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Construction and evaluation of glycoprotein-based nucleic acid vaccines for Marburg virus
Construction and evaluation of glycoprotein-based nucleic acid vaccines for Marburg virus
Marburg virus (MARV) is a zoonotic virus that can infect humans and non-human primates (NHPs) and lead to a fatal Marburg ...
Inhibiting lipid droplet biogenesis enhances host protection against hypervirulent Klebsiella pneumoniae infections
Inhibiting lipid droplet biogenesis enhances host protection against hypervirulent Klebsiella pneumoniae infections
Hypervirulent Klebsiella pneumoniae (hvKp), an emerging Kp subtype, has become a serious global pathogen. However, the inf...
MPXV infection impairs IFN response but is partially sensitive to IFN-γ antiviral effect
MPXV infection impairs IFN response but is partially sensitive to IFN-γ antiviral effect
The recent outbreak of monkeypox virus (MPXV) has caused global concern. How the virus evades the interferon (IFN) respons...
Engineered bispecific antibodies with enhanced breadth and potency against SARS-CoV-2 variants and SARS-related coronaviruses
Engineered bispecific antibodies with enhanced breadth and potency against SARS-CoV-2 variants and SARS-related coronaviruses
The concern of COVID-19 persists due to the continuous emergence of variants and the potential spillover of animal coronav...
Cellular immunity to nucleoproteins (NP) of Crimean-Congo hemorrhagic fever virus (CCHFV) and Hazara Virus (HAZV)
Cellular immunity to nucleoproteins (NP) of Crimean-Congo hemorrhagic fever virus (CCHFV) and Hazara Virus (HAZV)
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a globally significant vector-borne pathogen with no internationally-lice...
Exploration of compounds to inhibit the Panton-Valentine leukocidin of Staphylococcus aureus
Exploration of compounds to inhibit the Panton-Valentine leukocidin of Staphylococcus aureus
The Panton-Valentine leukocidin (PVL) of Staphylococcus aureus is associated with necrotizing infections. After binding to...
Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases
Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases
Carl Flügge is best known for the promotion of studies demonstrating the transmission of all manner of infections, bu...
Analytical and clinical evaluation of a novel real-time PCR-based detection kit for Mpox virus
Analytical and clinical evaluation of a novel real-time PCR-based detection kit for Mpox virus
Outbreaks of emerging diseases, like Mpox in 2022, pose unprecedented challenges to global healthcare systems. Although Mp...
Repurposing promethazine hydrochloride to inhibit biofilm formation against Burkholderia thailandensis
Repurposing promethazine hydrochloride to inhibit biofilm formation against Burkholderia thailandensis
Melioidosis is a severe infectious disease caused by Burkholderia pseudomallei, an intracellular pathogen with a high mort...
Alteration of β-glucan in the emerging fungal pathogen Candida auris leads to immune evasion and increased virulence
Alteration of β-glucan in the emerging fungal pathogen Candida auris leads to immune evasion and increased virulence
Candida auris is an emerging pathogenic yeast that has been categorized as a global public health threat and a critical pr...
One-dose intradermal rabies booster enhances rabies antibody production and avidity maturation
One-dose intradermal rabies booster enhances rabies antibody production and avidity maturation
The incidence of rabies in Thailand reached its peak in 2018 with 18 human deaths. Preexposure prophylaxis (PrEP) vaccinat...
Quantitative assay to analyze neutralization and inhibition of authentic Middle East respiratory syndrome coronavirus
Quantitative assay to analyze neutralization and inhibition of authentic Middle East respiratory syndrome coronavirus
To date, there is no licensed vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV). Therefore, MERS-CoV is ...
Inflammation, the kynurenines, and mucosal injury during human experimental enterotoxigenic Escherichia coli infection
Inflammation, the kynurenines, and mucosal injury during human experimental enterotoxigenic Escherichia coli infection
Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea in children and travelers, especially in low- an...
Advances in the understanding of circRNAs that influence viral replication in host cells
Advances in the understanding of circRNAs that influence viral replication in host cells
Circular RNAs (circRNAs) are non-coding RNAs discovered in recent years, which are produced by back-splicing involving the...
Echinacoside, a promising sortase A inhibitor, combined with vancomycin against murine models of MRSA-induced pneumonia
Echinacoside, a promising sortase A inhibitor, combined with vancomycin against murine models of MRSA-induced pneumonia
Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogenic bacterium responsible for a range of severe infections,...