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Long-term Dexamethasone Treatment Increases Cardiac Galectin-3 Levels
Long-term Dexamethasone Treatment Increases Cardiac Galectin-3 Levels
Glucocorticoids, which are widely prescribed around the world, cause cardiac remodeling in long-term treatment by triggeri...
Trimetazidine to Reduce Myocardial Fibrosis—Competing Interests with SGLT2 Inhibitors?
Trimetazidine to Reduce Myocardial Fibrosis—Competing Interests with SGLT2 Inhibitors?
Qian G, Xin A, Jiang X, et al. Early trimetazidine therapy in patients undergoing primary percutaneous coronary interventi...
Long Non-coding RNA Involved in the Pathophysiology of Atrial Fibrillation
Long Non-coding RNA Involved in the Pathophysiology of Atrial Fibrillation
Atrial fibrillation (AF) is a prevalent and chronic cardiovascular disorder associated with various pathophysiological alt...
Pulmonary Circulation Under Pressure: Pathophysiological and Therapeutic Implications of BK Channel
Pulmonary Circulation Under Pressure: Pathophysiological and Therapeutic Implications of BK Channel
The large-conductance Ca2+-activated K+ (BK) channel is widely expressed in the pulmonary blood vessels and plays a signif...
Exercise Prevents Glucocorticoid-Induced Myocardial 4-Hydroxynonenal Production
Exercise Prevents Glucocorticoid-Induced Myocardial 4-Hydroxynonenal Production
Long-term administration of glucocorticoids (GCs) increases myocardial oxidative stress. 4-Hydroxynonenal (4-HNE) protein ...
Does Genotype Affect the Efficacy of PCSK9 Inhibitors in the Treatment of Familial Hypercholesterolemia?
Does Genotype Affect the Efficacy of PCSK9 Inhibitors in the Treatment of Familial Hypercholesterolemia?
This review discusses whether patients’ genotype affects the efficacy of PCSK9 inhibitors in treating familial hyper...
High BMI: Another Barrier to Rapid Platelet Inhibition After STEMI PCI
High BMI: Another Barrier to Rapid Platelet Inhibition After STEMI PCI
Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC/AHA/SCAI guideline for coronary artery revascularization: a repo...
Effect of Beta-Blocker on Long-Term Major Cardiovascular Events in High Atherosclerotic Risk Population
Effect of Beta-Blocker on Long-Term Major Cardiovascular Events in High Atherosclerotic Risk Population
Beta-blocker is a frequently used medication in cardiovascular diseases. However, long-term benefit of beta-blocker in pat...
Antiphospholipid Syndrome: State of the Art of Clinical Management
Antiphospholipid Syndrome: State of the Art of Clinical Management
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder clinically characterized by recurrent arterial and venou...
Direct Oral Anticoagulants: Navigating Through Clinical Challenges
Direct Oral Anticoagulants: Navigating Through Clinical Challenges
Direct oral anticoagulants (DOACs) have been approved, for over a decade, by both European and American medicine agencies,...
Treatment and Prophylaxis of Post-pericardiotomy Syndrome in Cardiac Surgery Patients: a Systematic Review
Treatment and Prophylaxis of Post-pericardiotomy Syndrome in Cardiac Surgery Patients: a Systematic Review
Post-pericardiotomy syndrome (PPS) is a common complication of cardiac surgery. This systematic review aimed to investigat...
P2Y12 Inhibitors in STEMI Patients — One Size Does Not Fit All
P2Y12 Inhibitors in STEMI Patients — One Size Does Not Fit All
Ibanez B, James S, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients pre...
Advances in MicroRNA Therapy for Heart Failure: Clinical Trials, Preclinical Studies, and Controversies
Advances in MicroRNA Therapy for Heart Failure: Clinical Trials, Preclinical Studies, and Controversies
Heart failure (HF) is a rapidly growing public health issue with more than 37.7 million patients worldwide and an annual h...
Netrin-1 and RGMa: Novel Regulators of Atherosclerosis-Related Diseases
Netrin-1 and RGMa: Novel Regulators of Atherosclerosis-Related Diseases
Neuronal guidance proteins (NGPs) have been demonstrated to guide the elongation of neuronal axonal grow...
Poking and Prodding So They Take Their Pills
Poking and Prodding So They Take Their Pills
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