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Bacteremic nosocomial pneumonia caused by Gram-negative bacilli: results from the nationwide ALARICO study in Italy
Bacteremic nosocomial pneumonia caused by Gram-negative bacilli: results from the nationwide ALARICO study in Italy
To describe the clinical characteristics and outcomes of patients with nosocomial pneumonia (NP) caused by carbap...
Anidulafungin exposure and population pharmacokinetics in critically ill patients with invasive candidiasis
Anidulafungin exposure and population pharmacokinetics in critically ill patients with invasive candidiasis
Anidulafungin is recommended as a first-line treatment for invasive Candida infections in critically ill patients. Pharmac...
Detection of Streptococcus pyogenes in an atypical hematological diagnostic case
Detection of Streptococcus pyogenes in an atypical hematological diagnostic case
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Embolic complications in a large contemporary cohort of infective endocarditis: do we need score model?
Embolic complications in a large contemporary cohort of infective endocarditis: do we need score model?
Infective endocarditis (IE) is a heterogeneous disease undergoing epidemiological changes. Whether those changes have an i...
Piperacillin/tazobactam vs. cefepime or carbapenems for the treatment of bloodstream infections due to bacteria producing chromosomal AmpC beta-lactamase: a systematic review and meta-analysis
Piperacillin/tazobactam vs. cefepime or carbapenems for the treatment of bloodstream infections due to bacteria producing chromosomal AmpC beta-lactamase: a systematic review and meta-analysis
The best treatment for bloodstream infections (BSI) due to chromosomal AmpC (c-AmpC) producing Enterobacterales is not cle...
Syncopes, paresis and loss of vision after COVID-19 mRNA-based vaccination and SARS-CoV-2 infection
Syncopes, paresis and loss of vision after COVID-19 mRNA-based vaccination and SARS-CoV-2 infection
mRNA-based vaccines played a key role in fighting the global COVID-19 pandemic by saving millions of lives. In rare cases,...
The role of vitamin D in the prevention and treatment of tuberculosis: a meta-analysis of randomized controlled trials
The role of vitamin D in the prevention and treatment of tuberculosis: a meta-analysis of randomized controlled trials
To explore the role of supplementing vitamin D in the prevention and treatment of tuberculosis infection through a meta-an...
Gram-negative bloodstream infections in six German university hospitals, 2016–2020: clinical and microbiological features
Gram-negative bloodstream infections in six German university hospitals, 2016–2020: clinical and microbiological features
To analyze the longitudinal epidemiology and antimicrobial resistance (AMR) patterns of Gram-negative bloodstream infectio...
Importance of the neutrophil-to-lymphocyte ratio as a marker for microbiological specimens in critically ill patients after liver or lung transplantation
Importance of the neutrophil-to-lymphocyte ratio as a marker for microbiological specimens in critically ill patients after liver or lung transplantation
The correct and early diagnosis of an infection is pivotal for patients, especially if the patients are immunocompromised....
Shorter vs. standard-duration antibiotic therapy for nocardiosis: a multi-center retrospective cohort study
Shorter vs. standard-duration antibiotic therapy for nocardiosis: a multi-center retrospective cohort study
The prolonged treatment recommended for nocardiosis does not rely on strong evidence. Consequently, some clinicians opt sh...
Prophylactic vs preemptive strategy for the prevention of CMV disease in solid organ transplant recipients: systematic review and meta-analysis of randomized controlled trials
Prophylactic vs preemptive strategy for the prevention of CMV disease in solid organ transplant recipients: systematic review and meta-analysis of randomized controlled trials
Cytomegalovirus (CMV) is associated with significant morbidity and mortality among solid organ transplant (SOT) recipients...
SeptAsTERS- SeptiCyte® RAPID as assessment tool for early recognition of sepsis – a prospective observational study
SeptAsTERS- SeptiCyte® RAPID as assessment tool for early recognition of sepsis – a prospective observational study
Early recognition of sepsis is critical to patient outcome, with mortality increasing with every hour of delay in treatmen...
Pre-hospital time delays in imported malaria diagnosis in hospitalized sub-Saharan travelers and migrants: not only on the patient’s shoulders
Pre-hospital time delays in imported malaria diagnosis in hospitalized sub-Saharan travelers and migrants: not only on the patient’s shoulders
To analyze the diagnostic delay in malaria related to misdiagnosis at first medical visit and its association with the ris...
In vitro activity of ceftazidime-avibactam/aztreonam combination against MBL-producing Pseudomonas aeruginosa strains
In vitro activity of ceftazidime-avibactam/aztreonam combination against MBL-producing Pseudomonas aeruginosa strains
The emergence of multidrug-resistant P. aeruginosa isolates poses a challenge to healthcare systems worldwide. Rising numb...
Post-COVID recovery is faster after an infection with the SARS-CoV-2 Omicron variant: a population-based cohort study
Post-COVID recovery is faster after an infection with the SARS-CoV-2 Omicron variant: a population-based cohort study
Post-COVID-19 condition (PCC) poses a substantial burden to affected individuals, health care systems, and society as a wh...
