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Mitogen-Activated Protein Kinases Mediate Adventitial Fibroblast Activation and Neointima Formation via GATA4/Cyclin D1 Axis
Mitogen-Activated Protein Kinases Mediate Adventitial Fibroblast Activation and Neointima Formation via GATA4/Cyclin D1 Axis
Activation of mitogen-activated protein kinases (MAPKs) by pathological stimuli participates in cardiovascular diseases. D...
The Association of Proton Pump Inhibitors and QT Interval Prolongation in Critically Ill Patients
The Association of Proton Pump Inhibitors and QT Interval Prolongation in Critically Ill Patients
Drug-induced QT interval prolongation has been reported to be related to life-threatening polymorphic ventricular tachycar...
LncRNA Gm15834 Aggravates Cardiac Hypertrophy by Interacting with Sam68 and Activating NF-κB Mediated Inflammation
LncRNA Gm15834 Aggravates Cardiac Hypertrophy by Interacting with Sam68 and Activating NF-κB Mediated Inflammation
Cardiac hypertrophy is the common pathological process of multiple cardiovascular diseases. However, the molecular mechani...
miR-210-5p Promotes Pulmonary Hypertension by Blocking ATP2A2
miR-210-5p Promotes Pulmonary Hypertension by Blocking ATP2A2
Aberrant expression of ATPase sarcoplasmic/endoplasmic retic Ca2+ transporting 2 (ATP2A2) has attracted attention fo...
Impairment of Vascular Homeostasis in Acute Heart Failure: Enter the Monocyte?
Impairment of Vascular Homeostasis in Acute Heart Failure: Enter the Monocyte?
The stimulus for this Editorial Comment was provided by the recent publication in Cardiovascular Drugs and Therapy of an o...
Gab1 Overexpression Attenuates Susceptibility to Ventricular Arrhythmias in Pressure Overloaded Heart Failure Mouse Hearts
Gab1 Overexpression Attenuates Susceptibility to Ventricular Arrhythmias in Pressure Overloaded Heart Failure Mouse Hearts
Grb2 associated binding protein 1 (Gab1) is an adaptor protein that is important for intracellular signal transduction whi...
Machine Learning-Based Model for Predicting Prolonged Mechanical Ventilation in Patients with Congestive Heart Failure
Machine Learning-Based Model for Predicting Prolonged Mechanical Ventilation in Patients with Congestive Heart Failure
Mechanical ventilation (MV) is widely used to relieve respiratory failure in patients with congestive heart failure (CHF)....
Cardiovascular Mechano-Epigenetics: Force-Dependent Regulation of Histone Modifications and Gene Regulation
Cardiovascular Mechano-Epigenetics: Force-Dependent Regulation of Histone Modifications and Gene Regulation
The local mechanical microenvironment impacts on the cell behavior. In the cardiovascular system, cells in both the heart ...
Surgical Treatment for Type A Aortic Dissection after Endovascular Aortic Repair: A 12-year, Single-Center Study
Surgical Treatment for Type A Aortic Dissection after Endovascular Aortic Repair: A 12-year, Single-Center Study
This study aims to investigate the clinical manifestations, operative techniques, and outcomes of patients who undergo ope...
Effectiveness of Vasopressin Against Cardiac Arrest: A Systematic Review of Systematic Reviews
Effectiveness of Vasopressin Against Cardiac Arrest: A Systematic Review of Systematic Reviews
This systematic review (SR) of SRs evaluates the effectiveness of vasopressin alone or in combination with other drugs in ...
Exercise Improves Heart Function after Myocardial Infarction: The Merits of AMPK
Exercise Improves Heart Function after Myocardial Infarction: The Merits of AMPK
AMPK is considered an important protein signaling pathway that has been shown to exert prominent cardioprotective effects ...
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
Sodium glucose linked transporter 2 (SGLT2) inhibition not only reduces morbidity and mortality in patients with diagnosed...
Isoimperatorin Inhibits Angiogenesis by Suppressing VEGFR2 Signaling Pathway
Isoimperatorin Inhibits Angiogenesis by Suppressing VEGFR2 Signaling Pathway
Angiogenesis involves in many pathological processes, including tumor metastasis, diabetic retinopathy, and rheumatoid art...
Dapagliflozin for Atrial Fibrillation
Dapagliflozin for Atrial Fibrillation
Sodium glucose cotransporter-2 (SGLT2) inhibitors, originally developed for the treat...
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data
Acute kidney injury (AKI) following anticoagulant application has received growing attention as a significant emerging com...
Hyperkalaemia in Cardiological Patients: New Solutions for an Old Problem
Hyperkalaemia in Cardiological Patients: New Solutions for an Old Problem
Hyperkalaemia is one of the most common electrolyte disorders in patients with cardiovascular disease (CVD). The true burd...