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Medicina, Vol. 58, Pages 1350: Secondary Hemophagocytic Syndrome in a Patient with Plasma Cell Myeloma and CNS Involvement Treated with Lenalidomide
Medicina, Vol. 58, Pages 1350: Secondary Hemophagocytic Syndrome in a Patient with Plasma Cell Myeloma and CNS Involvement Treated with Lenalidomide
We present an extremely rare case report of a 29-year-old multiple myeloma patient with central nervous system involvement...
Medicina, Vol. 58, Pages 1348: Identifying Factors Predicting Kidney Graft Survival in Chile Using Elastic-Net-Regularized Cox’s Regression
Medicina, Vol. 58, Pages 1348: Identifying Factors Predicting Kidney Graft Survival in Chile Using Elastic-Net-Regularized Cox’s Regression
Background and Objectives: We developed a predictive statistical model to identify donor–recipient characteristi...
Ad-hoc modifications of cyclic mimetics of SOCS1 protein: Structural and functional insights
Suppressors of cytokine signaling 1 (SOCS1) protein, a negative regulator of the Janus kinase (JAK)-signal transducer and ...
Review of bioactivity and structure-activity relationship on baicalein (5,6,7-trihydroxyflavone) and wogonin (5,7-dihydroxy-8-methoxyflavone) derivatives: Structural modifications inspired from flavonoids in Scutellaria baicalensis
Baicalein (5,6,7-trihydroxyflavone) and wogonin (5,7-dihydroxy-8-methoxyflavone), as typical flavonoids isolated from Scut...
Design, synthesis, and biological evaluation of low-toxic lappaconitine derivatives as potential analgesics
The C18-diterpenoid alkaloid lappaconitine (LA) is a non-addictive analgesic used in China. The toxicity (LD50 = 11.7 mg/k...
Design, synthesis, and biological evaluation of ocotillol derivatives fused with 2-aminothiazole via A-ring as modulators of P-glycoprotein-mediated multidrug resistance
Overexpression of P-glycoprotein (P-gp) plays a key role in the development of multidrug resistance (MDR), the major reaso...
Design, synthesis, and biological evaluation of Wee1 kinase degraders
Proteolysis targeting chimera (PROTAC) technology has received widespread attention in recent years as a promising strateg...
The Temporal Topography of Central Serous Chorioretinopathy in the Chinchilla Rabbits Induced by Intravenous Injection of Adrenaline: An in vivo Study
The Temporal Topography of Central Serous Chorioretinopathy in the Chinchilla Rabbits Induced by Intravenous Injection of Adrenaline: An in vivo Study
The Temporal Topography of Central Serous Chorioretinopathy in the Chinchilla Rabbits Induced by Intravenous Injection of ...
Synthesis and Bioactivity Evaluation of a Novel 1,2,4-Oxadiazole Derivative in vitro and in 3×Tg Mice
Synthesis and Bioactivity Evaluation of a Novel 1,2,4-Oxadiazole Derivative in vitro and in 3×Tg Mice
We found a novel 1,2,4-oxadiazole derivative (wyc-7-20) with low toxicity on SH-SY5Y and HepG2 cells and improvement of th...
Endocannabinoid Signaling
Endocannabinoid Signaling
​This second edition provides new and updated chapters detailing all major elements of the eCB system and identification o...
Advances on Mechanics, Design Engineering and Manufacturing IV
Advances on Mechanics, Design Engineering and Manufacturing IV
The proceedings of JCM 2022 discusses methods, technologies and applications of engineering design in additive manufacturi...
Medicina, Vol. 58, Pages 1345: Thyroid-Bed Schwannoma Mimicking a Thyroid Neoplasm: A Challenging Diagnosis: Report of a Case and Literature Review
Medicina, Vol. 58, Pages 1345: Thyroid-Bed Schwannoma Mimicking a Thyroid Neoplasm: A Challenging Diagnosis: Report of a Case and Literature Review
Background: Schwannomas, also called neurinomas, are rare benign tumors of the neural cells that can develop from the shea...
