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Impairment of White Matter Microstructure and Structural Network in Patients with Systemic Lupus Erythematosus
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The history of ankylosing spondylitis/axial spondyloarthritis – what is the driving force of new knowledge ?
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Established and novel insights to guide cancer assessment in patients with idiopathic inflammatory myopathies
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Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage
Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage
Osteoarthritis (OA) is a painful degenerative joint disease and a leading source of years lived with disability globally d...
Comparing immunogenicity and safety following transition from reference rituximab to biosimilar rituximab (DRL_RI) in patients with rheumatoid arthritis: a randomized, double-blind, phase 3 study
Comparing immunogenicity and safety following transition from reference rituximab to biosimilar rituximab (DRL_RI) in patients with rheumatoid arthritis: a randomized, double-blind, phase 3 study
To assess immunogenicity and safety in patients with active rheumatoid arthritis (RA) transitioning from rituximab [US-lic...
Novel multiple Z-score models for detection of coronary artery dilation: application in Kawasaki disease
Novel multiple Z-score models for detection of coronary artery dilation: application in Kawasaki disease
This study aims to develop Z-Score models to normalize measurements of three coronary arteries and enhance the diagnosis o...
Abatacept for myositis
In a phase III clinical trial of abatacept for idiopathic inflammatory myopathy, the primary endpoint was not met but the ...
European expert recommendations for managing systemic sclerosis and its complications
The updated 2023 EULAR recommendations for treatment of systemic sclerosis bring notable changes to recommendations for sk...
Clinical Features, Outcomes of Treatments, Inflammasome Function and Longitudinal Clonal Dynamics into NLRP3 Mosaicism: Evidence from the Largest Cryopyrin-associated Periodic Syndromes Cohort to Date
Clinical Features, Outcomes of Treatments, Inflammasome Function and Longitudinal Clonal Dynamics into NLRP3 Mosaicism: Evidence from the Largest Cryopyrin-associated Periodic Syndromes Cohort to Date
medRxiv - The Preprint Server for Health Sciences
Prevalence of comorbidities and cardiovascular risk factor management in hand osteoarthritis: a cross-sectional study
Prevalence of comorbidities and cardiovascular risk factor management in hand osteoarthritis: a cross-sectional study
To assess the prevalence of comorbidities and management of cardiovascular risk factors according to established guideline...
Value of ultrasound-assessed dactylitis in the early diagnosis of psoriatic arthritis
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Defining cause of death in a contemporary cohort with ANCA-associated vasculitis (AAV): a comparison of electronic health record and death certificate data
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The effect of biological treatment on female fertility: a cohort study of women with rheumatoid arthritis and psoriatic arthritis
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The operational definition of old age and impact on outcomes in DMARD-treated patients with rheumatoid arthritis: A systematic literature review
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KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus
KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus
Neutropenia is more common in patients with systemic lupus erythematosus (SLE) and is a major cause of life-threatening in...
Quantitative 18F-FDG PET-CT can assess presence and extent of interstitial lung disease in early severe diffuse cutaneous systemic sclerosis
Quantitative 18F-FDG PET-CT can assess presence and extent of interstitial lung disease in early severe diffuse cutaneous systemic sclerosis
This study aimed to assess the quantitative uptake of 18F-FDG PET-CT in the lungs of patients with early severe diffuse cu...
Neutrophil extracellular traps and oxidative stress in systemic lupus erythematosus patients with and without renal involvement
Neutrophil extracellular traps and oxidative stress in systemic lupus erythematosus patients with and without renal involvement
To investigate the levels of plasma neutrophil extracellular traps (NETs) and free thiols, the latter reflecting systemic ...
Efficacy and safety of tofacitinib in an open-label, long-term extension study in patients with psoriatic arthritis who received adalimumab or tofacitinib in a Phase 3 randomized controlled study: a post hoc analysis
Efficacy and safety of tofacitinib in an open-label, long-term extension study in patients with psoriatic arthritis who received adalimumab or tofacitinib in a Phase 3 randomized controlled study: a post hoc analysis
Data on treatment switching directly from tumor necrosis factor inhibitors to tofacitinib in psoriatic arthritis (PsA) are...
