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Association of four types of vascular access including arterial superficialization with mortality in maintenance hemodialysis patients: a nationwide cohort study in Japan
Association of four types of vascular access including arterial superficialization with mortality in maintenance hemodialysis patients: a nationwide cohort study in Japan
Introduction: Vascular access usage varies widely across countries. Previous studies have evaluated the association of cli...
Contents Vol. 53, 2022
Contents Vol. 53, 2022
American Jour...
Triglycerides and Renal Outcomes according to Albuminuria and in Consideration of other Metabolic Syndrome Components in Diabetic US Veterans
Triglycerides and Renal Outcomes according to Albuminuria and in Consideration of other Metabolic Syndrome Components in Diabetic US Veterans
Objective: Hypertriglyceridemia, a component of the metabolic syndrome, is a known independent predictor of albuminuria an...
Extremely Low Dose of Erythropoiesis-Stimulating Agent May be Associated with Increased Mortality in Hemodialysis Patients
Extremely Low Dose of Erythropoiesis-Stimulating Agent May be Associated with Increased Mortality in Hemodialysis Patients
Introduction: Although high dose erythropoiesis-stimulating agent (ESA) has been shown to increase mortality risk and adve...
Biomarkers of Covert Acid Stress in Patients with Chronic Kidney Disease: A Cross-Sectional Study
Biomarkers of Covert Acid Stress in Patients with Chronic Kidney Disease: A Cross-Sectional Study
<b><i>Introduction:</i></b> Like metabolic acidosis, earlier stages of acid (H+) stress, including...
Clinical Significance of Persistent Hematuria Degrees in Primary IgA Nephropathy: A Propensity Score-Matched Analysis of A 10-year Follow-up Cohort
Clinical Significance of Persistent Hematuria Degrees in Primary IgA Nephropathy: A Propensity Score-Matched Analysis of A 10-year Follow-up Cohort
Abstract Introduction: The clinical significance of persistent hematuria degrees hasn't been expounded in primary IgA ...
IgA Nephropathy with Crescents: A Single-Center Experience
IgA Nephropathy with Crescents: A Single-Center Experience
<b><i>Introduction:</i></b> The presence of crescents in IgA nephropathy (IgAN) has been associate...
Indicators of Kidney Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease Treated With Dulaglutide
Indicators of Kidney Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease Treated With Dulaglutide
Introduction: In the AWARD-7 study in patients with type 2 diabetes and moderate-to-severe chronic kidney disease, once-we...
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D)
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D)
Introduction: Hyporesponsiveness to erythropoiesis-stimulating agents (ESAs) affects 10–15% of the chronic dialysis popul...
Mineralocorticoid receptor (MR)-associated mechanisms in diabetic kidney disease and clinical significance of MR antagonists
Mineralocorticoid receptor (MR)-associated mechanisms in diabetic kidney disease and clinical significance of MR antagonists
Background: Diabetic kidney disease (DKD) is a common disorder with multiple serious clinical implications, including an i...
Biomarkers of covert acid stress in patients with CKD: A cross-sectional study
Biomarkers of covert acid stress in patients with CKD: A cross-sectional study
Introduction: Like metabolic acidosis, earlier stages of acid (H+) stress, including an ongoing H+ challenge in the form ...
IgA Nephropathy (IgAN) with Crescents: A single center experience
IgA Nephropathy (IgAN) with Crescents: A single center experience
Introduction: The presence of crescents in IgA nephropathy (IgAN) has been associated with a poor prognosis. We assess th...
Challenges and Approach to Identifying Individuals with Salt Sensitivity of Blood Pressure
Challenges and Approach to Identifying Individuals with Salt Sensitivity of Blood Pressure
Background: Salt sensitivity of blood pressure (SSBP) is a trait observed in both humans and animals, characterized by an ...
Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes
Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes
Introduction: Diabetes is a leading cause of end-stage kidney disease (ESKD). Biomarkers of tubular health may prognostica...
Hemodialysis Effects on Autonomic Function: Results of Linear and Nonlinear Analysis of Heart Rate Variability at Rest and in Response to Physical and Mental Stress Tests
Hemodialysis Effects on Autonomic Function: Results of Linear and Nonlinear Analysis of Heart Rate Variability at Rest and in Response to Physical and Mental Stress Tests
<b><i>Introduction:</i></b> Cardiac arrhythmias are the most common cause of death in hemodialysis...
Serum sclerostin levels and mortality in hemodialysis patients: An 8-year prospective study
Serum sclerostin levels and mortality in hemodialysis patients: An 8-year prospective study
Introduction: Sclerostin is an osteocyte-derived inhibitor of bone formation and is increased in kidney failure. Sclerosti...
