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Design, synthesis, and structure−activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
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More than just DNA damage: Pt(ΙΙ)-NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death
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Structure–activity relationship studies of Imidazo[1′,2′:1,6]pyrido[2,3-d]pyrimidine derivatives to develop selective FGFR inhibitors as anticancer agents for FGF19-overexpressed hepatocellular carcinoma
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Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold
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Proceedings of the 4th International Civil Engineering and Architecture Conference
Proceedings of the 4th International Civil Engineering and Architecture Conference
This book provides an overview of the ongoing transformation of the AEC industry in the fields of green building design, c...
Nanomaterials exert biological effects by influencing the ubiquitin-proteasome system
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Advances in the synthesis and engineering of conotoxins
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Discovery of phenazine derivatives as a new class of non-classical ferroptosis inhibitors and efficacy evaluation on a mouse model of liver injury
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Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-l-rhamnosidase: Design, synthesis and structure-activity relationship study
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Optimisation of a novel series of ENaC inhibitors, leading to the selection of the long-acting inhaled clinical candidate ETD001, a potential new treatment for cystic fibrosis
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Design, synthesis and anti-tumor evaluation of novel pyrimidine and quinazoline analogues
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Allosteric inhibition of PTP1B by bromocatechol-chalcone derivatives
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Synthesis, evaluation and mechanism study of novel pyrazole enamides to alleviate lung injury
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α-GalCer sp2-iminoglycolipid analogs as CD1d-dependent iNKT modulators: Evaluation of their immunotherapeutic potential in murine models of asthma and autoimmune hepatitis
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Impact of the hydrophilic-lipophilic balance of free-base and Zn(II) tricationic pyridiniumporphyrins and irradiation wavelength in PDT against the melanoma cell lines
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Fenofibrate as an Adjunct Therapy for Ulcerative Colitis: Targeting Inflammation via SIRT1, NLRP3, and AMPK Pathways: A Randomized Controlled Pilot Study
Fenofibrate as an Adjunct Therapy for Ulcerative Colitis: Targeting Inflammation via SIRT1, NLRP3, and AMPK Pathways: A Randomized Controlled Pilot Study
We assess the effects of fenofibrate as an adjunct therapy for mild-moderate UC and investigate its underlying mechanistic...
Comparative Analysis of Hemodynamic Effects of Remimazolam and Propofol Combined with Esketamine in Colonoscopic Procedures in the Elderly
Comparative Analysis of Hemodynamic Effects of Remimazolam and Propofol Combined with Esketamine in Colonoscopic Procedures in the Elderly
Clarifying effects of remimazolam and esketamine vs. propofol and esketamine on hemodynamic parameters in elderly patients...
Safety and Effectiveness of Naltrexone-Bupropion in Korean Adults with Obesity: Post-Marketing Surveillance Study
Safety and Effectiveness of Naltrexone-Bupropion in Korean Adults with Obesity: Post-Marketing Surveillance Study
Investigating the safety and effectiveness of naltrexone-bupropion in Korean adults with obesity.
Aqueous Extract of Rhubarb Promotes Hepatotoxicity via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer [Letter]
Aqueous Extract of Rhubarb Promotes Hepatotoxicity via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer [Letter]
Letter for the article Aqueous Extract of Rhubarb Promotes Hepatotoxicity via Facilitating PKM2-Mediated Aerobic Glycolysi...
Evaluating the Efficacy of Oral Ivermectin on Clinical Symptoms and Demodex Densities in Patients with Demodicosis
Evaluating the Efficacy of Oral Ivermectin on Clinical Symptoms and Demodex Densities in Patients with Demodicosis
This study aims to evaluate the effectiveness of oral ivermectin on clinical symptoms and Dds of patients with demodicosis.
Inhibition of SARS-CoV-2 replication in cells by G-quadruplex ligands
Inhibition of SARS-CoV-2 replication in cells by G-quadruplex ligands
The coronavirus SARS-CoV-2 continues to spread worldwide. Dozens of compounds have been discovered based on the structure ...
Evaluation of cholinesterase enzyme inhibitory potential of dipterocarpol derivatives
Evaluation of cholinesterase enzyme inhibitory potential of dipterocarpol derivatives
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) - are depression and neurodegenerative diseases that target e...
Review: Chemical and biological features of genus Paralemnalia soft corals
Review: Chemical and biological features of genus Paralemnalia soft corals
Marine soft corals are plentiful sources of a wide range of natural products. They include an extensive array of chemical ...
Thiophene ring-opening reactions. Part VII: synthesis and antitumor, anti-inflammatory, and antioxidant properties of 1,3,4‒thiadiazoline‒6-sulfanylthiopyran-4(1H)-one hybrids
Thiophene ring-opening reactions. Part VII: synthesis and antitumor, anti-inflammatory, and antioxidant properties of 1,3,4‒thiadiazoline‒6-sulfanylthiopyran-4(1H)-one hybrids
The reaction of N′’(aryl)benzothiohydrazides with 2-chloro-6-((substituted)amino)-3-nitro-4-oxo-4H-thieno[2,3-...
Proceedings of the ICSDI 2024 Volume 1
Proceedings of the ICSDI 2024 Volume 1
This book offers a comprehensive overview of the latest research, innovations, and practical applications in the field of ...
A promising class of antiprotozoal agents, design and synthesis of novel Pyrimidine–Cinnamoyl hybrids
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Multicomponent syntheses enable the discovery of novel quisinostat-derived chemotypes as histone deacetylase inhibitors
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Design, synthesis, and X-ray structural studies of a series of highly potent, selective, and drug-like G protein-coupled receptor kinase 5 inhibitors
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Synthesis and evaluation of a novel BODIPY fluorescent probe targeting integrin αvβ3 for cancer diagnosis
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Design, synthesis, and biological evaluation of novel pleuromutilin derivatives with methicillin-resistant Staphylococcus aureus -targeting phenol linker groups
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