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Locomotor Brachii Sign in Aortic Regurgitation
Locomotor Brachii Sign in Aortic Regurgitation
Images in Clinical Medicine from The New England Journal of Medicine — Locomotor Brachii Sign in Aortic Regurgitation
VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19
VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19
Abstract Background Nirmatrelvir–ritonavir has been authorized for emergency use by many countries for the treatment of co...
Acute Decompensated Heart Failure, Volume, and Acetazolamide
Acute Decompensated Heart Failure, Volume, and Acetazolamide
To the Editor: The report on the Acetazolamide in Decompensated Heart Failure with Volume Overload (ADVOR) trial by Mullen...
Daprodustat and On-Treatment Cardiovascular Events in Chronic Kidney Disease
Daprodustat and On-Treatment Cardiovascular Events in Chronic Kidney Disease
To the Editor: Hypoxia-inducible factor (HIF) stabilizers are approved to treat anemia of chronic kidney disease in differ...
Alcohol-Associated Hepatitis
Alcohol-Associated Hepatitis
Alcohol-Associated Hepatitis The authors review the epidemiology, pathophysiology, and treatment of alcohol-associated hep...
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort
A Man with Exertional Chest Discomfort A 38-year-old man with no cardiac risk factors was evaluated because of episodic ch...
A Brewing Storm
A Brewing Storm
A Brewing Storm This interactive feature describes a 68-year-old woman with a 2-year history of intermittent palpitations ...
Nirmatrelvir Use during the Omicron Surge
Nirmatrelvir Use during the Omicron Surge
To the Editor: Arbel et al. (Sept. 1 issue)1 found that among adults 65 years of age or older, the rates of hospitalizatio...
A Sense of Belonging
A Sense of Belonging
A Sense of Belonging In this documentary video, Anita Blanchard, a Black female physician, reflects on experiences in medi...
Haloperidol for Treatment of ICU Delirium — Progress or Setback?
Haloperidol for Treatment of ICU Delirium — Progress or Setback?
Delirium is common, morbid, and costly in hospitalized older adults and in adults of all ages in the intensive care unit (...
Choice of Admitting Services for Older Adults with Hip Fracture
Choice of Admitting Services for Older Adults with Hip Fracture
Older Adults with Hip Fracture This feature about an older adult patient with a fragility fracture offers a case vignette ...
Drug Sensitivity of Currently Circulating Mpox Viruses
Drug Sensitivity of Currently Circulating Mpox Viruses
Drug Sensitivity of Mpox Isolates from 12 patients with mpox virus infection showed in vitro sensitivity at clinically ach...
Engineering for Grief
Engineering for Grief
Engineering for Grief After his mother’s death, a physician wondered how his father, a human process engineer who’d always...
Hospitals and Health Equity — Translating Measurement into Action
Hospitals and Health Equity — Translating Measurement into Action
Hospitals and Health Equity Implementation of health-equity measures focused on health-related social needs by CMS is an i...
Pulmonary Langerhans-Cell Histiocytosis
Pulmonary Langerhans-Cell Histiocytosis
Images in Clinical Medicine from The New England Journal of Medicine — Pulmonary Langerhans-Cell Histiocytosis
Neutralization against BA.2.75.2, BQ.1.1, and XBB from mRNA Bivalent Booster
Neutralization against BA.2.75.2, BQ.1.1, and XBB from mRNA Bivalent Booster
Omicron Neutralization after Bivalent Vaccine Boost One or two monovalent vaccine boosters showed a large decrease in neut...
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C
Abstract Background Adagrasib, an oral small-molecule inhibitor of mutant KRAS G12C protein, has shown clinical activity i...
Protecting the Public Health with the Inflation Reduction Act — Provisions Affecting Climate Change and Its Health Effects
Protecting the Public Health with the Inflation Reduction Act — Provisions Affecting Climate Change and Its Health Effects
Public Health and the Inflation Reduction Act The Inflation Reduction Act, the most significant measure adopted by Congres...
Protection against Omicron from Vaccination and Previous Infection
Protection against Omicron from Vaccination and Previous Infection
To the Editor: Chin et al. (Nov. 10 issue)1 report the effectiveness of messenger RNA vaccination and previous SARS-CoV-2 ...
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer
Abstract Background KRAS p.G12C mutation occurs in approximately 1 to 2% of pancreatic cancers. The safety and efficacy of...
Recombinant ADAMTS13 for Hereditary Thrombotic Thrombocytopenic Purpura
Recombinant ADAMTS13 for Hereditary Thrombotic Thrombocytopenic Purpura
Summary A 27-year-old patient with a history of severe obstetrical complications and arterial thrombosis received a diagno...
Biologics in Eosinophilic Esophagitis — Ready for Prime Time?
Biologics in Eosinophilic Esophagitis — Ready for Prime Time?
Eosinophilic esophagitis is an immune-mediated, chronic, inflammatory disease of the esophagus that was first recognized a...
Case 39-2022: A 31-Year-Old Woman with Postpartum Abdominal Pain and Fever
Case 39-2022: A 31-Year-Old Woman with Postpartum Abdominal Pain and Fever
A Woman with Postpartum Abdominal Pain and Fever A 31-year-old woman was admitted 15 days after the birth of her child bec...
Surgical Revascularization — Best for Limb Ischemia?
Surgical Revascularization — Best for Limb Ischemia?
In 2015, approximately 237 million people worldwide had been diagnosed with peripheral arterial disease, an increase of 17...
Two Steps Forward, One Step Back
Two Steps Forward, One Step Back
Tuberculosis is an important cause of death worldwide, and drug resistance is implicated in one third of the almost 2 mill...
A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis
A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis
Abstract Background In patients with rifampin-resistant tuberculosis, all-oral treatment regimens that are more effective,...
Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis
Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis
Abstract Background Dupilumab, a fully human monoclonal antibody, blocks interleukin-4 and interleukin-13 signaling, which...
Lentiviral Gene Therapy for Artemis-Deficient SCID
Lentiviral Gene Therapy for Artemis-Deficient SCID
Abstract Background The DNA-repair enzyme Artemis is essential for rearrangement of T- and B-cell receptors. Mutations in ...
Monkeypox Virus Infection across 16 Countries — April–June 2022
Monkeypox Virus Infection across 16 Countries — April–June 2022
To the Editor: According to Thornhill et al. (Aug. 25 issue),1 semen was positive for monkeypox (recently renamed mpox) vi...
Audio Interview: Potential Covid Vaccine Strategies
Audio Interview: Potential Covid Vaccine Strategies
Potential Covid Vaccine Strategies In this audio interview conducted on December 20, 2022, the editors discuss evolving Co...
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