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Triiodothyronine Augmentation for Treatment-Resistant Depression
A middle-aged woman with treatment-resistant depression and atypical features, who had failed several therapeutic trials, ...
Importance of Screening for Irritability When Assessing for Geriatric Depression
The objective of this study was to determine the frequency of irritability in a sample of geriatric individuals and its cl...
A Collaborative Endeavor
JCP’s Editor in Chief thanks reviewers, editorial board members, and editors for their contributions to the journal over t...
Clinical Effectiveness of Electroconvulsive Therapy for Psychotic vs Nonpsychotic Depression: A Cohort Study
Patients with major depression with psychotic features had higher response rates to ECT than those without psychotic featu...
Relationship Between Trauma, PTSD, and Schizophrenia: Relevance for Outcomes, Screening, and Interventions
The authors summarize the clinical relevance of trauma and PTSD in patients with schizophrenia and examine assessment and ...
Esketamine Nasal Spray vs Quetiapine Extended-Release: Examining Work Productivity Loss and Related Costs in Patients With Treatment-Resistant Depression
Esketamine was associated with significantly larger improvements in work productivity loss and related costs compared to q...
Ketamine vs Electroconvulsive Therapy in the Management of Treatment-Resistant Depression: Do We Need More Data?
Data suggest the difference between ketamine and ECT in efficacy for treatment-resistant depression may be smaller than pr...
COVID-19 Pandemic–Related Perceived Stress, Insomnia, Depression, and Anxiety Among Rural Primary Care Health Workers: A Mediation Analysis
This study assessed the prevalence of anxiety, depression, insomnia, and perceived stress, as well as the factors that med...
Suicides by Sodium Nitrite Reported to America’s Poison Centers: 2020–2023
During 2020-2023, the number of sodium nitrate exposure cases peaked at 39 in 2022, with a drop to 29 in 2023. Case fatali...
Psychological Challenges of Adults With Severe Mental Illness During the COVID-19 Pandemic
Adults with SMI diagnosed with COVID-19 and those who sheltered in place during lockdown experienced more severe psycholog...
Persistent Psychosis Induced by Cannabis Withdrawal
A 36-year-old man presented with complaints of suspiciousness, irritability, and reduced sleep for more than 2 months, whi...
Management of Insomnia in the General Hospital
Although the etiology of insomnia is often multi-factorial, both nonpharmacologic and various pharmacologic approaches can...
Efficacy and Safety of Sulforaphane Added to Antipsychotics for the Treatment of Negative Symptoms of Schizophrenia: A Randomized Controlled Trial
Add-on high dose sulforaphane may reduce negative symptoms in patients with schizophrenia, although the clinical significa...
Effect of Lemborexant on Daytime Functioning in Adults With Insomnia: Patient-Reported Outcomes From a Phase 3 Clinical Trial
Improved insomnia symptoms with lemborexant treatment may translate into improved daytime functioning.
Resilience and Vulnerability: Suicide-Specific Cognitions in a Nationally Representative Sample of US Military Veterans
This study examined data from a large, nationally representative sample of US veterans to determine the prevalence and cor...
Efficacy and Safety of BI 1358894 in Patients With Borderline Personality Disorder: Results of a Phase 2 Randomized, Placebo-Controlled, Parallel Group Dose-Ranging Trial
Although the primary endpoint was not met, BI 1358894 was well-tolerated with no increase in self-harm or suicidality.
Synopsis of the 2023 US Department of Veterans Affairs and US Department of Defense Clinical Practice Guideline for the Management of Bipolar Disorder
This synopsis focuses on clinically relevant recommendations related to identification and management of bipolar disorder,...
Sodium Valproate–Associated Psoriasis: A Case Report and Brief Literature Review
The authors present a rare case of exacerbation of psoriasiform eruptions in a patient who was prescribed sodium valproate...
Catatonia Associated With Post-Acute COVID-19 in a Young Child
A 4-year-old girl with high-functioning autism spectrum disorder experienced catatonia associated with the post-acute phas...
Baseline Cardiovascular Risk Factors in Patients With Severe Mental Illness (SMI) and Second Generation Antipsychotic Use From the Fixed Dose Intervention Trial of New England Enhancing Survival in SMI (FITNESS)
Despite well-documented cardiovascular disease (CVD) morbidity and mortality, CVD risks among people with severe mental il...
Inpatient Treatment of Suicidality: A Systematic Review of Clinical Trials
Effective, rapid treatments that target suicidality in psychiatric inpatients are scarce in the existing literature and in...
Effects of Intravenous Hydroxyzine Versus Haloperidol Monotherapy for Delirium: A Retrospective Study
Hydroxyzine showed a significantly higher rate of delirium improvement than haloperidol, with no significant difference in...
Maternal Cannabis Use During Pregnancy and Neuropsychiatric Adverse Outcomes During Childhood and Early Adult Life
Current research suggests that prenatal cannabis exposure is linked to many adverse outcomes, including psychosis pronenes...
Innovative Strands of Healing: Nurturing Recovery in a Case of Trichotillomania Via Tele-Based Habit Reversal Therapy
The authors present a case of trichotillomania in a patient who was managed via telepsychiatry-based habit reversal therap...
Affective, Behavioral, and Cognitive Symptoms Associated With Focal Impaired Awareness (Complex Partial) Seizures: Evaluation and Treatment
Focal impaired awareness seizures can look like other psychiatric, neurological, and medical presentations, and due to the...
Broad Differential Diagnoses in a Case of Catatonia Secondary to Clozapine Withdrawal
This case presents a complex clinical scenario in which no single diagnosis fully accounted for the presenting symptoms.
Geographical and Socioeconomic Disparities in Substance and Opioid Use Disorders Among Inflammatory Bowel Disease Hospitalizations in the United States From the National Inpatient Sample
A higher prevalence of SUD and opioid use disorder was found among hospitalizations for inflammatory bowel disease, and th...
Olanzapine/Samidorphan Effects on Weight Gain: An Individual Patient Data Meta-Analysis of Phase 2 and 3 Randomized Double-Blind Studies
Treatment with a combination of olanzapine and samidorphan was associated with less weight gain and reduced risk of reachi...
Discord and Distress: Cyberbullying and Adolescent Mental Health
Discord and Distress: Cyberbullying and Adolescent Mental Health
Two patients admitted to an inpatient psychiatric unit for suicidality cited interactions with users on the messaging app ...
Antipsychotic-Induced Tardive Lingual Dystonia Presenting With Bradycardia
Antipsychotic-Induced Tardive Lingual Dystonia Presenting With Bradycardia
The authors present a rare case of antipsychotic-induced lingual dystonia that led to hemodynamic changes in a 15-year-old...
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