysis
The Toll-like Receptor-2/4 Antagonist, Sparstolonin B, and Inflammatory Diseases: A Literature Mining and Network Analysis
Sparstolonin B (SsnB) is characterized as a new toll-like receptor (TLR)-2/4 antagonist. However, the effects of SsnB on d...
Comparison Between Drug-Coated Balloon and Stents in Large De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis of RCT Data
Comparison Between Drug-Coated Balloon and Stents in Large De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis of RCT Data
Although a number of studies involving small-vessel de novo coronary disease showed clinical benefits of drug-coated ballo...
Numbers Needed to Treat for Preventing Adverse Cardiovascular Outcomes for Sodium-Glucose Cotransporter 2 Inhibitors vs. Dipeptidyl Peptidase 4 Inhibitors: The Hong Kong Diabetes Study
Numbers Needed to Treat for Preventing Adverse Cardiovascular Outcomes for Sodium-Glucose Cotransporter 2 Inhibitors vs. Dipeptidyl Peptidase 4 Inhibitors: The Hong Kong Diabetes Study
Lee S, Zhou J, Leung KSK, et al. Comparison of sodium-glucose Cotransporter-2 inhibitor and dipeptidyl Peptidase-4 inhibit...
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