Medicina, Vol. 58, Pages 1344: Crohn’s Disease and Jejunal Artery Aneurysms: A Report of the First Case and a Review of the Literature
Medicina, Vol. 58, Pages 1344: Crohn’s Disease and Jejunal Artery Aneurysms: A Report of the First Case and a Review of the Literature
Background and Objectives: Jejunal artery (JA) and ileal artery (IA) aneurysms constitute less than 3% of all visceral art...
Medicina, Vol. 58, Pages 1342: External Apical Root Resorption in Orthodontic Patients Who Practice Combat Sports: A Case-Control Observational Pilot Study
Medicina, Vol. 58, Pages 1342: External Apical Root Resorption in Orthodontic Patients Who Practice Combat Sports: A Case-Control Observational Pilot Study
Orthodontic treatment could lead to undesirable effects such as external apical root resorption (EARR). Moreover, trauma t...
Medicina, Vol. 58, Pages 1346: Potential Association between Subclinical Hypothyroidism and Childhood Migraine
Medicina, Vol. 58, Pages 1346: Potential Association between Subclinical Hypothyroidism and Childhood Migraine
Background and Objectives: Migraine is caused by genetic susceptibility that is triggered by environmental as well as biol...
Medicina, Vol. 58, Pages 1347: Misfit of Implant-Supported Zirconia (Y-TZP) CAD-CAM Framework Compared to Non-Zirconia Frameworks: A Systematic Review
Medicina, Vol. 58, Pages 1347: Misfit of Implant-Supported Zirconia (Y-TZP) CAD-CAM Framework Compared to Non-Zirconia Frameworks: A Systematic Review
Objective: The aim of the study was to systematically review the overall outcomes of studies comparing the misfit of yttri...
JPM, Vol. 12, Pages 1576: Predictors and Prognostic Impact of Left Ventricular Ejection Fraction Recovery after Impella-Supported Percutaneous Coronary Interventions in Acute Myocardial Infarction
JPM, Vol. 12, Pages 1576: Predictors and Prognostic Impact of Left Ventricular Ejection Fraction Recovery after Impella-Supported Percutaneous Coronary Interventions in Acute Myocardial Infarction
Aim: The aim of our study is to assess the predictors and the prognostic role of left ventricle ejection fraction (LVEF) r...
JPM, Vol. 12, Pages 1574: Bibliometric Analysis of the Scientific Production on Compassion Fatigue
JPM, Vol. 12, Pages 1574: Bibliometric Analysis of the Scientific Production on Compassion Fatigue
Background: Compassion fatigue is a common phenomenon among healthcare professionals and includes several concepts that sh...
An in vitro and in silico α-amylase/α-glucosidase/protein tyrosine phosphatase 1 beta & radical scavenging profiling of the 3,5,7-tricarbo substituted 1H-indazoles
An in vitro and in silico α-amylase/α-glucosidase/protein tyrosine phosphatase 1 beta & radical scavenging profiling of the 3,5,7-tricarbo substituted 1H-indazoles
A series of 3,5,7-tricarbo substituted indazoles was synthesized and evaluated for inhibitory effect in vitro against ^...
Structure–activity relationship of a housefly neuroprotective dodecapeptide that activates the nuclear factor erythroid 2-related factor 2 pathway
Structure–activity relationship of a housefly neuroprotective dodecapeptide that activates the nuclear factor erythroid 2-related factor 2 pathway
Neuroprotective antioxidants, especially peptide-based antioxidants, are effective against oxidative stress in neurodegene...
Medicina, Vol. 58, Pages 1323: Impact of Anticoagulants in Reducing Mortality and Disability in Cardioembolic Stroke Patients
Medicina, Vol. 58, Pages 1323: Impact of Anticoagulants in Reducing Mortality and Disability in Cardioembolic Stroke Patients
Background and Objectives: Stroke is currently the second most common cause of death and disability-adjusted life years wo...
