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Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation
Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation
The continuous exposure of blood to a non-biological surface during extracorporeal membrane oxygenation (ECMO) may lead to...
Quantitative analysis of apparent diffusion coefficients to predict neurological prognosis in cardiac arrest survivors: an observational derivation and internal–external validation study
Quantitative analysis of apparent diffusion coefficients to predict neurological prognosis in cardiac arrest survivors: an observational derivation and internal–external validation study
This study aimed to validate apparent diffusion coefficient (ADC) values and thresholds to predict poor neurological outco...
Traumatic injury characteristics and patient demographics shape the human systemic immune response to injury
Traumatic injury characteristics and patient demographics shape the human systemic immune response to injury
medRxiv - The Preprint Server for Health Sciences
Application of physiological network mapping in the prediction of survival in critically ill patients with acute liver failure
Application of physiological network mapping in the prediction of survival in critically ill patients with acute liver failure
medRxiv - The Preprint Server for Health Sciences
Lower airway microbiota compositions differ between influenza, COVID-19 and bacteria-related acute respiratory distress syndromes
Lower airway microbiota compositions differ between influenza, COVID-19 and bacteria-related acute respiratory distress syndromes
Acute respiratory distress syndrome (ARDS) is responsible for 400,000 deaths annually worldwide. Few improvements have bee...
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
In acute respiratory distress syndrome (ARDS), respiratory drive often differs among patients with similar clinical charac...
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure
In this study, the concentrations of inflammatory cytokines were measured in the bronchial epithelial lining fluid (ELF) a...
Immediate inflammatory response to mechanical circulatory support in a porcine model of severe cardiogenic shock
Immediate inflammatory response to mechanical circulatory support in a porcine model of severe cardiogenic shock
In selected cases of cardiogenic shock, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is combined with tran...
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hy...
Effect of mortality prediction models on resource use benchmarking of intensive care units
Effect of mortality prediction models on resource use benchmarking of intensive care units
The authors had permission from FINDATA (Social and Health Data Permit Authority) to analyse the data. A secondary use of ...
Significance of critical closing pressures (starling resistors) in arterial circulation
Significance of critical closing pressures (starling resistors) in arterial circulation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring mechanical ventilati...
Ineffectiveness of hemoadsorption in large animals with abdominal sepsis: a randomized controlled porcine study
Ineffectiveness of hemoadsorption in large animals with abdominal sepsis: a randomized controlled porcine study
The use of hemoadsorption (HA) has become popular in the treatment of vasoplegic states associated with massive cytokine r...
ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock
ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock
Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blockers (ARB) medications are widely prescribed. ...
Augmenting mortality prediction with medication data and machine learning models
Augmenting mortality prediction with medication data and machine learning models
medRxiv - The Preprint Server for Health Sciences
Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial
Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial
Randomized data evaluating the impact of the extracorporeal cardiopulmonary resuscitation (ECPR) approach on long-term cli...
Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis
Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis
To perform a systematic review with meta-analysis with the dual intent of assessing the impact of attaining aggressive vs....
Contribution of electrical impedance tomography to personalize positive end-expiratory pressure under ECCO2R
Contribution of electrical impedance tomography to personalize positive end-expiratory pressure under ECCO2R
Extracorporeal Carbon Dioxide Removal (ECCO2R) is used in acute respiratory distress syndrome (ARDS) patients to facilitat...
Interfacility transfer of the critically ill: Transfer status does not influence survival
Interfacility transfer of the critically ill: Transfer status does not influence survival
Regionalized healthcare networks with centralized tertiary care centers are common in Canada. Centralizing specialist care...
Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers
Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers
Administration of oxygen therapy is common, yet there is a lack of knowledge on its ability to prevent cellular hypoxia as...
The Effect of Albumin Administration in Critically Ill Patients: A Retrospective Single-Center Analysis
The Effect of Albumin Administration in Critically Ill Patients: A Retrospective Single-Center Analysis
OBJECTIVES: The aim of this study was to analyze the development of albumin administration in pat
Fixed- Versus Variable-Dose Prothrombin Complex Concentrate for the Emergent Reversal of Vitamin K Antagonists: A Systematic Review and Meta-Analysis
Fixed- Versus Variable-Dose Prothrombin Complex Concentrate for the Emergent Reversal of Vitamin K Antagonists: A Systematic Review and Meta-Analysis
OBJECTIVES: Four-factor prothrombin complex concentrate (4-PCC) is recommended for rapid reversal
Comment on “Dexmedetomidine Sedation in Traumatic Brain Injury: A Transforming Clinical Research and Knowledge in Traumatic Brain Injury Study”
Comment on “Dexmedetomidine Sedation in Traumatic Brain Injury: A Transforming Clinical Research and Knowledge in Traumatic Brain Injury Study”
1 Department of Anesthesia and Intensive Care, Jaber Al Ahmad Al Sabah Hospital, Arabian Gulf, Kuwait. 2 Depa...
Hyperchloremia: Cause or Consequence of Acute Kidney Injury?
Hyperchloremia: Cause or Consequence of Acute Kidney Injury?
1 Anesthesiology department, centre hospitalier de Cornouaille, Quimper, France. 2 Anesthesiology Department,...
The Promise and Opportunity Costs of New Rehabilitation Technology in the ICU*
The Promise and Opportunity Costs of New Rehabilitation Technology in the ICU*
ICU survivors are at risk of important disability, which can last up to 8 years post-critical illness (1). The COVID-19 pa...
Evolving Understanding of Patients’ Experiences in Acute Care Trials Without Prospective Consent*
Evolving Understanding of Patients’ Experiences in Acute Care Trials Without Prospective Consent*
Challenges related to informed consent have plagued clinical trials in critical care because patients are acutely ill, stu...
What Exactly Is Recommended for Patient Physical Activity During an ICU Stay?*
What Exactly Is Recommended for Patient Physical Activity During an ICU Stay?*
Movement is life. From birth to death and every moment in between, even when we are asleep, people move, and change positi...
Potentially Injurious Patient-Ventilator Interactions, Challenges Beyond Excess Stress and Strain*
Potentially Injurious Patient-Ventilator Interactions, Challenges Beyond Excess Stress and Strain*
1 Division of Respirology, Department of Medicine, University Health Network and Mount Sinai Hospital, Toronto, ON,...
Near-Infrared Spectroscopy in Pediatric Cardiac Arrest: A Piece of the Clinical Picture*
Near-Infrared Spectroscopy in Pediatric Cardiac Arrest: A Piece of the Clinical Picture*
1 Division of Cardiology, Department of Pediatrics, Lucile Packard Children’s Hospital at Stanford Medical Center, ...
Innovation in Enrichment: Is Persistence Enough?*
Innovation in Enrichment: Is Persistence Enough?*
1 NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, NY. 2 Division of Pulmonary & Critical...
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