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Delineation of biliary epithelial cell dynamics in maternal liver during pregnancy
Delineation of biliary epithelial cell dynamics in maternal liver during pregnancy
Abstract In pregnant mice, the maternal liver expands drastically during gestation, which is believed to be essential to a...
Biochemical propensity mapping for structural and functional anatomy of importin α IBB domain
Biochemical propensity mapping for structural and functional anatomy of importin α IBB domain
Abstract Importin α has been described as a nuclear protein transport receptor that enables proteins synthesized in ...
Growth and division mode plasticity is dependent on cell density in marine‐derived black yeasts
Growth and division mode plasticity is dependent on cell density in marine‐derived black yeasts
Abstract The diversity and ecological contribution of the fungus kingdom in the marine environment remain under-studied. A...
Egg components reverse the atrophy induced by injury in skeletal muscles
Egg components reverse the atrophy induced by injury in skeletal muscles
Abstract Skeletal muscle atrophy is the loss of muscle tissue caused by factors such as inactivity, malnutrition, aging, a...
Systemic innate immune response induces death of olfactory receptor neurons in Drosophila
Systemic innate immune response induces death of olfactory receptor neurons in Drosophila
Abstract Neural functions are known to decline during normal aging and neurodegenerative diseases. However, the mechanisms...
Sima, a Drosophila homolog of HIF‐1α, in fat body tissue inhibits larval body growth by inducing Tribbles gene expression
Sima, a Drosophila homolog of HIF‐1α, in fat body tissue inhibits larval body growth by inducing Tribbles gene expression
Abstract Limited oxygen availability impairs normal body growth, although the underlying mechanisms are not fully understo...
Glucolipids and lipoteichoic acids affect the activity of SigI, an alternative sigma factor, and WalKR, an essential two‐component system, in Bacillus subtilis.
Glucolipids and lipoteichoic acids affect the activity of SigI, an alternative sigma factor, and WalKR, an essential two‐component system, in Bacillus subtilis.
Abstract In a Bacillus subtilis ugtP mutant lacking glucolipids, SigI was activated in the log phase, and the activation o...
Histone variant H2A.Z plays multiple roles in the maintenance of heterochromatin integrity
Histone variant H2A.Z plays multiple roles in the maintenance of heterochromatin integrity
Abstract H2A.Z, an evolutionally well conserved histone H2A variant, is involved in many biological processes. Although th...
Volume Index
Volume Index
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Identification and characterization of novel proteins associated with CHD4
Identification and characterization of novel proteins associated with CHD4
Abstract The CHD (chromodomain helicase DNA binding protein) family consists of nine chromatin remodeling factors that alt...
The cell type‐specific ER membrane protein UGS148 is not essential in mice
The cell type‐specific ER membrane protein UGS148 is not essential in mice
Abstract Genomes of higher eukaryotes encode many uncharacterized proteins, and the functions of these proteins cannot be ...
LincRNA‐p21 exon 1 expression correlates with Cdkn1a expression in vivo
LincRNA‐p21 exon 1 expression correlates with Cdkn1a expression in vivo
Abstract LincRNA-p21 is a long intergenic non-coding RNA (LincRNA) gene reported to activate the transcription of the adja...
Glioma cells remotely promote erythropoiesis as a self‐expanding strategy of cancer stem cells
Glioma cells remotely promote erythropoiesis as a self‐expanding strategy of cancer stem cells
Abstract Cancer stem cells are a promising target for cancer eradication due to their responsibility for therapy-resistanc...
LincRNA‐p21 exon1 expression correlates with Cdkn1a expression in vivo
LincRNA‐p21 exon1 expression correlates with Cdkn1a expression in vivo
Abstract LincRNA-p21 is a long intergenic non-coding RNA (LincRNA) gene reported to activate the transcription of the adja...
Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF‐κB signaling
Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF‐κB signaling
Abstract RASSF6 is a member of the tumor suppressor Ras association domain family (RASSF) proteins. We have reported using...
Effect of volatile fatty acids on adipocyte differentiation in bovine dedifferentiated fat (DFAT) cells in vitro
Effect of volatile fatty acids on adipocyte differentiation in bovine dedifferentiated fat (DFAT) cells in vitro
Abstract Here, we established dedifferentiated fat (DFAT) cells from mature bovine adipocytes and then examined the effect...
