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Persistent mutations render cancer cells susceptible to immunotherapy
Persistent mutations render cancer cells susceptible to immunotherapy
Tumor mutation burden is an imperfect predictor of response to immunotherapies. Mutations in regions of the genome unlikel...
Statins beat supplements at cholesterol control
Statins beat supplements at cholesterol control
Six supplements widely marketed as cholesterol-lowering agents performed poorly compared with a low-dose statin — with a s...
Benefits of bariatric surgery prevail
Benefits of bariatric surgery prevail
Despite concerns that bariatric surgery may increase patients’ risk of esophageal or gastric cancers, a large retrospectiv...
Real-world effectiveness of a single dose of mpox vaccine in males
The recent global outbreak of the monkeypox (mpox) virus in humans was declared a public health emergency by the World Hea...
Determinants of COVID-19 vaccination status and hesitancy among older adults in China
Vaccination is the primary defence against SARS-CoV-2, especially among the elderly and those with chronic conditions. Usi...
Seeking therapeutic synergy in BRAF mutant colorectal cancer
Seeking therapeutic synergy in BRAF mutant colorectal cancer
In a phase I trial, the combination of dabrafenib, trametinib and spartalizumab uncovers the crosstalk between the MAPK pa...
Distinct dietary risk factors for incident osteoporotic fractures in early and late postmenopausal phase women
Distinct dietary risk factors for incident osteoporotic fractures in early and late postmenopausal phase women
Available evidence on favorable nutritional factors for preventing osteoporosis remains controversial. Considering the rec...
Cancer–nerve interplay in cancer progression and cancer-induced bone pain
Cancer–nerve interplay in cancer progression and cancer-induced bone pain
Cancer-induced bone pain (CIBP) is one of the most common and debilitating complications associated with bone metastasis. ...
Quantification of Cardiomyocyte Contraction In Vitro and Drug Screening by MyocytoBeats
Quantification of Cardiomyocyte Contraction In Vitro and Drug Screening by MyocytoBeats
Cardiomyocyte contractility is the crucial feature of heart function. Quantifying cardiomyocyte contraction in vitro is es...
Analysis of clinical features and risk factors of peripheral neuropathy in patients with primary Sjögren's syndrome
Analysis of clinical features and risk factors of peripheral neuropathy in patients with primary Sjögren's syndrome
To observe the clinical features and efficacy of immunosuppressive therapy in patients with primary Sjögren's syn...
Clinical spectrum of Chinese hospitalized lung cancer patients with concomitant interstitial lung disease: before and after the new era of LC treatment
Clinical spectrum of Chinese hospitalized lung cancer patients with concomitant interstitial lung disease: before and after the new era of LC treatment
This study aimed to explore the general characteristics and spectrum of hospitalized Chinese patients suffering from lung ...
The safety profile of the first and second monovalent and bivalent BNT162b2 mRNA booster vaccines in older adults
The safety profile of the first and second monovalent and bivalent BNT162b2 mRNA booster vaccines in older adults
Researchers evaluated the safety profiles of booster doses of the monovalent and bivalent mRNA COVID-19 vaccine BNT162b2 i...
Researchers develop a new smartphone-based tool to detect visual impairment in young children
Researchers develop a new smartphone-based tool to detect visual impairment in young children
Researchers conducted a prospective, multicenter, observational study between 14 January 2020 and 30 January 2022 in China.
Study evaluates post-acute sequelae of COVID-19 in US university
Study evaluates post-acute sequelae of COVID-19 in US university
Researchers examined the prevalence and predictors of long coronavirus disease (COVID) in a sample representing a Washingt...
How have home testing kits affected official reporting of COVID-19 cases in the US?
How have home testing kits affected official reporting of COVID-19 cases in the US?
Researchers gathered patient’s patients’ self-reported data about the coronavirus disease 2019 (COVID-19) pandemic from ac...
Study shows how arthritis affects people's working lives
Study shows how arthritis affects people's working lives
The typical person living with arthritis in the UK is 20% less likely to be in work than their equivalent without the cond...
Poll: 13% of Americans aged 50 to 80 show signs of food addiction
Poll: 13% of Americans aged 50 to 80 show signs of food addiction
Whether you call them comfort foods, highly processed foods, junk foods, empty calories or just some of Americans' fav...
Study aims to better understand the effect of spinal cord stimulation on chronic pain and sleep
Study aims to better understand the effect of spinal cord stimulation on chronic pain and sleep
Often debilitating, chronic pain is one of the most common reasons individuals seek medical help. About 65 million adults ...
New research changes the paradigm of how people think about graft-versus-host disease
New research changes the paradigm of how people think about graft-versus-host disease
New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD,...
Young adults with depression and poor mental health more likely to develop cardiovascular disease
Young adults with depression and poor mental health more likely to develop cardiovascular disease
Young adults who feel down or depressed are more likely to develop cardiovascular disease (CVD) and have poor heart health...
Incidence of sports-related sudden cardiac arrest is rare among older adults
Incidence of sports-related sudden cardiac arrest is rare among older adults
The annual incidence of sports-related sudden cardiac arrest in older adults is rare: 2 to 3 cases per 100,000 people.
Using Decision Trees as an Expert System for Clinical Decision Support for COVID-19
Using Decision Trees as an Expert System for Clinical Decision Support for COVID-19
COVID-19 has impacted billions of people and health care systems globally. However, there is currently no publicly availab...
Virchows Archiv (The European Journal of Pathology): Past and future
Virchows Archiv (The European Journal of Pathology): Past and future
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which ...
High-risk HPV-related squamous cell carcinoma in the temporal bone: a rare but noteworthy subtype
High-risk HPV-related squamous cell carcinoma in the temporal bone: a rare but noteworthy subtype
High-risk human papillomavirus (HPV) is a risk factor for the development of several head and neck squamous cell carcinoma...
Zonated quantification of immunohistochemistry in normal and steatotic livers
Zonated quantification of immunohistochemistry in normal and steatotic livers
Immunohistochemical stains (IHC) reveal differences between liver lobule zones in health and disease, including nonalcohol...
Development of intraductal papillary neoplasm of the bile duct in patients with occupational cholangiocarcinoma
Development of intraductal papillary neoplasm of the bile duct in patients with occupational cholangiocarcinoma
This study aimed to investigate the clinicopathological findings of intraductal papillary neoplasm of the bile duct (IPNB)...
Predicting origin for bone metastatic cancer using deep learning-based pathology
eBioMedicineVolume 88, February 2023, 104449Author links open overlay panelMengjieFangabcfZipeiWangcdefJieTianabcDiDongcdP...
Chemotherapy in the afternoon proved to be effective for female lymphoma patients
Chemotherapy in the afternoon proved to be effective for female lymphoma patients
Chemotherapy is a commonly used regimen for cancer treatment, but it is also a double-edged sword. While the drugs are hig...
Treatment to boost white blood cells may benefit patients with glioblastoma
Treatment to boost white blood cells may benefit patients with glioblastoma
A new study led by Washington University School of Medicine in St. Louis reveals at least one cause of low white blood cel...
COVID vaccines and first boosters provided protection to pregnant women during Omicron surge
COVID vaccines and first boosters provided protection to pregnant women during Omicron surge
COVID vaccines and first boosters provided significant protection to pregnant women against severe complications and death...
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