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CN1699 Our Business - Guide for Agents
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Global Medical University
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1466
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1273
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414
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841
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3803
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298
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78
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4672
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22198
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204
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4989
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8198
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14998
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89
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35
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49
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391
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275
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Discovery of novel 2-hydroxyl-4-benzyloxybenzyl aniline derivatives as potential multifunctional agents for the treatment of Parkinson's disease
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Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents
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Memantine derived compounds as potent in vitro inhibitors of urease: Repurposing of memantine, sonication assisted derivatization and in vitro enzyme inhibition, kinetics and molecular docking studies
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Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors
Viruses have been recognized as the etiological agents responsible for many pathological conditions ranging from asymptoma...
European Journal Of Medicinal Chemistry
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Design, synthesis and biological activity of hybrid antifungals derived from fluconazole and mebendazole
A novel series of triazole alcohol antifungals bearing a 5-benzoylbenzimidazol-2-ylthio side chain have been designed and ...
European Journal Of Medicinal Chemistry
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1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation
Among the different hallmarks of cancer, deregulation of cellular metabolism turned out to be an essential mechanism in pr...
European Journal Of Medicinal Chemistry
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Synthesis and evaluation of N-sulfonylpiperidine-3-carboxamide derivatives as capsid assembly modulators inhibiting HBV in vitro and in HBV-transgenic mice
The hepatitis B virus (HBV) capsid assembly modulators (CAMs) have been developed as effective anti-HBV agents in the trea...
European Journal Of Medicinal Chemistry
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Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance
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European Journal Of Medicinal Chemistry
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Nonsteroidal anti-inflammatory drugs (NSAIDs) and nucleotide analog GS-441524 conjugates with potent in vivo efficacy against coronaviruses
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European Journal Of Medicinal Chemistry
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Discovery of multi-target directed 3-OH pyrrolidine derivatives through a semisynthetic approach from alkaloid vasicine for the treatment of Alzheimer's disease
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European Journal Of Medicinal Chemistry
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Elevated labile iron in castration–resistant prostate cancer is targetable with ferrous iron–activatable antiandrogen therapy
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European Journal Of Medicinal Chemistry
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Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis
Acute lung injury (ALI) and sepsis, characterized by systemic inflammatory response syndrome, remain the major causes of d...
European Journal Of Medicinal Chemistry
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Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors
The alkylindole (AI), WIN55212-2, modulates the activity of several proteins, including cannabinoid receptors 1 and 2 (CB1...
European Journal Of Medicinal Chemistry
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Design and evaluation of dibenzoazepine-tetrahydroisoquinoline hybrids as potential P-glycoprotein inhibitors against multidrug resistant K562/A02 cells
Multidrug resistance (MDR) caused by P-glycoprotein (P-gp) is a main barrier to the success of cancer chemotherapies. In t...
European Journal Of Medicinal Chemistry
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Development and Evaluation of Self-Emulsifying Drug-Delivery System–Based Tablets for Simvastatin, a BCS Class II Drug
This study aimed at formulating and characterization of SEDDS-based tablets for simvastatin using castor and olive oils as...
Drug Design Development And Therapy
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Synthesis, cytotoxicity, Pan-HDAC inhibitory activity and docking study of new N-(2-aminophenyl)-2-methylquinoline-4-carboxamide and (E)-N-(2-aminophenyl)-2-styrylquinoline-4-carboxamide derivatives as anticancer agents
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Medicinal Chemistry Research
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Medicinal uses, phytochemistry, pharmacology, and taxonomy of Poygonum aviculare L.: a comprehensive review
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Effect of fluoride ions on coordination structure of titanium in molten NaCl-KCl
The effects of fluoride ions (F−) on the electrochemical behavior and coordination properties of titanium ions (Tin+...
Journal Of Structural Chemistry
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Combined “Gateway” and “Spillover” effects originated from a CeNi5 alloy catalyst for hydrogen storage of MgH2
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Journal Of Structural Chemistry
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Solvent extraction and separation of cobalt from leachate of spent lithium-ion battery cathodes with N263 in nitrite media
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Journal Of Structural Chemistry
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Reaction behavior and non-isothermal kinetics of suspension magnetization roasting of limonite and siderite
In order to develop limonite and decrease CO2 emissions, siderite is proposed as a clean reductant for suspension magnetiz...
Journal Of Structural Chemistry
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First-principles calculations of Ni-(Co)-Mn-Cu-Ti all-d-metal Heusler alloy on martensitic transformation, mechanical and magnetic properties
The martensitic transformation, mechanical, and magnetic properties of the Ni2Mn1.5−xCuxTi0.5 (x = 0.125, 0.25, 0.37...
Journal Of Structural Chemistry
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Metallurgical properties of CaO-SiO2-Al2O3-4.6wt%MgO-Fe2O3 slag system pertaining to spent automotive catalyst smelting
The metallurgical properties of the CaO-SiO2-Al2O3-4.6wt%MgO-Fe2O3 slag system, formed by the co-treatment process of spen...
Journal Of Structural Chemistry
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Optimization on microstructure, mechanical properties and damping capacities of duplex structured Mg-8Li-4Zn-1Mn alloys
Optimizing the mechanical properties and damping capacity of the duplex-structured Mg-Li-Zn-Mn alloy by tailoring the micr...
Journal Of Structural Chemistry
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Effect of ball milling time on the microstructure and compressive properties of the Fe-Mn-Al porous steel
In the present work, Fe-Mn-Al-C powder mixtures were manufactured by elemental powders with different ball milling time, a...
Journal Of Structural Chemistry
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Microstructure, segregation and precipitate evolution in directionally solidified GH4742 superalloy
The evolution of microstructure, elemental segregation, and precipitation in GH4742 superalloy under a wide range of cooli...
Journal Of Structural Chemistry
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Influence of complicated faults on the differentiation and accumulation of in-situ stress in deep rock mass
High geostress will become a normality in the deep because in-situ stress rises linearly with depth. The geological struct...
Journal Of Structural Chemistry
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Preparation and property of self-sealed plasma electrolytic oxide coating on magnesium alloy
Plasma electrochemical oxidation (PEO) is a surface modification technology to form ceramic coatings on magnesium alloys. ...
Journal Of Structural Chemistry
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Numerical investigation of the mechanical behavior of the backfill—rock composite structure under triaxial compression
To ensure safe and economical backfill mining, the mechanical response of the backfill—rock interaction system needs...
Journal Of Structural Chemistry
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