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The patient’s voice: a cross-sectional study of physical health and disability in juvenile idiopathic arthritis
The patient’s voice: a cross-sectional study of physical health and disability in juvenile idiopathic arthritis
With increasing focus on patient-reported outcome measures (PROMs) in chronic rheumatic diseases, we aimed to evaluate the...
Type I interferon biomarker in idiopathic inflammatory myopathies: associations of Siglec-1 with disease activity and treatment response
Type I interferon biomarker in idiopathic inflammatory myopathies: associations of Siglec-1 with disease activity and treatment response
AbstractObjectives. Novel biomarkers are needed to guide therapy in idiopathic inflammatory myopathies (IIM). Expression o...
The emergence of SLE-causing UNC93B1 variants in 2024
During the past year, four studies have reported ten mutations in UNC93B1, which encodes the Toll-like receptor (TLR) chap...
Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development
Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development
Materials and methodsPatients and normal volunteersThis study was approved by the Biomedical Ethics Committee of Anhui Med...
New WHO ACPA standard enables standardisation among anti-CCP2 assays, but not other ACPA assays using different antigens
New WHO ACPA standard enables standardisation among anti-CCP2 assays, but not other ACPA assays using different antigens
Antibodies to citrullinated protein/peptide (ACPA) are established biomarkers for diagnosis and classification of rheumato...
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
IntroductionRheumatoid arthritis (RA) is a chronic inflammatory joint disease that affects up to 1% of the population.1 Th...
SerpinA3N limits cartilage destruction in osteoarthritis by inhibiting macrophage-derived leucocyte elastase
SerpinA3N limits cartilage destruction in osteoarthritis by inhibiting macrophage-derived leucocyte elastase
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Rheumatoid arthritis patients harbour aberrant enteric bacteriophages with autoimmunity-provoking potential: a paired sibling study
Rheumatoid arthritis patients harbour aberrant enteric bacteriophages with autoimmunity-provoking potential: a paired sibling study
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Multiorgan involvement and circulating IgG1 predict hypocomplementaemia in IgG4-related disease
Multiorgan involvement and circulating IgG1 predict hypocomplementaemia in IgG4-related disease
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EULAR/PReS recommendations for the diagnosis and management of Stills disease, comprising systemic juvenile idiopathic arthritis and adult-onset Stills disease
EULAR/PReS recommendations for the diagnosis and management of Stills disease, comprising systemic juvenile idiopathic arthritis and adult-onset Stills disease
Overarching principles OP A: sJIA and AOSD are the same disease, that should be designated by the same unique name, Still...
Development of international consensus on a standardised image acquisition protocol for diagnostic evaluation of the sacroiliac joints by MRI: an ASAS-SPARTAN collaboration
Development of international consensus on a standardised image acquisition protocol for diagnostic evaluation of the sacroiliac joints by MRI: an ASAS-SPARTAN collaboration
IntroductionFor several decades, MRI has been used to investigate the early diagnosis of inflammatory sacroiliitis.1 2 How...
Clinical information on imaging referrals for suspected or known axial spondyloarthritis: recommendations from the Assessment of Spondyloarthritis International Society (ASAS)
Clinical information on imaging referrals for suspected or known axial spondyloarthritis: recommendations from the Assessment of Spondyloarthritis International Society (ASAS)
IntroductionImaging plays a pivotal role in the diagnosis and ongoing management of axial spondyloarthritis (axSpA), a con...
Early identification of rheumatoid arthritis: does it induce treatment-related cost savings?
Early identification of rheumatoid arthritis: does it induce treatment-related cost savings?
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New onset work disability in rheumatoid arthritis is an underrecognized cardiovascular risk factor: A retrospective cohort study using the CorEvitas registry
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Novel biomarkers in RA: Implication for diagnosis, prognosis, and personalised treatment
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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis
Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis
Gout is a progressive form of arthritis that causes significant pain and disability. Patients with treatment-refractory (o...
Musculoskeletal ultrasound characteristics of checkpoint inhibitor-associated inflammatory arthritis
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Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis refractory to biologic therapy: 2-year clinical and radiographic results from the open-label extension of the SELECT-AXIS 2 study
Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis refractory to biologic therapy: 2-year clinical and radiographic results from the open-label extension of the SELECT-AXIS 2 study
The efficacy and safety of upadacitinib in patients with ankylosing spondylitis (AS) and inadequate response/intolerance t...
