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Association of cardiopulmonary bypass with acute kidney injury in patients undergoing coronary artery bypass grafting: a retrospective cohort study
Association of cardiopulmonary bypass with acute kidney injury in patients undergoing coronary artery bypass grafting: a retrospective cohort study
To the Editor: Acute kidney injury (AKI) is a frequent complication of both cardiac and major non-cardiac surgeries. Cardi...
Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus
Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus
Background: Type 2 diabetes mellitus (T2DM) is an independent risk factor for colorectal cancer (
Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty
Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty
To the Editor: Introduction of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) has been highly eff...
Jak inhibitors in vitiligo: a meta analysis
Jak inhibitors in vitiligo: a meta analysis
To the Editor: Vitiligo is an autoimmune disease characterized by depigmented patches of skin and is challenging to manage...
Clinical characteristics and risk factors for new-onset cervicogenic headache following elective craniotomy
Clinical characteristics and risk factors for new-onset cervicogenic headache following elective craniotomy
To the Editor: New-onset headache within a week after craniotomy is commonly recognized as acute post-craniotomy headache ...
Updates in psoriasis diagnosis and treatment status in China: results from the National Psoriasis Center Registry
Updates in psoriasis diagnosis and treatment status in China: results from the National Psoriasis Center Registry
To the Editor: Psoriasis is a common chronic immune-mediated systemic inflammatory disease[1] characterized by irritating ...
Systemic lupus erythematosus with diffuse alveolar hemorrhage
Systemic lupus erythematosus with diffuse alveolar hemorrhage
To the Editor: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of various auto...
Increased human neutrophil lipocalin and its clinical relevance in adult-onset Still's disease
Increased human neutrophil lipocalin and its clinical relevance in adult-onset Still's disease
Background: Human neutrophil lipocalin (HNL) has been used extensively to differentiate acute bac
Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial
Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial
Background: Red-cell transfusion is critical for surgery during the peri-operative period; howeve
Burden of multiple myeloma in China: an analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019
Burden of multiple myeloma in China: an analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019
Background: There is limited data to comprehensively evaluate the epidemiological characteristics
Menstrual irregularity, pregnancy outcomes, and birth outcomes in patients with systemic lupus erythematosus of childbearing age in China: a multicenter cross-sectional study
Menstrual irregularity, pregnancy outcomes, and birth outcomes in patients with systemic lupus erythematosus of childbearing age in China: a multicenter cross-sectional study
To the Editor: Systemic lupus erythematosus (SLE) is an autoimmune disease that tends to affect females of childbearing ag...
Does the homologous booster with the inactivated coronavirus disease 2019 vaccine work for the omicron variant? Real-world evidence from Jilin, China
Does the homologous booster with the inactivated coronavirus disease 2019 vaccine work for the omicron variant? Real-world evidence from Jilin, China
1Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610000, China ...
Epidermal growth factor receptor compound and concomitant mutations: advances in precision treatment strategies
Epidermal growth factor receptor compound and concomitant mutations: advances in precision treatment strategies
Epidermal growth factor receptor (EGFR) mutations are common oncogenic driver mutations in patients
Effects of radiation therapy on tumor microenvironment: an updated review
Effects of radiation therapy on tumor microenvironment: an updated review
Cancer is a major threat to human health and causes death worldwide. Research on the role of radioth
Tumor immune microenvironment-modulated nanostrategy for the treatment of lung cancer metastasis
Tumor immune microenvironment-modulated nanostrategy for the treatment of lung cancer metastasis
As one of the most malignant tumors worldwide, lung cancer, fueled by metastasis, has shown rising m
Clinical characteristics of hypersensitivity pneumonitis: non-fibrotic and fibrotic subtypes
Clinical characteristics of hypersensitivity pneumonitis: non-fibrotic and fibrotic subtypes
Background: The presence of fibrosis is a criterion for subtype classification in the newly updat
Shared and distinct abnormalities of brain magnetization transfer ratio in schizophrenia and major depressive disorder: a comparative voxel-based meta-analysis
Shared and distinct abnormalities of brain magnetization transfer ratio in schizophrenia and major depressive disorder: a comparative voxel-based meta-analysis
Background: Patients with schizophrenia (SCZ) and major depressive disorder (MDD) share significa
Opportunities and challenges of digital twin technology in healthcare
Opportunities and challenges of digital twin technology in healthcare
To the Editor: The classic case considered to be the primary application of the digital twin approach is the Apollo 13 mis...
