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Association between the Sp1-binding-site polymorphism in the collagen type I alpha 1 (COLIA1) gene and bone phenotypes: the Dubbo Osteoporosis Epidemiology Study
Association between the Sp1-binding-site polymorphism in the collagen type I alpha 1 (COLIA1) gene and bone phenotypes: the Dubbo Osteoporosis Epidemiology Study
Polymorphisms within the collagen 1 alpha 1 gene (COLIA1) have been shown to be associated with bone mineral density (BMD)...
Influence of disease activity and gonadal status on bone mineral density and turnover in acromegaly
Influence of disease activity and gonadal status on bone mineral density and turnover in acromegaly
The purpose of this study was to evaluate the impact of disease activity and gonadal status on bone mineral density (BMD) ...
Nationwide database study of postoperative sequelae and in-hospital mortality in super-elderly hip fracture patients
Nationwide database study of postoperative sequelae and in-hospital mortality in super-elderly hip fracture patients
The risk of postoperative sequelae and in-hospital mortality in Japanese patients aged 90 years and older with hi...
Aromatase inhibitors, bone microstructure, and estimated bone strength in postmenopausal women with breast cancer: a 5-year prospective study
Aromatase inhibitors, bone microstructure, and estimated bone strength in postmenopausal women with breast cancer: a 5-year prospective study
Aromatase inhibitors (AIs) are the standard treatment for early breast cancer (EBC) and are typical causative agents of ca...
Meclozine and growth hormone ameliorate bone length and quality in experimental models of achondroplasia
Meclozine and growth hormone ameliorate bone length and quality in experimental models of achondroplasia
Achondroplasia (ACH) is a common skeletal dysplasia associated with short-limbed short stature caused by gain-of-function ...
Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
Disulfiram (DSF), known as an anti-alcoholism drug, has been reported to suppress osteoclast differentiation in vitro; how...
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Chemotherapy-induced bone loss (CTIBL) is common among breast cancer patients, requiring comprehensive assessment and inte...
Accelerated bone loss in late reproductive-aged and perimenopausal women with vitamin D insufficiency
Accelerated bone loss in late reproductive-aged and perimenopausal women with vitamin D insufficiency
The association between serum vitamin D levels and bone mineral density (BMD) varies by race and gender. This study aimed ...
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7
Hedgehog and canonical Wnt signaling pathways and the transcription factors Runx2 and Sp7 are essential for osteoblast dif...
Gender differences between smoking and the risk of hip fracture
Gender differences between smoking and the risk of hip fracture
This study aimed to estimate the relation between cigarette smoking and hip fracture in men compared with women using a me...
Real-life effects of pharmacological osteoporosis treatments on bone mineral density by quantitative computed tomography
Real-life effects of pharmacological osteoporosis treatments on bone mineral density by quantitative computed tomography
Monitoring of bone mineral density (BMD) is used to assess pharmacological osteoporosis therapy. This study examined the r...
Wnt family members regulating osteogenesis and their origins
Wnt family members regulating osteogenesis and their origins
Wnt signaling plays an important role in the regulation of bone metabolism. Wnt activates the β-catenin-mediated cano...
Temporal declines in bone mineral density and trabecular bone score during androgen deprivation therapy
Temporal declines in bone mineral density and trabecular bone score during androgen deprivation therapy
The trabecular bone score (TBS) has emerged as a convenient measure for assessing the microstructure of trabecular bone in...
Updated reference values for BMD and lean mass measured by DXA in Thai children
Updated reference values for BMD and lean mass measured by DXA in Thai children
This study established normative references for total body less head (TBLH) BMD, lumbar spine (L1–L4) BMD, and both ...
Correction: Crosstalk between bone and the immune system
Correction: Crosstalk between bone and the immune system
Mechanism of bone destruction in RA. The intricate immune–bone interaction among lymphocytes, fibroblasts, osteoclasts and...
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Heterotopic ossification of the tendon and ligament (HOTL) is a chronic progressive disease that is usually accompanied by...
Diagnostic accuracy of chest X-ray and CT using artificial intelligence for osteoporosis: systematic review and meta-analysis
Diagnostic accuracy of chest X-ray and CT using artificial intelligence for osteoporosis: systematic review and meta-analysis
Artificial intelligence (AI)-based systems using chest images are potentially reliable for diagnosing osteoporosis. We per...
Olink and gut microbial metabolomics reveal new biomarkers for the prediction and diagnosis of PMOP
Olink and gut microbial metabolomics reveal new biomarkers for the prediction and diagnosis of PMOP
Postmenopausal osteoporosis (PMOP) can cause postmenopausal women to experience pain and interference. Identifying and exp...
Effect of bisphosphonate and denosumab treatment on TBS in Japanese breast cancer patients with AIBL
Effect of bisphosphonate and denosumab treatment on TBS in Japanese breast cancer patients with AIBL
Bisphosphonates and denosumab increase bone mineral density (BMD) for osteoporosis treatment in patients with aromatase in...
Association of physical activity and sitting time with femoral bone health among older cancer survivors
Association of physical activity and sitting time with femoral bone health among older cancer survivors
Our primary goal was to investigate the independent and combined associations of physical activity (PA) and sitting time (...
Senso-immunology: the hidden relationship between sensory system and immune system
Senso-immunology: the hidden relationship between sensory system and immune system
The primary sensory neurons involved in pain perception express various types of receptor-type ion channels at their nerve...
Crosstalk between bone and the immune system
Crosstalk between bone and the immune system
Bone functions not only as a critical element of the musculoskeletal system but also serves as the primary lymphoid organ ...
Crosstalk between kidney and bone: insights from CKD-MBD
Crosstalk between kidney and bone: insights from CKD-MBD
The kidneys play an important role in the regulation of phosphate and calcium balance and serum concentrations, coordinate...
Correction: Effect of CBX7 deficiency on the socket healing after tooth extractions
Correction: Effect of CBX7 deficiency on the socket healing after tooth extractions
Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, No. 140, Hanzhong Road, Nanjing, 210029, People’s Rep...
The predictive value of albumin to alkaline phosphatase ratio for vertebral refractures in postmenopausal women
The predictive value of albumin to alkaline phosphatase ratio for vertebral refractures in postmenopausal women
To investigate the clinical value of serum albumin to alkaline phosphatase ratio (AAPR) in predicting the risk of osteopor...
Bone: the largest organ in the multi-organ network
Bone: the largest organ in the multi-organ network
Fine and intricate tuning of the crosstalk between multiple organs is a fundamental p...
Correction: Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study
Correction: Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study
Adjusted hazard ratio for incident vertebral fracture according to baseline values. ucOC undercarboxylated osteocalcin, BA...
Chemotherapy effects on bone mineral density and microstructure in women with breast cancer
Chemotherapy effects on bone mineral density and microstructure in women with breast cancer
Chemotherapy involves the administration of steroids to prevent nausea and vomiting; however, its effect on bone microstru...
Incidence of four major osteoporotic fragility fractures among older individuals in Sado, Japan, in 2020
Incidence of four major osteoporotic fragility fractures among older individuals in Sado, Japan, in 2020
This study compared the 2020 incidence of fragility fractures in Sado City with those from 2004 to 2015. Data from patient...
Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
We aimed to comprehensively compile placebo-controlled trials on the efficacy and safety of romosozumab (210 mg, ...
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