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Establishment of a high-risk pediatric AML-derived cell line YCU-AML2 with genetic and metabolic vulnerabilities
Establishment of a high-risk pediatric AML-derived cell line YCU-AML2 with genetic and metabolic vulnerabilities
The prognosis of acute myeloid leukemia (AML) with KMT2A::MLLT3 rearrangement and MECOM overexpression and/or KRAS mutatio...
Long-term safety and efficacy of fostamatinib in Japanese patients with primary immune thrombocytopenia
Long-term safety and efficacy of fostamatinib in Japanese patients with primary immune thrombocytopenia
Fostamatinib had superior efficacy to a placebo and acceptable safety profiles for at least 1 year in a phase 3 study of J...
Venetoclax and azacitidine in combination with homoharringtonine, cytarabine, and aclarubicin for salvage therapy of relapsed/refractory T cell acute lymphoblastic leukemia
Venetoclax and azacitidine in combination with homoharringtonine, cytarabine, and aclarubicin for salvage therapy of relapsed/refractory T cell acute lymphoblastic leukemia
The treatment of relapsed/refractory T cell acute lymphoblastic leukemia (R/R T-ALL) is a significant challenge in hematol...
The medium-fluorescence reticulocyte ratio is an independent predictor of G6PD deficiency neonates
The medium-fluorescence reticulocyte ratio is an independent predictor of G6PD deficiency neonates
G6PD deficiency is a potentially life-threatening condition in neonates presenting with hyperbilirubinemia. This study aim...
Post-transplant TKIs for Ph+ ALL: practices to date and clinical significance
Post-transplant TKIs for Ph+ ALL: practices to date and clinical significance
Post-transplant tyrosine kinase inhibitors (TKIs) show promise in preventing relapse after allogeneic hematopoietic cell t...
JSH practical guidelines for hematological malignancies, 2023: leukemia-6. Myelodysplastic syndromes (MDS)
JSH practical guidelines for hematological malignancies, 2023: leukemia-6. Myelodysplastic syndromes (MDS)
Conflict of interest YM has received per diem, including speaking f...
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 3: solid cancers and vascular abnormalities
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 3: solid cancers and vascular abnormalities
This study discusses disseminated intravascular coagulation (DIC) associated with solid cancers and various vascular abnor...
A case of late-onset sinusoidal obstruction syndrome diagnosed histologically before meeting diagnostic criteria
A case of late-onset sinusoidal obstruction syndrome diagnosed histologically before meeting diagnostic criteria
Sinusoidal obstruction syndrome (SOS), also known as hepatic veno-occlusive disease (VOD), is a life-threatening complicat...
Nodal mature plasmacytoid dendritic cell proliferation mimicking lymphoma in a patient with CALR-mutated myelofibrosis
Nodal mature plasmacytoid dendritic cell proliferation mimicking lymphoma in a patient with CALR-mutated myelofibrosis
Cite this articleMagnoli, F., Brociner, M. & La Rosa, S. Nodal mature plasmacytoid dendritic cell proliferation mimick...
Pseudo-Chediak–Higashi inclusions and Auer rods in a case of therapy-related acute monocytic leukemia
Pseudo-Chediak–Higashi inclusions and Auer rods in a case of therapy-related acute monocytic leukemia
Conflict of interest The author has no conflict of interest. ...
Adjunctive effects of eltrombopag on immunosuppressive therapy for childhood aplastic anemia
Adjunctive effects of eltrombopag on immunosuppressive therapy for childhood aplastic anemia
Eltrombopag is used with first-line immunosuppressive therapy for adult aplastic anemia, although its practical utility in...
Isatuximab plus pomalidomide and dexamethasone in frail individuals with relapsed/refractory multiple myeloma in Japan
Isatuximab plus pomalidomide and dexamethasone in frail individuals with relapsed/refractory multiple myeloma in Japan
This post-marketing surveillance (PMS) assessed the safety and effectiveness of isatuximab plus pomalidomide and dexametha...
Cost-effectiveness of ferric citrate hydrate in patients with iron deficiency anemia
Cost-effectiveness of ferric citrate hydrate in patients with iron deficiency anemia
We investigated the cost-effectiveness of treating iron deficiency anemia (IDA) with ferric citrate hydrate (FC) in Japan....
DREAMM-11, Part 2: Japanese phase I trial of belantamab mafodotin combination therapies in relapsed/refractory multiple myeloma
DREAMM-11, Part 2: Japanese phase I trial of belantamab mafodotin combination therapies in relapsed/refractory multiple myeloma
DREAMM-11 (NCT03828292) was a Phase 1, open-label, dose-escalation study of belantamab mafodotin in Japanese patients with...
