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IGFBP-3 promotes cachexia-associated lipid loss by suppressing insulin-like growth factor/insulin signaling
IGFBP-3 promotes cachexia-associated lipid loss by suppressing insulin-like growth factor/insulin signaling
Background: Progressive lipid loss of adipose tissue is a major feature of cancer-associated cach
Low diastolic blood pressure and adverse outcomes in inpatients with acute exacerbation of chronic obstructive pulmonary disease: A multicenter cohort study
Low diastolic blood pressure and adverse outcomes in inpatients with acute exacerbation of chronic obstructive pulmonary disease: A multicenter cohort study
Background: Although intensively studied in patients with cardiovascular diseases (CVDs), the pro
Maternal circulating biomarkers associated with placenta accreta spectrum disorders
Maternal circulating biomarkers associated with placenta accreta spectrum disorders
To the Editor: Placenta accreta spectrum (PAS) disorders refer to a spectrum of abnormal placentation. PAS subtypes includ...
Nuclear factor-Y mediates pancreatic β-cell compensation by repressing reactive oxygen species-induced apoptosis under metabolic stress
Nuclear factor-Y mediates pancreatic β-cell compensation by repressing reactive oxygen species-induced apoptosis under metabolic stress
Background: Pancreatic β-cells elevate insulin production and secretion through a compensatory me
Proteome and genome integration analysis of obesity
Proteome and genome integration analysis of obesity
The prevalence of obesity has increased worldwide in recent decades. Genetic factors are now known t
Ferroptosis in acute leukemia
Ferroptosis in acute leukemia
Ferroptosis is an iron-dependent cell death pathway that is different from apoptosis, pyroptosis, an
Bismuth, esomeprazole, metronidazole, and minocycline or tetracycline as a first-line regimen for Helicobacter pylori eradication: A randomized controlled trial
Bismuth, esomeprazole, metronidazole, and minocycline or tetracycline as a first-line regimen for Helicobacter pylori eradication: A randomized controlled trial
Background: Given the general unavailability, common adverse effects, and complicated administrat
Radiotherapy delivery error detection with electronic portal imaging device (EPID)-based in vivo dosimetry
Radiotherapy delivery error detection with electronic portal imaging device (EPID)-based in vivo dosimetry
To the Editor: Due to the highly complex nature of intensity-modulated radiotherapy (IMRT) planning and delivery, patient ...
Effect of complete percutaneous revascularization on improving long-term outcomes of patients with chronic total occlusion and multi-vessel disease
Effect of complete percutaneous revascularization on improving long-term outcomes of patients with chronic total occlusion and multi-vessel disease
Background: Limited data are available on the comparison of clinical outcomes of complete vs. inc
Sodium-glucose cotransporter 2 inhibitors in Asian patients with heart failure
Sodium-glucose cotransporter 2 inhibitors in Asian patients with heart failure
To the Editor: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are recognized as one of the essential drugs for the tre...
Clinical effect of magnetic compression anastomosis on ureterostenosis after kidney transplantation
Clinical effect of magnetic compression anastomosis on ureterostenosis after kidney transplantation
To the Editor: Ureterostenosis is one of the most common complications after kidney transplantation, with an incidence rat...
Microbial and epidemiological factors in early detection of esophageal squamous cell carcinoma and precancerous lesions
Microbial and epidemiological factors in early detection of esophageal squamous cell carcinoma and precancerous lesions
To the Editor: Esophageal cancer (EC) ranks ninth and fifth among the leading cause of global cancer-related morbidity and...
Polygenic score: An anchor holding the whole life course
Polygenic score: An anchor holding the whole life course
In 2001, the draft sequence of the first human genome was reported, followed by a near-complete sequence published in 2004...
Eosinophilic gastroenteritis: Pathogenesis, diagnosis, and treatment
Eosinophilic gastroenteritis: Pathogenesis, diagnosis, and treatment
Eosinophilic gastroenteritis (EGE) is a gastrointestinal disorder of unclear etiology that is charac
Outcome measures of phase III anticancer drug trials in China
Outcome measures of phase III anticancer drug trials in China
To the Editor: Phase III clinical trials have been used to provide evidence in support of the approval of most new agents ...
Changes in the pathogen spectrum of hospitalized adults with community-acquired pneumonia in Fujian Province: A multicenter, retrospective study from 2012 to 2018
Changes in the pathogen spectrum of hospitalized adults with community-acquired pneumonia in Fujian Province: A multicenter, retrospective study from 2012 to 2018
To the Editor: Community-acquired pneumonia (CAP) in adults refers to inflammation of the lung parenchyma involving the al...
