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Insights into skeletal involvement in adult Gaucher disease: a single-center experience
Insights into skeletal involvement in adult Gaucher disease: a single-center experience
Gaucher disease (GD) is a lysosomal storage disorder causing systemic and skeletal complications. This study evaluates bon...
Associations between bone material strength index and FRAX scores
Associations between bone material strength index and FRAX scores
Impact microindentation (IMI) measures bone material strength index (BMSi) in vivo. However, its ability to predict fractu...
Correlation between serum high-density lipoprotein cholesterol and bone mineral density in vitamin D-deficient populations
Correlation between serum high-density lipoprotein cholesterol and bone mineral density in vitamin D-deficient populations
To investigate the relationship between serum high-density lipoprotein (HDL) cholesterol and bone mineral density (BMD) in...
Prevalence of vertebral fractures at death
Prevalence of vertebral fractures at death
Despite many studies on the prevalence of vertebral fractures (VFs), the VF prevalence at death in the Japanese population...
Osteoporosis and stroke: a bidirectional mendelian randomization study
Osteoporosis and stroke: a bidirectional mendelian randomization study
Numerous observational studies have identified a link between osteoporosis and stroke. However, the causal genetic relatio...
Thoracolumbar kyphosis prognoses poor results after proximal femoral fracture: a 3-year multicenter prospective cohort study
Thoracolumbar kyphosis prognoses poor results after proximal femoral fracture: a 3-year multicenter prospective cohort study
Proximal femoral fractures are critically associated with increased risk of mortality and secondary fractures. Identifying...
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis
Osteoarthritis (OA) is a chronic degenerative joint disorder characterized by an imbalance in chondrocyte metabolism. Ferr...
Osteoporosis screening using X-ray assessment and osteoporosis self-assessment tool for Asians in hip surgery patients
Osteoporosis screening using X-ray assessment and osteoporosis self-assessment tool for Asians in hip surgery patients
As many patients with osteoporosis remain undiagnosed, we aimed to develop a simple method to efficiently screen for osteo...
Multiple thyroid disorders and risk of osteoporosis: a two-sample Mendelian randomization study
Multiple thyroid disorders and risk of osteoporosis: a two-sample Mendelian randomization study
Previous research has demonstrated that even minor changes in thyroid function are associated with an increased risk of os...
Histological assessments for anabolic effects in teriparatide/abaloparatide administered rodent models
Histological assessments for anabolic effects in teriparatide/abaloparatide administered rodent models
Parathyroid hormone (PTH) is thought to induce remodeling-based bone formation by promoting osteoclastic activity, a proce...
Nutrient foramina of human fibula: morphometric analysis and clinical relevance
Nutrient foramina of human fibula: morphometric analysis and clinical relevance
The fibula, situated laterally in the leg, receives vital nutrition through nutrient arteries during embryonic bone growth...
Association between the Sp1-binding-site polymorphism in the collagen type I alpha 1 (COLIA1) gene and bone phenotypes: the Dubbo Osteoporosis Epidemiology Study
Association between the Sp1-binding-site polymorphism in the collagen type I alpha 1 (COLIA1) gene and bone phenotypes: the Dubbo Osteoporosis Epidemiology Study
Polymorphisms within the collagen 1 alpha 1 gene (COLIA1) have been shown to be associated with bone mineral density (BMD)...
Influence of disease activity and gonadal status on bone mineral density and turnover in acromegaly
Influence of disease activity and gonadal status on bone mineral density and turnover in acromegaly
The purpose of this study was to evaluate the impact of disease activity and gonadal status on bone mineral density (BMD) ...
Nationwide database study of postoperative sequelae and in-hospital mortality in super-elderly hip fracture patients
Nationwide database study of postoperative sequelae and in-hospital mortality in super-elderly hip fracture patients
The risk of postoperative sequelae and in-hospital mortality in Japanese patients aged 90 years and older with hi...
