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Extremely Low Dose of Erythropoiesis-Stimulating Agent May be Associated with Increased Mortality in Hemodialysis Patients
Extremely Low Dose of Erythropoiesis-Stimulating Agent May be Associated with Increased Mortality in Hemodialysis Patients
Introduction: Although high dose erythropoiesis-stimulating agent (ESA) has been shown to increase mortality risk and adve...
IgA Nephropathy with Crescents: A Single-Center Experience
IgA Nephropathy with Crescents: A Single-Center Experience
<b><i>Introduction:</i></b> The presence of crescents in IgA nephropathy (IgAN) has been associate...
Indicators of Kidney Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease Treated With Dulaglutide
Indicators of Kidney Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease Treated With Dulaglutide
Introduction: In the AWARD-7 study in patients with type 2 diabetes and moderate-to-severe chronic kidney disease, once-we...
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D)
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D)
Introduction: Hyporesponsiveness to erythropoiesis-stimulating agents (ESAs) affects 10–15% of the chronic dialysis popul...
Mineralocorticoid receptor (MR)-associated mechanisms in diabetic kidney disease and clinical significance of MR antagonists
Mineralocorticoid receptor (MR)-associated mechanisms in diabetic kidney disease and clinical significance of MR antagonists
Background: Diabetic kidney disease (DKD) is a common disorder with multiple serious clinical implications, including an i...
Biomarkers of covert acid stress in patients with CKD: A cross-sectional study
Biomarkers of covert acid stress in patients with CKD: A cross-sectional study
Introduction: Like metabolic acidosis, earlier stages of acid (H+) stress, including an ongoing H+ challenge in the form ...
IgA Nephropathy (IgAN) with Crescents: A single center experience
IgA Nephropathy (IgAN) with Crescents: A single center experience
Introduction: The presence of crescents in IgA nephropathy (IgAN) has been associated with a poor prognosis. We assess th...
Challenges and Approach to Identifying Individuals with Salt Sensitivity of Blood Pressure
Challenges and Approach to Identifying Individuals with Salt Sensitivity of Blood Pressure
Background: Salt sensitivity of blood pressure (SSBP) is a trait observed in both humans and animals, characterized by an ...
Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes
Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes
Introduction: Diabetes is a leading cause of end-stage kidney disease (ESKD). Biomarkers of tubular health may prognostica...
Serum sclerostin levels and mortality in hemodialysis patients: An 8-year prospective study
Serum sclerostin levels and mortality in hemodialysis patients: An 8-year prospective study
Introduction: Sclerostin is an osteocyte-derived inhibitor of bone formation and is increased in kidney failure. Sclerosti...
Proteinuria and Risk for Heart Failure in 55,191 Patients Having History of Cancer
Proteinuria and Risk for Heart Failure in 55,191 Patients Having History of Cancer
<b><i>Introduction:</i></b> We examined the association of proteinuria with the risk for heart fai...
Domains for a Comprehensive Geriatric Assessment of Older Adults with Chronic Kidney Disease: Results from the CRIC Study
Domains for a Comprehensive Geriatric Assessment of Older Adults with Chronic Kidney Disease: Results from the CRIC Study
Introduction: A comprehensive geriatric assessment (CGA) tailored to the chronic kidney disease (CKD) population would yie...
Cardiovascular Risk Prediction in Chronic Kidney Disease
Cardiovascular Risk Prediction in Chronic Kidney Disease
As one of the main complications of chronic kidney disease (CKD), the incidence of cardiovascular disease (CVD) in CKD pat...
Serum Calciprotein Monomers and Chronic Kidney Disease Progression
Serum Calciprotein Monomers and Chronic Kidney Disease Progression
<b><i>Introduction:</i></b> Elevated levels of fibroblast growth factor-23 (FGF23) in chronic kidn...
Clinical outcomes of persistent severe acute kidney injury among patients with KDIGO stage 2 or 3 AKI
Clinical outcomes of persistent severe acute kidney injury among patients with KDIGO stage 2 or 3 AKI
Introduction: The burden of persistent (≥ 3 days) severe AKI (PS-AKI) is poorly described among inpatients with stage 2-3 ...
Renal mechanisms for hypercalciuria induced by metabolic acidosis
Renal mechanisms for hypercalciuria induced by metabolic acidosis
Background: In metabolic acidosis, a negative calcium balance is induced by decreased renal tubular calcium reabsorption. ...
Overall Adverse Event Profile of Vadadustat for the Treatment of Anemia Associated With Chronic Kidney Disease in Phase 3 Trials
Overall Adverse Event Profile of Vadadustat for the Treatment of Anemia Associated With Chronic Kidney Disease in Phase 3 Trials
Introduction: Anemia frequently occurs in chronic kidney disease (CKD), is associated with poor quality of life and cardio...
Clinical Effectiveness of Calcium Oxalate Stone Treatments
Clinical Effectiveness of Calcium Oxalate Stone Treatments
Introduction: Lowering kidney stone risk and urine calcium oxalate supersaturation is a primary clinical focus for kidney ...