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Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model
Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model
To characterize aspects of triiodothyronine (T3) induced chondrocyte terminal maturation within the molecular osteoarthrit...
Current perspective on infections and mitigation strategies in primary systemic vasculitis
Current perspective on infections and mitigation strategies in primary systemic vasculitis
The purpose of this review is to summarize and evaluate most recent evidence on the epidemiology of infections and associa...
Elevating the Standard of Care for Patients with Psoriatic Arthritis: ‘Calls to Action’ from a Multistakeholder Pan-European Initiative
Elevating the Standard of Care for Patients with Psoriatic Arthritis: ‘Calls to Action’ from a Multistakeholder Pan-European Initiative
Psoriatic arthritis (PsA) is a complex, progressive, and often debilitating disease. Despite recent advances in treatment,...
Population Pharmacokinetics of the Anti-Interferon-Gamma Monoclonal Antibody Emapalumab: An Updated Analysis
Population Pharmacokinetics of the Anti-Interferon-Gamma Monoclonal Antibody Emapalumab: An Updated Analysis
Emapalumab is a fully human monoclonal antibody that targets free and receptor-bound interferon-gamma (IFNγ), neutral...
Elevating the Standard of Care for Patients with Axial Spondyloarthritis: ‘Calls to Action’ from Rheumacensus, a Multistakeholder Pan-European Initiative
Elevating the Standard of Care for Patients with Axial Spondyloarthritis: ‘Calls to Action’ from Rheumacensus, a Multistakeholder Pan-European Initiative
Several barriers to optimal care in axial spondyloarthritis (axSpA) exist, which is detrimental to patient outcomes. The R...
A Phase 1a Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7303509, an Anti-TGFβ3 Antibody, in Healthy Volunteers
A Phase 1a Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7303509, an Anti-TGFβ3 Antibody, in Healthy Volunteers
Transforming growth factor beta (TGFβ) cytokines (TGFβ1, TGFβ2, and TGFβ3) play critical roles in tiss...
Major cardiovascular events in patients with cardiovascular monosodium urate deposits in atherosclerotic plaques
Major cardiovascular events in patients with cardiovascular monosodium urate deposits in atherosclerotic plaques
AbstractObjective. To determine the association of cardiovascular atherosclerotic plaque monosodium urate deposits with th...
Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial
Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial
AbstractObjective. We explored the efficacy and safety of brentuximab vedotin, a chimeric anti-CD30 antibody drug conjugat...
Positivity in serum MMP-3 after clinical remission or low disease activity at 52 weeks leads to future joint destruction in patients with rheumatoid arthritis
Positivity in serum MMP-3 after clinical remission or low disease activity at 52 weeks leads to future joint destruction in patients with rheumatoid arthritis
medRxiv - The Preprint Server for Health Sciences
Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation
Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation
medRxiv - The Preprint Server for Health Sciences
Corrigendum to “A randomized trial of a motivational interviewing intervention to increase lifestyle physical activity and improve self-reported function in adults with arthritis” [Seminars in Arthritis and Rheumatism 47(2018): 732–740]
Corrigendum to “A randomized trial of a motivational interviewing intervention to increase lifestyle physical activity and improve self-reported function in adults with arthritis” [Seminars in Arthritis and Rheumatism 47(2018): 732–740]
Volume 66, June 2024, 152451Author links open overlay panelAbigail L. Gilbert a, Jungwha Lee b c, Linda Ehrlich-Jones c d ...
Serum urate change among gout patients treated with sodium-glucose cotransporter type 2 inhibitors vs. sulfonylurea: A comparative effectiveness analysis
Serum urate change among gout patients treated with sodium-glucose cotransporter type 2 inhibitors vs. sulfonylurea: A comparative effectiveness analysis
Gout is the most common inflammatory arthritis with a substantial and rising global disease burden [1]. This ‘modern gout ...
Antiphospholipid Patients Admitted in the Intensive Care Unit: What Must The Rheumatologist Know?
Antiphospholipid Patients Admitted in the Intensive Care Unit: What Must The Rheumatologist Know?
Antiphospholipid syndrome (APS) is a rare systemic autoimmune disorder that can escalate into a 'thrombotic storm'...
Bone health and physical activity in adolescents with juvenile idiopathic arthritis: a cross-sectional case-control study
Bone health and physical activity in adolescents with juvenile idiopathic arthritis: a cross-sectional case-control study
Adolescents with juvenile idiopathic arthritis (JIA) tend to engage in less physical activity than their typically develop...
Myofascial pain – A major player in musculoskeletal pain
Myofascial pain – A major player in musculoskeletal pain
Available online 21 April 2024, 101944Author links open overlay panel, , , , , AbstractMyofascial pain is a soft tissue pa...
Risk perception, well-being, depression and anxiety in children and adolescents with rheumatic diseases during the COVID-19 pandemic - results from the prospective multicenter KICK-COVID study in Germany
Risk perception, well-being, depression and anxiety in children and adolescents with rheumatic diseases during the COVID-19 pandemic - results from the prospective multicenter KICK-COVID study in Germany
To investigate the psychosocial burden in children and adolescents with juvenile rheumatic diseases during the COVID-19 pa...