Aromatase inhibitors, bone microstructure, and estimated bone strength in postmenopausal women with breast cancer: a 5-year prospective study
Aromatase inhibitors, bone microstructure, and estimated bone strength in postmenopausal women with breast cancer: a 5-year prospective study
Aromatase inhibitors (AIs) are the standard treatment for early breast cancer (EBC) and are typical causative agents of ca...
Meclozine and growth hormone ameliorate bone length and quality in experimental models of achondroplasia
Meclozine and growth hormone ameliorate bone length and quality in experimental models of achondroplasia
Achondroplasia (ACH) is a common skeletal dysplasia associated with short-limbed short stature caused by gain-of-function ...
Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
Disulfiram (DSF), known as an anti-alcoholism drug, has been reported to suppress osteoclast differentiation in vitro; how...
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Chemotherapy-induced bone loss (CTIBL) is common among breast cancer patients, requiring comprehensive assessment and inte...
Accelerated bone loss in late reproductive-aged and perimenopausal women with vitamin D insufficiency
Accelerated bone loss in late reproductive-aged and perimenopausal women with vitamin D insufficiency
The association between serum vitamin D levels and bone mineral density (BMD) varies by race and gender. This study aimed ...
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7
Hedgehog and canonical Wnt signaling pathways and the transcription factors Runx2 and Sp7 are essential for osteoblast dif...
Gender differences between smoking and the risk of hip fracture
Gender differences between smoking and the risk of hip fracture
This study aimed to estimate the relation between cigarette smoking and hip fracture in men compared with women using a me...
Real-life effects of pharmacological osteoporosis treatments on bone mineral density by quantitative computed tomography
Real-life effects of pharmacological osteoporosis treatments on bone mineral density by quantitative computed tomography
Monitoring of bone mineral density (BMD) is used to assess pharmacological osteoporosis therapy. This study examined the r...
Wnt family members regulating osteogenesis and their origins
Wnt family members regulating osteogenesis and their origins
Wnt signaling plays an important role in the regulation of bone metabolism. Wnt activates the β-catenin-mediated cano...
Temporal declines in bone mineral density and trabecular bone score during androgen deprivation therapy
Temporal declines in bone mineral density and trabecular bone score during androgen deprivation therapy
The trabecular bone score (TBS) has emerged as a convenient measure for assessing the microstructure of trabecular bone in...
Updated reference values for BMD and lean mass measured by DXA in Thai children
Updated reference values for BMD and lean mass measured by DXA in Thai children
This study established normative references for total body less head (TBLH) BMD, lumbar spine (L1–L4) BMD, and both ...
Correction: Crosstalk between bone and the immune system
Correction: Crosstalk between bone and the immune system
Mechanism of bone destruction in RA. The intricate immune–bone interaction among lymphocytes, fibroblasts, osteoclasts and...
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Heterotopic ossification of the tendon and ligament (HOTL) is a chronic progressive disease that is usually accompanied by...
Diagnostic accuracy of chest X-ray and CT using artificial intelligence for osteoporosis: systematic review and meta-analysis
Diagnostic accuracy of chest X-ray and CT using artificial intelligence for osteoporosis: systematic review and meta-analysis
Artificial intelligence (AI)-based systems using chest images are potentially reliable for diagnosing osteoporosis. We per...
Olink and gut microbial metabolomics reveal new biomarkers for the prediction and diagnosis of PMOP
Olink and gut microbial metabolomics reveal new biomarkers for the prediction and diagnosis of PMOP
Postmenopausal osteoporosis (PMOP) can cause postmenopausal women to experience pain and interference. Identifying and exp...
Effect of bisphosphonate and denosumab treatment on TBS in Japanese breast cancer patients with AIBL
Effect of bisphosphonate and denosumab treatment on TBS in Japanese breast cancer patients with AIBL
Bisphosphonates and denosumab increase bone mineral density (BMD) for osteoporosis treatment in patients with aromatase in...
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