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In Memoriam Tribute to Michael R. Rosen: A Life Well Lived
In Memoriam Tribute to Michael R. Rosen: A Life Well Lived
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The Significance of Statin-Associated Muscle Symptoms and Its Impact on Patient Adherence and Outcomes
The Significance of Statin-Associated Muscle Symptoms and Its Impact on Patient Adherence and Outcomes
Statin-associated muscle symptoms (SAMS) are defined as a wide spectrum of muscle symptoms, including muscle aches, weakne...
Significance of Statin-Associated Muscle Symptoms and Its Impact on Patients Adherence and Outcomes
Significance of Statin-Associated Muscle Symptoms and Its Impact on Patients Adherence and Outcomes
Abstract: Statin-associated muscle symptoms (SAMS) are one of the most common side effects of sta
LncRNA TUG1 Exacerbates Myocardial Fibrosis in Diabetic Cardiomyopathy by Modulating the microRNA-145a-5p/Cfl2 Axis
LncRNA TUG1 Exacerbates Myocardial Fibrosis in Diabetic Cardiomyopathy by Modulating the microRNA-145a-5p/Cfl2 Axis
Abstract: Nowadays, there is limited prevention and treatment for myocardial fibrosis in diabetic
Prescription Rates and Prognostic Implications of Optimally Targeted Guideline-Directed Medical Treatment in Heart Failure and Atrial Fibrillation: Insights From The MISOAC-AF Trial
Prescription Rates and Prognostic Implications of Optimally Targeted Guideline-Directed Medical Treatment in Heart Failure and Atrial Fibrillation: Insights From The MISOAC-AF Trial
Abstract: Heart failure (HF) and atrial fibrillation (AF) commonly coexist in real-life clinical
Protocatechuic Aldehyde Alleviates d-Galactose–Induced Cardiomyocyte Senescence by Regulating the TCF3/ATG5 Axis
Protocatechuic Aldehyde Alleviates d-Galactose–Induced Cardiomyocyte Senescence by Regulating the TCF3/ATG5 Axis
Abstract: Cardiomyocyte senescence is an independent risk factor for cardiovascular diseases. Pro
Renal Safety of Sacubitril/Valsartan: A Meta-Analysis of Randomized Controlled Trials
Renal Safety of Sacubitril/Valsartan: A Meta-Analysis of Randomized Controlled Trials
Abstract: As a first-line therapy, sacubitril/valsartan (S/V) plays a significant role in the tre
Effect of Dexmedetomidine on Cardiac Surgery Patients
Effect of Dexmedetomidine on Cardiac Surgery Patients
Abstract: Dexmedetomidine, an alpha-2 adrenoreceptor agonist that is widely used as a sedative me
Step-wise Lipid-Lowering Therapy: Thinking Beyond the Guidelines
Step-wise Lipid-Lowering Therapy: Thinking Beyond the Guidelines
Once we accept our limits, we go beyond them –Albert Einstein Cardiovascular (CV) deat...
Dual Pathway Inhibition of Coagulation and Inflammation With Rivaroxaban: A New Therapy Paradigm Against Atherosclerosis
Dual Pathway Inhibition of Coagulation and Inflammation With Rivaroxaban: A New Therapy Paradigm Against Atherosclerosis
Right is right even if no one is doing it; wrong is wrong even if everyone is doing it. Saint Augustine ...
Lipid Lowering in “Very High Risk” Patients Undergoing Coronary Artery Bypass Surgery and Its Projected Reduction in Risk for Recurrent Vascular Events: A Monte Carlo Stepwise Simulation Approach
Lipid Lowering in “Very High Risk” Patients Undergoing Coronary Artery Bypass Surgery and Its Projected Reduction in Risk for Recurrent Vascular Events: A Monte Carlo Stepwise Simulation Approach
Abstract: 2018 AHA guidelines provide criteria to identify patients at very high risk (VHR) for a
Dual Pathway Inhibition with Rivaroxaban and Aspirin Reduces Inflammatory Biomarkers in Atherosclerosis
Dual Pathway Inhibition with Rivaroxaban and Aspirin Reduces Inflammatory Biomarkers in Atherosclerosis
Abstract: Dual pathway inhibition (DPI) with low-dose rivaroxaban and aspirin in patients with co
Efficacy and Safety of Clopidogrel Versus Ticagrelor for Stabilized Patients With Acute Coronary Syndromes After Percutaneous Coronary Intervention: Results From a Real-World Registry in China
Efficacy and Safety of Clopidogrel Versus Ticagrelor for Stabilized Patients With Acute Coronary Syndromes After Percutaneous Coronary Intervention: Results From a Real-World Registry in China
Background: The first 3 months after percutaneous coronary intervention (PCI) in patients with ac
One-Year Outcomes in Anticoagulated Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention: Insights From the Greek Antiplatelet Atrial Fibrillation Registry
One-Year Outcomes in Anticoagulated Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention: Insights From the Greek Antiplatelet Atrial Fibrillation Registry
Abstract: GReek-AntiPlatElet Atrial Fibrillation registry is a multicenter, observational, nonint
Apixaban and Rivaroxaban Anti-Xa Concentration Utilization in Clinical Practice
Apixaban and Rivaroxaban Anti-Xa Concentration Utilization in Clinical Practice
Abstract: Drug-specific anti-Xa concentrations can be used to assess the presence of drug effects
HDAC Inhibitors Alleviate Uric Acid–Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway
HDAC Inhibitors Alleviate Uric Acid–Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway
Abstract: Uric acid (UA) accumulation triggers endothelial dysfunction, oxidative stress, and inf
The Future for Inotropes in Heart Failure. Do Not Throw the Baby Out With the Bathwater!
