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Enduring effects of acute prenatal ischemia in rat soleus muscle, and protective role of erythropoietin
Enduring effects of acute prenatal ischemia in rat soleus muscle, and protective role of erythropoietin
Motor disorders are considered to originate mainly from brain lesions. Placental dysfunction or maternal exposure to a per...
Muscle spindle receptors and their impact on Parkinson´s disease and Cerebral Palsy subjects
Muscle spindle receptors and their impact on Parkinson´s disease and Cerebral Palsy subjects
In some neurological conditions, like Parkinson’s disease (PD) and Cerebral Palsy (CP), as well as with ageing, musc...
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
Tubular aggregate myopathy (TAM) is a rare myopathy characterized by muscle weakness and myalgia. Muscle fibers from TAM p...
Four phases of a force transient emerge from a binary mechanical system
Four phases of a force transient emerge from a binary mechanical system
Accurate models of muscle contraction are important for understanding both muscle performance and the therapeutics that en...
Arginine ingestion inhibits phagocyte invasion in eccentrically contracted rat fast-twitch muscle
Arginine ingestion inhibits phagocyte invasion in eccentrically contracted rat fast-twitch muscle
Eccentric contraction (ECC) has been shown to induce leukocyte invasion into skeletal muscle, resulting in muscle inflamma...
Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction
Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction
Neuromuscular junctions are the synapses between motor neurons and skeletal muscle fibers, which mediate voluntary muscle ...
Post-transcriptional regulation of myogenic transcription factors during muscle development and pathogenesis
Post-transcriptional regulation of myogenic transcription factors during muscle development and pathogenesis
The transcriptional regulation of skeletal muscle (SKM) development (myogenesis) has been documented for over 3 decades an...
Nitric oxide and ion channels mediate l-cysteine-induced inhibition of colonic smooth muscle contraction
Nitric oxide and ion channels mediate l-cysteine-induced inhibition of colonic smooth muscle contraction
Previous studies have suggested that l-cysteine regulates gut motility through hydrogen sulfide. However, the mechanisms i...
The role of ZBP1 in eccentric exercise-induced skeletal muscle necroptosis
The role of ZBP1 in eccentric exercise-induced skeletal muscle necroptosis
This study aimed to explore the occurrence of necroptosis in skeletal muscle after eccentric exercise and investigate the ...
From amino-acid to disease: the effects of oxidation on actin-myosin interactions in muscle
From amino-acid to disease: the effects of oxidation on actin-myosin interactions in muscle
Actin-myosin interactions form the basis of the force-producing contraction cycle within the sarcomere, serving as the pri...
The cryo-EM 3D image reconstruction of isolated Lethocerus indicus Z-discs
The cryo-EM 3D image reconstruction of isolated Lethocerus indicus Z-discs
The Z-disk of striated muscle defines the ends of the sarcomere, which repeats many times within the muscle fiber. Here we...
Obituary: Professor John Michael Squire
Obituary: Professor John Michael Squire
In 1973 John joined Imperial College as lecturer in the Department of Metallurgy and Materials Science. This transition fr...
Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio
Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio
Actin, tropomyosin and troponin, the proteins that comprise the contractile apparatus of the cardiac thin filament, are hi...