Generating a New Mouse Model for Nuclear PTEN Deficiency by a Single K13R Mutation
Generating a New Mouse Model for Nuclear PTEN Deficiency by a Single K13R Mutation
Abstract Many human diseases, including cancer and neurological abnormalities, are linked to deficiencies of PTEN, a dual ...
Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice reveals the implication of Rassf6 in the regulation of NF‐κB signaling
Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice reveals the implication of Rassf6 in the regulation of NF‐κB signaling
Abstract RASSF6 is a member of the tumor suppressor Ras-association domain family (RASSF) proteins. We have reported using...
Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons
Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons
Abstract Van Gogh-like 2 (Vangl2) is a mammalian homolog of Drosophila core planar cell polarity (PCP) protein Vang/Strabi...
Replacement of owl monkey centromere satellite by a newly evolved variant was a recent and rapid process
Replacement of owl monkey centromere satellite by a newly evolved variant was a recent and rapid process
Abstract Alpha satellite DNA is a major DNA component of primate centromeres. We previously reported that Azara's owl monk...
Identification of ksg1 mutation showing long‐lived phenotype in fission yeast
Identification of ksg1 mutation showing long‐lived phenotype in fission yeast
Abstract Fission yeast is a good model organism for the study of lifespan. To elucidate the mechanism, we screened for lon...
Importin α2 association with chromatin: Direct DNA binding via a novel DNA‐binding domain
Importin α2 association with chromatin: Direct DNA binding via a novel DNA‐binding domain
Abstract The nuclear transport of proteins is important for facilitating appropriate nuclear functions. The importin ;...
ZomB is essential for chemotaxis of Vibrio alginolyticus by the rotational direction control of the polar flagellar motor
ZomB is essential for chemotaxis of Vibrio alginolyticus by the rotational direction control of the polar flagellar motor
Abstract Bacteria exhibit chemotaxis by controlling flagellar rotation to move toward preferred places or away from non-pr...
Production of therapeutic iduronate‐2‐sulfatase enzyme with a novel single‐stranded RNA virus vector
Production of therapeutic iduronate‐2‐sulfatase enzyme with a novel single‐stranded RNA virus vector
Abstract The Sendai virus vector has received a lot of attention due to its broad tropism for mammalian cells. As a result...
Visualizing looping of two endogenous genomic loci using synthetic zinc‐finger proteins with anti‐FLAG and anti‐HA frankenbodies in living cells
Visualizing looping of two endogenous genomic loci using synthetic zinc‐finger proteins with anti‐FLAG and anti‐HA frankenbodies in living cells
ABSTRACT In eukaryotic nuclei, chromatin loops mediated through cohesin are critical structures that regulate gene express...
Post‐translational modifications of proteins associated with yeast peroxisome membrane: An essential mode of regulatory mechanism
Post‐translational modifications of proteins associated with yeast peroxisome membrane: An essential mode of regulatory mechanism
Abstract Peroxisomes are single membrane-bound organelles important for the optimum functioning of eukaryotic cells. Semin...
Loss of Caenorhabditis elegans homologue of human MOB4 compromises life span, health life span, and thermotolerance
Loss of Caenorhabditis elegans homologue of human MOB4 compromises life span, health life span, and thermotolerance
Abstract Mob1/phocein family proteins are conserved from yeast to mammals. Human has four MOB genes, MOB1, 2, 3, and 4. Hu...
Gene trapping reveals a new transcriptionally active genome element: the chromosome‐specific clustered trap region
Gene trapping reveals a new transcriptionally active genome element: the chromosome‐specific clustered trap region
Abstract Nearly half of the human genome consists of repetitive sequences such as long interspersed nuclear elements. The ...
Mulberry fruit extract alleviates the intracellular amyloid β oligomer‐induced cognitive disturbance and oxidative stress in Alzheimer’s disease model mice
Mulberry fruit extract alleviates the intracellular amyloid β oligomer‐induced cognitive disturbance and oxidative stress in Alzheimer’s disease model mice
Abstract Intracellular amyloid β (Aβ) oligomers are key therapeutic targets because they are strongly cytotoxi...
Protease inhibitory activity of secretory leukocyte protease inhibitor ameliorates murine experimental colitis by protecting the intestinal epithelial barrier
Protease inhibitory activity of secretory leukocyte protease inhibitor ameliorates murine experimental colitis by protecting the intestinal epithelial barrier
Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory disorder in the intestine, and the dysfunction of inte...
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