A non-invasive model for diagnosis of primary Sjogren’s disease based on salivary biomarkers, serum autoantibodies, and Schirmer’s test
A non-invasive model for diagnosis of primary Sjogren’s disease based on salivary biomarkers, serum autoantibodies, and Schirmer’s test
Minor salivary gland (MSG) biopsy is a critical but invasive method for the classification of primary Sjögren’s...
Synovial dendritic cell subsets in RA
Synovial dendritic cell profiles and localization patterns provide insights about the roles of dendritic cell subsets in t...
Blocking CDK7 attenuates inflammatory arthritis
In a new study, inhibition of CDK7 disrupted the RNA polymerase II transcription cycle, leading to anti-inflammatory effec...
Insights into IVDD pathogenesis in 2024
Emerging research in intervertebral disc degeneration in 2024 highlights microbial, immune and inflammatory mechanisms tha...
Molecular profiling for advancing precision rheumatology
Molecular profiling for advancing precision rheumatology
Here, we highlight three publications in 2024 that have advanced the field of molecular and immunological profiling, for&a...
Successful rituximab treatment in a seronegative rheumatoid arthritis patient with concurrent cold agglutinin syndrome and immune thrombocytopenia
Successful rituximab treatment in a seronegative rheumatoid arthritis patient with concurrent cold agglutinin syndrome and immune thrombocytopenia
Cold agglutinin disease, a subtype of cold-type autoimmune hemolytic anemia, is referred to as cold agglutinin syndrome (C...
Pulmonary involvement in newly diagnosed and untreated rheumatoid arthritis and psoriatic arthritis: a prospective longitudinal study
Pulmonary involvement in newly diagnosed and untreated rheumatoid arthritis and psoriatic arthritis: a prospective longitudinal study
To longitudinally assesses pulmonary involvement in newly diagnosed rheumatoid arthritis (RA) and psoriatic arthritis (PsA...
New onset heart failure in adolescents with inflammatory joint disease treated with TNF-α inhibitors: a case-based review
New onset heart failure in adolescents with inflammatory joint disease treated with TNF-α inhibitors: a case-based review
The safety of tumor necrosis factor (TNF) inhibitors has been demonstrated for over two decades. However, their effects on...
Fibromyalgia comorbidity in Systemic Lupus Erythematosus patients: assessing impact on quality of life
Fibromyalgia comorbidity in Systemic Lupus Erythematosus patients: assessing impact on quality of life
The prevalence of Fibromyalgia in patients with Systemic Lupus Erythematosus (SLE) is significantly higher compared to the...
Hck promotes IL-1β-induced extracellular matrix degradation, inflammation, and apoptosis in osteoarthritis via activation of the JAK-STAT3 signaling pathway
Hck promotes IL-1β-induced extracellular matrix degradation, inflammation, and apoptosis in osteoarthritis via activation of the JAK-STAT3 signaling pathway
We investigated role of haematopoietic cell kinase (Hck) in osteoarthritis (OA) and to explore the underlying mechanisms d...
Investigating the causal relationship between immune factors and ankylosing spondylitis: insights from a Mendelian Randomization study
Investigating the causal relationship between immune factors and ankylosing spondylitis: insights from a Mendelian Randomization study
Despite previous studies indicating a close relationship between immune system and ankylosing spondylitis (AS), the causal...
Integrated safety analysis of tofacitinib from Phase 2 and 3 trials of patients with ankylosing spondylitis
Integrated safety analysis of tofacitinib from Phase 2 and 3 trials of patients with ankylosing spondylitis
Describe tofacitinib safety from an integrated analysis of randomized controlled trials (RCTs) in patients with ankylosing...
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