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Association between early anti-cytomegalovirus therapy and the incidence of chronic graft-versus-host disease
Association between early anti-cytomegalovirus therapy and the incidence of chronic graft-versus-host disease
Ganciclovir and foscarnet are two representative anti-cytomegalovirus (CMV) agents. A previous regional study revealed a l...
Iron deficiency and phlebotomy in patients with polycythemia vera
Iron deficiency and phlebotomy in patients with polycythemia vera
Polycythemia vera (PV) is a myeloproliferative neoplasm that is associated with an elevated risk of thrombosis. Treatment ...
A phase 1/2 study of gilteritinib in combination with chemotherapy in newly diagnosed patients with AML in Asia
A phase 1/2 study of gilteritinib in combination with chemotherapy in newly diagnosed patients with AML in Asia
This interim analysis of a phase 1/2, open-label, single-arm study assessed the safety, efficacy, and pharmacokinetics of ...
Quizartinib with donor lymphocyte infusion for post-transplant relapse of FLT3-ITD-positive acute myeloid leukemia
Quizartinib with donor lymphocyte infusion for post-transplant relapse of FLT3-ITD-positive acute myeloid leukemia
FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD)-positive acute myeloid leukemia (AML) has a poor prognos...
Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan
Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan
We report the first large-scale retrospective cohort study on adolescent and young adult (AYA) polycythemia vera (PV) and ...
Assay variables and early clinical evaluation of low-angle light scattering for platelet function analysis
Assay variables and early clinical evaluation of low-angle light scattering for platelet function analysis
The recently developed platelet aggregation technique based on low-angle light scattering (LaSca) in diluted platelet-rich...
Long-term safety profile of sutimlimab in adult Japanese patients with cold agglutinin disease
Long-term safety profile of sutimlimab in adult Japanese patients with cold agglutinin disease
Sutimlimab, a complement inhibitor, has recently been approved in Japan for treating cold agglutinin disease (CAD). We rep...
Ruxolitinib for steroid-refractory chronic graft-versus-host disease: Japanese subgroup analysis of REACH3 study
Ruxolitinib for steroid-refractory chronic graft-versus-host disease: Japanese subgroup analysis of REACH3 study
Ruxolitinib, a Janus kinase (JAK1–JAK2) inhibitor, has demonstrated safety and efficacy in patients with graft-versu...
Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera
Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera
Ropeginterferon alfa-2b (ropegIFN), a new-generation interferon-based agent, has been approved in Japan for patients with ...
Long-term safety and effectiveness of romiplostim for chronic idiopathic thrombocytopenic purpura in real-world settings
Long-term safety and effectiveness of romiplostim for chronic idiopathic thrombocytopenic purpura in real-world settings
Idiopathic thrombocytopenic purpura (ITP), an autoimmune hematologic disorder characterized by severe platelet count reduc...
Silent inactivation of asparaginase in Japan: results of the prospective ALL-ASP19 trial
Silent inactivation of asparaginase in Japan: results of the prospective ALL-ASP19 trial
Silent inactivation (SI) of L-asparaginase (ASP) is a phenomenon by which a neutralizing antibody for ASP (AAA) decreases ...
Relationship between hemoglobinopathies and male infertility: a scoping review
Relationship between hemoglobinopathies and male infertility: a scoping review
Infertility is a common issue that threatens couples worldwide. Infertility can result from the male or female partner alo...
Adult-onset severe paroxysmal cold hemoglobinuria after COVID-19 successfully treated with sutimlimab
Adult-onset severe paroxysmal cold hemoglobinuria after COVID-19 successfully treated with sutimlimab
Paroxysmal cold hemoglobinuria (PCH) is a form of cold autoimmune hemolytic anemia characterized by the presence of the Do...
Expansion effect of romiplostim on hematopoietic stem and progenitor cells versus thrombopoietin and eltrombopag
Expansion effect of romiplostim on hematopoietic stem and progenitor cells versus thrombopoietin and eltrombopag
Romiplostim, a thrombopoietin (TPO) receptor agonist, is a clinically approved drug that is clearly effective in reconstit...
Newly diagnosed multiple myeloma with bleeding and coagulation abnormalities caused by a thrombin-inhibiting substance
Newly diagnosed multiple myeloma with bleeding and coagulation abnormalities caused by a thrombin-inhibiting substance
Approximately 7% of patients with newly diagnosed multiple myeloma (MM) experience bleeding complications with varying cau...
Mitochondrial dynamics as a potential therapeutic target in acute myeloid leukemia
Mitochondrial dynamics as a potential therapeutic target in acute myeloid leukemia
Acute myeloid leukemia (AML) cells are highly dependent on oxidative phosphorylation and the mitochondrial dynamics regula...
Comparison of disease and risk classifications of AML before and after incorporation of NGS analysis of bone marrow samples
Comparison of disease and risk classifications of AML before and after incorporation of NGS analysis of bone marrow samples
Mutation profiling by next-generation sequencing (NGS) has facilitated understanding of the molecular pathogenesis of acut...