Regulatory T cells and cardiovascular diseases
Regulatory T cells and cardiovascular diseases
Inflammation is a major underlying mechanism in the progression of numerous cardiovascular diseases
Expert consensus on the vitrification of human oocytes and embryos
Expert consensus on the vitrification of human oocytes and embryos
Introduction The cryopreservation of human oocytes and embryos is a key factor in assisted reproductive technol...
Pharmacogenetics and pharmacogenomics in glaucoma therapeutics: the way to personalized therapy
Pharmacogenetics and pharmacogenomics in glaucoma therapeutics: the way to personalized therapy
Glaucoma is a leading cause of irreversible optic nerve damage, with a significant proportion of patients (approximately 1...
Viral load kinetics of the severe acute respiratory syndrome coronavirus 2 Omicron variant in children aged 0 to 3 years and their parents
Viral load kinetics of the severe acute respiratory syndrome coronavirus 2 Omicron variant in children aged 0 to 3 years and their parents
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first confirmed in November 2021 i...
Identification and functional characterization of a novel truncating splicing variant in COL4A5 gene causing X-linked Alport syndrome with astigmatism
Identification and functional characterization of a novel truncating splicing variant in COL4A5 gene causing X-linked Alport syndrome with astigmatism
To the Editor: Alport syndrome (AS) is a rare hereditary progressive nephropathy manifested with hematuria, proteinuria, g...
Integrative pan-cancer analysis of cuproplasia-associated genes for the genomic and clinical characterization of 33 tumors
Integrative pan-cancer analysis of cuproplasia-associated genes for the genomic and clinical characterization of 33 tumors
Background: The molecular mechanisms driving tumorigenesis have continually been the focus of res
Trans-ethnic Mendelian randomization study of systemic lupus erythematosus and common female hormone-dependent malignancies
Trans-ethnic Mendelian randomization study of systemic lupus erythematosus and common female hormone-dependent malignancies
Background: Observational research has reported that systemic lupus erythematosus (SLE) is relate
Familial aggregation of esophageal cancer
Familial aggregation of esophageal cancer
Esophageal cancer has a substantial health burden in China, especially in the northern regions. Although family history ha...
Development and validation of an m6A RNA methylation regulator-based signature for the prediction of prognosis and immunotherapy in cutaneous melanoma
Development and validation of an m6A RNA methylation regulator-based signature for the prediction of prognosis and immunotherapy in cutaneous melanoma
To the Editor: The incidence of cutaneous melanoma, which has an extremely poor prognosis and is responsible for the major...
SHED-derived exosomes ameliorate hyposalivation caused by Sjögren's syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression
SHED-derived exosomes ameliorate hyposalivation caused by Sjögren's syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression
Background: Sjögren's syndrome (SS) is an autoimmune disorder characterized by sicca syndrome and
Role of steroid receptor-associated and regulated protein in tumor progression and progesterone receptor signaling in endometrial cancer
Role of steroid receptor-associated and regulated protein in tumor progression and progesterone receptor signaling in endometrial cancer
Background: Steroid receptor-associated and regulated protein (SRARP) suppresses tumor progressio
Front-line therapy for brain metastases and non-brain metastases in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: a network meta-analysis
Front-line therapy for brain metastases and non-brain metastases in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: a network meta-analysis
Background: The brain is a common metastatic site in patients with non-small cell lung cancer (NS
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