Cost-effectiveness evaluation of rapid initiation of antiretroviral therapy based on decision-tree Markov model
Cost-effectiveness evaluation of rapid initiation of antiretroviral therapy based on decision-tree Markov model
To the Editor: Human immunodeficiency virus (HIV) type 1 infection remains a serious and intractable public health problem...
Machine and deep learning-based clinical characteristics and laboratory markers for the prediction of sarcopenia
Machine and deep learning-based clinical characteristics and laboratory markers for the prediction of sarcopenia
Background: Sarcopenia is an age-related progressive skeletal muscle disorder involving the loss
Enthesitis in patients with psoriatic arthritis: A nationwide data from the Chinese Registry of Psoriatic Arthritis (CREPAR)
Enthesitis in patients with psoriatic arthritis: A nationwide data from the Chinese Registry of Psoriatic Arthritis (CREPAR)
Background: The clinical features of enthesitis in patients with psoriatic arthritis (PsA) have b
Corrigendum: Fecal transplantation can alleviate tic severity in a Tourette syndrome mouse model by modulating intestinal flora and promoting serotonin secretion
Corrigendum: Fecal transplantation can alleviate tic severity in a Tourette syndrome mouse model by modulating intestinal flora and promoting serotonin secretion
The authors declare that in the article “Fecal transplantation can alleviate tic severity in a Tourette syndrome mouse mod...
Downregulation of microRNA-23a confers protection against myocardial ischemia/reperfusion injury by upregulating tissue factor pathway inhibitor 2 following luteolin pretreatment in rats
Downregulation of microRNA-23a confers protection against myocardial ischemia/reperfusion injury by upregulating tissue factor pathway inhibitor 2 following luteolin pretreatment in rats
To the Editor: Myocardial ischemia/reperfusion injury (MI/RI) often causes death, dysfunction, or damage to the cardiomyoc...
Relationship between depression and lifestyle factors in Chinese adults using multi-level generalized estimation equation model
Relationship between depression and lifestyle factors in Chinese adults using multi-level generalized estimation equation model
To the Editor: In China, depression is a common mental illness with a lifetime prevalence of 6.8% and a 12-month prevalenc...
Use of antenatal corticosteroids among infants with gestational age at 24 to 31 weeks in 57 neonatal intensive care units of China: a cross-sectional study
Use of antenatal corticosteroids among infants with gestational age at 24 to 31 weeks in 57 neonatal intensive care units of China: a cross-sectional study
Background: Antenatal corticosteroids (ACS) can significantly improve the outcomes of preterm inf
Rapid identification of chronic kidney disease in electronic health record database using computable phenotype combining a common data model
Rapid identification of chronic kidney disease in electronic health record database using computable phenotype combining a common data model
To the Editor: Chronic kidney disease (CKD) is a global burden of the public health. The global prevalence of CKD exceeded...
Roles of alternative splicing in infectious diseases: from hosts, pathogens to their interactions
Roles of alternative splicing in infectious diseases: from hosts, pathogens to their interactions
Alternative splicing (AS) is an evolutionarily conserved mechanism that removes introns and ligates
Genetic background of idiopathic neurodevelopmental delay patients with significant brain deviation volume
Genetic background of idiopathic neurodevelopmental delay patients with significant brain deviation volume
Background: Significant brain volume deviation is an essential phenotype in children with neurode
Impacts of transmembrane serine protease 4 expression on susceptibility to severe acute respiratory syndrome coronavirus 2
Impacts of transmembrane serine protease 4 expression on susceptibility to severe acute respiratory syndrome coronavirus 2
To the Editor: Transmembrane serine protease 4 (TMPRSS4; OMIM: 606565), which encodes a member of the serine protease fami...
Current applications for magnetic resonance-guided focused ultrasound in the treatment of Parkinson's disease
Current applications for magnetic resonance-guided focused ultrasound in the treatment of Parkinson's disease
Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel and minimally invasive technology.
Twice-daily injections and multiple daily injections of insulin in toddlers with type 1 diabetes: a retrospective cohort study
Twice-daily injections and multiple daily injections of insulin in toddlers with type 1 diabetes: a retrospective cohort study
To the Editor: Incidence of type 1 diabetes (T1D) in young children has been increasing over time in China.[1] There are c...
Neoadjuvant ceritinib treatment achieved pathological complete response in patients with anaplastic lymphoma kinase positive stage IIIA-N2 non-small cell lung cancer
Neoadjuvant ceritinib treatment achieved pathological complete response in patients with anaplastic lymphoma kinase positive stage IIIA-N2 non-small cell lung cancer
To the Editor: Anaplastic lymphoma kinase (ALK) fusion oncogene occurs in 3% to 7% of patients with non-small cell lung ca...
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