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Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies
Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies
Heart failure with preserved ejection fraction (HFpEF) accounts for more than one-half of total heart failure cases, with ...
Tackling bias in AI health datasets through the STANDING Together initiative
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UKShaswath GanapathiUniversity Hospitals Bi...
Lingering cardiac involvement in previously well people after mild COVID-19
Lingering cardiac involvement in previously well people after mild COVID-19
Serial heart MRI scans conducted in previously well people with mild initial COVID-19 illness suggest that lingering cardi...
Arming T cells against B cells in systemic lupus erythematosus
Arming T cells against B cells in systemic lupus erythematosus
Following a single infusion of CD19-targeting CAR T cells, five patients with SLE showed reduction in disease activity and...
Trogocytosis-mediated tumor relapse after CAR-NK cell therapy prevented by inhibitory CARs
Trogocytosis-mediated tumor relapse after CAR-NK cell therapy prevented by inhibitory CARs
CAR-mediated trogocytosis contributes to dysfunction of natural killer (NK) cells by promoting fratricide and is an import...
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape
Trogocytosis is an active process that transfers surface material from targeted to effector cells. Using multiple in vivo ...
Screening for idiopathic pulmonary fibrosis using comorbidity signatures in electronic health records
Screening for idiopathic pulmonary fibrosis using comorbidity signatures in electronic health records
Idiopathic pulmonary fibrosis (IPF) is a lethal fibrosing interstitial lung disease with a mean survival time of less than...
The top 100 most cited articles in anaphylaxis: a bibliometric analysis
The top 100 most cited articles in anaphylaxis: a bibliometric analysis
Bibliometric analysis is helpful to determine the most influential studies in a specific field. A large number of publicat...
High plasma EBV-DNA load and positive EBER status associated with viral recurrence and persistent infection in early treatment of lymphoma
High plasma EBV-DNA load and positive EBER status associated with viral recurrence and persistent infection in early treatment of lymphoma
The relationship between plasma EBV-DNA load (PEDL) and Epstein–Barr virus (EBV)-encoded small RNA (EBER) during the...
Matrix metalloproteinase 1 is a poor prognostic biomarker for patients with hepatocellular carcinoma
Matrix metalloproteinase 1 is a poor prognostic biomarker for patients with hepatocellular carcinoma
Hepatocellular carcinoma (HCC) remains an incurable malignancy despite the treatment methods being continually updated. Ma...
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis
Osteoporosis (OP) is a systemic metabolic disorder characterized by a reduction in bone tissue volume. LncRNAs have been r...
Establishing a prediction model for recurrence of condyloma acuminatum
Establishing a prediction model for recurrence of condyloma acuminatum
We collected the clinical data of 156 patients diagnosed with condyloma acuminatum (CA), including age, gender, marriage, ...
Diseases, Vol. 10, Pages 69: Communities’ Perception, Knowledge, and Practices Related to Human African Trypanosomiasis in the Democratic Republic of Congo
Diseases, Vol. 10, Pages 69: Communities’ Perception, Knowledge, and Practices Related to Human African Trypanosomiasis in the Democratic Republic of Congo
Background: The number of human African trypanosomiasis (HAT) cases in the Democratic Republic of Congo (DRC) has signific...
Diseases, Vol. 10, Pages 70: The Association of Cytomegalovirus IgM and Allostatic Load
Diseases, Vol. 10, Pages 70: The Association of Cytomegalovirus IgM and Allostatic Load
Background: Cytomegalovirus (CMV) is a deoxyribonucleic acid virus that affects a significant proportion of the worldwide ...
Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model
Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model
Sarcopenia is a complication of Chronic Obstructive Pulmonary Disease (COPD) that negatively affects physical activity and...
Clinical risk factors for severity and prognosis of antiresorptive agent-related osteonecrosis of the jaw: a retrospective observational study
Clinical risk factors for severity and prognosis of antiresorptive agent-related osteonecrosis of the jaw: a retrospective observational study
The incidence of antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is rare, and its management has not yet bee...
Delivery and diffusion of retinal in dermis and epidermis through the combination of prodrug nanoparticles and detachable dissolvable microneedles
Delivery and diffusion of retinal in dermis and epidermis through the combination of prodrug nanoparticles and detachable dissolvable microneedles
To minimize chemical degradation of retinal, we graft this aldehyde on chitosan chains to make them self-assemble into pro...