Medicina, Vol. 58, Pages 1326: Interdental Papillary Reconstruction by Microtunnelling Technique Using Autologous Biomatrices—A Randomised Controlled Clinical Trial
Medicina, Vol. 58, Pages 1326: Interdental Papillary Reconstruction by Microtunnelling Technique Using Autologous Biomatrices—A Randomised Controlled Clinical Trial
Background and objectives: The study aimed to evaluate and compare the amount of papillary gain and black triangle height ...
Medicina, Vol. 58, Pages 1325: Sleep Disorders and Their Associated Factors during the COVID-19 Pandemic: Data from Peruvian Medical Students
Medicina, Vol. 58, Pages 1325: Sleep Disorders and Their Associated Factors during the COVID-19 Pandemic: Data from Peruvian Medical Students
Background and objectives: Sleep disorders are a common public health problem among college students. The objective of thi...
Medicina, Vol. 58, Pages 1328: The Impact of Revascularization in a Patient with Atypical Manifestations of Hypoperfusion
Medicina, Vol. 58, Pages 1328: The Impact of Revascularization in a Patient with Atypical Manifestations of Hypoperfusion
Background and Objectives: Carotid revascularization is one of the most effective treatment options in patients with sever...
Medicina, Vol. 58, Pages 1330: Loss of Expression of Antiangiogenic Protein FKBPL in Endometrioid Endometrial Carcinoma: Implications for Clinical Practice
Medicina, Vol. 58, Pages 1330: Loss of Expression of Antiangiogenic Protein FKBPL in Endometrioid Endometrial Carcinoma: Implications for Clinical Practice
Background and Objectives: FK506 binding protein like (FKBPL) is a member of the immunophilin family, with anti-angiogenic...
Medicina, Vol. 58, Pages 1327: Integrating Radiosensitivity Gene Signature Improves Glioma Outcome and Radiotherapy Response Prediction
Medicina, Vol. 58, Pages 1327: Integrating Radiosensitivity Gene Signature Improves Glioma Outcome and Radiotherapy Response Prediction
Response to radiotherapy (RT) in gliomas varies widely between patients. It is necessary to identify glioma-associated rad...
Medicina, Vol. 58, Pages 1329: Clear Cell Renal Cell Carcinoma, Diagnostic and Therapeutic Difficulties, Case Report and Literature Review
Medicina, Vol. 58, Pages 1329: Clear Cell Renal Cell Carcinoma, Diagnostic and Therapeutic Difficulties, Case Report and Literature Review
Nephroblastoma is the most common kidney tumour in children, constitutes about 85% of cases. Although renal cell carcinoma...
Medicina, Vol. 58, Pages 1333: Quantitative Assessment of Liver Impairment in Chronic Viral Hepatitis with [99mTc]Tc-Mebrofenin: A Noninvasive Attempt to Stage Viral Hepatitis-Associated Liver Fibrosis
Medicina, Vol. 58, Pages 1333: Quantitative Assessment of Liver Impairment in Chronic Viral Hepatitis with [99mTc]Tc-Mebrofenin: A Noninvasive Attempt to Stage Viral Hepatitis-Associated Liver Fibrosis
Background and objectives—Chronic viral hepatitis B and C infections are one of the leading causes of chronic li...
Medicina, Vol. 58, Pages 1339: Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy
Medicina, Vol. 58, Pages 1339: Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy
Background and Objectives: A prognosis for kids with pediatric dilated cardiomyopathy (PDCM) is urgently needed to identif...
Medicina, Vol. 58, Pages 1335: A Psychoanalytic-Derived Brief Psychotherapeutic Approach in the Treatment of Major Depression: Monotherapy Studies
Medicina, Vol. 58, Pages 1335: A Psychoanalytic-Derived Brief Psychotherapeutic Approach in the Treatment of Major Depression: Monotherapy Studies
Over the years, short term psychodynamic therapy (STPP) has been broadly researched in order to evaluate its efficacy in t...
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