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Clinical features of immature leukemias in children
Clinical features of immature leukemias in children
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL), mixed phenotypic acute leukemia (MPAL), and acute myeloid l...
Comprehensive analysis of microRNAs modulated by histone deacetylase inhibitors identifies microRNA-7-5p with anti-myeloma effect
Comprehensive analysis of microRNAs modulated by histone deacetylase inhibitors identifies microRNA-7-5p with anti-myeloma effect
Basic research to expand treatment options for multiple myeloma is greatly needed due to the refractory nature of the dise...
CAR-T cell therapy in AML: recent progress and future perspectives
CAR-T cell therapy in AML: recent progress and future perspectives
Despite several small-molecule drugs that have revolutionized the current treatment strategy for acute myeloid leukemia (A...
Heparin-induced thrombocytopenia with very high antibody titer is associated with slower platelet recovery and higher risk of thrombosis
Heparin-induced thrombocytopenia with very high antibody titer is associated with slower platelet recovery and higher risk of thrombosis
Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder mediated by platelet-activating antibodies targeting pl...
Lenalidomide and pomalidomide modulate hematopoietic cell expansion and differentiation in the presence of MSC
Lenalidomide and pomalidomide modulate hematopoietic cell expansion and differentiation in the presence of MSC
Cytopenia is a well-documented complication in the treatment of hematological malignancies with lenalidomide and pomalidom...
Trametinib for a child with refractory Rosai–Dorfman–Destombes disease harboring a novel somatic mutation in MAP2K1
Trametinib for a child with refractory Rosai–Dorfman–Destombes disease harboring a novel somatic mutation in MAP2K1
Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytosis characterized by accumulation of S100 +...
Dynamic changes in femoral bone marrow MRI in patients with chronic myelogenous leukemia
Dynamic changes in femoral bone marrow MRI in patients with chronic myelogenous leukemia
Cite this articleIkeda, S., Suzuki, M., Tsunoda, S. et al. Dynamic changes in femoral bone marrow MRI in patients with chr...
Survival impact of response within the first year in a multicenter prospective observational study of chronic GVHD in a Japanese cohort
Survival impact of response within the first year in a multicenter prospective observational study of chronic GVHD in a Japanese cohort
A prospective multicenter observational study of organ response was conducted in patients with chronic GVHD diagnosed by t...
Asciminib in Patients With CML-CP Previously Treated With ≥ 2 Tyrosine Kinase Inhibitors: 96-Week Results From the Japanese Subgroup Analysis of the ASCEMBL Study
Asciminib in Patients With CML-CP Previously Treated With ≥ 2 Tyrosine Kinase Inhibitors: 96-Week Results From the Japanese Subgroup Analysis of the ASCEMBL Study
Asciminib is a first-in-class BCR::ABL1 inhibitor that Specifically Targets the ABL1 Myristoyl Pocket (STAMP). It is appro...
Detection of factor XIII inhibitors in 33 patients with autoimmune factor XIII deficiency in Japan
Detection of factor XIII inhibitors in 33 patients with autoimmune factor XIII deficiency in Japan
Autoimmune factor XIII (FXIII) deficiency (AiF13D) is a rare hemorrhagic disease. The anti-FXIII autoantibodies that cause...
CRISPR/Cas9 gene editing clarifies the role of CD33 SNP rs12459419 in gemtuzumab ozogamicin-mediated cytotoxicity
CRISPR/Cas9 gene editing clarifies the role of CD33 SNP rs12459419 in gemtuzumab ozogamicin-mediated cytotoxicity
The single-nucleotide polymorphism (SNP) rs12459419 is located at the intron/exon junction of CD33 exon2. When exon2 is sk...
Myeloid sarcoma with plasmacytoid dendritic cell-like proliferation associated with IKZF1, ETV6 and DNMT3A mutations
Myeloid sarcoma with plasmacytoid dendritic cell-like proliferation associated with IKZF1, ETV6 and DNMT3A mutations
The classification of clonal plasmacytoid dendritic cell (pDC) proliferation associated with myeloid neoplasms remains a t...
Cellular and humoral immunogenicity against SARS-CoV-2 vaccination or infection is associated with the memory phenotype of T- and B-lymphocytes in adult allogeneic hematopoietic cell transplant recipients
Cellular and humoral immunogenicity against SARS-CoV-2 vaccination or infection is associated with the memory phenotype of T- and B-lymphocytes in adult allogeneic hematopoietic cell transplant recipients
We conducted a cross-sectional study to evaluate cellular and humoral immunogenicity against severe acute respiratory synd...
