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Modulation of lncRNA NEAT1 overturns the macrophages based immune response in M. tuberculosis infected patients via miR-373 regulation
Modulation of lncRNA NEAT1 overturns the macrophages based immune response in M. tuberculosis infected patients via miR-373 regulation
There is a lack of studies which explore and clarify the interactions that occur between host macrophage and Mycobacterium...
lncRNA MIAT promotes luminal B breast cancer cell proliferation, migration, and invasion in vitro
lncRNA MIAT promotes luminal B breast cancer cell proliferation, migration, and invasion in vitro
Long noncoding RNAs (lncRNAs) play a role in the emergence and progression of several human tumors, including luminal B br...
Identification of co-expressed genes and immune infiltration features related to the progression of atherosclerosis
Identification of co-expressed genes and immune infiltration features related to the progression of atherosclerosis
Atherosclerosis is a chronic inflammatory disease that affects arterial walls and is a leading cause of cardiovascular dis...
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
In the era of genomic-assisted breeding for crop improvement, developing new molecular markers and validating them for use...
Comparing Bayesian models for the genetic evaluation of oocytes and embryo counts in Dairy Gir cattle
Comparing Bayesian models for the genetic evaluation of oocytes and embryo counts in Dairy Gir cattle
Count traits are usually explored in livestock breeding programs, and they usually do not fit into normal distribution, re...
ZNF26-Associated Genes as Prognostic Signatures in Colorectal Cancer with Broad Therapeutic Implications
ZNF26-Associated Genes as Prognostic Signatures in Colorectal Cancer with Broad Therapeutic Implications
The identification of biomarkers correlated with colorectal cancer (CRC) prognosis holds substantial importance from both ...
The use of SNP markers for cattle breed identification
The use of SNP markers for cattle breed identification
A potential application of single nucleotide polymorphisms (SNPs) in animal husbandry and production is identification of ...
Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population
Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population
Genetic cardiomyopathies (CM) are disorders that affect morphology and function of cardiac muscle. Significant number of g...
Long non-coding RNA variability in porcine skeletal muscle
Long non-coding RNA variability in porcine skeletal muscle
Recently, numerous studies including various tissues have been carried out on long non-coding RNAs (lncRNAs), but still, i...
Exploring genomic inbreeding and selection signatures in a commercial Brangus herd through functional annotation
Exploring genomic inbreeding and selection signatures in a commercial Brangus herd through functional annotation
Composite breeds, including Brangus, are widely utilized in subtropical and tropical regions to harness the advantages of ...
In silico approach for the identification of tRNA-derived small non-coding RNAs in SARS-CoV infection
In silico approach for the identification of tRNA-derived small non-coding RNAs in SARS-CoV infection
tsRNAs (tRNA-derived small non-coding RNAs), including tRNA halves (tiRNAs) and tRNA fragments (tRFs), have been implicate...
Blood-based microRNA profiling unveils complex molecular dynamics in breast cancer
Blood-based microRNA profiling unveils complex molecular dynamics in breast cancer
Breast cancer, a genetically intricate disease with diverse subtypes, exhibits heightened incidence globally. In this stud...
Integrative analysis of homologous recombination repair patterns unveils prognostic signatures and immunotherapeutic insights in breast cancer
Integrative analysis of homologous recombination repair patterns unveils prognostic signatures and immunotherapeutic insights in breast cancer
Globally, breast cancer (BC) is the leading cause of female death and morbidity. Homologous recombination repair (HRR) is ...
Gene-edited cells: novel allogeneic gene/cell therapy for epidermolysis bullosa
Gene-edited cells: novel allogeneic gene/cell therapy for epidermolysis bullosa
Epidermolysis bullosa (EB) is a group of rare genetic skin fragility disorders, which are hereditary. These disorders are ...
Identification and validation of a novel nine-gene prognostic signature of stem cell characteristic in hepatocellular carcinoma
Identification and validation of a novel nine-gene prognostic signature of stem cell characteristic in hepatocellular carcinoma
Currently, cancer stem cells (CSCs) are regarded as the most promising target for cancer therapy due to their close associ...
Transcriptome profiling and metabolic pathway analysis towards reliable biomarker discovery in early-stage lung cancer
Transcriptome profiling and metabolic pathway analysis towards reliable biomarker discovery in early-stage lung cancer
Earlier diagnosis of lung cancer is crucial for reducing mortality and morbidity in high-risk patients. Liquid biopsy is a...
Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
Novel DNA methylation biomarkers for early diagnosis of oral tongue squamous cell carcinoma (OTSCC)
Oral tongue squamous cell carcinoma (OTSCC) is the most common malignancy type among males across the world. However, anal...
Single-cell integrated transcriptomics reveals the role of keratinocytes in head and neck squamous cell carcinoma
Single-cell integrated transcriptomics reveals the role of keratinocytes in head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignant tumor with significant morbidity and mortality. Und...
Establishment of a cloning-free CRISPR/Cas9 protocol to generate large deletions in the bovine MDBK cell line
Establishment of a cloning-free CRISPR/Cas9 protocol to generate large deletions in the bovine MDBK cell line
The CRISPR/Cas9 technique applied to modify the cattle genome has value in increasing animal health and welfare. Here, we ...
Novel FOXP2 variant associated with speech and language dysfunction in a Chinese family and literature review
Novel FOXP2 variant associated with speech and language dysfunction in a Chinese family and literature review
Since its initial identification, the Forkhead Box P2 gene (FOXP2) has maintained its singular status as the archetypal mo...
A case of non-mosaic X trisomy (65,XXX) in a Thoroughbred mare confirmed by cytogenetic and molecular analysis
A case of non-mosaic X trisomy (65,XXX) in a Thoroughbred mare confirmed by cytogenetic and molecular analysis
A 9-year-old Thoroughbred mare with normal external genitalia and regular oestrus symptoms was gynecologically examined pr...
Diallel analysis of common bean (Phaseolus vulgaris L.) genotypes for seed dietary fibre, carbohydrate, calcium and phosphorus contents
Diallel analysis of common bean (Phaseolus vulgaris L.) genotypes for seed dietary fibre, carbohydrate, calcium and phosphorus contents
Genetic information of bean seed traits can be an immense help to the breeder in selection of suitable genotypes and the a...
Uncovering the role of aquaporin and chromobox family members as potential biomarkers in head and neck squamous cell carcinoma via integrative multiomics and in silico approach
Uncovering the role of aquaporin and chromobox family members as potential biomarkers in head and neck squamous cell carcinoma via integrative multiomics and in silico approach
Head and neck squamous cell carcinoma (HNSC) is a diverse group of tumors arising from oral cavity, oropharynx, larynx, an...
Genomic Profiling Reveals Immune-Related Gene Differences in Lung Cancer Patients Stratified by PD1/PDL1 Expression: Implications for Immunotherapy Efficacy
Genomic Profiling Reveals Immune-Related Gene Differences in Lung Cancer Patients Stratified by PD1/PDL1 Expression: Implications for Immunotherapy Efficacy
Lung cancer remains a leading cause of global cancer-related mortality, and the exploration of innovative therapeutic appr...
Triticale field phenotyping using RGB camera for ear counting and yield estimation
Triticale field phenotyping using RGB camera for ear counting and yield estimation
Triticale (X Triticosecale Wittmack), a wheat-rye small grain crop hybrid, combines wheat and rye attributes in one hexapl...
Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma
Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma
Long non-coding RNAs (lncRNAs) have been implicated in carcinogenesis and progression of hepatocellular carcinoma (HCC). T...
The role of multidisciplinary diagnostic and therapeutic model of care in Lamb-Shaffer syndrome - case report
The role of multidisciplinary diagnostic and therapeutic model of care in Lamb-Shaffer syndrome - case report
This case study illustrates a multidisciplinary diagnostic and therapeutic model of care for a 7-year-old male with Lamb&#...
Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana
Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana
Deteriorating climatic conditions and increasing human population necessitate the development of robust plant varieties re...
Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification
Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification
Human epidermal growth factor receptor 2 (HER2) overexpression and activation are crucial for trastuzumab resistance in HE...
Assessing cytotoxicity and endoplasmic reticulum stress in human blood–brain barrier cells due to silver and copper oxide nanoparticles
Assessing cytotoxicity and endoplasmic reticulum stress in human blood–brain barrier cells due to silver and copper oxide nanoparticles
In recent years, it has been generally accepted that metal-based nanoparticles (NPs) may induce stress in the endoplasmic ...
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