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Mathematical modelling of hollow microneedle-mediated transdermal drug delivery
Mathematical modelling of hollow microneedle-mediated transdermal drug delivery
Hollow microneedles represent a promising approach for overcoming the protective barrier of the stratum corneum, facilitat...
Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells
Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells
Exosomes are communication carriers and suitable biomarker candidates due to their cargoes with specific dynamic profiles....
The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E
The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E
The recently deployed RTS,S/AS01E malaria vaccine induces a strong antibody response to the circumsporozoite protein (CSP)...
Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in gastric adenosquamous carcinoma
Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in gastric adenosquamous carcinoma
Primary gastric adenosquamous carcinoma (GASC) is a rare tumor that exhibits aggressive behavior and currently lacks stand...
The prognostic value of the tumor-stroma ratio compared to tumor-infiltrating lymphocytes in triple-negative breast cancer: a review
The prognostic value of the tumor-stroma ratio compared to tumor-infiltrating lymphocytes in triple-negative breast cancer: a review
Previous literature extensively explored biomarkers to personalize treatment for breast cancer patients. The clinical need...
Nodular fasciitis: a case series unveiling novel and rare gene fusions, including two cases with aggressive clinical behavior
Nodular fasciitis: a case series unveiling novel and rare gene fusions, including two cases with aggressive clinical behavior
Nodular fasciitis is a benign myofibroblastic tumor characterized by rapid growth and spontaneous regression. While nodula...
Perforin-2 is overexpressed in Kikuchi-Fujimoto disease
Perforin-2 is overexpressed in Kikuchi-Fujimoto disease
Kikuchi-Fujimoto disease (KFD) is a self-limited lymphadenopathy characterized by subcortical necrosis and paracortical pr...
Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis
Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis
Acute Osteofascial Compartment Syndrome (AOCS) stands as a critical surgical emergency, often secondary to various disease...
Author Correction: Sustained aviremia despite anti-retroviral therapy non-adherence in male children after in utero HIV transmission
These authors contributed equally: Nomonde Bengu, Gabriela Cromhout, Emily Adland.Queen Nandi Regional Hospital, Empangeni...
First-in-human study of epidural spinal cord stimulation in individuals with spinal muscular atrophy
First-in-human study of epidural spinal cord stimulation in individuals with spinal muscular atrophy
Spinal muscular atrophy (SMA) is an inherited neurodegenerative disease causing motoneuron dysfunction, muscle weakness, f...
GPT-4 assistance for improvement of physician performance on patient care tasks: a randomized controlled trial
GPT-4 assistance for improvement of physician performance on patient care tasks: a randomized controlled trial
While large language models (LLMs) have shown promise in diagnostic reasoning, their impact on management reasoning, which...
New neurons are born in the adult human brain
New neurons are born in the adult human brain
Rusty Gage describes how evidence for neurogenesis in the adult human hippocampus shaped our understanding of learning, me...
The MI-CLAIM-GEN checklist for generative artificial intelligence in health
The MI-CLAIM-GEN checklist for generative artificial intelligence in health
The MI-CLAIM checklist has been revised to take account of new capabilities of large language models and other generative ...
When to suspect and how properly early detect and treat patients with endemic mycoses
Update your browser to view ScienceDirect correctly. Your technical details and browser version: Request ID: 90dc6...
Role of CD4+ T cell-derived cytokines in the pathogenesis of uveitis
Role of CD4+ T cell-derived cytokines in the pathogenesis of uveitis
Uveitis refers to a diverse group of inflammatory diseases that affecting the uveal tract, comprising the iris, ciliary bo...
Earth is heating beyond human limits, scientists warn of deadly thresholds
Earth is heating beyond human limits, scientists warn of deadly thresholds
As global temperatures rise, more regions are experiencing heat levels that exceed the human body's ability to cool it...
How olive oil bioactives regulate genes linked to insulin resistance
How olive oil bioactives regulate genes linked to insulin resistance
Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitiv...
Autism risk genes linked to white matter changes at birth, shaping early brain development
Autism risk genes linked to white matter changes at birth, shaping early brain development
Genetic variants linked to autism are associated with structural differences in neonatal white matter, particularly increa...
Parents' role key in shaping children's exposure to mature media
Parents' role key in shaping children's exposure to mature media
As children's screen time continues to rise, so does their exposure to age-inappropriate content, including R-rated mo...
Ethnicity and mental health impact brain health in rural older adults
Ethnicity and mental health impact brain health in rural older adults
A new research paper was published in Aging (Aging-US) on November 27, 2024, in Volume 17, Issue 1, titled "Neurocogn...
Cervical cancer during pregnancy linked to higher maternal health risks
Cervical cancer during pregnancy linked to higher maternal health risks
A new research paper was published in Oncoscience's Volume 12 on January 20, 2025, titled "Maternal, delivery and...
Study explores how nanoplastics could affect child's immune system during pregnancy
Study explores how nanoplastics could affect child's immune system during pregnancy
Allergies and asthma are widespread diseases that could arise during embryonal development in the womb.
Communication between body muscle and pituitary gland may play unexpected role in female fertility
Communication between body muscle and pituitary gland may play unexpected role in female fertility
A newly discovered line of communication between body muscle and the pituitary gland may play an unexpected role in female...
Public health strategies urged to combat early-onset type 2 diabetes in China
Public health strategies urged to combat early-onset type 2 diabetes in China
A new study led by researchers from Peking University, published in Health Data Science, reveals a sharp rise in the burde...
Only a small fraction of people with mental health or substance-use disorders receive effective care
Only a small fraction of people with mental health or substance-use disorders receive effective care
New research estimates that globally, only 6.9 per cent of people with mental health or substance-use disorders receive ef...