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ICTV Virus Taxonomy Profile: Fusariviridae 2024
ICTV Virus Taxonomy Profile: Fusariviridae 2024
Fusariviridae is a family of mono-segmented, positive-sense RNA viruses with genome sizes of 5.9–10.7 kb. Most genomic RNA...
Molecular and biological characterization of a bunyavirus infecting the brown planthopper (Nilaparvata lugens)
Molecular and biological characterization of a bunyavirus infecting the brown planthopper (Nilaparvata lugens)
A negative-strand symbiotic RNA virus, tentatively named Nilaparvata lugens Bunyavirus (NLBV), was identified in the brown...
ICTV Virus Taxonomy Profile: Hantaviridae 2024
ICTV Virus Taxonomy Profile: Hantaviridae 2024
Hantaviridae is a family for negative-sense RNA viruses with genomes of about 10.5–14.6 kb. These viruses are maintained i...
Translational arrest and mRNA decay are independent activities of alphaherpesvirus virion host shutoff proteins
Translational arrest and mRNA decay are independent activities of alphaherpesvirus virion host shutoff proteins
The herpes simplex virus 1 (HSV1) virion host shutoff (vhs) protein is an endoribonuclease that regulates the translationa...
Cardiac glycosides inhibit early and late vaccinia virus protein expression
Cardiac glycosides inhibit early and late vaccinia virus protein expression
Cardiac glycosides (CGs) are natural steroid glycosides, which act as inhibitors of the cellular sodium-potassium ATPase p...
Acute Rift Valley fever virus infection induces inflammatory cytokines and cell death in ex vivo rat brain slice culture
Acute Rift Valley fever virus infection induces inflammatory cytokines and cell death in ex vivo rat brain slice culture
Rift Valley fever virus (RVFV) is an emerging arboviral disease with pandemic potential. While infection is often self-lim...
Crystal structure of the ATPase domain of porcine circovirus type 2 Rep protein
Crystal structure of the ATPase domain of porcine circovirus type 2 Rep protein
PCV2 belongs to the genus Circovirus in the family Circoviridae, whose genome is replicated by rolling circle replication ...
Oxidative stress governs mosquito innate immune signalling to reduce chikungunya virus infection in Aedes-derived cells
Oxidative stress governs mosquito innate immune signalling to reduce chikungunya virus infection in Aedes-derived cells
Arboviruses such as chikungunya, dengue and zika viruses cause debilitating diseases in humans. The principal vector speci...
Licorice extract inhibits porcine epidemic diarrhea virus in vitro and in vivo
Licorice extract inhibits porcine epidemic diarrhea virus in vitro and in vivo
Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea and even death in piglets, resulting in significant economic...
Downregulation of endogenous nectin1 in human keratinocytes by herpes simplex virus 1 glycoprotein D excludes superinfection but does not affect NK cell function
Downregulation of endogenous nectin1 in human keratinocytes by herpes simplex virus 1 glycoprotein D excludes superinfection but does not affect NK cell function
Many viruses downregulate their cognate receptors, facilitating virus replication and pathogenesis via processes that are ...
The plant virus transmissions database
The plant virus transmissions database
Plant viruses are transmitted mechanically or by vegetative propagation, and by vectors such as arthropods, fungi, nematod...
Structural basis for nuclear import of bat adeno-associated virus capsid protein
Structural basis for nuclear import of bat adeno-associated virus capsid protein
Adeno-associated viruses (AAV) are one of the world’s most promising gene therapy vectors and as a result, are one of the ...
Forty-nine metagenomic-assembled genomes from an aquatic virome expand Caudoviricetes by 45 potential new families and the newly uncovered Gossevirus of Bamfordvirae
Forty-nine metagenomic-assembled genomes from an aquatic virome expand Caudoviricetes by 45 potential new families and the newly uncovered Gossevirus of Bamfordvirae
Twenty complete genomes (29–63 kb) and 29 genomes with an estimated completeness of over 90 % (30–90 kb) were identified f...
Incidental finding of a human-like tusavirus in a lamb with lip lesions and fatal pneumonia
Incidental finding of a human-like tusavirus in a lamb with lip lesions and fatal pneumonia
Tusaviruses in the genus Protoparvovirus of family Parvoviridae were first identified in a diarrhoeic Tunisian child in 20...
ICTV Virus Taxonomy Profile: Kolmioviridae 2024
ICTV Virus Taxonomy Profile: Kolmioviridae 2024
Kolmioviridae is a family for negative-sense RNA viruses with circular, viroid-like genomes of about 1.5–1.7 kb that are m...