Rare and risky: a unique case of concurrent chronic pulmonary aspergillosis and lemierre syndrome
Rare and risky: a unique case of concurrent chronic pulmonary aspergillosis and lemierre syndrome
Lemierre Syndrome is a condition that appears to have been overlooked in recent decades in clinical practice, often result...
Burden of post–acute COVID-19 sequelae in healthcare workers and its course over a 30-month period–results from a prospective multicentre cohort
Burden of post–acute COVID-19 sequelae in healthcare workers and its course over a 30-month period–results from a prospective multicentre cohort
As healthcare workers (HCW) have been disproportionally affected by COVID-19, its post-acute sequelae (PASC) in HCW can im...
LTT-Validity in diagnosis and therapeutical decision making of neuroborreliosis: a prospective dual-centre study
LTT-Validity in diagnosis and therapeutical decision making of neuroborreliosis: a prospective dual-centre study
The key objective of this study was to assess the validity of a commercially available in-house Lymphocyte Transformation ...
Infants < 90 days of age with late-onset sepsis display disturbances of the microbiome-immunity interplay
Infants < 90 days of age with late-onset sepsis display disturbances of the microbiome-immunity interplay
We hypothesized that previously healthy infants &lt; 90 days of age with late-onset sepsis (LOS) have dist...
Real-life data of hepatitis C treatment with direct acting antiviral therapy in persons injecting drugs or on opioid substitution therapy
Real-life data of hepatitis C treatment with direct acting antiviral therapy in persons injecting drugs or on opioid substitution therapy
HCV treatment has been revolutionized by introduction of direct-acting antiviral therapy (DAA). Short treatment duration o...
PaedVacCOVID - safety of the BNT162b2 vaccine against the SARS-CoV-2 in children with and without comorbidities aged 5 to 11 years
PaedVacCOVID - safety of the BNT162b2 vaccine against the SARS-CoV-2 in children with and without comorbidities aged 5 to 11 years
Little is known about specific safety aspects in children with significant comorbidities receiving the mRNA vaccine BNT162...
Sex-dependent variability of isoniazid and rifampicin serum levels in patients with tuberculosis
Sex-dependent variability of isoniazid and rifampicin serum levels in patients with tuberculosis
Drug-sensitive TB (DS-TB) is treated with isoniazid, rifampicin, ethambutol, and pyrazinamide. Factors like fast-metaboliz...
In vivo divergent evolution of cross-resistance to new β-lactam/β-lactamase inhibitor combinations in Pseudomonas aeruginosa following ceftazidime/avibactam treatment
In vivo divergent evolution of cross-resistance to new β-lactam/β-lactamase inhibitor combinations in Pseudomonas aeruginosa following ceftazidime/avibactam treatment
To describe and characterize the evolutionary process of cross-resistance to ceftazidime/avibactam, ceftolozane/tazobactam...
The cGAS-STING pathway in HIV-1 and Mycobacterium tuberculosis coinfection
The cGAS-STING pathway in HIV-1 and Mycobacterium tuberculosis coinfection
Mycobacterium tuberculosis (M. tuberculosis) infection is the most common opportunistic infection in human immunodeficienc...
Clinical features and immune memory of breakthrough infection in children after age-appropriate 13-valent pneumococcal conjugate vaccination in Taiwan
Clinical features and immune memory of breakthrough infection in children after age-appropriate 13-valent pneumococcal conjugate vaccination in Taiwan
As certain vaccine serotypes are still circulating within the community during the PCV13 era, we aimed to delineate the cl...
Characterising HIV-Indicator conditions among two nationwide long-term cohorts of people living with HIV in Germany (1999–2023)
Characterising HIV-Indicator conditions among two nationwide long-term cohorts of people living with HIV in Germany (1999–2023)
Information about occurrence and affected groups of symptoms/diagnoses indicative of an HIV infection (so-called HIV indic...
Characterizing CRP dynamics during acute infections
Characterizing CRP dynamics during acute infections
C-reactive protein (CRP) is a common proxy of inflammation, but accurate characterizations of its dynamics during acute in...
Discrepancy between antibiotic pack sizes and guideline recommendations: a real-world analysis based on claims data
Discrepancy between antibiotic pack sizes and guideline recommendations: a real-world analysis based on claims data
Antibiotics are often only available in predefined pack sizes, which may not align with guideline recommendations. This ca...
Association between adjunctive rifampin and gentamicin use and outcomes for patients with staphylococcal prosthetic valve endocarditis: a propensity-score adjusted retrospective cohort study
Association between adjunctive rifampin and gentamicin use and outcomes for patients with staphylococcal prosthetic valve endocarditis: a propensity-score adjusted retrospective cohort study
Although guidelines recommend adjunctive rifampin and gentamicin use for patients with staphylococcal prosthetic valve end...
Correction: Results of a monocentric field study: value of histology compared to sonication method and conventional tissue culture in the diagnosis of periprosthetic joint infection (PJI)
Correction: Results of a monocentric field study: value of histology compared to sonication method and conventional tissue culture in the diagnosis of periprosthetic joint infection (PJI)
Authors and AffiliationsDepartment of Trauma Surgery, Orthopaedics & Sports Medicine, Hospital of Brothers of Mercy, R...
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