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An unusual case of pure erythroid leukemia with normal karyotype and NPM1 mutation
An unusual case of pure erythroid leukemia with normal karyotype and NPM1 mutation
Pure erythroid leukemia (PEL) is an extremely rare subtype of acute myeloid leukemia (AML). Although not specific, PEL is ...
Paraneoplastic glomerulonephritis and kidney infiltration by mantle cell lymphoma: A diagnostic challenge
Paraneoplastic glomerulonephritis and kidney infiltration by mantle cell lymphoma: A diagnostic challenge
Mantle cell lymphoma (MCL) is a rare and aggressive type of lymphoma that can affect the kidneys. The disease can lead to ...
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Epstein-Barr virus (EBV) typically infects B cells in infectious mononucleosis (IM), but a rare case shows EBV infection i...
CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
A 51-year-old female with menorrhagia was found to have a cervical polyp. Polypectomy and endometrial curettage showed an ...
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements
Quadruple-hit lymphomas are extremely rare non-Hodgkin lymphomas with a reported dismal prognosis in the few reported case...
Transdifferentiation of diffuse large B-cell lymphoma to a poorly differentiated neoplasm following CAR T-cell therapy
Transdifferentiation of diffuse large B-cell lymphoma to a poorly differentiated neoplasm following CAR T-cell therapy
Chimeric antigen receptor T-cell (CAR-T) therapy is a recent advancement in precision medicine with promising results for ...
AI-based computational H&E staining in lymphomas
AI-based computational H&E staining in lymphomas
Ethical approval For this type of study, formal consent is not requ...
Validation of an automated iron stain process for use with bone marrow aspirate smear slides
Validation of an automated iron stain process for use with bone marrow aspirate smear slides
The assessment of bone marrow iron stores is typically performed on an aspirate smear slide that has been manually stained...
What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?
What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?
The classification of tumors is essential in the diagnosis and clinical management of patients with malignant neoplasms. T...
Isolated Langerhans cell histiocytosis in the stomach of adults: four-case series and literature review
Isolated Langerhans cell histiocytosis in the stomach of adults: four-case series and literature review
Langerhans cell histiocytosis (LCH) of the stomach is rare. Moreover, it is usually found in pediatric patients with syste...
Secondary plasma cell leukaemia (PCL) with plasmablastic morphology
Secondary plasma cell leukaemia (PCL) with plasmablastic morphology
A 71-year-old female with relapsed IgA lambda myeloma developed progressive cytopenia. The peripheral blood film showed 5%...
ALK-positive large B-cell lymphoma (ALK + LBCL) with aberrant CD3 expression
ALK-positive large B-cell lymphoma (ALK + LBCL) with aberrant CD3 expression
ALK-positive ( +) large B cell lymphoma (ALK + LBCL) is a rare distinct subtype of diffuse large B cell ...
In memorium: Dr. Zeba Singh
In memorium: Dr. Zeba Singh
We are deeply saddened by the recent passing of Dr. Zeba Singh, who left us in Novem...
Cytogenetic and pathologic characterization of MYC-rearranged B-cell lymphomas in pediatric and young adult patients
Cytogenetic and pathologic characterization of MYC-rearranged B-cell lymphomas in pediatric and young adult patients
MYC-rearranged B-cell lymphoma (BCL) in the pediatric/young adult (YA) age group differs substantially in disease composit...
Gamma-delta T-cell acute lymphoblastic lymphoma/leukemia: a report of a rare entity
Gamma-delta T-cell acute lymphoblastic lymphoma/leukemia: a report of a rare entity
Gamma delta (γδ) T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) is a rare, aggressive subtype of T-lymphoi...
The first case of six-way complex translocation of t(4;7;9;22;8;14) in a patient with chronic myeloid leukemia
The first case of six-way complex translocation of t(4;7;9;22;8;14) in a patient with chronic myeloid leukemia
In chronic myeloid leukemia (CML), patients exhibit the t(9;22)(q34.1;q11.2) translocation, resulting in the formation of ...
Hemophagocytic lymphohistiocytosis caused by herpes simplex virus type 1 in a young adult: a case report with literature review
Hemophagocytic lymphohistiocytosis caused by herpes simplex virus type 1 in a young adult: a case report with literature review
Hemophagocytic lymphohistiocytosis is a severe hyperinflammatory syndrome that can be potentially life-threatening without...
Initial diagnosis of extranodal NK/T-cell lymphoma in pericardial fluid with concomitant hemophagocytic lymphohistiocytosis (HLH)
Initial diagnosis of extranodal NK/T-cell lymphoma in pericardial fluid with concomitant hemophagocytic lymphohistiocytosis (HLH)
Extranasal natural killer/T-cell lymphoma arising in the heart is rare and typically presents with non-specific clinical s...
Primary anaplastic large cell lymphoma arising from central nervous system
Primary anaplastic large cell lymphoma arising from central nervous system
A 22-year-old man presented at the emergency department with progressive headache, vomiting and horizontal diplopia over 2...
Anaplastic large cell lymphoma presenting as a mass in the uterine cervix: a case report
Anaplastic large cell lymphoma presenting as a mass in the uterine cervix: a case report
T-cell lymphoma is an extremely rare form of malignancy in the female genital tract. Most of the reported cases of lymphom...
Two cases of mycosis fungoides with large cell transformation with KMT2A rearrangements
Two cases of mycosis fungoides with large cell transformation with KMT2A rearrangements
Cutaneous T-cell lymphomas (CTCL) are a clinically and molecularly heterogeneous class of lymphomas of the skin-homing T c...
A rare case of fluid overload-associated large B-cell lymphoma and antigen loss at relapse
A rare case of fluid overload-associated large B-cell lymphoma and antigen loss at relapse
Fluid overload-associated large B-cell lymphoma (FO-LBCL) is a new addition to the list of large B-cell lymphomas in the 5...
Oral follicular lymphoma: a clinicopathologic and molecular study
Oral follicular lymphoma: a clinicopathologic and molecular study
Follicular lymphoma is a hematolymphoid neoplasm that originates from germinal center B cells. It is made up of a combinat...