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Hemophagocytic lymphohistiocytosis and macrophage activation syndrome: two rare sides of the same devastating coin
Hemophagocytic lymphohistiocytosis and macrophage activation syndrome: two rare sides of the same devastating coin
Hemophagocytic lymphohistiocytosis (HLH) is a rare genetic hyperinflammatory syndrome that occurs early in life. Macrophag...
Efficacy and Safety of Secukinumab in US Patients with Psoriatic Arthritis: A Subgroup Analysis of the Phase 3 FUTURE Studies
Efficacy and Safety of Secukinumab in US Patients with Psoriatic Arthritis: A Subgroup Analysis of the Phase 3 FUTURE Studies
The aim of this work is to evaluate secukinumab vs. placebo in a challenging-to-treat and smaller US patient subpopulation...
Prognostic and functional importance of both overt and subclinical left ventricular systolic dysfunction in systemic sclerosis
Prognostic and functional importance of both overt and subclinical left ventricular systolic dysfunction in systemic sclerosis
MethodsAustralian Scleroderma Cohort Study participants meeting ACR/EULAR criteria for SSc with ≥1 echocardiographic LVEF ...
Potential therapeutic targets of fibrosis in inflammatory rheumatic diseases
Potential therapeutic targets of fibrosis in inflammatory rheumatic diseases
Fibrosis is recognized as pathogenic tissue remodeling, which is involved in a variety of diseases. This process is attrib...
Response to kollas. Letter to the editor, “problems with opioids beyond misuse”
Response to kollas. Letter to the editor, “problems with opioids beyond misuse”
Available online 14 April 2024, 101946Author links open overlay panel, , , Section snippetsDeclaration of interestDr Clauw...
Integrative analysis of single-cell and bulk transcriptome data reveal the significant role of macrophages in lupus nephritis
Integrative analysis of single-cell and bulk transcriptome data reveal the significant role of macrophages in lupus nephritis
We attempted to identify abnormal immune cell components and signaling pathways in lupus nephritis (LN) and to identify po...
Deregulation in adult IgA vasculitis skin as the basis for the discovery of novel serum biomarkers
Deregulation in adult IgA vasculitis skin as the basis for the discovery of novel serum biomarkers
Immunoglobulin A vasculitis (IgAV) in adults has a variable disease course, with patients often developing gastrointestina...
Advancing precision rheumatology through tissue and blood profiling
Advancing precision rheumatology through tissue and blood profiling
Multidimensional and single-cell profiling of peripheral blood and inflamed tissues is a powerful and high-resolution tool...
Problems with “Problems with opioids beyond misuse”
Problems with “Problems with opioids beyond misuse”
Available online 10 April 2024, 101947Author links open overlay panel, , Section snippetsDeclaration of interestsThe autho...
Deep Learning Enables Automatic Detection of Joint Damage Progression in Rheumatoid Arthritis—Model Development and External Validation
Deep Learning Enables Automatic Detection of Joint Damage Progression in Rheumatoid Arthritis—Model Development and External Validation
AbstractObjectives. Although deep learning has demonstrated substantial potential in automatic quantification of joint dam...
Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis
Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis
In rheumatoid arthritis, juvenile idiopathic arthritis and other forms of inflammatory arthritis, the immune system target...
Molecular biomarker approaches to prevention of post-traumatic osteoarthritis
Molecular biomarker approaches to prevention of post-traumatic osteoarthritis
Up to 50% of individuals develop post-traumatic osteoarthritis (PTOA) within 10 years following knee-joint injuries such a...
Shift in perspective: autoimmunity protecting against rheumatoid arthritis
Shift in perspective: autoimmunity protecting against rheumatoid arthritis
A hallmark of rheumatoid arthritis (RA) is the increased levels of autoantibodies preceding the onset and contributing to ...
Comorbidity clusters in patients with rheumatoid arthritis identify a patient phenotype with a favourable prognosis
Comorbidity clusters in patients with rheumatoid arthritis identify a patient phenotype with a favourable prognosis
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EPO promotes the progression of rheumatoid arthritis by inducing desialylation via increasing the expression of neuraminidase 3
EPO promotes the progression of rheumatoid arthritis by inducing desialylation via increasing the expression of neuraminidase 3
WHAT IS ALREADY KNOWN ON THIS TOPICAnaemia occurs in 30%–70% of patients with rheumatoid arthritis (RA), which leads to th...
Goodbye to the term 'ankylosing spondylitis, hello 'axial spondyloarthritis: time to embrace the ASAS-defined nomenclature
Goodbye to the term 'ankylosing spondylitis, hello 'axial spondyloarthritis: time to embrace the ASAS-defined nomenclature
Ankylosing spondylitis (AS) is the historic term used for decades for the HLA-B27-associated inflammatory disease affectin...
Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-{alpha} in rheumatoid arthritis
Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-{alpha} in rheumatoid arthritis
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Single-cell profiling reveals kidney CD163+ dendritic cell participation in human lupus nephritis
Single-cell profiling reveals kidney CD163+ dendritic cell participation in human lupus nephritis
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