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Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphomas (PGTL) are exceedingly rare with an estimated incidence of 0.0091 per 100,000 person-year...
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
A 69-year-old with well-controlled HIV was evaluated for persistent cough, in the context of years of fatigue and...
Mast cell sarcoma with KIT p.D816V mutation and concurrent systemic mastocytosis
Mast cell sarcoma with KIT p.D816V mutation and concurrent systemic mastocytosis
Mast cell sarcoma (MCS) is an extremely rare and aggressive form of mastocytosis characterized by highly atypical mast cel...
BRAF V600E mutation and high expression of PD-L1 in Rosai-Dorfman disease: case report and review of the literature
BRAF V600E mutation and high expression of PD-L1 in Rosai-Dorfman disease: case report and review of the literature
BRAF V600E mutations are frequently found in histiocytic/dendritic cell neoplasms such as Erdheim-Chester disease (ECD) an...
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Chronic myeloid leukemia (CML) typically presents in the chronic phase. The blast crisis phase in CML predominantly compri...
Follicular dendritic cell sarcoma involving the parotid gland with expression of the melanocytic marker PRAME
Follicular dendritic cell sarcoma involving the parotid gland with expression of the melanocytic marker PRAME
Follicular dendritic cell sarcoma is a rare mesenchymal neoplasm arising from follicular dendritic cells (FDC) of lymphoid...
Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement
Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma, with most cases harboring ALK gene rearra...
Complete loss of lineage defining antigens in two cases of B-cell malignancies following CAR-T therapy
Complete loss of lineage defining antigens in two cases of B-cell malignancies following CAR-T therapy
Targeted immunotherapy is a promising approach in treating high-risk and refractory/relapsed lymphoid malignancies. Althou...
Simultaneous merkel cell carcinoma and acute myeloid leukaemia: A diagnostic challenge
Simultaneous merkel cell carcinoma and acute myeloid leukaemia: A diagnostic challenge
Merkel cell carcinoma is a very aggressive primary skin tumour with a high risk of local recurrences and lymphatic and dis...
Bridging dermatology and hematology: a case of lepromatous leprosy with bone marrow involvement and pancytopenia
Bridging dermatology and hematology: a case of lepromatous leprosy with bone marrow involvement and pancytopenia
Leprosy, caused by Mycobacterium leprae (M. leprae), primarily manifests with cutaneous and peripheral nerve invo...
An unusual case of pure erythroid leukemia with normal karyotype and NPM1 mutation
An unusual case of pure erythroid leukemia with normal karyotype and NPM1 mutation
Pure erythroid leukemia (PEL) is an extremely rare subtype of acute myeloid leukemia (AML). Although not specific, PEL is ...
Paraneoplastic glomerulonephritis and kidney infiltration by mantle cell lymphoma: A diagnostic challenge
Paraneoplastic glomerulonephritis and kidney infiltration by mantle cell lymphoma: A diagnostic challenge
Mantle cell lymphoma (MCL) is a rare and aggressive type of lymphoma that can affect the kidneys. The disease can lead to ...
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Epstein-Barr virus (EBV) typically infects B cells in infectious mononucleosis (IM), but a rare case shows EBV infection i...
CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
A 51-year-old female with menorrhagia was found to have a cervical polyp. Polypectomy and endometrial curettage showed an ...
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements
Quadruple-hit lymphomas are extremely rare non-Hodgkin lymphomas with a reported dismal prognosis in the few reported case...
Transdifferentiation of diffuse large B-cell lymphoma to a poorly differentiated neoplasm following CAR T-cell therapy
Transdifferentiation of diffuse large B-cell lymphoma to a poorly differentiated neoplasm following CAR T-cell therapy
Chimeric antigen receptor T-cell (CAR-T) therapy is a recent advancement in precision medicine with promising results for ...
AI-based computational H&E staining in lymphomas
AI-based computational H&E staining in lymphomas
Ethical approval For this type of study, formal consent is not requ...
Validation of an automated iron stain process for use with bone marrow aspirate smear slides
Validation of an automated iron stain process for use with bone marrow aspirate smear slides
The assessment of bone marrow iron stores is typically performed on an aspirate smear slide that has been manually stained...