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An unfavorable and a successful pregnancy outcome during and after treatment of gamma heavy chain disease
An unfavorable and a successful pregnancy outcome during and after treatment of gamma heavy chain disease
Gamma heavy chain disease (gHCD) is a rare B-cell lymphoproliferative disorder that mostly occurs after childbearing age. ...
Cytomegalovirus infection during daratumumab therapy in patients with newly diagnosed multiple myeloma
Cytomegalovirus infection during daratumumab therapy in patients with newly diagnosed multiple myeloma
The introduction of daratumumab has improved treatment outcomes for multiple myeloma (MM). However, infectious complicatio...
Bernard–Soulier syndrome caused by a novel GP1BB variant and 22q11.2 deletion
Bernard–Soulier syndrome caused by a novel GP1BB variant and 22q11.2 deletion
Bernard–Soulier syndrome (BSS) is caused by defects in GP1BA, GP1BB, or GP9 genes. Patients with 22q11.2 deletion sy...
Honeycomb lung appearance accompanied by pediatric Langerhans cell histiocytosis: changes in imaging findings following chemotherapy
Honeycomb lung appearance accompanied by pediatric Langerhans cell histiocytosis: changes in imaging findings following chemotherapy
Cite this articleSakamoto, K., Miyazaki, O. & Shioda, Y. Honeycomb lung appearance accompanied by pediatric Langerhans...
Spontaneous regression of multiple solitary plasmacytoma harboring Epstein–Barr virus: a case report and literature review
Spontaneous regression of multiple solitary plasmacytoma harboring Epstein–Barr virus: a case report and literature review
We report a rare case of spontaneous regression (SR) in an elderly untreated patient with multiple solitary plasmacytoma (...
Bispecific antibodies for multiple myeloma: past, present and future
Bispecific antibodies for multiple myeloma: past, present and future
Despite the development of various therapeutic agents, multiple myeloma remains incurable. Recently, T-cell redirected imm...
A phase 2, open-label study of ibrutinib plus rituximab in Japanese patients with Waldenstrom’s macroglobulinemia
A phase 2, open-label study of ibrutinib plus rituximab in Japanese patients with Waldenstrom’s macroglobulinemia
Ibrutinib is a first-in-class Bruton kinase inhibitor against B-cell neoplasms including Waldenström macroglobulinemi...
Optimized BEAC conditioning regimen improves clinical outcomes of autologous hematopoietic stem cell transplantation in non-Hodgkin lymphomas
Optimized BEAC conditioning regimen improves clinical outcomes of autologous hematopoietic stem cell transplantation in non-Hodgkin lymphomas
The conditioning regimen is an important part of autologous hematopoietic stem cell transplantation (ASCT). We explored th...
Changes in chronic myeloid leukemia treatment modalities and outcomes after introduction of second-generation tyrosine kinase inhibitors as first-line therapy: a multi-institutional retrospective study by the CML Cooperative Study Group
Changes in chronic myeloid leukemia treatment modalities and outcomes after introduction of second-generation tyrosine kinase inhibitors as first-line therapy: a multi-institutional retrospective study by the CML Cooperative Study Group
This study investigated changes in treatment modalities and outcomes of chronic myeloid leukemia in the chronic phase (CP-...
Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid
Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid
As multiple myeloma (MM) progresses, immune effector cells decrease in number and function and become exhausted. This rema...
Tumor lysis syndrome in induction therapy for acute myeloid leukemia before the rasburicase era
Tumor lysis syndrome in induction therapy for acute myeloid leukemia before the rasburicase era
Guidelines recommend rasburicase for high-risk patients to prevent tumor lysis syndrome (TLS). However, little information...
Optimizing random skin biopsies: a review of techniques and indications for intravascular large B-cell lymphoma
Optimizing random skin biopsies: a review of techniques and indications for intravascular large B-cell lymphoma
Intravascular large B-cell lymphoma (IVLBCL), a rare subtype of malignant lymphoma, is diagnosed by observation of intrava...
In memory of Prof. Makio Ogawa
In memory of Prof. Makio Ogawa
It is with deep sorrow that we announce the passing of Dr. Makio Ogawa, a pioneer and...
A prospective study of zanubrutinib, a Bruton tyrosine kinase inhibitor, in relapsed/refractory idiopathic multicentric Castleman disease
A prospective study of zanubrutinib, a Bruton tyrosine kinase inhibitor, in relapsed/refractory idiopathic multicentric Castleman disease
Relapsed and refractory (R/R) idiopathic multicentric Castleman disease (iMCD) is a clinical challenge with no standard tr...
Efficacy of daratumumab in newly diagnosed multiple myeloma patients with 1q21 gain
Efficacy of daratumumab in newly diagnosed multiple myeloma patients with 1q21 gain
Gain and amplification of 1q21 (1q21+) are adverse chromosomal aberrations of multiple myeloma (MM) that lead to refractor...