A 25-year clonal resurrection in adult T-cell leukemia-lymphoma relapse
A 25-year clonal resurrection in adult T-cell leukemia-lymphoma relapse
Here, we report a rare case of relapsed adult T-cell leukemia-lymphoma (ATL) with evidence of clonal relapse 26 y...
Carcinocythemia diagnosed on peripheral blood clot sections
Carcinocythemia diagnosed on peripheral blood clot sections
Authors and AffiliationsDepartment of Haematological Medicine, King’s College Hospital NHS Foundation Trust, Denmark Hill,...
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 1: sepsis
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 1: sepsis
The Japanese Society on Thrombosis and Hemostasis (JSTH) published the first-ever disseminated intravascular coagulation (...
A practice-oriented genome-profiling study for acute myeloid leukemia using the novel HANDLE system: HM-screen-JAPAN02
A practice-oriented genome-profiling study for acute myeloid leukemia using the novel HANDLE system: HM-screen-JAPAN02
HM-SCREEN-Japan is a multicenter collaborative project in Japan to evaluate the clinical utility of a cancer genome panel ...
Outcomes of allogeneic SCT versus tisagenlecleucel in patients with R/R LBCL and poor prognostic factors
Outcomes of allogeneic SCT versus tisagenlecleucel in patients with R/R LBCL and poor prognostic factors
This study investigated the efficacy of tisagenlecleucel (tisa-cel) and allogeneic hematopoietic stem cell transplantation...
Chimerism analysis by ABO blood group genotyping with digital droplet PCR
Chimerism analysis by ABO blood group genotyping with digital droplet PCR
Chimerism analysis is an important post-transplant assessment for allogeneic hematopoietic stem cell transplant (HCT) reci...
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 2: hematologic malignancy
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 2: hematologic malignancy
Disseminated intravascular coagulation (DIC) associated with hematologic malignancies, particularly acute promyelocytic le...
Treatment trends and risks of corticosteroid use in adult primary immune thrombocytopenia: a claims database study in Japan
Treatment trends and risks of corticosteroid use in adult primary immune thrombocytopenia: a claims database study in Japan
Recent trends in the treatment of primary immune thrombocytopenia (ITP) were investigated using a claims database that inc...
Inotuzumab ozogamicin for relapse prevention in a boy with Down syndrome and relapsed acute lymphoblastic leukemia
Inotuzumab ozogamicin for relapse prevention in a boy with Down syndrome and relapsed acute lymphoblastic leukemia
Inotuzumab ozogamicin (InO), a CD22-directed antibody conjugated to calicheamicin, has demonstrated excellent efficacy in ...
Temporal changes in corticosteroid dose during ibrutinib treatment in patients with cGVHD and pulmonary involvement
Temporal changes in corticosteroid dose during ibrutinib treatment in patients with cGVHD and pulmonary involvement
The GVH3001 study assessed the efficacy and safety of ibrutinib in Japanese patients with steroid-dependent or -refractory...
Graft CD8+ T cells for improving event-free survival after T cell-replete haploidentical stem cell transplantation in children with hematological malignancies
Graft CD8+ T cells for improving event-free survival after T cell-replete haploidentical stem cell transplantation in children with hematological malignancies
T cell-replete haploidentical hematopoietic stem cell transplantation (TCR-haplo-HSCT) is a potentially curative therapy f...
Clonal hematopoiesis in cancer predisposition syndromes
Clonal hematopoiesis in cancer predisposition syndromes
After recent advances in sequencing technologies led to the discovery of novel genes associated with predisposition to hem...
Acute myeloid leukemia with NUP98::RARG rearrangement: a case report and review of the relevant literature
Acute myeloid leukemia with NUP98::RARG rearrangement: a case report and review of the relevant literature
We herein report a rare case of acute myeloid leukemia (AML) with t(11;12)(p15;q13) and NUP98::RARG, which seems to be inv...
A clot waveform analysis-based system for differential diagnosis of prolonged activated partial thromboplastin time in plasma samples
A clot waveform analysis-based system for differential diagnosis of prolonged activated partial thromboplastin time in plasma samples
Prolonged activated partial thromboplastin time (aPTT) in plasma samples requires quick and accurate differential diagnosi...
Reduced OTUD7B expression correlates with poor prognosis in PTCL via non-canonical NF-κB
Reduced OTUD7B expression correlates with poor prognosis in PTCL via non-canonical NF-κB
Peripheral T cell lymphoma (PTCL) is an aggressive and highly heterogeneous lymphoma with a bleak prognosis, highlighting ...
Comparison of busulfan pharmacokinetics between four-times-daily and once-daily administration in pediatric patients: a preliminary prospective observational trial
Comparison of busulfan pharmacokinetics between four-times-daily and once-daily administration in pediatric patients: a preliminary prospective observational trial
Therapeutic drug monitoring (TDM) of busulfan (BU) is useful for achieving the target area under the curve (AUC) because i...
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