Assessment of enthesopathy in conventional pelvis radiography: Another tool for spondyloarthritis diagnosis beyond sacroiliitis
Assessment of enthesopathy in conventional pelvis radiography: Another tool for spondyloarthritis diagnosis beyond sacroiliitis
Introduction/objectivesEnthesitis is a cardinal feature of spondylarthritis (SpA), and the pelvis is a common site of enth...
Osteoarthritis and hypertension: observational and Mendelian randomization analyses
Osteoarthritis and hypertension: observational and Mendelian randomization analyses
The association between osteoarthritis (OA) and hypertension is a subject of ongoing debate in observational research, and...
Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study
Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study
We aimed to reveal the effect of abatacept (ABT) on atherosclerosis in rheumatoid arthritis (RA) patients, 3-year efficacy...
Exploring the Effects of Ixekizumab on Pain in Patients with Ankylosing Spondylitis Based on Objective Measures of Inflammation: Post Hoc Analysis from a Large Randomized Clinical Trial
Exploring the Effects of Ixekizumab on Pain in Patients with Ankylosing Spondylitis Based on Objective Measures of Inflammation: Post Hoc Analysis from a Large Randomized Clinical Trial
The objective of this analysis is to evaluate the improvement in spinal pain with ixekizumab, placebo, and adalimumab base...
A Machine Learning Approach for Prediction of CDAI Remission with TNF Inhibitors: A Concept of Precision Medicine from the FIRST Registry
A Machine Learning Approach for Prediction of CDAI Remission with TNF Inhibitors: A Concept of Precision Medicine from the FIRST Registry
This study aimed to develop low-cost models using machine learning approaches predicting the achievement of Clinical Disea...
Hemophagocytic lymphohistiocytosis and macrophage activation syndrome: two rare sides of the same devastating coin
Hemophagocytic lymphohistiocytosis and macrophage activation syndrome: two rare sides of the same devastating coin
Hemophagocytic lymphohistiocytosis (HLH) is a rare genetic hyperinflammatory syndrome that occurs early in life. Macrophag...
Efficacy and Safety of Secukinumab in US Patients with Psoriatic Arthritis: A Subgroup Analysis of the Phase 3 FUTURE Studies
Efficacy and Safety of Secukinumab in US Patients with Psoriatic Arthritis: A Subgroup Analysis of the Phase 3 FUTURE Studies
The aim of this work is to evaluate secukinumab vs. placebo in a challenging-to-treat and smaller US patient subpopulation...
Plasmin Cleavage of Beta-2-Glycoprotein I Alters its Structure and Ability to Bind to Pathogenic Antibodies
Plasmin Cleavage of Beta-2-Glycoprotein I Alters its Structure and Ability to Bind to Pathogenic Antibodies
medRxiv - The Preprint Server for Health Sciences
Prevalence and impact of foot peripheral neuropathy in Systemic Sclerosis (SSc): results from a single centre cross-sectional study.
Prevalence and impact of foot peripheral neuropathy in Systemic Sclerosis (SSc): results from a single centre cross-sectional study.
medRxiv - The Preprint Server for Health Sciences
Prevalence of spondyloarthritis in inflammatory bowel disease according ASAS and ultrassonography and its correlation with plasma calprotectin
Prevalence of spondyloarthritis in inflammatory bowel disease according ASAS and ultrassonography and its correlation with plasma calprotectin
Enteropathic spondyloarthritis is underdiagnosed and inflammatory biomarkers and ultrasonography (US) could be useful for ...
Drug survival and change of disease activity using a second janus kinase inhibitor in patients with difficult-to-treat rheumatoid arthritis who failed to a janus kinase inhibitor and subsequent biologics
Drug survival and change of disease activity using a second janus kinase inhibitor in patients with difficult-to-treat rheumatoid arthritis who failed to a janus kinase inhibitor and subsequent biologics
To assess the drug survival and change of disease activity using a second Janus kinase inhibitor (JAKi) after failure to a...
Unveiling the clinical spectrum of relapsing polychondritis: insights into its pathogenesis, novel monogenic causes, and therapeutic strategies
Unveiling the clinical spectrum of relapsing polychondritis: insights into its pathogenesis, novel monogenic causes, and therapeutic strategies
Relapsing polychondritis is a rare multisystem disease involving cartilaginous and proteoglycan-rich structures. The diagn...
Prognostic and functional importance of both overt and subclinical left ventricular systolic dysfunction in systemic sclerosis
Prognostic and functional importance of both overt and subclinical left ventricular systolic dysfunction in systemic sclerosis
MethodsAustralian Scleroderma Cohort Study participants meeting ACR/EULAR criteria for SSc with ≥1 echocardiographic LVEF ...
Potential therapeutic targets of fibrosis in inflammatory rheumatic diseases
Potential therapeutic targets of fibrosis in inflammatory rheumatic diseases
Fibrosis is recognized as pathogenic tissue remodeling, which is involved in a variety of diseases. This process is attrib...
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