Enhancement of ketoprofen dissolution rate by the liquisolid technique: optimization and in vitro and in vivo investigations
Enhancement of ketoprofen dissolution rate by the liquisolid technique: optimization and in vitro and in vivo investigations
The objective of the current study is to evaluate the prospective of liquisolid formulation to improve the dissolution rat...
Anticancer and chemosensitization effects of cannabidiol in 2D and 3D cultures of TNBC: involvement of GADD45α, integrin-α5, -β5, -β1, and autophagy
Anticancer and chemosensitization effects of cannabidiol in 2D and 3D cultures of TNBC: involvement of GADD45α, integrin-α5, -β5, -β1, and autophagy
To date, promising therapy for triple negative breast cancer (TNBC) remains a serious concern clinically because of poor p...
Self-assembled polyelectrolyte complexes of chitosan and fucoidan for sustained growth factor release from PRP enhance proliferation and collagen deposition in diabetic mice
Self-assembled polyelectrolyte complexes of chitosan and fucoidan for sustained growth factor release from PRP enhance proliferation and collagen deposition in diabetic mice
Diabetic wound management is a serious health care challenge due to higher rates of relapse, expensive treatment approache...
Nanotherapeutics in autophagy: a paradigm shift in cancer treatment
Nanotherapeutics in autophagy: a paradigm shift in cancer treatment
Autophagy is a catabolic process in which an organism responds to its nutrient or metabolic emergencies. It involves the d...
Correction: Inhalable solid lipid nanoparticles for intracellular tuberculosis infection therapy: macrophage-targeting and pH-sensitive properties
Correction: Inhalable solid lipid nanoparticles for intracellular tuberculosis infection therapy: macrophage-targeting and pH-sensitive properties
Cite this articleMa, C., Wu, M., Ye, W. et al. Correction: Inhalable solid lipid nanoparticles for intracellular tuberculo...
Bioavailability enhancement of vitamin E TPGS liposomes of nintedanib esylate: formulation optimization, cytotoxicity and pharmacokinetic studies
Bioavailability enhancement of vitamin E TPGS liposomes of nintedanib esylate: formulation optimization, cytotoxicity and pharmacokinetic studies
Nintedanib esylate is a kinase inhibitor designated for the cure of non-small cell lung cancer suffered from first-pass me...
A novel method for fabrication of coated microneedles with homogeneous and controllable drug dosage for transdermal drug delivery
A novel method for fabrication of coated microneedles with homogeneous and controllable drug dosage for transdermal drug delivery
Over the years, scientists have been focused on the development of microneedle coating process to coat a broad range of th...
Natural polysaccharide-based biodegradable polymeric platforms for transdermal drug delivery system: a critical analysis
Natural polysaccharide-based biodegradable polymeric platforms for transdermal drug delivery system: a critical analysis
Natural biodegradable polymers generally include polysaccharides (starch, alginate, chitin/chitosan, hyaluronic acid deriv...
Design and optimization of a novel herbosomal-loaded PEG–poloxamer topical formulation for the treatment of cold injuries: a quality-by-design approach
Design and optimization of a novel herbosomal-loaded PEG–poloxamer topical formulation for the treatment of cold injuries: a quality-by-design approach
The spectrum of cold injuries ranges from frostnip, chilblains to severe frostbite. Cold injuries occur upon prolonged exp...
SUMOylation targeting mitophagy in cardiovascular diseases
SUMOylation targeting mitophagy in cardiovascular diseases
Small ubiquitin-like modifier (SUMO) plays a key regulatory role in cardiovascular diseases, such as cardiac hypertrophy, ...
Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression
Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression
Cancer is the second-leading disease-related cause of global mortality after cardiovascular disease. Despite significant a...
The use of biomarkers in the diagnosis and treatment of obstruction of the upper urinary tract in children
Antenatal hydronephrosis, dilatation of the upper urinary tract (UUTD), is a common finding on prenatal ultrasound. One of...
Visual neuroprosthesis: present and future perspectives
The purpose of this study is to provide an overview of the replacements used in lost vision in the form of the bionic eye,...
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