Immunogenicity, safety and duration of protection afforded by chikungunya virus vaccines undergoing human clinical trials
Immunogenicity, safety and duration of protection afforded by chikungunya virus vaccines undergoing human clinical trials
Background. Chikungunya virus (CHIKV) causes chikungunya fever and has been responsible for major global epidemics of arth...
Evolutionary analysis and biological characterization of a novel alphabaculovirus isolated from Mythimna separata
Evolutionary analysis and biological characterization of a novel alphabaculovirus isolated from Mythimna separata
Baculoviruses are insect-specific pathogens. Novel baculovirus isolates provide new options for the biological control of ...
Newcastle disease virus regulates its replication by instigating oxidative stress-driven Sirtuin 7 production
Newcastle disease virus regulates its replication by instigating oxidative stress-driven Sirtuin 7 production
Reactive oxygen species (ROS) accumulation inside the cells instigates oxidative stress, activating stress-responsive gene...
Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model
Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model
Infections with persistent or latent viruses alter host immune homeostasis and have potential to affect the outcome of con...
Virus-host coevolutionary analyses of an Alphabaculovirus with a wide host range
Virus-host coevolutionary analyses of an Alphabaculovirus with a wide host range
Baculoviruses are highly host specific, and their host range is usually restricted to a single or a few closely related in...
ICTV Virus Taxonomy Profile: Filoviridae 2024
ICTV Virus Taxonomy Profile: Filoviridae 2024
Filoviridae is a family of negative-sense RNA viruses with genomes of about 13.1–20.9 kb that infect fish, mammals and rep...
A conserved methyltransferase active site residue of Zika virus NS5 is required for the restriction of STING activation and interferon expression
A conserved methyltransferase active site residue of Zika virus NS5 is required for the restriction of STING activation and interferon expression
Zika virus (ZIKV) is a re-emerging RNA virus and causes major public health events due to its link to severe neurological ...
Transmission dynamics and pathogenesis differ between pheasants and partridges infected with clade 2.3.4.4b H5N8 and H5N1 high-pathogenicity avian influenza viruses
Transmission dynamics and pathogenesis differ between pheasants and partridges infected with clade 2.3.4.4b H5N8 and H5N1 high-pathogenicity avian influenza viruses
During the UK 2020–2021 epizootic of H5Nx clade 2.3.4.4b high-pathogenicity avian influenza viruses (HPAIVs), high mortali...
Elucidating the biological characteristics and pathogenicity of the highly virulent G2a porcine epidemic diarrhea virus
Elucidating the biological characteristics and pathogenicity of the highly virulent G2a porcine epidemic diarrhea virus
Since the large-scale outbreak of porcine epidemic diarrhoea (PED) in 2010, caused by the genotype 2 (G2) variant of the p...
Indirect CD4+ T cell protection against persistent MCMV infection by NK cells requires IFNγ
Indirect CD4+ T cell protection against persistent MCMV infection by NK cells requires IFNγ
Host control of mouse cytomegalovirus (MCMV) infection of MHCII- salivary gland acinar cells is mediated by CD4+ T cells, ...
Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein
Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein
The COVID-19 pandemic has highlighted the need for vaccines capable of providing rapid and robust protection. One way to i...
Structural and functional characterization of siadenovirus core protein VII nuclear localization demonstrates the existence of multiple nuclear transport pathways
Structural and functional characterization of siadenovirus core protein VII nuclear localization demonstrates the existence of multiple nuclear transport pathways
Adenovirus protein VII (pVII) plays a crucial role in the nuclear localization of genomic DNA following viral infection an...
Sporadic cases of chronic wasting disease in old moose – an epidemiological study
Sporadic cases of chronic wasting disease in old moose – an epidemiological study
Transmissible spongiform encephalopathies or prion diseases comprise diseases with different levels of contagiousness unde...
Mapping respiratory syncytial virus fusion protein interactions with the receptor IGF1R and the impact of alanine-scanning mutagenesis on viral infection
Mapping respiratory syncytial virus fusion protein interactions with the receptor IGF1R and the impact of alanine-scanning mutagenesis on viral infection
Respiratory syncytial virus (RSV) has two main surface glycoproteins, the attachment glycoprotein (G) and the fusion (F) p...
WIV, a protein domain found in a wide number of arthropod viruses, which probably facilitates infection
WIV, a protein domain found in a wide number of arthropod viruses, which probably facilitates infection
The most powerful approach to detect distant homologues of a protein is based on structure prediction and comparison. Yet ...
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