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Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort
Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort
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Identifying the association between serum urate levels and gout flares in patients taking urate-lowering therapy: a post hoc cohort analysis of the CARES trial with consideration of dropout
Identifying the association between serum urate levels and gout flares in patients taking urate-lowering therapy: a post hoc cohort analysis of the CARES trial with consideration of dropout
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Exploring the effect on primary endpoints in trials testing targeted therapy interventions for rheumatoid arthritis: a meta-epidemiological study on the appropriate use of a core outcome set
Exploring the effect on primary endpoints in trials testing targeted therapy interventions for rheumatoid arthritis: a meta-epidemiological study on the appropriate use of a core outcome set
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Efficacy and safety of targeted therapies in VEXAS syndrome: retrospective study from the FRENVEX
Efficacy and safety of targeted therapies in VEXAS syndrome: retrospective study from the FRENVEX
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Efficacy and safety of first-line biological DMARDs in rheumatoid arthritis patients with chronic kidney disease
Efficacy and safety of first-line biological DMARDs in rheumatoid arthritis patients with chronic kidney disease
IntroductionChronic kidney disease (CKD) is notably more prevalent in patients with rheumatoid arthritis (RA) than in the ...
CD8+ tissue-resident memory T cells are expanded in primary Sjögrens disease and can be therapeutically targeted by CD103 blockade
CD8+ tissue-resident memory T cells are expanded in primary Sjögrens disease and can be therapeutically targeted by CD103 blockade
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Correspondence on 'EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update by Hellmich et al
Correspondence on 'EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update by Hellmich et al
Shared decision-making (SDM) is a collaborative approach to disease management whereby patients and clinicians discuss the...
Response to: Correspondence on 'EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update by Hellmich et al
Response to: Correspondence on 'EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update by Hellmich et al
We wish to thank Robson et al for emphasising the role of shared decision-making between healthcare providers and patients...
Inflammatory tissue priming: novel insights and therapeutic opportunities for inflammatory rheumatic diseases
Inflammatory tissue priming: novel insights and therapeutic opportunities for inflammatory rheumatic diseases
Due to optimised treatment strategies and the availability of new therapies during the last decades, formerly devastating ...
Predictors for severe persisting pain in rheumatoid arthritis are associated with pain origin and appraisal of pain
Predictors for severe persisting pain in rheumatoid arthritis are associated with pain origin and appraisal of pain
WHAT IS ALREADY KNOWN ON THIS TOPICPain is a cardinal symptom of inflammatory arthritis and represents a critical paramete...
Vascular disease persistence in giant cell arteritis: are stromal cells neglected?
Vascular disease persistence in giant cell arteritis: are stromal cells neglected?
IntroductionGiant cell arteritis (GCA), an age-related inflammatory disease of large and medium-sized arteries, predilects...
Integrated safety analysis of filgotinib in patients with moderate-to-severe rheumatoid arthritis over a treatment duration of up to 8.3 years
Integrated safety analysis of filgotinib in patients with moderate-to-severe rheumatoid arthritis over a treatment duration of up to 8.3 years
IntroductionRheumatoid arthritis (RA) is a persistent inflammatory condition with no cure; patients rely on long-term trea...
NAT10 promotes synovial aggression by increasing the stability and translation of N4-acetylated PTX3 mRNA in rheumatoid arthritis
NAT10 promotes synovial aggression by increasing the stability and translation of N4-acetylated PTX3 mRNA in rheumatoid arthritis
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Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events
IntroductionApproximately 30% of patients with systemic lupus erythematosus (SLE) harbour antiphospholipid antibodies (aPL...
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis
IntroductionFibrosis describes the accumulation of extracellular matrix in tissues and organs. Although short-term fibroge...
Correspondence on 'Long COVID: a new word for naming fibromyalgia? by Mariette
Correspondence on 'Long COVID: a new word for naming fibromyalgia? by Mariette
I read the Viewpoint on long-COVID by Mariette with interest and consent.1 Mariette, skilled experimental and clinical imm...
Acute rheumatic fever in the province of Manitoba, Canada, before and after the coronavirus (COVID-19) pandemic
Acute rheumatic fever in the province of Manitoba, Canada, before and after the coronavirus (COVID-19) pandemic
The COVID-19 pandemic came with strict public health guidelines for social distancing and infection control measures. Scho...
Disease activity drives divergent epigenetic and transcriptomic reprogramming of monocyte subpopulations in systemic lupus erythematosus
Disease activity drives divergent epigenetic and transcriptomic reprogramming of monocyte subpopulations in systemic lupus erythematosus
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Nasal tophi
Nasal tophi
A 39-year-old man presented at our hospital due to recurrent swelling, redness and pain in his nasal area over the past 2 ...
Sacroiliac radiographic progression over 10 years in axSpA: data from the DESIR inception cohort
Sacroiliac radiographic progression over 10 years in axSpA: data from the DESIR inception cohort
WHAT IS ALREADY KNOWN ON THIS TOPICInformation about the likelihood of radiographic sacroiliitis over time in patients wit...
Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker
Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker
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Retraction: PKC{delta} null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth
Retraction: PKC{delta} null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth
Kc R, Li X, Kroin JS, et al. PKCδ null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independentl...
Annals of the Rheumatic Diseases collection on epigenetics: from three dimensional chromatin organisation to microRNA
Annals of the Rheumatic Diseases collection on epigenetics: from three dimensional chromatin organisation to microRNA
IntroductionThe term ‘epigenetics’ describes various mechanisms that in their entirety control the gene expression of a ce...
Current myositis clinical trials and tribulations
Current myositis clinical trials and tribulations
With improved understanding of disease pathogenesis and availability of outcome measures, there has been a remarkable incr...
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special?
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special?
Rheumatoid arthritis (RA) exhibits common characteristics with numerous other autoimmune diseases, including the presence ...
The role of DNA in the pathogenesis of SLE: DNA as a molecular chameleon
The role of DNA in the pathogenesis of SLE: DNA as a molecular chameleon
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by antibodies to DNA (anti-DNA) and ot...
Gender equity in global rheumatology awards
Gender equity in global rheumatology awards
Globally, there has been a growing interest in addressing gender disparities in leadership positions within rheumatology,1...
Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study
Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study
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KLF2 enhancer variant rs4808485 increases lupus risk by modulating inflammasome machinery and cellular homoeostasis
KLF2 enhancer variant rs4808485 increases lupus risk by modulating inflammasome machinery and cellular homoeostasis
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Response to: Correspondence on 'Long COVID: a new word for naming fibromyalgia?" by Mariette
Response to: Correspondence on 'Long COVID: a new word for naming fibromyalgia?" by Mariette
I thank Robert Landewe1 for his interest and consent regarding my viewpoint on the resemblance between ‘long COVID’ and fi...
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