Publisher Correction: Recent advances in the diagnosis and management of neuropsychiatric lupus
Authors and AffiliationsDivision of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Heal...
Séraphin (1747-1800), “the facetious hunchback”: How ankylosing spondylitis contributed to the success of his shadow puppet theatre
Séraphin (1747-1800), “the facetious hunchback”: How ankylosing spondylitis contributed to the success of his shadow puppet theatre
Séraphin (1747–1800) is considered the founder of shadow puppetry in France. This “facetious hunchback...
Finding the Role of Anifrolumab in the New Paradigm of Systemic Lupus Erythematosus Treatment
Finding the Role of Anifrolumab in the New Paradigm of Systemic Lupus Erythematosus Treatment
The article by Tani et al, “Anifrolumab in Refractory Systemic Lupus Erythematosus: A Real-World, Multicenter Study,”1 eva...
Analysis of Gout Remission Definitions in a Randomized Controlled Trial of Colchicine Prophylaxis for People With Gout Initiating Allopurinol
Analysis of Gout Remission Definitions in a Randomized Controlled Trial of Colchicine Prophylaxis for People With Gout Initiating Allopurinol
Analysis of Gout Remission Definitions in a Randomized Controlled Trial of Colchicine Prophylaxis for P...
Intravenous Golimumab in Children With Polyarticular-Course Juvenile Idiopathic Arthritis: Long-Term Extension of an Open-Label Phase III Study
Intravenous Golimumab in Children With Polyarticular-Course Juvenile Idiopathic Arthritis: Long-Term Extension of an Open-Label Phase III Study
AbstractObjective To report pharmacokinetics (PK), immunogenicity, clinical effect, and safety of intravenous (IV) golimum...
Scleroderma Renal Crisis: Clues From the Physical Exam
Scleroderma Renal Crisis: Clues From the Physical Exam
Scleroderma renal crisis (SRC) is a rare, life-threatening complication of systemic sclerosis (SSc) and can sometimes be t...
Treatment with tofacitinib attenuates muscle loss through myogenin activation in the collagen-induced arthritis
Treatment with tofacitinib attenuates muscle loss through myogenin activation in the collagen-induced arthritis
Sarcopenia is a muscle disease characterized by reduction of muscle strength and muscle mass. In RA, 25.9 to 43.3% of the ...
Investigation of GPM6B as a novel therapeutic target in Osteoarthritis
Investigation of GPM6B as a novel therapeutic target in Osteoarthritis
Osteoarthritis (OA) is the most common motor system disease in older people, characterized by a high incidence and signifi...
Clinical practice pattern of Pneumocystis pneumonia prophylaxis in systemic lupus erythematosus: a cross-sectional study from lupus registry of nationwide institutions (LUNA)
Clinical practice pattern of Pneumocystis pneumonia prophylaxis in systemic lupus erythematosus: a cross-sectional study from lupus registry of nationwide institutions (LUNA)
Pneumocystis jirovecii pneumonia (PCP) is an opportunistic infection in patients undergoing immunosuppressive therapy, suc...
Small heterodimer partner-interacting leucine zipper protein suppresses pain and cartilage destruction in an osteoarthritis model by modulating the AMPK/STAT3 signaling pathway
Small heterodimer partner-interacting leucine zipper protein suppresses pain and cartilage destruction in an osteoarthritis model by modulating the AMPK/STAT3 signaling pathway
Osteoarthritis (OA) is a degenerative joint disease caused by the breakdown of joint cartilage and adjacent bone. Joint in...
Guselkumab in Biologic-Naïve Patients with Active Psoriatic Arthritis in Russia: A Post Hoc Analysis of the DISCOVER-1 and -2 Randomized Clinical Trials
Guselkumab in Biologic-Naïve Patients with Active Psoriatic Arthritis in Russia: A Post Hoc Analysis of the DISCOVER-1 and -2 Randomized Clinical Trials
There are limited data on the use of advanced therapies to treat psoriatic arthritis (PsA) in Russia. Guselkumab, an inter...
Efficacy and Safety of Tofacitinib in Patients with Psoriatic Arthritis or Ankylosing Spondylitis by Cigarette Smoking Status
Efficacy and Safety of Tofacitinib in Patients with Psoriatic Arthritis or Ankylosing Spondylitis by Cigarette Smoking Status
Routine care studies of psoriatic arthritis (PsA) and ankylosing spondylitis (AS) demonstrated attenuated responses to tum...
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