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An index of the initial blood pressure response to angiotensin II treatment and its association with clinical outcomes in vasodilatory shock
An index of the initial blood pressure response to angiotensin II treatment and its association with clinical outcomes in vasodilatory shock
No standardized index exists to assess cardiovascular responsiveness to angiotensin-II. We hypothesized that a standardize...
Discarded intravenous medication in the ICU: the GAME-OVER multicenter prospective observational study
Discarded intravenous medication in the ICU: the GAME-OVER multicenter prospective observational study
Medication waste is a contributor to the healthcare environmental footprint and impacts ecosystems. Data on medication was...
The impact of evaluation strategy on sepsis prediction model performance metrics in intensive care data
The impact of evaluation strategy on sepsis prediction model performance metrics in intensive care data
medRxiv - The Preprint Server for Health Sciences
Earlier Detection of Brain Injury Using Optical Brain Pulse Monitoring in Critically Ill Patients Following Cardiac Arrest
Earlier Detection of Brain Injury Using Optical Brain Pulse Monitoring in Critically Ill Patients Following Cardiac Arrest
medRxiv - The Preprint Server for Health Sciences
Comparison of artificial intelligence and logistic regression models for mortality prediction in acute respiratory distress syndrome: a systematic review and meta-analysis
Comparison of artificial intelligence and logistic regression models for mortality prediction in acute respiratory distress syndrome: a systematic review and meta-analysis
The application of artificial intelligence (AI) in predicting the mortality of acute respiratory distress syndrome (ARDS) ...
Early sepsis recognition: a pilot study using a rapid high-multiplex host-response mRNA diagnostic test
Early sepsis recognition: a pilot study using a rapid high-multiplex host-response mRNA diagnostic test
Early sepsis diagnosis is essential to allow timely initiation of adequate care. The TriVerity™ Test, performed on t...
Teicoplanin pharmacokinetics in critically ill patients on extracorporeal organ support: a retrospective analysis
Teicoplanin pharmacokinetics in critically ill patients on extracorporeal organ support: a retrospective analysis
Extracorporeal membrane oxygenation (ECMO) can alter the pharmacokinetics of diverse antimicrobials, posing challenges in ...
Point-of-care regional anesthesia in intensive care units: A multi-center professional practice evaluation
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Limitations of SpO2 / FiO2-ratio for classification and monitoring of acute respiratory distress syndrome—an observational cohort study
Limitations of SpO2 / FiO2-ratio for classification and monitoring of acute respiratory distress syndrome—an observational cohort study
The ratio of pulse-oximetric peripheral oxygen saturation to fraction of inspired oxygen (SpO2/FiO2) has been proposed as ...
The green ICU: how to interpret green? A multiple perspective approach
The green ICU: how to interpret green? A multiple perspective approach
Mitigating environmental impacts is an urgent challenge supported by (scientific) intensive care societies worldwide. Howe...
Peripheral blood mononuclear cell transcriptomic trajectories reveal dynamic regulation of inflammatory actors in delirium
Peripheral blood mononuclear cell transcriptomic trajectories reveal dynamic regulation of inflammatory actors in delirium
medRxiv - The Preprint Server for Health Sciences
Sepsis-induced cardiac dysfunction: mitochondria and energy metabolism
Sepsis-induced cardiac dysfunction: mitochondria and energy metabolism
Sepsis is a life-threatening multi-organ dysfunction syndrome caused by dysregulated host response to infection, posing a ...
Impact of age and mean intracranial pressure on the morphology of intracranial pressure waveform and its association with mortality in traumatic brain injury
Impact of age and mean intracranial pressure on the morphology of intracranial pressure waveform and its association with mortality in traumatic brain injury
Morphological analysis of intracranial pressure (ICP) pulse waveforms provides indirect information on cerebrospinal compl...
Individual mHLA-DR trajectories in the ICU as predictors of early infections following liver transplantation: a prospective observational study
Individual mHLA-DR trajectories in the ICU as predictors of early infections following liver transplantation: a prospective observational study
Infections are a leading cause of early mortality after liver transplantation (LT). Prior to transplantation, cirrhosis-as...
Interaction between clock genes, melatonin and cardiovascular outcomes from ICU patients
Interaction between clock genes, melatonin and cardiovascular outcomes from ICU patients
Circadian rhythms, driven by biological clocks, help organisms align their physiological functions with environmental chan...
Authors reply: “Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis”
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Pediatric Blunt Cervical Spine Trauma – Current State of Evaluation
The evaluation of the pediatric cervical spine (CS) in blunt trauma patients requires special attention and consideration....
Generalization of regional citrate anticoagulation for continuous renal replacement therapy is not associated with an increased rate of severe complications
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Multisystem hemodynamic effects of terlipressin in cirrhosis: A scoping review
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Early high-sensitivity troponin elevation and short-term mortality in sepsis: a systematic review with meta-analysis
Early high-sensitivity troponin elevation and short-term mortality in sepsis: a systematic review with meta-analysis
Serum cardiac troponin (cTn) elevation is a well-established phenomenon in sepsis. However, the clinical significance of t...
Quantification of facial cues for acute illness: a systematic scoping review
Quantification of facial cues for acute illness: a systematic scoping review
The patient’s face provides healthcare professionals with important information about the patient’s general ap...
The effect of therapeutic plasma exchange on the inflammatory response in septic shock: a secondary analysis of the EXCHANGE-1 trial
The effect of therapeutic plasma exchange on the inflammatory response in septic shock: a secondary analysis of the EXCHANGE-1 trial
Sepsis and septic shock, defined by a profound immune dysregulation, are among the leading causes of death in the intensiv...
Impact of Dexmedetomidine on the Prognosis of Patients with Sepsis-Induced Myocardial Injury: A Retrospective Cohort Study
Impact of Dexmedetomidine on the Prognosis of Patients with Sepsis-Induced Myocardial Injury: A Retrospective Cohort Study
medRxiv - The Preprint Server for Health Sciences
Patient–ventilator synchrony under non-invasive ventilation is improved by an automated real time waveform analysis algorithm: a bench study
Patient–ventilator synchrony under non-invasive ventilation is improved by an automated real time waveform analysis algorithm: a bench study
Because of inherent leaks, obtaining good patient–ventilator synchrony during non-invasive ventilation (NIV) is chal...
Letter to the editor: “Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis”
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Sexual dimorphism during LPS-induced systemic inflammation
Sexual dimorphism during LPS-induced systemic inflammation
medRxiv - The Preprint Server for Health Sciences
Comparative evaluation and performance of large language models on expert level critical care questions: a benchmark study
Comparative evaluation and performance of large language models on expert level critical care questions: a benchmark study
Large language models (LLMs) show increasing potential for their use in healthcare for administrative support and clinical...
Pertussis infection in critically ill infants: meta-analysis and validation of a mortality score
Pertussis infection in critically ill infants: meta-analysis and validation of a mortality score
Despite widespread vaccination programs, pertussis continues circulating within populations and remains a life-threatening...
Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel-group, open-label study
Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel-group, open-label study
Nebulised unfractionated heparin may attenuate COVID-19 ARDS by reducing pulmonary microvascular thrombosis, blocking SARS...
Noninvasive multimodal neuromonitoring in patients with post-cardiac arrest brain injury: a survey from China’s intensive care units
Noninvasive multimodal neuromonitoring in patients with post-cardiac arrest brain injury: a survey from China’s intensive care units
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
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