GPS2 promotes erythroid differentiation in K562 erythroleukemia cells primarily via NCOR1
GPS2 promotes erythroid differentiation in K562 erythroleukemia cells primarily via NCOR1
G protein pathway suppressor 2 (GPS2) has been shown to play a pivotal role in human and mouse definitive erythropoiesis i...
A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia
A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia
NS-87/CPX-351 is a dual-drug liposomal encapsulation of cytarabine and daunorubicin. NS-87/CPX-351 exerts antileukemic act...
Allogeneic hematopoietic stem cell transplantation after mogamulizumab in T-cell lymphoma patients: a retrospective analysis
Allogeneic hematopoietic stem cell transplantation after mogamulizumab in T-cell lymphoma patients: a retrospective analysis
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an important therapy for patients with T-cell lymphomas,...
Long-range and real-time PCR identification of a large SERPINC1 deletion in a patient with antithrombin deficiency
Long-range and real-time PCR identification of a large SERPINC1 deletion in a patient with antithrombin deficiency
Congenital antithrombin (AT) or serpin C1 deficiency, caused by a SERPINC1 abnormality, is a high-risk factor for venous t...
New classifications of B-cell neoplasms: a comparison of 5th WHO and International Consensus classifications
New classifications of B-cell neoplasms: a comparison of 5th WHO and International Consensus classifications
In 2024, the World Health Organization (WHO) launched a new classification of lymphoid neoplasms, a revision of the previo...
Clinical management of iron deficiency anemia in Japan: iron prescription patterns, treatment effectiveness, and assessments
Clinical management of iron deficiency anemia in Japan: iron prescription patterns, treatment effectiveness, and assessments
Iron deficiency anemia is one of the most common types of anemia, but real-world clinical management practices in Japan ar...
B-cell prolymphocytic leukemia: an enduring bona fide entity
B-cell prolymphocytic leukemia: an enduring bona fide entity
B-cell prolymphocytic leukemia (B-PLL) was recognized as a distinct entity in the fourth edition of the World Health Organ...
Chemotherapy-induced aseptic thrombophlebitis with an air bubble in the thrombus
Chemotherapy-induced aseptic thrombophlebitis with an air bubble in the thrombus
Conflict of interest The authors have no conflicts of interest to d...
WT1-guided pre-emptive therapy after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia
WT1-guided pre-emptive therapy after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia
Measurable residual disease (MRD)-guided pre-emptive therapies are now widely used to prevent post-transplant hematologica...
Ruxolitinib in steroid-refractory acute graft-vs-host disease: Japanese subgroup analysis of the randomized REACH2 trial
Ruxolitinib in steroid-refractory acute graft-vs-host disease: Japanese subgroup analysis of the randomized REACH2 trial
Acute graft-versus-host disease (aGvHD) is a major complication after allogeneic hematopoietic stem cell transplantation i...
Novel CAR T cell therapies for patients with large B cell lymphoma
Novel CAR T cell therapies for patients with large B cell lymphoma
Approximately 60–70% of patients with large B cell lymphoma (LBCL) achieve long-term remission or a cure after initi...
Current progress of CAR-T-cell therapy for patients with multiple myeloma
Current progress of CAR-T-cell therapy for patients with multiple myeloma
Currently available chimeric antigen receptor (CAR)-engineered T-cell therapies targeting B-cell maturation antigen (BCMA)...
A review of the Augustine blood group system
A review of the Augustine blood group system
Augustine is a newly identified blood group system comprising four antigens, one of which is the high-frequency antigen At...
Retrospectively diagnosed autoimmune VWF deficiency in a patient with repeated hemorrhagic events after two common colds
Retrospectively diagnosed autoimmune VWF deficiency in a patient with repeated hemorrhagic events after two common colds
Autoimmune von Willebrand factor (VWF) deficiency (AiVWFD) caused by anti-VWF autoantibodies is a rare bleeding disorder, ...
Metabolic dependencies of acute myeloid leukemia stem cells
Metabolic dependencies of acute myeloid leukemia stem cells
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy primarily driven by an immature population of AML c...
Outcome of 3q26.2/MECOM rearrangements in chronic myeloid leukemia
Outcome of 3q26.2/MECOM rearrangements in chronic myeloid leukemia
To evaluate the outcomes of patients with 3q26.2/MECOM-rearranged chronic myeloid leukemia (CML). We reviewed consecutive ...
Serum monoclonal immunoglobulin light-chain detection differs between immunofixation electrophoresis methods in patients with AL amyloidosis
Serum monoclonal immunoglobulin light-chain detection differs between immunofixation electrophoresis methods in patients with AL amyloidosis
Serum immunofixation electrophoresis (IFE) is often performed for screening monoclonal proteins (M proteins) in immunoglob...
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