Primary analysis of a prospective cohort study of Japanese patients with plasma cell neoplasms in the novel drug era (2016–2021)
Primary analysis of a prospective cohort study of Japanese patients with plasma cell neoplasms in the novel drug era (2016–2021)
The emergence of novel drugs has significantly improved outcomes of patients with plasma cell neoplasms (PCN). The Japanes...
Hereditary TTP/Upshaw–Schulman syndrome: the ductus arteriosus controls newborn survival
Hereditary TTP/Upshaw–Schulman syndrome: the ductus arteriosus controls newborn survival
Hereditary TTP (hTTP), termed Upshaw–Schulman syndrome, is an ultra-rare disorder caused by a severe deficiency of p...
Vitamin B12 deficiency-induced megaloblastic anemia in a pediatric patient with autism spectrum disorder with a chronically unbalanced diet
Vitamin B12 deficiency-induced megaloblastic anemia in a pediatric patient with autism spectrum disorder with a chronically unbalanced diet
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a lack of behavioral flexibility and ster...
Sustained remission after cord blood transplantation for breast cancer with lung metastases and myelodysplastic syndrome
Sustained remission after cord blood transplantation for breast cancer with lung metastases and myelodysplastic syndrome
Allogenic hematopoietic stem cell transplantation (allo-HSCT) is not a standard therapy for solid cancer because of its hi...
Post-marketing surveillance of the safety and effectiveness of nivolumab for classic Hodgkin lymphoma in Japan
Post-marketing surveillance of the safety and effectiveness of nivolumab for classic Hodgkin lymphoma in Japan
Nivolumab was approved for relapsed/refractory classic Hodgkin lymphoma (cHL) in Japan in 2016. After its approval, a pros...
Platelet and large platelet ratios are useful in predicting severity of COVID-19
Platelet and large platelet ratios are useful in predicting severity of COVID-19
The role of platelets in coronavirus disease (COVID-19) severity requires further exploration. To determine whether the pl...
Aortitis after switching short-acting granulocyte colony-stimulating factors in a lymphoma patient with HLA-B52
Aortitis after switching short-acting granulocyte colony-stimulating factors in a lymphoma patient with HLA-B52
Aortitis is a rare adverse event of granulocyte colony-stimulating factor (G-CSF) treatment. Several previous studies have...
Numerous osteoclasts and osteoblasts in the bone marrow due to hyperparathyroidism
Numerous osteoclasts and osteoblasts in the bone marrow due to hyperparathyroidism
Cite this articleFeng, Y., Wang, T. Numerous osteoclasts and osteoblasts in the bone marrow due to hyperparathyroidism. ...
End-of-treatment 18[F]-FDG PET can predict early progression in patients receiving bendamustine-rituximab for follicular lymphoma in first relapse: a prospective West Japan hematology Study Group (W-JHS) NHL01 trial
End-of-treatment 18[F]-FDG PET can predict early progression in patients receiving bendamustine-rituximab for follicular lymphoma in first relapse: a prospective West Japan hematology Study Group (W-JHS) NHL01 trial
Response determined by 18[F]-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)–CT after inductio...
Early hematopoietic cell transplantation for familial hemophagocytic lymphohistiocytosis in a regional treatment network in Japan
Early hematopoietic cell transplantation for familial hemophagocytic lymphohistiocytosis in a regional treatment network in Japan
Familial hemophagocytic lymphohistiocytosis (FHLH) is a fatal hyperinflammation syndrome arising from the genetic defect o...
Incidence trends for common subtypes of T-cell lymphoma in Taiwan and the United States from 2008–2020
Incidence trends for common subtypes of T-cell lymphoma in Taiwan and the United States from 2008–2020
The incidence of T-cell lymphoma (TCL) has been continually increasing in Taiwan and the United States (US) in recent year...
A case of Bloom syndrome manifesting with therapy-related myelodysplastic syndromes harboring a novel BLM gene variant
A case of Bloom syndrome manifesting with therapy-related myelodysplastic syndromes harboring a novel BLM gene variant
Bloom syndrome (BS) is an autosomal recessive genetic disorder caused by variants in the BLM gene. BS is characterized by ...
Isolated salivary gland extramedullary relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia during blinatumomab treatment
Isolated salivary gland extramedullary relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia during blinatumomab treatment
Conflict of interest CI received a research fund, consulting fees, ...
Prognostic model for relapsed/refractory transplant-ineligible diffuse large B-cell lymphoma utilizing the lymphocyte-to-monocyte ratio
Prognostic model for relapsed/refractory transplant-ineligible diffuse large B-cell lymphoma utilizing the lymphocyte-to-monocyte ratio
We conducted a multi-institutional retrospective study in 100 transplant-ineligible (TI) patients with diffuse large B-cel...
Characteristics of chronic lymphocytic leukemia in Japan: Comprehensive analysis of the CLLRSG-01 study
Characteristics of chronic lymphocytic leukemia in Japan: Comprehensive analysis of the CLLRSG-01 study
Chronic lymphocytic leukemia (CLL) is rare in Japan. We conducted the nationwide, prospective observational study CLLRSG-0...
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