Clinical Outcomes of Persistent Severe Acute Kidney Injury among Patients with Kidney Disease Improving Global Outcomes Stage 2 or 3 Acute Kidney Injury
Clinical Outcomes of Persistent Severe Acute Kidney Injury among Patients with Kidney Disease Improving Global Outcomes Stage 2 or 3 Acute Kidney Injury
<b><i>Introduction:</i></b> The burden of persistent (≥3 days) severe AKI (PS-AKI) is poorly descr...
Proteinuria and Risk for Heart Failure in 55,191 Patients Having History of Cancer
Proteinuria and Risk for Heart Failure in 55,191 Patients Having History of Cancer
<b><i>Introduction:</i></b> We examined the association of proteinuria with the risk for heart fai...
Domains for a Comprehensive Geriatric Assessment of Older Adults with Chronic Kidney Disease: Results from the CRIC Study
Domains for a Comprehensive Geriatric Assessment of Older Adults with Chronic Kidney Disease: Results from the CRIC Study
Introduction: A comprehensive geriatric assessment (CGA) tailored to the chronic kidney disease (CKD) population would yie...
Hemodialysis effects on autonomic function: results of linear and non-linear analysis of heart-rate-variability at rest and in response to physical and mental stress tests
Hemodialysis effects on autonomic function: results of linear and non-linear analysis of heart-rate-variability at rest and in response to physical and mental stress tests
Introduction: Cardiac arrhythmias are the most common cause of death in hemodialysis. Autonomic dysfunction plays a centra...
Cardiovascular Risk Prediction in Chronic Kidney Disease
Cardiovascular Risk Prediction in Chronic Kidney Disease
As one of the main complications of chronic kidney disease (CKD), the incidence of cardiovascular disease (CVD) in CKD pat...
Metabolic Basis and Pathogenesis of Skeletal Muscle Dysfunction as Cause of Frailty in Chronic Kidney Disease
Metabolic Basis and Pathogenesis of Skeletal Muscle Dysfunction as Cause of Frailty in Chronic Kidney Disease
<b><i>Background:</i></b> Frailty is common in patients with chronic kidney disease (CKD), as is i...
Serum Calciprotein Monomers and Chronic Kidney Disease Progression
Serum Calciprotein Monomers and Chronic Kidney Disease Progression
<b><i>Introduction:</i></b> Elevated levels of fibroblast growth factor-23 (FGF23) in chronic kidn...
Clinical outcomes of persistent severe acute kidney injury among patients with KDIGO stage 2 or 3 AKI
Clinical outcomes of persistent severe acute kidney injury among patients with KDIGO stage 2 or 3 AKI
Introduction: The burden of persistent (≥ 3 days) severe AKI (PS-AKI) is poorly described among inpatients with stage 2-3 ...
Renal mechanisms for hypercalciuria induced by metabolic acidosis
Renal mechanisms for hypercalciuria induced by metabolic acidosis
Background: In metabolic acidosis, a negative calcium balance is induced by decreased renal tubular calcium reabsorption. ...
Overall Adverse Event Profile of Vadadustat for the Treatment of Anemia Associated With Chronic Kidney Disease in Phase 3 Trials
Overall Adverse Event Profile of Vadadustat for the Treatment of Anemia Associated With Chronic Kidney Disease in Phase 3 Trials
Introduction: Anemia frequently occurs in chronic kidney disease (CKD), is associated with poor quality of life and cardio...
Cystatin C and estimation of GFR in the emergency department
Cystatin C and estimation of GFR in the emergency department
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Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies
Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies
<b><i>Introduction:</i></b> C3 glomerulopathy (C3G) is an ultrarare, chronic and progressive nephr...
Clinical Effectiveness of Calcium Oxalate Stone Treatments
Clinical Effectiveness of Calcium Oxalate Stone Treatments
Introduction: Lowering kidney stone risk and urine calcium oxalate supersaturation is a primary clinical focus for kidney ...
Baseline Clinical Characteristics and Complement Biomarkers of Patients with C3 Glomerulopathy Enrolled in Two Phase 2 Studies Investigating the Factor D Inhibitor Danicopan
Baseline Clinical Characteristics and Complement Biomarkers of Patients with C3 Glomerulopathy Enrolled in Two Phase 2 Studies Investigating the Factor D Inhibitor Danicopan
<b><i>Introduction:</i></b> C3 glomerulopathy (C3G) is a rare, progressive kidney disease resultin...
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