The Future for Inotropes in Heart Failure. Do Not Throw the Baby Out With the Bathwater!
We listened with interest to a lively debate during the recent European Society of Cardiology (ESC) annual congress in Bar...
Mechanisms of SGLT2 Inhibitors in Heart Failure and Their Clinical Value
Mechanisms of SGLT2 Inhibitors in Heart Failure and Their Clinical Value
Abstract: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used to treat diabetes mel
Magnitude of Low-density Lipoprotein Reduction and Impact on Major Cardiovascular Outcomes
Magnitude of Low-density Lipoprotein Reduction and Impact on Major Cardiovascular Outcomes
Less is more (?) Ludwig Mies van der Rohe Atherosclerotic cardiovascular (CV) disease ...
Should We Consider Recombinant Human Brain Natriuretic Peptide to Prevent Postoperative Atrial Fibrillation?
Should We Consider Recombinant Human Brain Natriuretic Peptide to Prevent Postoperative Atrial Fibrillation?
An ounce of prevention is worth a pound of cure Benjamin Franklin Postoperative atrial...
Feedback Interaction Between Apelin and Endoplasmic Reticulum Stress in the Rat Myocardium
Feedback Interaction Between Apelin and Endoplasmic Reticulum Stress in the Rat Myocardium
Abstract: Apelin is an endogenous active peptide, playing a crucial role in regulating cardiovasc
Efficacy and Safety of Finerenone for Prevention of Cardiovascular Events in Type 2 Diabetes Mellitus With Chronic Kidney Disease: A Meta-analysis of Randomized Controlled Trials
Efficacy and Safety of Finerenone for Prevention of Cardiovascular Events in Type 2 Diabetes Mellitus With Chronic Kidney Disease: A Meta-analysis of Randomized Controlled Trials
Abstract: Only a few meta-analyses evaluated the effect of finerenone on cardiovascular events in
Silencing of Long Noncoding RNA TUG1 Ameliorates Atherosclerosis-Induced Myocardial Injury by Upregulating microRNA-30b-3p and Downregulating Brd4
Silencing of Long Noncoding RNA TUG1 Ameliorates Atherosclerosis-Induced Myocardial Injury by Upregulating microRNA-30b-3p and Downregulating Brd4
Abstract: Long noncoding RNAs and microRNAs (miRNAs) are emerging biomarkers involved in human di
Patients With High Cardiovascular Risk as Candidates to Bempedoic Acid, After Treatment With Statins, Ezetimibe and PCSK9 Inhibitors: An Estimation and Cost-Effectiveness Analysis
Patients With High Cardiovascular Risk as Candidates to Bempedoic Acid, After Treatment With Statins, Ezetimibe and PCSK9 Inhibitors: An Estimation and Cost-Effectiveness Analysis
Abstract: Low-density lipoprotein cholesterol (LDLc) is the lead effector of atherosclerosis and
Effects of Recombinant Human Brain Natriuretic Peptide on Atrial Fibrillation After Coronary Artery Bypass Grafting
Effects of Recombinant Human Brain Natriuretic Peptide on Atrial Fibrillation After Coronary Artery Bypass Grafting
Abstract: Previous studies reported that the use of natriuretic peptides (NPs) can effectively de
Management of Iron Deficiency in Heart Failure: A Review of Evidence
Management of Iron Deficiency in Heart Failure: A Review of Evidence
Abstract: Iron deficiency is common in patients with heart failure and has been associated with w
Role of Collagen in Vascular Calcification
Role of Collagen in Vascular Calcification
Abstract: Vascular calcification is a pathological process characterized by ectopic calcification
Imatinib as a Tool Against COVID-19: A Balancing Act Between Effectiveness and Cardiac Safety
Imatinib as a Tool Against COVID-19: A Balancing Act Between Effectiveness and Cardiac Safety
Heat not a furnace for your foe so hot that it do singe yourself –William Shakespeare ...
Cardiac Safety of Imatinib for the Treatment of COVID-19: A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial
Cardiac Safety of Imatinib for the Treatment of COVID-19: A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial
Abstract: Although previous studies support the clinical benefit of imatinib regarding respirator
Gab1 Overexpression Alleviates Doxorubicin-Induced Cardiac Oxidative Stress, Inflammation, and Apoptosis Through PI3K/Akt Signaling Pathway
Gab1 Overexpression Alleviates Doxorubicin-Induced Cardiac Oxidative Stress, Inflammation, and Apoptosis Through PI3K/Akt Signaling Pathway
Abstract: Grb2-associated binding protein 1 (Gab1), an intracellular scaffolding adaptor, was inv
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